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Connor Brown Profile
Connor Brown

@env_biochem

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Post-doc with @waterargome, lover of nature, biochemist of water microbes, and an okay dancer. First gen.

Joined July 2013
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@env_biochem
Connor Brown
2 months
now live: how should we relate AR indicators in sewage to community resistance? one look at this issue using deep longitudinal metagenomics, modeling, and lots of bioinformatics @waterARGome @petervikesland @AyellaMM
@medrxivpreprint
medRxiv
2 months
Metagenomics disentangles epidemiological and microbial ecological associations between community antibiotic use and antibiotic resistance indicators measured in sewage #medRxiv
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@env_biochem
Connor Brown
23 days
RT @jgi: In Science Advances: a microbial genome census from publicly available databases using publicly available genome sequence data gen…
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@env_biochem
Connor Brown
1 month
RT @davidacoil: Currently reading the very interesting "Ebolavirus evolution and emergence are associated with land use change"... a nice m…
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@env_biochem
Connor Brown
2 months
RT @pacyc1841: » Homologous recombination shapes the architecture and evolution of bacterial genomes | Nucleic Acids Research | Oxford Acad…
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@env_biochem
Connor Brown
2 months
@AllisonLopatkin @NSF amazing, so deserved!
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@env_biochem
Connor Brown
2 months
RT @ASMicrobiology: Exciting news! ASM is partnering with @IDSAInfo to launch an annual conference on #AMR. This landmark event will unite…
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@env_biochem
Connor Brown
2 months
RT @npjAMR: Antibiotic resistance mediated by gene amplifications🧬 This review is available open-access to read @npjAMR! @kptsilva @AnuKh
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@env_biochem
Connor Brown
3 months
RT @JingqiuLiao: Thrilled to share that the FIRST paper from our group is live in @NatureComms ! Kudos to my amazing students @yingxian_g ,…
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@env_biochem
Connor Brown
3 months
RT @ElanaPearl: 🧬What are protein language models (PLMs) actually learning about biology? Our paper introduces InterPLM - a framework that…
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@env_biochem
Connor Brown
4 months
RT @wc_ratcliff: New preprint up! We sequenced hundreds of samples from across one of Earth's oldest living organisms - the Pando aspen clo…
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@env_biochem
Connor Brown
4 months
RT @MarcoGabriell16: How many species of #Legionella exist? If you ask your petri dish the answer is about 75, but is this correct? And how…
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@env_biochem
Connor Brown
4 months
RT @pacyc1841: Gamma-Mobile-Trio systems are mobile elements rich in bacterial defensive and offensive tools | Nature Microbiology https://…
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@env_biochem
Connor Brown
4 months
RT @DecrolyE: "The innate antiviral defense is already preactivated in bat cells compared to human cells, suggesting that the innate immune…
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@env_biochem
Connor Brown
4 months
@jewilki @PacBio I'm curious how sequencing depth factors in here? On a per molecule basis, LR have orders of magnitude higher detection limit. In which case, much more sequencing ($$) would be needed to reach similar levels of coverage
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@env_biochem
Connor Brown
4 months
RT @JoaoFTSBotelho: Pipolins are bimodular platforms that maintain a reservoir of defense systems exchangeable with various bacterial genet…
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@env_biochem
Connor Brown
4 months
RT @nu1chan: Excited to share our new preprint! We identified a novel extrachromosomal element, named "Inocle," in the human oral microbiom…
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@env_biochem
Connor Brown
4 months
RT @npjAMR: "we observed an enrichment of #antimicrobial resistance genes in hospital wastewater; ...[genes] correlated to total prescripti…
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@env_biochem
Connor Brown
5 months
RT @waterARGome: Our recent study demonstrates how profiling microbiomes can serve as a high precision tool for assessing water quality and…
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@env_biochem
Connor Brown
5 months
@environmicrobio it is better when there are more samples - so that the library prep doesnt stall for lack/loss of DNA. We do see improvements to assembly quality, and it helps combat uncertainty around assembly. But detection limit, etc, is a real problem.
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