Edgar V. Lerma 🇵🇭
@edgarvlermamd
Followers
32K
Following
5K
Media
21K
Statuses
27K
Chicago Sports Fan... Nephrologist by day. My tweets are not medical advice. The views expressed here are my own and not those of my employer.
Riverside, IL, USA
Joined October 2009
Treatment of Hyponatremia from @NephroMD #Nephpearls #KidneyWk . 📌 Use of Hypertonic Saline (HTS).📌 Management of severely symptomatic hyponatremia.📌 Pitfalls of correction.📌 Risk factors for rapid correction . 👉
3
348
867
Hyponatremia demystified: Integrating Physiology to shape Clinical Practice ca. 2022 from @bdubNephro @ChristCrain @priti899 @NephroMD #Nephpearls . 👉🏼
9
221
646
3
243
606
3
160
594
You know you're a Nephrologist when you see this post and this is what comes to mind 🥃🍷🥂🍻🍺🍹🍸.Illustration by @md_comics
70
161
519
3
160
491
7
141
483
1
194
476
Diuretic resistance in heart failure ca. 2020 from @JACCJournals @dhekidney .#Cardiorenal #Nephpearls. 👉🏼
1
177
459
Delta ratio= (change in anion gap)/(change in bicarbonate) #Nephpearls . < 0.4: Normal AG acidosis.0.4-0.8: Mixed high ➕ normal AG acidosis.0.8-2.0: Pure high AG acidosis.> 2.0: High AG acidosis ➕ pre-existing metabolic alkalosis. 👉🏼
4
167
453
Delta ratio = (change in anion gap)/(change in bicarbonate) ca. 2007 from @JASN_News #Nephpearls . < 0.4: Normal AG acidosis.0.4-0.8: Mixed high ➕ normal AG acidosis.0.8-2.0: Pure high AG acidosis.> 2.0: High AG acidosis ➕ pre-existing metabolic alkalosis. 👉🏼
4
157
445
Preparing for a “Chronic Kidney Disease Lecture” .📌 Please recommend noteworthy publications⁉️ .Illustration Credit: @medcomic .#Nephpearls #AskRenal
39
182
418
The five types of glomerulonephritis classified by pathogenesis, activity and chronicity (GN-AC) ca. 2023 from @NDTsocial @hjanders_hans #Nephpearls. 👉🏼
4
148
427
Hypokalemia: Diagnostic algorithm.#Nephpearls. ☑️ Urine K.☑️ Serum Mg.☑️ Serum CO2.☑️ Blood Pressure.☑️ Urine Chloride.☑️ Renin, Aldosterone. 👉
3
106
437
Lupus nephritis: Management/ treatment decisions ca. 2022 from @CJASN @goKDIGO @Meyaix #Nephpearls .
0
173
421
AKI in patients with liver cirrhosis ca. 2022 from @CJASN @VelezNephHepato @SwethaKanduriMD #Nephpearls. 👉🏼
1
164
404
Diabetes Management in CKD: A Consensus Report by @AmDiabetesAssn & @goKDIGO @DiabetesCareADA ca. 2022 #Nephpearls. H/T @deboerih @gbakris @KatherineTuttl8 @P_Rossing @sylviaerosas @JoshuaNeumiller @ConnieMRhee @kamleshkhunti . 👉
0
180
399
Amlodipine vs Nifedipine #Nephpearls #HTNSecrets. 📌 In HFrEF, nifedipine use has been associated with worse long-term outcomes; whereas amlodipine appears to be safe. 👉🏼
1
127
401
Diuretics in states of volume overload: Core Curriculum ca. 2022 from @AJKDonline @JamesNovakNeph @dhekidney #Nephpearls. 👉🏼
0
139
394
Hyperdiuresis: Using hypertonic saline plus IV furosemide to facilitate diuresis #Nephpearls #Cardiorenal . 👉🏼 via @emcrit
4
142
387
Delta ratio = (change in anion gap)/(change in bicarbonate) ca. 2007 from @JASN_News #Nephpearls . < 0.4: Normal AG acidosis.0.4-0.8: Mixed high ➕ normal AG acidosis.0.8-2.0: Pure high AG acidosis.> 2.0: High AG acidosis ➕ pre-existing metabolic alkalosis. 👉🏼
5
147
389
Hyperchloremic acidosis: Algorithmic approach ca. 2016 from @AJKDonline #Nephpearls . 📌 Diarrhea.📌 Type 1 RTA.📌 Type 2 RTA.📌 Type 4 RTA. 👉
1
142
383
SGLT2 inhibitors (SGLT2i) may delay ESKD by 15 years ca. 2021 from @ASNKidney360 @DrRonWald @drjjw @NephroGuy .#Nephpearls #ERA23 .
4
136
364
2
159
354
Cardiorenal syndrome: Definitions, Hemodynamic mechanisms, Neurohormonal mechanisms.#NKFClinicals #Nephpearls . 👉
1
131
355
1
119
352
Dialysis Dysequilibrium Syndrome #Nephpearls #PathophysiologyPearls . According to the "reverse urea hypothesis," urea is unable to move freely between the extra- and intracellular spaces in neuronal tissue because of the presence of tight junctions and other components of the
2
125
351
Blood Pressure (BP) Management in the Patient with CKD ca. 2022 from @CJASN #Nephpearls. 👉🏼
0
108
343
Management of the Hemodialysis Patient with Catheter-Related Bloodstream (CRBSI) Infection ca. 2019 from @CJASN @nephrogeek1 #Nephpearls . 👉🏼
0
128
345
Respiratory acidosis and respiratory alkalosis: Core Curriculum 2023 from @AJKDonline #Nephpearls.
1
119
341
DARE-ESKD 1: Pharmacokinetic Properties of SGLT2 inhibitor (SGLT2i) Dapagliflozin in Patients on Hemodialysis and Peritoneal Dialysis ca. 2023 from @CJASN #Nephpearls . - Well tolerated .- Slightly dialyzable.- Non-accumulating pharmacokinetic properties.
2
145
336
AKI in Cirrhosis: Differential Diagnosis ca. 2024 from @AJKDonline @SwethaKanduriMD @VelezNephHepato #Hepatorenal #Nephpearls. 👉
2
147
334
The Novel Coronavirus 2019 Epidemic and Kidneys ca. 2020 . “Postulated” mechanisms: .👉🏼 Sepsis leading to cytokine storm syndrome.👉🏼 Direct cellular injury due to the virus. #nCoV19 #nCoV2019 #COVID2019 #COVID19 #CoronaKidney .👉🏼
131
223
321
Glucose-lowering agents in Type 2 Diabetes (T2D) and CKD: Indications and dose adjustments .#ISNWCN 🇲🇾 #Nephpearls
4
177
329
Contrast-associated AKI (CA-AKI): Potential risk ⚠️ factors and preventive measures from @goKDIGO .#NephJC #Nephpearls . #VisualGraphic by @JasmineNephro . 👉
4
132
328
Check out “Handbook of Critical Care Nephrology” . Proud of this work with @jaykoyner and @kidney_boy. Thanks to all the authors who contributed. Special mention to @whatsthegfr and @Stones__ for their work on #VisualAbstract .#Pioneers #EarlyAdopters. 👉🏼
20
80
316
Fluids and Electrolytes 101:. 1 Liter NS ~ 20 bags (1 oz) of Potato 🥔 Chips. Credit: @jbcarmody . #NephTrivia #Nephpearls
7
80
298
The Furosemide Stress Test accurately predicts patients who are at increased risk for:.📌 Severe AKI. 📌 Requirement for RRT. 📌 Delayed Graft Function following kidney transplantation . #Nephpearls #AKIinICU
1
123
303
.@goKDIGO 2020 Clinical Practice Guideline for Diabetes Management in CKD 🆕 #Nephpearls .👉🏼
3
143
305
Pathogenesis of "diabetic nephropathy" vs "CKD with diabetes" ca. 2017 from @NDTsocial .#ISNWCN 🇹🇭 #Nephpearls. 👉
1
91
304
Acid base disorders in the critically ill patient ca. 2022 from @CJASN @AchantiAnand #Nephpearls #AKIinICU . 👉🏼
1
103
300
RENAL LIFECYCLE Trial: Efficacy and safety of dapagliflozin 10 mg vs placebo #Nephpearls .✅ eGFR <25.✅ Patients on dialysis with residual diuresis >500 ml/24-hour.✅ Kidney transplant recipients with an eGFR </=45 . 📌 PRIMARY ENDPOINT: Composite end point of kidney failure,
4
109
300
1
113
287
Novel Therapeutics for Management of Lupus Nephritis: What Is Next? ca. 2023 from @KidneyMed @GlomCon .#Nephpearls . 👉🏼
3
108
288
Empagliflozin in Adults with CKD: Current Evidence and Place in Therapy ca. 2023 #Nephpearls .
4
108
285
Diuretics in states of volume overload ca. 2022 from @AJKDonline @JamesNovakNeph @dhekidney #Nephpearls #Cardiorenal . 👉🏼
3
120
278
1
95
279
Amlodipine vs Nifedipine #Nephpearls #HTNSecrets. 📌 In HFrEF, nifedipine use has been associated with worse long-term outcomes; whereas amlodipine appears to be safe. 👉
3
91
274
5
91
271
Updates on Membranous Nephropathy: The ability to measure specific autoantibodies in MN in clinical practice has opened a new window onto the immunologic course of the disease. #SSCP22 🇸🇦 #SSCP 🇸🇦 #Nephpearls
0
99
273
DAPA-CKD: SGLT2 inhibitors in IgA Nephropathy and FSGS. IgA Nephropathy FSGS.
1
112
271
Management of the Patient on Hemodialysis with Catheter-Related Bloodstream Infection (CRBSI) ca. 2019 from @CJASN @nephrogeek1 @MikeAllonK360 #Nephpearls . 👉🏼
0
104
266
0
97
262
Reposting “Mechanisms of Diuretic Resistance” from @NishaKidneyDoc @HeartDocSadiya @DrFlashHeart. 🎨 Infographic by @hellokidneyMD - Winner of @NephJC @CJASN #VisualAbstract of the Year 2022. #KidneyWk #Nephpearls. 👉🏼
2
97
263
The diagnosis and treatment of #Hepatorenal syndrome is not typically straightforward . I highly recommend 👍🏼👍🏼👍🏼 this review article by @VelezNephHepato #Nephpearls . 👉🏼
3
110
266
Hypokalemia and alkalosis syndromes (and Gordon syndrome) from @RenalFellowNtwk #Nephpearls #HTNSecrets . Credit: Anthony Provenzano . 👉🏼
0
80
267
Hypokalemia and alkalosis syndromes (and Gordon syndrome) from @RenalFellowNtwk #Nephpearls #HTNSecrets . Credit: Anthony Provenzano . 👉🏼
1
104
266
Management of the Hemodialysis Patient with Catheter-Related Bloodstream (CRBSI) Infection ca. 2019 from @CJASN @nephrogeek1 #Nephpearls . 👉🏼
0
80
260
Clinical Practice Guideline for the Management of Lupus Nephritis ca. 2024 from @goKDIGO #Nephpearls . 📌 Immunosuppressive treatment for patients with Class I or Class II lupus nephritis.📌 Recommended approach for initial therapy of active Class III/IV lupus nephritis.📌
2
113
263
Hypokalemia➕Hypomagnesemia: Role of magnesium in ROMK channel function. 📌 Why magnesium repletion is required to efficiently restore potassium concentrations to normal during concomitant hypomagnesemia and hypokalemia.#Nephpearls . 👉
2
102
264
Diagnostic approach to the patient with kidney cysts from @fouadchebib .#NKFClinicals 🇺🇸 #Nephpearls
2
97
266
EMPA-KIDNEY: Among a wide range of patients w/ CKD who were at risk for disease progression, empagliflozin therapy led to a lower risk of progression of kidney disease or death from CV causes (vs. placebo) ca. 2022 from @NEJM #KidneyWk #Nephpearls . 👉🏼
3
105
243
1
93
247
When I first became a Nephrology Fellow @NU_Nephrology in 1998, one of my mentors Dr. Del Greco gave me the 1st edition of this book. In 2000, Dr. Batlle gave me the 2nd edition as a graduation gift. 4 editions later -. #HealthXPH 🇵🇭 #Mentoring
18
14
250
New aspects in #cardiorenal syndrome and HFpEF ca. 2022 from @CKJsocial @PepaSolerR #Nephpearls . 👉🏼
3
106
246
Rituximab Resistance in Glomerular Diseases: A @GlomCon Mini-Review ca. 2024 from @KidneyMed @TaniaSalehi @AlJurdi @NWiegley @nikkonephro #Nephpearls. 📌 Mechanisms of rituximab resistance.📌 Clinical approach to diagnosis and management of rituximab resistance. 👉🏼
3
95
243
Hyperkalemia: Definitions and Management from @RPANephrology @ISNkidneycare @goKDIGO @escardio @ASPCardio .#Nephpearls #Cardiorenal #RPA24 #RPA2024. 👉
0
115
246
Rhabdomyolysis induced AKI: Key 🔑 pathobiological processes and management interventions ca. 2023 from @CJASN @javo_neyra #Nephpearls .
2
92
244
Which patients with CKD are candidates for SGLT2 inhibitors: Cold 🥶 Map #Nephpearls .@hswapnil @ChristosArgyrop . 👉
2
74
243
