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Don Layman
@donlayman
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Professor of Nutrition (emeritus) University of Illinois. focus on protein for “muscle-centric” health https://t.co/6yu7QYAn1z
Chicago, IL
Joined January 2011
RT @bigfatsurprise: Weight loss is better on a diet higher in protein than the amount recommended by the Dietary Guidelines. Complete prot…
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@tednaiman @exfatloss Hey guys, are we missing context of defining "high." I have done hundreds of comparisons RDA 0.8 g/kg vs 1.6 and I have never seen a high BUN. I assumed @drdairy50 was asking me about ranges normally recommended. Define levels where you see elevated BUN
@donlayman BUN remains [harmlessly] elevated indefinitely on high protein diets. As long as you are eating more protein than the average person, you are going to have higher BUN than the average person. 😁🙌🏼
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No, BUN stays stable across wide range of protein intakes. But if a person goes from low protein diet to high, often see a transient increase in blood urea. Takes 5 to 7 days to adapt to different protein intake
@donlayman Are there studies looking a the impact of high protein diets on BUN? Does it increase? Is that bad?
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Nina is 100% correct. Our family farms & food quality are at risk under false claims about animal-derived foods, saturated fats & the environment. It’s time for the truth
Hold these two thoughts in your head: --There's been a relentless crusade to frame the food system as "broken" and in need of wholesale "replacement" using radical measures. It's urgent. Moonshots are needed. AND --Family farms in Europe and the US are disappearing at alarming rates See what's wrong here? We KNOW how to produce healthy foods--meat, eggs, dairy--but farmers/ranchers have been relentlessly hit with govt regulations, phony campaigns to say their products are unhealthy and responsible for climate change, etc. These are false claims. All this, I believe, is to make way for the new "future of food"--new fake-food products, ultra-processed foods, and other food-like substances that will profit large corporations. For instance, a recent letter signed by 150 notables, sponsored by the World Food Prize Foundation, says we need more investment in "the creation of nutrient-rich food from microorganisms and fungi." Also, there's the issue of control of the food systems. Corporate, centralized vs. independent, autonomous. The narrative that our "broken" food system needs replacing is just that--a narrative. Created to shift to more centralized food systems that yield more corporate profits. We have, for millennia, known how to raise/grow healthy food. We need to make THIS more sustainable. 🐄🐏🍳
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RT @bigfatsurprise: Davos elites are not giving up on the nutritionally deficient EAT-Lancet diet, which pushes people towards a 'planet-sa…
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RT @GrassBased: Our grazing lands are ranked among our most vulnerable and endangered ecosystems due primarily to urban and industrial expa…
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Hanging out and recording with my best friend @drgabriellelyon stay tuned for our next podcasts
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Yes, Leu is most potent activator but more limiting in adults over 35. It's a threshold effect. Need ~3g for MPS. In younger individuals MPS is linear with amount of Leu. Insulin is also anabolic during growth but minimal effect in adults. Leu impact is different at 65 vs 25.
@donlayman Last time I checked, Leucine was the biggest activator
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Exercise, hormones & protein are all signals to mTOR but the signals are irrelevant without protein (amino acids) to make PS run. EX makes the system more efficient but protein is most important
@exfatloss @rrektcapital @donlayman I read somewhere that exercise does stimulate mTOR, but nowhere to the degree that eating protein does. The difference was 4-5 fold. I can't find the paper, though.
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Perfect question. We use ideal or “target” body weight because very few people have true values for lean mass. BW values for dietary protein assume body composition of 75% LBM. That’s true for RDA also
@donlayman Body weight or lean mass?
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Thank you. two minutes is a very narrow window to say something meaningful
@donlayman Watching your comments on the USDA's public hearing about the dietary guidelines. Well done! Thank you!
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Important question. We base protein amount on “target” weight not current weight
Presumably this doesn't scale with obesity? I find this makes "protein per weight" difficult; most numbers aren't given per lean mass and many don't know their lean mass. Do you use something like "per optimal/normal weight" maybe? These studies tend to be done in young, healthy weight people who are probably 15-25% body fat (men).
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RT @exfatloss: @donlayman Presumably this doesn't scale with obesity? I find this makes "protein per weight" difficult; most numbers aren't…
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Intense activity also burns amino acids (especially BCAA) at a rate of about 10 g/ hour. Distance runners have a much need for extra protein as body builders
@rrektcapital @donlayman The couch people need to cram down protein to activate mTOR cause exercise never will, the pro athletes need enough protein cause they're mTORing all day anyway, and need to provide the building blocks?
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I recommend a functional range of 1.2 to 2.2 g/kg. For normal healthy adult I target 1.6 g/kg (approx 0.75 g/lbs)
@donlayman Could you reiterate what you think an optimal protein amount would be for a "normal, healthy" person who isn't inactive but also not a professional athlete/bodybuilder? I.e. what most of us should probably strive for?
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Important point. Exercise effect is “U”- shape curve for protein. Moderate Ex makes protein use more efficient. Hi Ex and sedentary lifestyles both increase protein needs
Given how most people are not physically active young males, I'd suspect most people need less protein then? Sure, vegans eat 20% more to be sure (low protein quality).
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RDA defined as minimum to prevent detectable deficiency but for protein it is nitrogen balance in young males, physically active, ideal wt & eating high quality protein. Age, PA & Prot quality all affect true value for individuals
@KetoCarnivore @exfatloss @sudas1891 @DikemanDave @Leo_Abstract @charbrisc @AKoutnik @raphaels7 @CarnivoreAugust @SBakerMD @Mikejulian26 As I understand it, the RDA is supposed to be a bare minimum floor for people. I've heard @donlayman talk extensively about this before.
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I agree. Did anyone ever wonder why the Dietary Guidelines call their diet the “Heathy” Mediterranean Diet? They discovered the typical Mediterranean diet contains a lot more saturated fat and red meat than their theoretical version & more than typically consumed in the US
The Mediterranean diet promoted here in the US is a total scam. Here are 5 things that are just not true. Claim: The Med diet is all about whole grains! Reality: Italians do not eat whole-grain pasta. Pasta in Italy is made with white durum wheat. Claim: The Med diet is plant strong. Reality: Italians do not eat a plant-based diet. They are surrounded by the ocean and so eat lots of seafood, and they raise all kinds of grazing mammals (goats, sheep, cattle) as well as pigs. Claim: The Med diet is low in saturated fat. Reality: Italians love their olive oil, but they also love butter and cheese, especially in the North, where dairying was more popular than in the South due to the climatological and geographic differences between N and S. Claim: The fats in the Med diet come mainly from plants, including seeds. Reality: Italians do not get a lot of their dietary fat from seeds. They do eat some, sure, but it's not like a staple. Claim: The Med diet includes small amounts of pork. Reality: According to what's available on menus and what's in cookbooks, Italians eat a lot of pork. Hello prosciutto, salami, sausages, and pancetta. Just check out any website on traditional pork dishes: Claim: Italians eat nonfat Greek yogurt. Reality: Not even the Greeks eat nonfat Greek yogurt. Here's a University "peer review research supported" website that contains all of this misinformation:
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RT @drcateshanahan: The Mediterranean diet promoted here in the US is a total scam. Here are 5 things that are just not true. Claim: The M…
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Thanks Sara. Important information. Wheat has very poor protein quality and bioavailability is <70 %. Based on functional availability of Lysine the 17g has a value of about 8g. Leu, Trp & Thr also deficient
Global per capita protein supply in 2022 was 91 g/person/d -- this is before adjusting for food loss/waste. Number 1 source is wheat and wheat products at 17 g/d.
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