So pleased to have the paper out, available here: For me this was discovery science as I had always hoped it would be. Unpredictable, a lot of fun, and some proper detective work with plenty of twists & turns on the way. Brief thread below 🧵

@S_J_Aitken @mst_paralogue Thanks! I distinctly remember our conversations about it on the bus in Heidelberg in 2019 when I just had the single 'phylogeny-violating variant' in early embryogenesis that we'd been puzzling over... Instrumental in getting thoughts straight on the ideas

RT @S_J_Aitken: @doctor_msc @mst_paralogue Congratulations on your elegant paper! It's great to see #LesionSegregation being identified in…

@craigandersn Thanks Craig! Very much building on the ideas from you & your team..

RT @TimePieChina: In a paradigm shift in how we view mutations, researchers uncover forms of DNA damage in healthy cells that can persist u…

RT @sangerinstitute: DNA damage can go unrepaired for years, which can create multiple chances to generate harmful mutations that could lea…

A huge thank you to Peter Campbell, my supervisor whose insights were vital to getting this study started. When I showed him the 1st unexpected mutation he said (typically) ‘I wondered if this might happen..’ Also, thanks to @imartincorena & @TimCoorens for valuable input.

RT @QMBCI: 📰 Some forms of DNA damage linger unrepaired in healthy cells for years, according to a @Nature study led by Dr Mike Spencer Cha…

RT @S_J_Aitken: Building on our discovery of #LesionSegregation, @doctor_msc and colleagues from @sangerinstitute find that some DNA lesion…