Michael Bigger
@biggercapital
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Chief Recluse at Bigger Capital (Founder), District 2 Capital (D2C) Co-founder. Deep Value Investor. In solitude ...
Las Vegas, NV
Joined July 2009
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To all that laughed at me in 2013 when I bought $PLUG ... GO F .... YOURSELVES
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3 to 4 years ordeal now over. Hit the bottom recently. I’m a lucky bastard. I am all good now. My Payback to society is to focus on my powers to make promising therapeutics like DC-VAX cross the finish line. Cancer really fucks you up at time scale that are longer than expected
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What has been accomplished has profound implications for humanity. Hard to comprehend the magnitude. $NWBO
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The shit I invest in is very risky, go whine somewhere else if a few of my holdings get whacked. I don't give a shit.
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The $NWBO neoantigen database is an AI treasure trove. After the application is submitted to the MAA, we will not hesitate to move to an activist position to unlock the value if required.
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Spent about an hour with Dr. Ashkan Going to share some A+ stuff as soon as I’m back to the surface. $NWBO
#GBM
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Expect combinations partnerships. “I am optimistic we can build upon this going forward; investigating combination of DCVax-®L with other emerging therapies for glioblastomas.” - King's College Hospital NHS Foundation Trust $NWBO
#ALLSOLIDTUMORS
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Biotech Media Mafia .... Good luck trying to take down that Brown Neuro Video. Fuckers! $NWBO
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Did you know the New York Academy of Sciences Peer (5 top medical scientist) reviewed the data before approving the May 10th presentation? Blogger or top rated doctors members of the Academy? $NWBO
#GBM
@almusella
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$CROX was the big upcoming story in shoes, $PLUG was the big upcoming story in industrial energy, $NWBO is the big upcoming biotech story now. MIA approval means the company can’t be killed. GOING ALL IN ON ALL SOLID TUMORS
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Mind Blown by Compassionate Cases Data. 10 yrs
#GBM
survivors a heck of a benefit to society. $NWBO Safe with Benefits = APPROVAL
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Keytruda is a key for a few rooms in
#cancer
space, DC-VAX with FLASKWORKS is a whole house. $NWBO
#allsolidtumors
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From $NWBO is a fraud, to the data was buried, to the vaccine doesn't target neo-antigens, to they peaked at the data to now .... it's a dumb vaccine. Everything is being tried to keep stock price down. Manipulation?
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I heard Dr. Ashkan was crying of joy when they told him the final results. $NWBO
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You can’t fake the tail at > 5 years. SOC has no tail. I can’t wait to read the full set of data especially at > 5 years $NWBO
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The company, the advocacy groups and the patients will join together and go to war to crush our enemies and bring the therapeutics to patients! $NWBO
#GBM
@AlMusella
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When $MRK decides (not if but when) to go batshit on combining Keytruda with DC-VAX $NWBO will be ready with scaled up production
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$NWBO investors .. welcome the negativity. Polarization is an indication of what’s at stake .. massive potential. $AMZN 2001 $PCLN 2003 $CROX 2009 $PLUG 2013 .. Being ignored an indication of mediocrity.
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$NWBO with it FlaskWorks contraption is a weapon of mass cancer patent portfolio protection for big pharma. Combo device-therapeutics near impossible to genericize
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No one in his right mind will lend $15 million to $NWBO without signing an NDA. INFORMATION ENTROPY!!!!!!
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FlaskWorks + Dendritic Cells .... a massively disruptive biotech technology. They'll get the idea soon. $NWBO
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$NWBO AGM is in June. I want a commitment from all Board Members that they are committed to bring the fight to them. If you can’t commit, get out.
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A lot of confidence in Murcidencel being approved. $NWBO
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The $NWBO DC-Vax constant. No regulatory agency wants to be a murderer. Long term survivors and safe undeniable.
#GBM
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It's not the time to back out of the
#GBM
fight and post less about it. Let's double our effort. The
#GBM
advocacy groups and the patients are joining the fight. Stay Tuned!
@BrainTumourOrg
$NWBO
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"New Standard of Care" are powerful words "This is the first drug trial since the introduction of temozolomide that has shown a meaningful improvement in survival, and that could represent the new standard of care for our patients.“ Jenkinson $NWBO
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When the door opens to the adjacent possible, we must kick it open full force. Bringing murcidencel to patients a must. $NWBO
#braincancer
#gbm
This was my Ashley’s radiation mask, which was bolted to a table. to keep her head perfectly still. Ashley was only 11 years old. No Child should ever have to experience this. We MUST advocate, support & help our Children that so desperately NEED our Voices.
💔
#BrainCancer
💔
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@MDendream
If they get FlaskWorks to reduce manufacturing cost by 90% (target) then the
#cancer
world will flip upside down. The disruption will create an earthquake $NWBO
#GBM
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$NWBO
2 catalysts :
1. Commercial Application and Approval
2. Pay attention to the word Combos in the next couple of months
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“EXTERNAL CONTROLS ARE APPROVED BY MHRA!!!”
#TRUTH
#BIGDEAL
Can’t be denied by the pretend statisticians
@statnews
@rickberke
and the Biotech Media Mafia $NWBO
$NWBO
EXTERNAL CONTROLS ARE APPROVED BY MHRA!!!
DCVax-L is about to be approved by MHRA in UK.
Where will you kick the can now doubters? 🤔
It is all about patience. Has been for a long time.
🚀🚀🚀
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UCLA all in on
#DCVAX
confirmed. TLD amazing, full data set must be incredible. The trial is a resounding success
#GBM
3pm Saturday at
#ASCO22
$NWBO
Dr. Phioanh Leia Nghiemphu, Professor and Vice Chair of Academic Affairs at
@UCLANeurology
mentioned, "There are various vaccines that have been in clinical trials. Here at UCLA we use a DCVax..."
1.
2.
#DCVax
-L $NWBO
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DV-VAX so failed that Linda Liau using Murcidencel (potential commercial name for DC-VAX) in this Abstract.
@statnews
has some explaining to do. $NWBO
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The delta between the May 10th "The Trial Failed" narrative and today's MHRA announcement is maliciousness and market manipulation ... In my opinion, it will be prosecuted $NWBO
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Let me get that straight Naked Short Seller on
@FINRA
Board. Are you fuckin kidding me? $NWBO
#finrafraud
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In the case of $NWBO you have 70 top neuro oncologists putting their names on the JAMA peer reviewed article and no speed bumps on the road of hate.
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Anything in
#Cancer
land bigger than a Dendritic Cell Vaccine created in a FlaskWorks Contraption? $NWBO
#GBM
#ALLSOLIDTUMORS
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The whole short thesis resides on the shoulder of Pseudo Progression … A bridge made of straws. Might work in the noise space, but at the Agencies not a chance. A classic immune response, an indication the patient system is fighting back Patients first bs last $NWBO
@AlMusella
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Bought $1.0 million $SYSX convertible notes. Now long $4.0 million
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Hoping my next post is Adam go fuck yourself. $NWBO
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Liau was blinded to both the data and
#Flaskworks
, and she described what an $AMZN ish and $UBER ish would look like in this space. $NWBO delivers on both vectors. Holy F…N Shit
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$NWBO trying as hard as it can to scale up safe and efficacious
#DCVAX
which would help patients and speed up combo discoveries the like Dr. Linda Liau is pursuing. Why putting a stick in that wheel? Dumb, fat, Adam please do tell.
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Actually, we want all Cancer patients to join the fight. It's a fight against evil preventing much needed therapeutics to reach them.
@AlMusella
$NWBO
#GBM
#ALLSOLIDTUMORS
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Did you know some members of the Academy and Dr. Linda Liau have been threatened in the past few weeks? $NWBO
#GBM
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You may like or despise Linda Powers and Les Goldman, but to bring $NWBO technology for the benefit of 450-500
#GBM
patients pa in the UK is unquestionably an herculean task. If I were in there shoes, you would have found me crying in a corner since 2015
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She’s crushing the 1%. The 70 authors of JAMA peer reviewed article crushing the 0.01%? Doers and blogger yappers. $NWBO
Great site published by a Dr. L. on iHub. Linda Liau really is among the best of the best in the world! 🌍 $nwbo
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Bullet
#4
enigma resolved …
This is an interesting diagram, courtesy of Dr. Linda Liau and
@AlMusella
. When I read this graph, I see >50% probability of survival at 2 years among patients with rGBM who were treated with adjuvant
#murcidencel
+ a PD-1 monoclonal antibody such as
#pembrolizumab
. WOW! $NWBO
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It’s day 1 for $NWBO
“Did not have its own control arm and instead presented external control data” $NWBO
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Incredible Value Delivered to Society! Watershed Event. $NWBO
Sawston is "Going live!" according to Kelly Balsom, Head of production at Advent Bioservices 2 days ago!!
$NWBO
#DCVax
-L is available IMMEDIATELY via the UK Specials programme with Dr. Keyoumars Ashkan!!
The DCVax® Platform For All Solid Tumor Cancers
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There is no reimbursement code for luxury good companies and their businesses are massive. Even without reimbursement in the short run
#DCVAX
opportunity massive at the global scale. You can’t prevent water from flowing where it wants to go. $NWBO
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They’re dragging AF into the discovery process. Shit for brain about to hit the fan. $NWBO
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I could have caved under peer pressures not to invest in penny stocks with $PLUG at $0.23 or $CROX at $0.90 or $PCLN at $1.5. The trick is to not give a shit
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October 2022 210 lbs. Finally made it to below 170. Just finished trekking up Windy Peak, NV. I think I lost 3 pounds today. Biking, skiing, skinning, walking, working out on FitCoach app.
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I want to hear from $NWBO how they’ll get to revenues after MHRA Approval (binary) in a presentation posted to the company’s website. Don’t waste my time yapping the lawsuit, I only care about the Judge’s decision.
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If in the filing, might be a done deal, like the latest 10Q and the potential lawsuit. "(i) potential combinations with a wide range of other types of treatments; (ii) potential application to any type of solid tumor (i.e., a tumor in any tissue)" $NWBO
#GBM
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Must pin!
The End Brain Cancer Initiative (EBCI) is advocating for FDA approval of DCVax-L®, a novel treatment for Glioblastoma (GBM) brain tumors, in anticipation of submittal of the application for FDA approval by Northwest Biotherapeutics. Read Press Release: .
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Because capacity is constrained, Big Pharma will act quickly to lock in supply for combo trials $NWBO
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The sinking ship is
@statnews
with the fatty weight in its underbelly $NWBO
She is too smart to join a sinking ship. Dr. Liau’s guidance on future combinations will be essential to a nimble approach to investigation. $NWBO
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Just want to remind the naysayers about buying $CROX at $0.90 in 2009, the stock is currently trading at $94 today. I love these ugly shoes! 100 to 1
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Investors have a right to get access to coordinated communication between journalists….market makers….and hedge funds in an 8–K type of format when a May 10 type of move happens. If it’s material it should be on the Federal system $NWBO
@statnews
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From 13% to 20% Overall Survival at 5 years … might be a possible achievement by iterating and innovating on it especially given its safety profile. It would be a human tragedy not to open this door. $NWBO
@AlMusella
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Count me in the Vegas Ape 🦍 Community. $NWBO
My mother is a strong, intelligent, beautiful woman & also a cancer survivor.
So my blood is still boiling over MMs like Citadel spoofing a potential "breakthrough" in cancer treatment 😡😡😡 Apes will break you Kenny🦍🦍🦍
#CitadelScandal
#NWBO
#AMC
#GME
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@StylianosIkono1
All I can say is that if $NWBO is successful bringing DC-VAX to patients, it will be my biggest contribution regardless of how much money I make with it. Obsessing over bringing this all solid tumor therapeutics across finish line a crowning achievement. I don’t care about the
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Is Linda Powers trying to Peter Minuit a Dendritic Cells Manhattan? $NWBO
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DC-Vax three of the top neurosurgeons in the world on the road pounding the table regarding its benefits. $NWBO
#GBM
#cancer
#allsolidtumors
Dr. Prof. Keyoumars Ashkan presenting at the Advanced Therapies Symposium by King's College Hospital NHS Foundation Trust on Friday, September 9, 2022 - "Dendritic cell vaccination for glioblastoma" $NWBO
#DCVax
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@SamanthaTwenty
@DakotasTwits
@DaiichiSankyoUS
Samantha reach out to
@AlMusella
and Dr. Ashkan at Kings College Happy to make an introduction to Dr. Ashkan to speed things up. DM me
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The decision to not halt $NWBO on May 10 will come under scrutiny. This is getting better by the second
@finra
#finrafraud
$NWBO
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