1/🧬 Excited to share PLAID, our new approach for co-generating sequence and all-atom protein structures by sampling from the latent space of ESMFold. This requires only sequences during training, which unlocks more data and annotations: 🧵

@EmiliaHojelP made lecture slides for AF2 a while back -- hope this could be helpful!

RT @aditimerch: Excited to have the first project of my PhD out!!! By leveraging Evo's ability to learn relationships across genes (i.e., "…

@d_yuqing 🌟🌟🌟

RT @workshopmlsb: Next up - Contributed Talk! Protein Language Model Fitness is a Matter of Preference @CadeGordonML @amyxlu @pabbeel

thanks @workshopmlsb for letting us share our work!! 🔗📄

😅

RT @nc_frey: New blog post with @asalam_91 on our recent work, which introduces a fundamentally new way to build foundation models that are…

@KevinKaichuang @jsci I too think a model can predict the state of folded laundry, but the difficulty of that task seems vastly easier than folding a protein (for a mere mortal like me)

@j_asminewang instead of calling it 'daylight savings' we call it 'daylight wastings' in the winter and permanently turn back the clock

@314duckEon ESMFold is a protein folding model (problem setting is essentially the same as AlphaFold). We take the output of a specific intermediate layer, and learn a generative model to generate that embedding, to design new proteins. Hope that helps!

@ginaelnesr @workshopmlsb Excited for the workshop!! 💃ty for helping put it together

@chaitjo Thank you @chaitjo!! Hope to catch ya soon 😊

@amelie_iska @KevinKaichuang @amelie_iska you read our minds ;) if anyone would want to collaborate on this, give one of us a ping!

RT @nc_frey: Two @NeurIPSConf workshop spotlight talks from our lab this year! @amyxlu will present on all-atom protein generation from se…

RT @KevinKaichuang: We trained a model to co-generate protein sequence and structure by working in the ESMFold latent space, which encodes…

RT @nc_frey: Join us in NYC as a graduate student intern @PrescientDesign, @genentech this summer to work on fundamental research in 3D gen…

@dr_alphalyrae thanks so much Vega!

RT @BiologyAIDaily: Generating All-Atom Protein Structure from Sequence-Only Training Data • PLAID (Protein Latent Induced Diffusion) intr…

RT @nc_frey: Incredible work led by @amyxlu introducing PLAID, an all-atom co-generation method for proteins that requires only sequence in…