Solving Aging Quest!
@valleerl
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Goal? Solving aging! I believe in free speech, I just don’t like X. Here my new place:
Canada
Joined August 2010
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I believe the quickest way to achieve biological immortality in the short term would be to replace our existing cells with our own, but younger, cells.
If you disagree, what's in your opinion the fastest method to achieve biological immortality from today?
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Here's my draft for the new plan to solve aging:
1. Extract a somatic cell from an individual.
2. Correct its DNA damage in the laboratory (5-10 years younger).
3. Extend the cell's telomeres (5-10 years younger).
4. Apply epigenetic adjustments (5-10 years younger).
5. Convert
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The reason I believe the solution closest to achieving biological immortality involves regenerating the human body's systems by priority with our own cells, is that all currently available solutions fail to regenerate the cytoplasm, that’s crucial for extra cellular communication
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Rejuvenation Machine (Step 1) 🤩
Preserve annually 4 stem cell types via cryotherapy:
Endothelial, Mesenchymal, Pericyte, Hematopoietic.
Thaw later, inject younger cells to regenerate venous system, replacing and eliminating older cells. To get younger, year by year. 🥂
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Cells rejuvenation model:
1. Telomere lengthening.
2. DNA repair.
3. Gradual epigenetic correction to optimize extracellular communication.
4. Cytoplasm revitalization (also include mitochondria + detox).
5. Selective senescent cell removal.
Is something missing? 🤔
No 🤩
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Yes, I will comment 🗣️
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I don’t know 🤷♀️
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Solving aging is becoming increasingly popular and fashionable.
@sama
Thank you for the visibility to our community! 🤩🤩🤩 Business Insider !
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Rejuvenation machine: Autologous differentiated cell therapy innovates by temporarily boosting telomerase for telomere extension, then reverting to normal levels. Enables DNA repair, cytoplasm rejuvenation, and rigorous quality checks to safely to replace aged cells in the body.
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Soon, I hope, I will be able to work almost FULL TIME on solving aging! 🤞
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BIOLOGICAL IMMORTALITY Proposition
Regenerate the body by prioritizing the regeneration of its vital systems to combat aging
Using AUTOLOGOUS CELL THERAPY we multiply and reintroduce a patient's own stem cells, preserved and collected annually in cryotherapy back into their body
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Please post something in the field of longevity that could impress me. 😂
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Why “Biological Immortality”?
I believe that one day we will understand the workings of cells so well that we will reach a point where they can self-correct and self-regenerate in a way that we will no longer be biologically mortal. That's why I call this biological immortality
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In my vision of biological immortality, people having high-performance mobile cryotherapy fridges at home to preserve their stem cells. 😂Every local pharmacy would offer services to extract these. These would be preserved annually so that individuals could regenerate themselves.
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@Teslaconomics
@elonmusk
@Noahhweb3
@SawyerMerritt
@ajtourville
I like blue, because it’s like the bird fly in the sky… X, for SpaceX.. 🤷♀️
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What is a Biodegradable Scaffold? 🤩
- Disintegrate naturally.
- Support tissue growth.
- Aid tissue repair.
Approved by FDA for specific applications:
1.Bone repair and regeneration
2.Tissue engineering
3.Cartilage repair
regeneration
For more
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Tell me if you know someone or a company that has a complete potential plan for biological immortality
Except me 😂
If you don’t, please give this post a like 👍🏻🙌😄
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There are so many credible and well-known scientific articles on the subject of fasting and autophagy. There are so many health benefits. But it remains that fasting is so difficult to do. It's a real struggle. 😂
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Regeneration with younger cells 🤩
When I started the solving aging project, I often felt like an hamster, it was hard. But now, with the help and support of many, I see it's achievable. There's light at the end of the tunnel. Thank you to everyone who helped me. 🥂🔥
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From a normal conversation:
What would you like to do in your life?
Me: Solve aging to save billions of people from death...
And you? 😂
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Prototype: Rejuvenation machine
⁃Extract a cell
⁃Rejuvenated it in laboratory
⁃Multiply it
⁃Reintroduce it in the body
⁃Kill old cells
I will detail more each points so you could verify the validity of the concept yourself.
I believe the quickest way to achieve biological immortality in the short term would be to replace our existing cells with our own, but younger, cells.
If you disagree, what's in your opinion the fastest method to achieve biological immortality from today?
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I'm currently working on visual models to address aging. I'll share them once completed. ✅🙌🙌
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Could it be done with rejuvenate cells? 🤩🤔
A study has found that three proteins in mice can transform non-limb-forming cells into limb progenitor cells, opening prospects for regenerating lost or damaged limbs. 🤯
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Why do I believe in an autologous therapy rejuvenation machine?
Optimizing cells rejuvenation process "ex vivo" before "in vivo" application can reduce risks and enhance gene therapies. "Ex vivo": modifying cells outside the body. "In vivo": gene therapy within the organism.
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I have a new idea that could lead to biological immortality. I'll discuss it soon. "Soon" is relative, though 😂
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Would you like biological immortality to be accessible?
I'm referring to the ability to prevent aging when you're young and the possibility to rejuvenate when you're older.
If not, please share your reasons in the comments.
Yes
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No
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I've been working really hard on something for a long time, and soon it should come to fruition. I truly hope it works out. I certainly deserve it. 🧎♀️🙏🤞
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AI people… invest in health! What is the greatest value you can give to any human being on Earth?
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If people live longer in a healthy way, it’s going to boost the economy. There will be more money in the market, including in cryptocurrencies.
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Is there anything more challenging than solving aging?
Absolutely not!
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Yes (just joking) 🤪
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Yes, I’m serious -comment
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XPRIZE Healthspan competition 101$ millions
I think the point on muscles rejuvenation is a little easy? 🤪🤔
Even at 80, muscles retain a remarkable capacity for rejuvenation: with proper training and nutrition, it is possible to significantly increase muscle mass, approaching
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Based on the survey results, we will keep the name "Solving Aging" and prioritize posting about current/emerging technologies, promising drugs, and drug-free methods for rejuvenation. Thank you! 😊
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Okay, I won't hide it from you. I am going to create a machine that will completely regenerate the human body. 🤩🔥🤩
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Mine! Longevity research:
-Corina Amor: targeting senescent cells via immunotherapy
-Dr. Michael Levin: rejuvenation research with bioelectricity
From Harvard Medical:
-G. Church, V. Gladyshev, D. Sinclair
Founded key orgs:
-Aubrey de Grey
Slowing down aging:
-Bryan Johnson
Could you tag your favorite longevity star and tell me why? I’ll share mine after… 😂
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In my opinion, the idea of modifying cells in the laboratory to reinsert them into the body later is the best idea, as it would also allow for correcting anomalies in the DNA sequence or selecting, for example, the cells that would be least damaged. This would also, probably in
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I am aware that when I talk about feminism, I become less popular and receive less appreciation. 😞 But that doesn’t bother me. I’d rather have fewer people following me, but people I consider of quality and with the same values as me.
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Could you tag your favorite longevity star and tell me why? I’ll share mine after… 😂
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Merry Christmas to everyone!! 🥂
I hope that for the coming new year, there will be many concrete concepts to solve aging as a whole!
Not just progress to solve the symptoms which do not address the problem at its source.
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Plan to combat aging through genetics 🧬:
1.Identify all genes related to DNA repair mechanisms.
2.Check the integrity of these genes.
•If damaged, repair them.
3.Adjust the epigenetics of all genes related to DNA repair for optimal functionality, whether they’ve been repaired
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Asking the universe (and soon, AGI, that will do everything for me😂)🙏: I would like to know to what extent you can rejuvenate a cell so that it still maintains coherent communication and interaction with others, and I would like to be able to do this using software.
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⚡️Breaking ⚡️😆
My new strategy involves finding software that allows for the simulation of cellular behavior to advance my research. This approach would enable me to bypass the initial laboratory need, which is costly and complex. For example, I could simulate the impact of
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My next post will be about the cell and its functionality, that is, how we could optimize corrections to rejuvenate cells, but in a way that it's not a colossal task, or at least so that the complexity of such a task is reduced.
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Idea to Rejuvenate the Venous System in Terms of Cellular Function
1. Map cell types based on their location in the system.
2. Behavioral analysis: decoding DNA in relation to functionality.
3. Determine the impact on the system's aging.
4. Prioritize cellular interventions
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Good news!
FDA shatters records with 71 new drug approvals, including groundbreaking gene therapies, the first CRISPR-edited treatment, and major advances in Alzheimer’s care. A giant leap for biotech!
Thanks for the share
@Zlatimir1499362
!
The FDA approved 71 new medicines last year, and one of them is an Alzheimer's drug. 🤯
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Long genes, key to aging, become less active and accumulate more damage with age, especially affecting cellular functions like those of the brain. A door opened to new targets for treating aging and Alzheimer’s.
Shared by:
@jordanwillisjvw
🙏
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Hello friends and colleagues. I'm writing to let you know that I have made significant progress on my plan to address aging, and I will update it soon.
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Researchers found that young blood can rejuvenate 🤩 brain vessels in old animals, while old blood accelerates aging in young ones. 😳👏
Thanks to:
@Mangan150
and
@naptimegramps
for the share.
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What? 🙃🤯
** Groundbreaking study ** finds DNA damage and brain inflammation crucial for forming long-term memories!
Share by:
@jordanwillisjvw
🙏
DNA Damage and Inflammation Key to Memory Formation!
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I was reading tonight about biodegradable scaffold with bio 3D printing… Wow, just wow. 🥲
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Happy New Year to all! 🥂🤗
For the new year gift, if you had to choose between immortality as an option, which one would you pick for yourself?
Biological immortality
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Transhumanist (robot)
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None
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I believe the Yamanaka factor could potentially be used in gene therapy on young people to prevent aging.
Yamanaka factor: it can rejuvenate cells by resetting them to a more youthful state.
I agree 🙂
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No 🙃
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Idk, who are you? 🤯
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I would like to see Elon Musk work on solving aging, not for his financial resources, but for his entrepreneurial qualities that make possible the realization of seemingly unattainable, miraculous projects.
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Outside the scope of aging research, but it's such great news: trials are underway to treat multiple sclerosis using immunotherapy! 🤩
The first US trials of engineered cells to treat multiple sclerosis have started recruiting volunteers
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The rejuvenation machine
To insert younger cells multiplied from stem cells preserved through cryotherapy (every year):
AUTOLOGOUS CELL THERAPY using a patient’s own cells. These cells are then reintroduced into the body, it minimize immune rejection.
Old cells killed.
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We will solve aging!! I want to solve aging. 🤩🤩 BIOLOGICAL IMMORTALITY is coming! 🤩😂
Why Manifestation Matters with
@rhondabyrne
@thesecret
🔮
Rhonda Byrne knows that manifestation goes beyond mere wishful thinking, and she's here to reveal the secrets to living your best life.
Ready to transform your life?
This one's for you my friend
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I believe that current gene therapies, for example, with epigenetic resetting or DNA corrections, would work better in young people to prevent aging. I truly think there should be a market for this.
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Advanced Clinical Trials with Mesenchymal Stem Cell Therapies for Osteoarthritis to regenerate cartilage.
Could our own cryopreserved stem cells be used to rejuvenated for 1-6 years, ensuring they stay functional with other cells? 🤔
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My contractor saw me using GPT for real estate renovations and asked how it helps. It’s a tool for tricky questions I face. GPT’s insights have been a game changer.
He knows everything! 😂 I’m like Bob the Builder now 😂
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I mean, could it be use for rejuvenation? By keeping our own stem cells in cryotherapy 1-6 years younger or more? 🤔
Advanced Clinical Trials with Mesenchymal Stem Cell Therapies for Osteoarthritis to regenerate cartilage.
Could our own cryopreserved stem cells be used to rejuvenated for 1-6 years, ensuring they stay functional with other cells? 🤔
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Once, men offered the moon, peak romance. Now, roles reverse! Modern women, excelling at work, aim higher for Valentine’s: not stars, but the secret to eternal life. Who needs the moon when you can offer eternity?
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@davidasinclair
👏👏👏🤩 Question: Rather than rejuvenating or improving the condition of the elderly, have you considered using this type of method to prevent aging in the young? This way, you would likely minimize the risks associated with this promising drug.
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By accident I deleted the post 🤦♀️… 😅:
They used immunotherapy to target and kill senescent cells, which improved metabolic function and fitness in older mice.🤩 That could help to prevent from aging.
Online now! ✨New study shows that
#senolytic
#CARTcell
treatment improves metabolic function & fitness in old mice. A single administration is sufficient and can have long-term preventive effects
@corina_amor_MD
@amor_lab
@LoweLabMSKCC
@MSKCancerCenter
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@TeslaAndDoge
You just said you love USA few days ago, after fifteen years waiting to be an American and your moving. Seems strange to me.
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🔬 Revolution in cellular rejuvenation by Lab GladiChev!
Their innovative chemical process replaces riskier genetic methods, offering safer and more controlled partial reprogramming.
🧵1/9: We are pleased to announce that our manuscript on
#chemicalreprogramming
is now published in the journal eLife:
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The more I work on solving aging, the more I realize how arduous a task it is to rejuvenate an old person. So, I think that someone who has confidence in the future, in the possibility of rejuvenating our cells, should preserve their current cells in cryonics to reuse them later
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I was looking at the photos of David Sinclair and Aubrey de Grey's teams, for whom people talk a lot about their work. I was still surprised to see that these are teams of about 15 to 20 people, and that the most renowned people in the world working on solving aging are around
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I want to clarify that my admiration for David Sinclair’s work is deep and sincere. His contributions to science and the understanding of aging are, in my eyes, remarkable and worthy of admiration. My question regarding rapamycin and the use of induced pluripotent stem cells was
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Exploring how collective intelligence bridges biology across scales, from cells to societies, highlighting its role in solving complex problems and paving the way for advances in regenerative medicine and synthetic bioengineering.
New paper is out -
@DrPTMcMillen
"Collective intelligence: A unifying concept for integrating biology across scales and substrates"
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This is my proposed solution to prevent the shortening of telomeres with the aim of addressing aging.
For a clearer understanding and introduction, I suggest you watch these videos (they are not created by me).
1- Solving aging by preventing telomere shortening - 3 min:
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@ggreenwald
@elonmusk
People trust Elon, I do too. But I think Jack was right when he say it should be a transparent protocol on Twitter for the free speech so no corruption or doubts possible.
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You will never see me shake my hair or do a sexy dance to get likes. Because I want equality, I want the same benefits that men have. The day I see men who are passionate about the field of aging research dancing sexily and shaking sexy for likes, well, maybe then I'll change my
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I think in the short term, we need to achieve "cell immortality" until we find other solutions to live for ever. I truly believe there's a way to solve that in the short term, less than 40 years… 😅
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Yamanaka factors!!! I knew it! OMG!!! That’s amazing!!! 🤩🤩🤩
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Interesting! 🔥
Scientists create novel technique to form human artificial chromosomes!
I got the link from
@jordanwillisjvw
share.
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REJUVENATE YOUR BRAIN 👀
Video games can be a tool for cognitive enhancement! 👏👏
Power up your gray matter with NeuroRacer and Neuroscape's brain-boosting arcade! For a mental pit stop, visit Neuroscape Interventions
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