Ted Price of the Dussor/Price Lab
@UTDPainLab
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Ted Price is Director of the Center for Advanced Pain Studies at UTD. We try to cure pain in all its forms. Ted would prefer to be playing basketball.
Dallas, TX
Joined June 2015
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Pinned Tweet
@dianatavf
and
@sshiers1
paper "Spatial transcriptomics of dorsal root ganglia identifies molecular signatures of human nociceptors" is now online, and we got the cover! Congrats to the whole team. We hope you enjoy the read!
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Let this sink in - "~119 applications from white PIs with scores in the 35th–59th percentile range were funded versus zero applications from Black PIs with scores in the same range."
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Today I am officially taking over as Editor-in-Chief of Neurobiology of Pain - . I am lucky to stand on the shoulders of my mentor and friend Fernando Cervero in taking on this role. I am also lucky to have
@mike_doc_B
joining as Deputy Editor.
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I was surprised this morning when I arrived to an empty room for lab meeting. About two minutes later everyone walked in dressed up as “Ted”. So fun and hilarious. Here we all are later in the afternoon. I’m so lucky to work with these amazing, fun loving scientists.
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Our "pain interactome" paper is out and on the cover of Science Signaling!
congrats
@AndiWangzhou
@CandlerPaige
@MoenoKume
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I didn’t think I’d be lucky enough to have him fall asleep laying on my chest again. If this is the last time I’m gonna document it so I don’t forget. They grow up way too fast!
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Which paper gets your vote for paper of the year in pain? This is my choice. A masterpiece from Rohini Kuner that completely changed the way I think about animal models of pain and how touch becomes pain in neuropathies.
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Just found out that Greg has now been promoted to Full Professor. Greatly deserved promotion for my partner in crime. Y'all know Greg is not on social media, but I promise to send him a telegraph with all your congratulatory tweets.
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Awesome!!! Congrats
@ardemp
and
@DJuliusSF
!!! What a day for sensory and pain neurobiology!!
BREAKING NEWS:
The 2021
#NobelPrize
in Physiology or Medicine has been awarded jointly to David Julius and Ardem Patapoutian “for their discoveries of receptors for temperature and touch.”
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We will be posting a tenure track position in Neuroscience with a focus on Pain and Sensory Neuroscience in the coming days. If you are interested, please feel free to contact me!
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BOOM!! BOOM and BOOM!
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This is such an amazing story of evolutionary neuropharmacology! "Despite their very different, oddly shaped brains, octopuses seem to react to ecstasy just like humans and mice,"
@edyong209
reports
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"Spatial transcriptomics reveals unique molecular fingerprints of human nociceptors"
Our latest work, led by
@dianatavf
and
@sshiers1
, is now online
@biorxiv_neursci
Great collab with
@robgereau
@mike_doc_B
and others
@UTDPainCenter
@UTDResearch
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BOOM! Rohini Kuner has done it again. This is just awesome stuff and drives home the point that we are missing the boat studying events that occur early after injury. Its months later where/when the real action occurs.
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Thank you
@BlackInNeuro
for inspiring us, and for the great shirts. Penelope and I will wear them with pride!!
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Those are all the gloves from
@UTDPainLab
headed to
@Parkland
hospital tomorrow.
@UTDResearch
supports frontline healthcare workers in
#Dallas
. Supply our hospitals!!
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My wife is getting vaccinated today. She is an absolute hero for what she has done throughout this pandemic. I am so glad she will have a safety net now. I am so glad our whole family will have the safety net. The stress has been crushing for all of us, hardest on her.
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Here we go!
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Did you know that another product of pervasive racism is shitty medical care for black people. For instance, black people are less likely to receive any treatment when they are in pain. That is a massive humanitarian failing.
We need to acknowledge these failures and fix them
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My
@BlackInNeuro
shirt and coffee mug came to day and I LOVE them both! We need to order swag to support
@BlackInNeuro
for all of
@UTDPainCenter
to match our
@BlackInNeuro
sponsorship!!
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Just got our first
@10xGenomics
#Xenium
data back on human spinal cord, DRG and nerves and it’s amazing!! Super pumped for building custom panels and profiling gene expression with unparalleled precision.
@UTDResearch
@UTDPainCenter
@dianatavf
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BOOM! "Many of the reasons biomedical scientists cite for choosing not to use female animals in their research are based on false assumptions, poor logic or long-standing myths that are not grounded in fact." -
@AnneZMurphy
@ShanskyLab
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My daughter (6 years old) gave me this lovely navy grenadine tie for my birthday yesterday. She has great taste. Also the big hug and giant smile she gave me this morning when she saw I was wearing it was worth all the money in the world.
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TRPC5 and
#pain
on the cover of
@ScienceTM
this week. The amazing work of
@KateSadlerPhD
,
@FrancieMoehring
,
@sshiers1
and so many others and our first big collaboration with
@Dr_CherylStucky
. Definitely not the last!! more exciting work to come!!
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We have two tenure track jobs available in Department of Neuroscience. Both labs will be in new space in the BSB building and right next to the brand new
@UTDPainCenter
core facility. We have a wonderful Department and amazing students!
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Nav1.7 IHC - lumbar spinal cord - homo sapiens
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Nice substantia gelatinosa! The human spinal cord anatomy art of
@sshiers1
@UTDPainCenter
@UTDResearch
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I want to spend my time writing interesting papers, not endlessly formatting them for journals that make money off of our creativity.
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BOOM major sex differences in THC pharmacokinetics and brain effects.
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BOOM! . This is a huge, clinically transformative finding. Congrats to Alban and team
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It makes sense that such things would happen, but nevertheless, this FREAKING BLOWS MY MIND!
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Human cells and networks of pain in
@NeuroCellPress
today. Thanks to
@willrenthal
@Dr_CherylStucky
@robgereau
@achamess
@lab_seal
@mike_doc_B
@Goldpainlab
and so many others for bringing this collaborative NeuroView to fruition.
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Greg and I have a postdoc position available to work on our expanding human DRG and spinal cord projects. If you are interested in electrophysiology and looking to join a fun, scientifically adventurous group we are the right place for you!
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Way to go Dr.
@JulietMwirigi
!! So happy for you and proud of all you accomplished on your way to earning your PhD!
@NINDSfunding
@UTDResearch
@BBSutdallas
@NINDSDiversity
🎉🎉 Congrats to
@JulietMwirigi
for successfully defending her dissertation today!🎉🎉 We've thoroughly enjoyed your time here and can't wait to see where your scientific career takes you. Congratulations Dr. Juliet Mwirgi 🎉🎉
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BOOM! I think this is a terrific paper from the
@genentech
pain team (many of whom appear to now be at
@23andMe
) on a topic that is near and dear to my heart: nociceptor transcriptomes and their conservation across species.
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This has been the thrill of a lifetime to go from basic research to a molecule that can head toward clinical development. Now onto the next stage! Huge thanks to the
@UTDPainLab
team
@sshiers1
@MoenoKume
@JulietMwirigi
and Ayesha Ahmad.
We are pleased to announce that we have received Phase 2 funding on our U44
@NINDSfunding
to develop MNK inhibitors for neuropathic pain. We will now begin IND-enabling studies. We are excited to continue our journey to improve the treatment of neuropathic pain!
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BOOM! Really impressive discovery of a TrkC+, TH+ set of DRG sensory neurons controlling blood pressure. Losing the neurons causes lethal drop in blood pressure and heart rate variability.
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Wife got jab 2 of Pfizer vaccine at 5AM today and Abuelita, Abuelo, Nina and Grandpa Bill all scheduled for jab 1 in next 48 hrs. I believe the term for my current state is “dead chuffed”!!
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BOOM (First one of 2024)!! Speaking of Nav1.7 and pain: Nav1.7 as a chondrocyte regulator and therapeutic target for osteoarthritis
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Huge congrats to
@JulietMwirigi
and
@Hajira_Elahi
on their doctoral hooding today. What an amazing honor to serve as mentors to these remarkable young scientists.
@UTDPainCenter
@utdneuroscience
@BBSutdallas
@UTDResearch
@NIHendaddiction
@NIH_NINDS
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I have built my career publishing in "society" journals. I am here to tell you it is entirely possible to be very successful with this approach. My focus has been 2 journals -
@JNeuroscience
and
@PAINthejournal
which are the official journals of
@SfNtweets
and
@IASPpain
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3 Tenure Track Positions in BBS Neurobiology are posting soon. We have a great atmosphere and space for neuroscience research and top-notch students. Pain Research will be a big area of emphasis. If you are interested in joining us as our newest faculty members, contact me!
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We are seeking applicants to join our growing Neuroscience Department
@UT_Dallas
. We have two positions this year:
We have a great scientific and academic atmosphere at one of the nation's most diverse universities.
@US_ASP
@BlackInNeuro
@sacnas
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19 years ago today I married the most wonderful woman on earth. Thank you,
@RMarinesPrice
for a beautiful life so far, and to many, many more Oct 26ths!
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I took my 3 year old to get his blood test for the Moderna trial this morning. He was scared and crying, but we sang the ABCs and then when his blood started to come out he yelled "WOW, I like it! I see the antibodies Daddy!!". We all died laughing from the cuteness.
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This paper - - the last paper from
@CandlerPaige
's dissertation, is now accepted for publication
@SfNJournals
Journal of Neuroscience. We added a lot to the paper in revision, including convincing evidence that CGRP acts in CNS to promote pain in females.
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Just got asked what lab I work in. Many interpretations for that question, but I'm going with i found the fountain of youth.
#sfn2019
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BOOM! This paper is awesome -
I am so impressed with the clever experimental design. Answers a question I have wondered about for the longest time, in particular because my OA pain is markedly worse at night.
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Congrats to Dr Ishwarya Sankaranarayanan who just successfully defended her dissertation on ICOS and meteorin mediated resolution of neuropathic pain!!
@ish1789
@UTDResearch
@BBSutdallas
@UTDPainCenter
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First paper in what I hope will be a long collaboration with the one and only
@IsaacMChiu
and the incredibly talented
@sokol_mdphd
on itch and pain mechanisms - The CysLT2R receptor mediates leukotriene C4-driven acute and chronic itch
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Our work on
#CGRP
was featured in the first ever JNeurosci Spotlight Along with a bunch of other awesome papers. Note that 3 of 7 of them are
#pain
papers! Thanks
@JNeuroscience
@SfNJournals
@SfNtweets
for continuing to highlight our work.
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Dissected our first DRGs and spinal cord from an organ donor tonight. Quite an experience. Looking forward to making the most of this amazing resource. Thanks
@BryanCopits
for making it possible.
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Just had our first paper accepted in Journal of Pharmacology and Experimental Therapeutics
#JPET
. I got my PhD in Pharmacology in 2003. Not sure what took so long to hit this milestone, but I am glad we will have a terrific paper in that storied journal.
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Today we are entering the next phase of development for our novel, non-opioid pain therapeutic platform.
@CersciThera
has been acquired by Acadia Pharmaceuticals to take over clinical development. A great partnership to transform pain treatment
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IDK, if the antibodies were Santa Cruz I’d expect them to recognize all variants + flu and six random other viruses and cause a horrid autoimmune reaction that would cause the screen on your gel imager to show a blobby mess every time you walked by.
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Curious about which populations of neurons in the CNS vs. PNS express the greatest diversity of GPCRs, ion channels, or other types of receptors? Us too!! Check out our latest preprint -
@AndiWangzhou
@CandlerPaige
@UTDPainCenter
@UTDResearch
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Our 6 year old gets her first
#Pfizervaccine
on Nov 6 (confirmed appt at CVS) and our 3 year old got enrolled in the
#Moderna
trial. Hallelujah!!
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@pradiptaray
's new work is now online
@biorxiv_neursci
with coauthors
@sshiers1
@dianatavf
@ish1789
@mike_doc_B
To my knowledge, this is the largest transcriptomic study of human neuropathic pain DRGs to date with more than 50 samples analyzed
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Dose two of
#PfizerBioNTech
done. Thank you
@UTSWNews
for running such a great operation. Thank you science! And thank you
@KizzyPhD
and
@NIH
.
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Asking myself again: why do I continue to review for these journals (all the time) when they always reject our papers without review?
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Congrats to
@TonyaPalermo
for taking the Editor in Chief position at Journal of Pain. I cannot think of a better choice for this important position, especially in guiding the direction of the journal as the
@US_ASP
grows.
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BOOM! This blows my mind and suggests that we are studying completely the wrong thing (or at least time point) in mouse neuropathic pain models in male mice, and are just completely clueless on what is going on in female mice
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Got an investigator score of 7 today. Apparently lack leadership and no private sector experience.
Its a lottery, you never know what you are gonna draw so keep writing and submitting the grants. I know it can be beyond frustrating, but eventually your numbers pop up.
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It was great be back at my postdoc alma mater for
@aecrpain
annual pain day. Thanks so much for hosting me
@AKhoutorsky
@JeffreyMogil
and
@rezasharif
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congrats
@superkash
and
@nanopharmNC
on a terrific paper . Dopamine and pain, and the fascinating sex differences that come along with it!! Your wonderful work has us thinking about how descending and ascending dopamine might work together in chronic pain.
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Some great coverage of some outstanding work, including some of ours, in
@nature
today:
@JeffreyMogil
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This paper - - has now been accepted for publication in Brain. Congrats to
@pradiptaray
@sshiers1
@ish1789
@dianatavf
@mike_doc_B
and the rest of the team. Lots of revisions were made so looking forward to the accepted version coming online soon!
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@4ETherapeutics
has now raised 10M for the development of our eIF4E-targeting strategy for the treatment of neuropathic pain and migraine. We are rapidly moving toward the clinic and can’t be more excited about our future!
@NIHFunding
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Amazing plenary from
@YarCarLab
on cell specific roles of amygdala neurons in pain.
@US_ASP
final day is off to a great start.
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Our most excellent paper on dopamine and spike time LTP in lamina I projection neurons is now online
@SfNJournals
. Huge props to Jie Li and Mark Baccei for allowing me to be part of this project and pursuing my dreams of pain LTP mechanisms.
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And we also were featured in
@ScienceMagazine
this week!
New maps of the pain interactome from the
@UTDPainLab
and Ray lab reveal how connections between neurons and dozens of other cell types may shape disease-associated
#chronicpain
.
@AndiWangzhou
@CandlerPaige
#RNAsequencing
#Neuroscience
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Years of effort to develop a topical with as much resveratrol as we could possibly get in there (plus 4% lidocaine) has finally arrived in the mail, nicely wrapped!!
@teds_brain
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I was there for 9-11. Both my PhD and postdoc mentors are on that list, and now I am too. That kinda blows my mind
@daspainbrain
Here you go,
@daspainbrain
. It includes the forthcoming speaker
@UTDPainLab
Number 30 isn't too far down the road. Wonder who that will be!
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The pandemic has nothing to do with permanent residency in the United States. This is about racism, pure and simple. It is evil to the core.
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Thank you
@NIHDirector
for highlighting our paper! Definitely excited about the implications of our work for improved pain therapeutic discovery.
@UTDPainCenter
@UTDResearch
@dianatavf
@sshiers1
@pradiptaray
@robgereau
@achamess
@mike_doc_B
@ish1789
Nociceptors, sensory neurons that create the perception of pain, can help us better understand pain disorders. A study comparing human & animal nociceptors found gender & species dependent differences that may inform future therapies to treat pain
#NIH
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Our human DRG
@10xGenomics
#Visium
spatial sequencing data is now available on our website: . Check it out! Full description is in our biorxiv preprint -
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I had the great pleasure of hooding two amazing scientists today
@ish1789
and Tarjani Shukla. Also great to see
@KunderNikesh
get hooded today.
@UTDResearch
@UTDPainCenter
@BBSutdallas
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@pradiptaray
’s latest work on characterizing transcriptomic changes in the
#DRG
of neuropathic pain patients is now online
@Brain1878
. Lots of major sex differences
#SABV
and new pain targets
@sshiers1
@UTDPainCenter
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Here I come Australia!! Can’t wait to get to Sydney and then onto the
@AusPainSoc
meeting in Canberra!!
@DFWAirport
@UTDResearch
@UTDPainCenter
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First day of the Price house solar roof farm being on and we produced 150kWh and consumed about 100kWh = one giant step toward carbon neutral
#climategoals
#solar
#sunnova
@Sunnova_Solar
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BOOM! This is such an exciting paper on low back pain mechanisms, published today in
@ScienceTM
Congrats to
@SheynLab
and
@laurasstone
and their teams and collaborators on this huge breakthrough.
#hopeforlowbackpain
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We have an exciting position open for a research scientist in our group to focus on analysis of RNA seq and proteomics datasets from our expansive human DRG and spinal cord work. We have a dynamic group
@UTDPainCenter
and incredible resources!
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Department of Biological Sciences
@UT_Dallas
is hiring tenure track faculty - .
@UTDResearch
is a great place to work with dynamic research in biology, bioengineering and neuroscience.
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BOOM!! This paper is so fascinating. Lots of new insight on loss of function in TRPV1 in humans with some interesting effects on other TRP-channel mediated effects.
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Remembering Stephen McMahon, a great electrophysiologist, innovator and mentor beautiful tribute from
@denk_lab
to the memory of Mac.
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#USASP
in Seattle was one of the best meetings I have been to in a long time. The quality of the trainee talks and posters was just off the charts. More basic scientists in pain need to get involved in this society. It is doing great work and running a great meeting.
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human spinal cord and associated nerves stained with two antibodies (
@sshiers1
and my secret). dorsal is down.
#neuroscience
is so beautiful.
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