The Lancet Neurology is the leading journal in clinical neurology. We publish articles and reviews that advocate change in, or illuminate, clinical practice.
NEW
#COVID19
: Guillain-Barré syndrome associated with SARS-CoV-2 infection: causality or coincidence?
In their Correspondence, Hua Zhao and colleasgues higlight the need to consider potential neurological symptoms of SARS-CoV-2 infection
Celebrating neuroscience through art: Our covers throughout 2021 will illustrate the extraordinary work of The Cajal Embroidery Project
Read more about Cajal's legacy
Globally,
#stroke
is the second leading cause of death. The GBD 2019 Stroke collaborators call for urgent implementation of effective primary prevention strategies to curb the increasing burden of stroke:
The Boston criteria are used worldwide for the in-vivo diagnosis of CAA but have not been updated since 2010. In an Article,
@a_charidimou
and colleagues present updated criteria across the full spectrum of clinical CAA presentations. Read more at:
“Migraine remains one of the most stigmatised, underfunded, and underrecognised medical conditions”. Read our letter highlighting the
@wfneurology
campaign this
#worldbrainday
to reveal the painful truth about
#migraine
In their Review, Professor Nicolaas Bohnen and colleagues provide an update on cholinergic systems and changes in Parkinson's disease and isolated REM sleep behaviour disorder, a Parkinson's disease prodrome.
NEW ISSUE: Read the latest content on chronic cluster headache, myasthenia gravis, cognitive impariment, Parkinson's disease, mitochondrial disease, and more
ONLINE FIRST: Weaver and colleagues identify infarct locations most strongly predictive of post stroke cognitive impairment and use this information to develop a prediction model. Read more at:
NEW ISSUE: Read the latest content on Parkinson's disease, seizure prevention in ICH, prognostic biomarkers for TBI, Duchenne muscular dystrophy, MS, tuberous sclerosis complex, and more at:
Our August issue is available online now, including original research on biomarkers in patients with Down syndrome and Alzheimer's disease, outcomes after TBI, and virus-specific T cells for progressive multifocal leukoencephalopathy
Physicians should warn their patients of the illusions of pseudomedicine and its risks. Mounting evidence shows that low-cost lifestyle changes are the best interventions to improve brain health and prevent cognitive decline.
NEW! Just published Online First, a phase 3 randomised trial of tenecteplase vs alteplase for acute ischaemic stroke in Norway (NOR-TEST 2 part A)
#ESOC2022
NEW ISSUE: Read the latest content on the global burden of neurological disorders,
#migraine
, Duchenne muscular dystrophy,
#stroke
prevention, dysphagia after stroke, and more at
Conditions that affect the nervous system are affecting the lives of increasing numbers of people. Read more in our new paper on the global burden of nervous system disorders, from
@IHME_UW
and
@WHO
Our September issue is available online now, with content on COVID-19, multiple sclerosis, acute ischaemic stroke, Alzheimer's disease and frontotemporal lobar degeneration, and myelin-oligodendrocyte glycoprotein antibody-associated disease
NEW ISSUE: Read the latest content on insomnia disorder, autosomal dominant Alzheimer's disease, frailty and TBI, autoimmune neuromuscular junction disorders, and more at
Just published Online, The Lancet Neurology Commission on traumatic brain injury
#TBI
Following on from our 2017 TBI Commission, this latest Commission highlights progress and challenges in prevention, clinical care, and research
Stroke is a major cause of death and disability, and its global impact is getting worse. However, it is a highly preventable and treatable condition, meaning the associated health and economic impacts can be substantially reduced.
ONLINE FIRST: Charlotte Teunissen and colleagues review the highly dynamic and accelerating field of blood-based biomarkers for Alzheimer's disease:
@CharlotteTeuni1
NEW ISSUE: Read the latest content on
#MultipleSclerosis
,
#Migraine
, myotonic dystrophy type 1, cerebral palsy,
#Autism
, carpal tunnel syndrome, MOGAD, and more at
NEW ISSUE: Read the latest content on blood pressure management after endovascular therapy; Guillain-Barré syndrome; gene therapy for spinal muscular atrophy;
cerebral microbleeds and prediction of intracranial haemorrhage; and more at
NEW ONLINE: In their Personal View, Brenda Banwell and colleagues propose diagnostic criteria for myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD)
NEW ISSUE: Read the latest content, including research on asymptomatic carotid stenosis and risk of stroke, detection of prodromal α-synucleinopathies, and new insights into atypical Alzheimer's disease
In a Personal View, Olivier Rascol, Margherita Fabbri, and Werner Poewe discuss the use of amantadine in
#Parkinson
's disease and other movement disorders
NEW ISSUE: Read the latest content on Duchenne muscular dystrophy, inclusion body myositis, multiple sclerosis, acute brain injury, migraine, stroke, and more at:
NEW ISSUE: Read the latest content on unruptured brain arteriovenous malformations, cognitive impairment in type 2 diabetes, Parkinson's disease, stroke, and brain injury after cardiac arrest
ONLINE FIRST: Read the TRUTH trial, comparing two strategies for the treatment of patients with acute ischaemic stroke and increased blood pressure precluding intravenous thrombolysis:
Presented at
#ESOC2024
NEW, published Online First and free to access after registration, a Personal View by Viktor Jirsa and colleagues of the use of personalised virtual brain models in epilepsy.
@HumanBrainProj
@thevirtualbrain
Now online from the
@IHME_UW
series on global, regional & national burden of neurological diseases: prevalence, mortality, and disability associated with Alzheimer’s disease and other dementias
#GBDStudy
#openaccess
In their Personal View, Linda Al-Hassany, Peter Goadsby, A H Jan Danser, and Antoinette MaassenVanDenBrink discuss how to optimise migraine treatment for the patient by considering pharmacological aspects of the drugs.
NEW ISSUE: Read the latest content on narcolepsy in children, ischaemic stroke, basilar artery occlusion, EBV and MS, and family planning considerations in MS at:
"Differences exist between Parkinson's disease in the Western Pacific Region and in Europe and North America that might provide important insights into our understanding of the disease."
Read more at:
#wpc2019
NEW ISSUE: Read the latest content on
#stroke
,
#Parkinsonsdisease
, spinal muscular atrophy, optic neuritis, multiple sclerosis, and social determinants of neurological health at:
In our May issue, two Articles report phase 3 data for new drugs for myasthenia gravis. In a linked Comment, Jan Verschuuren discusses how these two new drugs target this neuromuscular disorder, and how they fit within a growing therapeutic landscape.
We’ve teamed up with
@TheLancetPsych
to organise a meeting bringing together psychiatry and neurology. Come to Barcelona, Nov 15–17 for the Lancet Summit: Inflammation and Immunity in Disorders of the Brain and Mind.
In their Review, Daniel Weintraub and colleagues discuss developments in our inderstanding of the neuropsychiatry of Parkinson's disease, and outline the key unanswered questions and challenges facing this field:
NEW ISSUE: Read the latest content on
#Downsyndrome
, spinal muscular atrophy, idiopathic hypersomnia,
#AlzheimersDisease
,
#Parkinson
disease, and
#stroke
, as well as our annual Round-up of research across disciplines over the past year
Online now! Global, regional, and national burden of Parkinson’s disease: the first paper in a series from
@IHME_UW
on individual neurological diseases:
#GBDStudy
#Parkinsons
#openaccess
Expert commentary:
"Collaboration to improve our knowledge of COVID-19, including its long-term neurological manifestations, must continue to be a high priority"
Read more at:
NEW ONLINE:
@karaannjohnson
,
@MichaelOkun
, and colleagues review the latest evidence on clinical features, diagnosis, genetics, pathophysiology, and treatment of Tourette syndrome
The SANAD II study of the effectiveness and cost-effectiveness of valproate versus levetiracetam for newly diagnosed generalised and unclassifiable epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial
Today is
#WorldStrokeDay
. Visit our
#stroke
collection for the latest original research, reviews, expert commentary, podcasts and more from across the Lancet family of journals!
#UpAgainAfterStroke
NEW ISSUE: Read the latest content on
#stroke
, functional neurological disorders, sexual dysfunction in patients with neurological disorders, CDKL5 deficiency disorder, and more at:
Published Online for
#WSC2023
, first results from the COCROACH individual participant data meta-analysis looking at the effects of oral anticoagulation in people with atrial fibrillation after spontaneous intracranial haemorrhage
NEW ISSUE: Read the latest content on intensive versus standard blood pressure control and cognitive function; neuropathological alterations in patients with COVID-19; genetic modifiers of clinical age of onset in Huntington’s disease; and more at:
NEW ISSUE: Read the latest content on asymptomatic carotid artery stenosis, stroke, anti-NMDA receptor encephalitis, migraine, diabetic peripheral neuropathy, sleep disorders, and more at:
The Lancet Summit 2018—Inflammation and Immunity in Disorders of the Brain and Mind
Hosted by
@TheLancetNeuro
and
@TheLancetPsych
, November 15-17, in Barcelona, Spain
Register your interest to attend and submit your abstract by May 18:
#thelancetsummit
Online now! Review of the clinical presentation of stroke-associated cardiac alterations; are these as distinct "stroke–heart syndrome"?
#stroke
#WorldStrokeDay
NEW ONLINE On
#WorldParkinsonsDay
, an Article by
@em_ka_gu
,
@MatthewJFarrer
, and colleagues reports a novel genetic risk factor for Parkinson's disease in the RAB32 gene (Ser71Arg, 213C>G), which was identified in multiple ethnic groups
"The diagnosis of Parkinson's disease has profound implications for patients and their families, and despite important advances, it remains a challenge."
Eduardo Tolosa and colleagues discuss these challenges in their Review:
Call for Posters:
#TheLancetSummit
: Presymptomatic Prevention and Treatment of Neurodegenerative Diseases, Dec 14-16, 2021. Submit your abstracts by Aug 13. . Organised by
@TheLancet
and
@TheLancetNeuro
.
This year marks 20 years of TheLancetNeuro. Each issue will celebrate progress in the field since the journal's launch. In our Jan issue, Benjamin Kanter, Christine Lykken, Edvard Moser, and May-Britt Moser reflect on neuroscience in the 21st century:
In our anniversary issue, we commemorate two decades of progress in neurology. We’d encourage you to explore five landmark papers from our history, and read our Editorial here:
Online now! Review on mechanisms of action for the medium-chain triglyceride
#ketogenic
diet in
#epilepsy
, and other neurological or metabolic disorders.