Reminder: H5N1 is just steadily building - different animals, human infections, eggs getting expensive. Doesn't have to be a black box. Can track here:

It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS, indeterminate dendritic cell histiocytosis or other (non-LCH) histiocytic sarcomas cases. I'm trying to understand non-surgical chemo and targeted therapy options, new pathology markers to better diagnose subtypes/treatments, and any data on progression in pediatric patients. Please feel free to share – I’m trying to cast a wide net due to the rarity of this condition and how little is known. People can contact me directly at my first name (as written in my profile) at

I have some bad news and some good news. Bad: Function Health's “100+ lab tests for $500/year” is classic marketing. Good: You can do better. What's the bad news? 𝟭. 𝗜𝗻𝗳𝗹𝗮𝘁𝗲𝗱 𝘁𝗲𝘀𝘁𝘀 𝗻𝘂𝗺𝗯𝗲𝗿𝘀 The true number of tests is much lower. Take a look at the “Heart” Section: ( Function Health lists 15 tests. In reality, these are just five distinct tests: 𝗦𝘁𝗮𝗻𝗱𝗮𝗿𝗱 𝗟𝗶𝗽𝗶𝗱 𝗣𝗿𝗼𝗳𝗶𝗹𝗲: This panel provides values for total cholesterol, HDL, and triglycerides measured via enzymatic reactions. Other numbers like LDL, non-HDL cholesterol, and the cholesterol/HDL ratio aren’t separate tests; they’re calculated from the measured values. 𝗔𝗱𝘃𝗮𝗻𝗰𝗲𝗱 𝗟𝗶𝗽𝗶𝗱 𝗣𝗿𝗼𝗳𝗶𝗹𝗲: This single test (often performed via NMR) gives detailed information such as HDL Large, LDL Particle Number, LDL Peak Size, LDL Medium, LDL Small, and LDL Pattern. Again, while multiple values are reported, they come from one comprehensive test. 𝗟𝗶𝗽𝗼𝗽𝗿𝗼𝘁𝗲𝗶𝗻 (𝗮), 𝗔𝗽𝗼𝗕, 𝗮𝗻𝗱 𝗵𝘀𝗖𝗥𝗣: These are indeed separate tests, each providing unique insights into cardiovascular risk. Similarly, the cancer category lists PSA as if it were three separate tests—PSA total, free PSA, and the percentage of free PSA—but PSA is actually a single test? If you bought a car, I imagine you wouldn’t have to say that the wheels, steering, seats were included? 𝟮. 𝗥𝗲𝗽𝗲𝘁𝗶𝘁𝗶𝗼𝗻𝘀 𝗔𝗰𝗿𝗼𝘀𝘀 𝗦𝗲𝗰𝘁𝗶𝗼𝗻𝘀: Some tests appear in multiple sections. For instance: Calcium is listed three times (once under nutrients, once under kidneys, and again under electrolytes), Chloride, hsCRP, and Sodium appear twice. Ok, now the good part. 𝗖𝗮𝗻 𝘆𝗼𝘂 𝗱𝗼 𝗯𝗲𝘁𝘁𝗲𝗿 𝘁𝗵𝗮𝗻 𝗙𝘂𝗻𝗰𝘁𝗶𝗼𝗻 𝗛𝗲𝗮𝗹𝘁𝗵 𝗼𝗻 𝗽𝗿𝗶𝗰𝗲? YES, YOU CAN! Function Health suggests that the tests included in their membership might cost more than $15,000 elsewhere. This is not true. If you were to purchase these tests directly—for example, online from a provider like Quest Diagnostics—the cost would be closer to about $1,200 (maybe even lower). So doesn't it mean Function Health's offering has a clear value proposition? Let me blow your mind. There are 60 tests that Function Health says they will run twice a year for you. Guess how much this battery of 60 tests would cost you if you were a DPC clinic instead of an individual customer? $𝟮𝟱. Yes, you read that right. So here's the takeaway: get a good DPC clinic with a physician you like and have them order these tests for you. You will save money. You will have all the data you really need on your health. You will be supporting the DPC model and enabling more clinicians to break away from a system that is not working.

my first (and possibly only) substack post! I write about why everyone in my lab is cringe and sucks. link in replies

🚨🌊🪸🧬🐠📹✨ A week ago, we assisted with setting up and maintaining Zoe's Living Sculpture ethernet cable in the water as part of the Cozumel Coral Conservatory (CozCC). A big shoutout to David Lehrian (Lead Tech of Zoe), @skualo_751 (coral marine biologist), and @misssnailpail (socio-ecological artist & coral reef practitioner) for their contributions to the Cozumel Coral Conservatory / Zoe Living Sea Sculpture. Special thanks also to @celiicm, a dedicated volunteer at @cozumelcoral! 🔗 ZOE Story: 📹 Today's Live Stream of ZOE 🧬🪸: 🌊 CozCC: A huge thanks as well to the Cozumel Coral Conservatory (CozCC) partners: @cozumelcoral, @SandDollarSport, @WaveofChange, @CIMAC_COZUMEL, @l_arrecifes - @Cinvestav, and @LivingSeaSculpt —without them, this wouldn’t be possible! Some other social media posts of our partners: 1. 2.

DeSci AI Agent Hackathon incoming... Participate online! Cool Prizes. Many many winners. Sign up in next tweet.

Why do all the AI logos look like butt holes?