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MetaMorpheus @metamorpheus.bsky.social Profile
MetaMorpheus @metamorpheus.bsky.social

@Smith_Chem_Wisc

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Lloyd Smith Research Group Committed to free, open-source software for proteomics in both Windows and Linux. And you won't need a comp sci degree to use it!!

UW-Madison
Joined October 2018
Don't wanna be here? Send us removal request.
@Smith_Chem_Wisc
MetaMorpheus @metamorpheus.bsky.social
3 months
@J_my_sci This is fantastic news. Kudos to you and your team
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@Smith_Chem_Wisc
MetaMorpheus @metamorpheus.bsky.social
3 months
RT @byu_sam: #teamMassSpec. I’m so excited to share our work on improving quantification through FDR controlled peptide identity transfer (…
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@Smith_Chem_Wisc
MetaMorpheus @metamorpheus.bsky.social
3 months
Improved detection of differentially abundant proteins through FDR-control of peptide-identity-propagation
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@Smith_Chem_Wisc
MetaMorpheus @metamorpheus.bsky.social
3 months
@uiowachem Couldn't happen to a nicer guy!
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@Smith_Chem_Wisc
MetaMorpheus @metamorpheus.bsky.social
3 months
RT @scicommlab: Happy Native American Heritage Month! Celebrate and share with @JudithSimcox's inspiring journey:
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@Smith_Chem_Wisc
MetaMorpheus @metamorpheus.bsky.social
3 months
@J_my_sci Venn diagram showing the overlap between people who care about the number of replicates and the people that are performing experiments.
Tweet media one
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@Smith_Chem_Wisc
MetaMorpheus @metamorpheus.bsky.social
3 months
@davidjglassMD For those that know, no words are necessary. For those that don't, no words are sufficient. I'm like Don Quixote trying to get anyone to increase their N.
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@Smith_Chem_Wisc
MetaMorpheus @metamorpheus.bsky.social
3 months
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@Smith_Chem_Wisc
MetaMorpheus @metamorpheus.bsky.social
4 months
RT @wfondrie: (2/2) 👉 Papers without code are just advertisements. 👉 #OpenSource is only good for science. 👉 Proprietary software has a pla…
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@Smith_Chem_Wisc
MetaMorpheus @metamorpheus.bsky.social
4 months
RT @ypriverol: I respect all in #OpenSource discussions in #proteomics. We share challenges but face different constraints. My hope is that…
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@Smith_Chem_Wisc
MetaMorpheus @metamorpheus.bsky.social
4 months
@michaellazear @NIH @NIGMS @NIGMSgenes Ward. I think you are being a little hard on the Beaver.
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@Smith_Chem_Wisc
MetaMorpheus @metamorpheus.bsky.social
4 months
@michaellazear @nesvilab @chrashwood @fcyucn @animesh1977 @GeorgWa @ucdmrt @maxquant @github @JimmyEng And I respect your point of view. It is one that I have shared at points in my life. But, for me, at present, it is no longer the case.
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@Smith_Chem_Wisc
MetaMorpheus @metamorpheus.bsky.social
4 months
@nesvilab @chrashwood @michaellazear @fcyucn @animesh1977 @GeorgWa @ucdmrt @maxquant @github @JimmyEng The choice to make your source open or to charge money is complicated and personal. I wouldn't presume to judge someone's choice. I totally respect the Nesvizhskii team's decision. Even without their source code, we have benefited greatly from them and we will always be grateful
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@Smith_Chem_Wisc
MetaMorpheus @metamorpheus.bsky.social
4 months
@ClarkNano Were I the referee I would be grateful that I had two lines less to read.
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@Smith_Chem_Wisc
MetaMorpheus @metamorpheus.bsky.social
4 months
What is the appropriate way to compute FDR when you have a low number of peptide identifications. <50 or <100 or <500. The standard target/decoy formula works well for a few 1000 ids but is harsh for a few dozen. Side note, I don't really know if FDR matters for low numbers...LOL
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@Smith_Chem_Wisc
MetaMorpheus @metamorpheus.bsky.social
5 months
@byu_sam I feel like I have been truly seen.
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@Smith_Chem_Wisc
MetaMorpheus @metamorpheus.bsky.social
5 months
@J_my_sci can you remind me who (maybe you?) reported detectability?
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@Smith_Chem_Wisc
MetaMorpheus @metamorpheus.bsky.social
5 months
RT @JProteomeRes: 🔓 #OpenAccess + Most Read in the past 30 days: "Are We There Yet? Assessing the Readiness of Single-Cell Proteomics to An…
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@Smith_Chem_Wisc
MetaMorpheus @metamorpheus.bsky.social
6 months
@J_my_sci @byu_sam Or maybe Sam's parents were just playing a mean joke on him.....
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