Nano Bio Optics Lab (Yoav Shechtman)
@ShechtmanLab
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We develop microscopy methods to observe life on the nanoscale
Israel
Joined December 2015
Gen-AI producing fancy data augmentation for Super-resolution microscopy! Great work @AlonSaguy and team! @HenriquesLab @HeilemannLab
If robots could dream of microtubules, how would they look like? An amazing story by Alon Saguy, @ShechtmanLab and colleagues. Proud we could contribute to it
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Great work @yevgenin @DanielleSapir et al.!
Thrilled to share OM2Seq! We applied #AI methods to #Genomics, improving the speed and accuracy of optical genome mapping for fast diagnostics of diseases. @DanielleSapir, Tahir Detinis Zur, Nir Weinberger, @boknilev, @hagenom, @ShechtmanLab 🔬🚀
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We used the Incucyte system by @SartoriusGlobal. All this and more in our latest paper: Big thanks and congrats to all co-authors and collaborators: Nadav, @EliasNehme9 Noam, Ilana, Reut, Boris, Paul, @AlaloufOnit , @SartoriusGlobal !
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@Ella_Maru @naturemethods @AlonSaguy @AlaloufOnit @HeilemannLab Thanks! Re simultaneous processes - there will be a complexity-performance tradeoff that would be interesting to check (TBD). Of course if the processes are labeled orthogonally (e.g. different colors) then each one will just be solved separately.
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More info in the preprint: …, where we demonstrate the use-case of generating training data for CARE (by @martweig et al.) 3/4
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This is a very ongoing project, with many open questions: what are the performance limits? How much can we really gain beyond the information in the training data? and of course: what would be the best uses of something like this in super-resolution microscopy? 4/4
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@christlet Interesting. Do you also get blinking-pairs mistaken for a vertically-elongated PSF (high Z)? I would expect to see a similar number of those.
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Great work by @yevgenin applying information theory to optical genome mapping, with implications to optimal label design
New #preprint! TLDR: Applying #informationtheory on #OpticalGenomeMapping🧬, one can choose pattern-labelling #enzymes giving #10x accuracy! 🤯 To illustrate, let’s play a game! ⬇️ (1/4)
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