Professor & Chairman of Medicine, Baylor College of Medicine, Gastroenterologist and Hepatologist. past president Amer Gastro Association. opinions are mine
Just rotated off the
@AmerGastroAssn
Presidency and what a year it was! Honored beyond words to have served in that role. Great organization and staff. Good future under Dr Omary.
Pic with a bust of Michael DeBakey; where do you think? No not Houston but Marjayoun a little village in south Lebanon (beautiful country) where DeBakey family hails from
@bcmhouston
@BCMDeptMedicine
Having dinner on a rooftop restaurant in Istanbul and this is the stunning view: Ahmet Sultan (Blue Mosque) and Hagia Sofia mosque. Layers of civilisations and beauty
View a farewell video from Hashem El-Serag, AGA past president, as he reflects on a successful year. Thank you
@SeragHashem
for your service to AGA members and commitment to the field!
#GITwitter
It was my pleasure/honor to write this piece introducing my friend
@InadomiJ
as
@AmerGastroAssn
president. Great guy too! Our New President—John M. Inadomi, MD, AGAF
Important study for a common clinical scenario
Hepatic steatosis with persistently normal ALT have lower risk for cirrhosis/HCC c/w with steatosis and elevated ALT
Risk of Cirrhosis and HCC in Patients with NAFLD and Normal Liver Enzymes. - PubMed - NCBI
An amazing achievement
@KanwalFasiha
@AmerGastroAssn
reflects the great work of the editors (esp Dr Kanwal) and staff. CGH now has the highest impact of any US based general clinical GI journal. Congratulations
Great news! Clinical Gastroenterology and Hepatology, AGA’s clinically focused journal, reached a record-high 2020 Impact Factor of 11.382, pulling ahead as the field’s top exclusively clinically oriented journal!
@SeragHashem
@KanwalFasiha
got renewed
@NIHFunding
T32 training grant. 15 years producing physician scientists
-trained in the content areas, methods in GI
-mastered research skills, including project design, planning, funding, execution, management, and reporting.
Our recent work.
1. Each additional metabolic trait increased the risk of cirrhosis and HCC in NAFLD.
2. Diabetes conferred the highest risk of HCC.
Effect of Metabolic Traits on the Risk of Cirrhosis and HCC in Non‐alcoholic Fatty Liver Disease
NEW GUIDELINE ALERT: AGA Clinical Practice Guidelines on Management of Gastric Intestinal Metaplasia just posted as
@AGA_Gastro
Article in Press (login req'd) - will be public next week. First look:
@samirguptaGI
@SeragHashem
@SultanShazi0314
What are the chances! I have had 2 published papers each with TWO of this years Nobel prize winners; both papers on hepatitis B (not C!) A research agenda for curing chronic hepatitis B virus infection.
We are excited to launch Hepatocellular Carcinoma Early Detection Screening (HES) for public commentary. 5 years in the making ! Easy to use risk calculator. Please send me your feedback
@AASLDtweets
@ILCAnews
@AmerGastroAssn
An unprecedented at least in recent memory call from leading medial journal for a change in the country leadership. Read and judge. Dying in a Leadership Vacuum | NEJM
After COVID-19 is controlled, there will still be NAFLD and unlike other ch liver diseases, progression is W>M. Our recent paper: Women have Lower Risk of NAFLD but Higher Risk of Progression vs Men: A Systematic Review and Meta-analysis. - PubMed - NCBI
Finally our validation paper of HES algorithm for HCC surveillance. Try it out . @
@AmerGastroAssn
@AASLDtweets
Validation of the Updated Hepatocellular Carcinoma Early Detection Screening Algorithm in a Community-based Cohort …
Metabolic (dysfunction)-associated fatty liver disease in individuals of normal weight
We review epidemiological data on this group of patients and consider overall metabolic health and adaptation as a framework to best explain the pathogenesis of MAFLD
>Risk of cirrhosis increased 17 folds in individuals with obesity, excessive drinking and who were homozygous for PNPLA3 I148M
>Risk of HCC increased 30 times in individuals with 3 risk factors
Check: Synergistic Associations of PNPLA3, Alcohol,Obesity
Non COVID related ! The new face of cirrhosis. Very little active HCV or HBV. Mostly alcohol and NAFLD Risk Factors for Cirrhosis in Contemporary Hepatology Practices-Findings from Texas Hepatocellular Carcinoma Consortium Cohort. - PubMed - NCBI
Happy to share this timely in depth review
@AASLDtweets
@AmerGastroAssn
@bcm_gihep
Nonalcoholic steatohepatitis-related hepatocellular carcinoma: pathogenesis and treatment
Important clinical guidance for diagnosis, risk stratification and management of NAFLD
@AmerGastroAssn
geared toward PCP. VALIDATION NEEDED
Clinical Care Pathway for the Risk Stratification and Management of Patients With Nonalcoholic Fatty Liver Disease
Check out this recent GERD review; took a couple of years to complete and was a pleasure to work with great colleagues
@AmerGastroAssn
@nature_review
Gastro-oesophageal reflux disease
Our latest paper lead
@NatYamini
shows that HCC occurs in 0.4%/y in PBC overall and 1.5%/y in PBC cirrhosis. Male gender was also a risk factor. Incidence of Hepatocellular Carcinoma in Primary Biliary Cholangitis: A Systematic Review and Meta-Analysis
Congratulations to Dr. Fasiha Kanwal on receiving a Department of Defense grant for her work on the risk of hepatocellular cancer in individuals who were cured of hepatitis C with direct-acting antiviral agents.
Dr. Fasiha Kanwal’s work
@IQuEStHouston
in cirrhosis quality measures on hepatocellular carcinoma screening led to implementation of a performance measure as part of CMS pay for performance program and America’s Health Insurance Plans.
#VAResearch
#VAResearchWeek
#HCCscreening
Yesterday i was honored to give the Anil Rustgi lectureship at U Penn. he left a legacy of a deep talented GI division
@Penn
@AmerGastroAssn
#alwayssunny
NCAA and Hepatology University of Kansas will play UNC for NCAA Men’s National Championship tonight
last time these teams played for the National Championship was 1957, starting guard of that 1957 Jayhawk team is none other than our Hepatology colleague, Blaine Hollinger
Congratulations to Dr. Hashem El-Serag on his new appointment as Vice President of BCM's Learning Health System Initiative!
As a national leader in this area, Dr. El-Serag will lead vision development & work with leaders to achieve goals.
Congratulations,
@SeragHashem
!
Our recent paper: Nearly half of veterans with cirrhosis have delays in diagnosis of HCC of 60 days or more after a red flag
@HardeepSinghMD
@AmerGastroAssn
Factors Associated With Delay of Diagnosis of HCC in Patients with Cirrhosis
@KanwalFasiha
giving a talk on
#nafld
and hepatocellular carcinoma . The first annual symposium for TeCH (Texas Collaborative Center for HCC)
@CPRITTexas
. >120 attendees !
NAFLD is associated with CAD, cardiac remodeling, aortic valve remodeling, mitral annulus valve calcifications,cardiomyopathy and stroke
Cause or epiphenoma?
Mechanisms?
Read more below
NAFLD in Cardiovascular Diseases: A Contributor or Comorbidity?
Our recent paper. # Texas has the highest HCC rates in US # border counties have esp high rates # Hispanic pop at highest risk. Texas Has the Highest Hepatocellular Carcinoma Incidence Rates in the USA. - PubMed - NCBI
(1/4) Thank you for your patience as we evaluated the status of
#DDW2020
in light of the rapidly changing
#coronavirus
pandemic. Read our full cancellation announcement:
❗ Just published in
@AGA_Gastro
: AGA Rapid Recommendations for Gastrointestinal Procedures During the
#COVID19
Pandemic. Provides detailed guidance on
#PPE
& triaging procedures.
Most patients with newly diagnosed gastric cancer had ≥ 2 known risk factors for gastric cancer but never received prior screening endoscopy. Among the few with known prior preneoplastic lesions, endoscopic surveillance was not consistently performed.
In pts with NAFLD longitudinal changes in non-invasive tests for liver fibrosis such as FIB-4 was strongly associated with progression to cirrhosis and HCC
@aasld
@AmerGastroAssn
@GCholankeril
Excited to see our recommendations published and look forward to implementation
Prevention of HCC. White Paper of the Texas Collaborative Center for HCC
@CPRITTexas
Excited to work with
@JagChhatwal
who will be leading a dedicated project in this P01 to model the natural history and the cost effectiveness or preventive and diagnostic measures of HCC in NAFLD and
@KanwalFasiha
who will examine HCC chemoprevention in NAFLD
Packed room of internal medicine interest group . An event at Baylor Dept of medicine where aspiring med students meet with faculty and fellows from all of medicine specialities over Fadi’s Mediterranean grill dinner. Building a strong pipeline
@BCMDeptMedicine
Happy to share our recent paper; complicated association between obesity parameters and gastric intestinal metaplasia
@AGA_CGH
@AmerGastroAssn
Inverse association between gluteofemoral obesity and risk of non-cardia gastric intestinal metaplasia
As a result of decreasing incidence HCC among males aged <50, HCC is changing to a less male predominance
@aasld
Sex and Race Disparities in the Incidence of HCC in the United States Examined Through Age-Period-Cohort Analysis. - PubMed - NCBI
Our recent paper. Only curative intent (transplant, resection) predict >5 yr survival among pts with HCC. a sobering reminder
@AASLDtweets
@ILCAnews
Predictors of 5 yr survival among patients with hepatocellular carcinoma in the US: an analysis of …
Dunning-Kruger effect occurs when a person's lack of knowledge and skills in a certain area cause them to overestimate their own competence. this effect also causes those who excel in a given area to underestimate their relative abilities as well