J. Andrew Pospisilik
@PospisilikJ
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Love life, love science, think, share, create, listen, feel...do good.
Joined January 2020
🚨 Great alternatives to BioRender are now available!! 📢 @NIAIDNews offers a collection of public figures and icons for everyone to use. Check it out at https://t.co/cZFQAf5nTz
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If you are interested in a faculty position in the heart of metabolism, at one of strongest and most supportive institutes focused on metabolism, epigenetics, neurodegeneration and more, VAI is recruiting at all levels!
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Doing good science is 90% finding a science buddy to constantly talk to about the project.
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Here it is! A huge milestone in neuroscience – the complete connectome of the fly brain from the FlyWire team (@FlyWireNews). In this special issue, we have 9 research articles. I’ll try to summarize them in a couple threads starting here 🧵
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Immune cells have a metabolic backup plan for accessing their anti-cancer playbook, according to new research from @DrRGJonesLab and collaborators published in @JExpMed:
vai.org
Read about Immune cells have a metabolic backup plan for accessing their anti-cancer playbook on Van Andel Institute – Stay updated on the latest research and groundbreaking discoveries in science...
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Since @Nature asked for comments on their editorial attempting to justify (and failing miserably) their decision to publish a whitepaper as a peer-reviewed article, I sent them my thoughts. Attached.
@Nature it's really not that complicated. There is no need at all for double standards. You can support whitepapers / adverts. Just tag them explicitly as a different category & don't call them "peer reviewed" cuz it's almost impossible to verify comp. results without models/code
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How do chromatin modifications quantitatively impact gene expression? How do sequence variants or combinatorial marks influence relationships? We developed a modular #EpigenomeEditing toolkit to systematically test these Q, published today 🧵… https://t.co/2p4W0J50Oc
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Very cool single embryo combined transcriptomic and metabolomics Methodology from the @lempradllab lempradllab. Open the door to exploring definitive coupling between metabolic and epigenetic programs.
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Excited to be co-organizing the 2024 @VAInstitute Epigenetics Symposium July 8-10. This year's theme will be 'Cancer Epigenetics' with keynote lectures from Drs. @helin_kristian and Steve Baylin.
vai.org
Join us for VAI Epigenetics Symposium at Van Andel Institute Stay informed about exciting upcoming events and activities.
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PhD students: it’s a waste to just try to impress your committee at the meeting. Bring them problems, ask for suggestions, and generally think of it as a session in which new ideas can emerge.
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Outstanding discovery science (@SchuhLab) and art (@munafomarzia). More broadly, cytoplasmic lattices in oocytes being used as backpacks for proteins with future functions adds to the question… What is *full* nature of biological inheritance?
In the latest issue of @CellCellPress we show that mammalian oocytes store proteins for the early embryo on cytoplasmic lattices. Imagine the cytoplasm as a pantry with proteins stored on shelves made by cytoplasmic lattices! Thanks to @munafomarzia for the beautiful #SciArt!
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🚨New Preprint🚨 In this study, we set out to determine how the de novo DNA methylation program impacts the 3D cis regulatory landscape. Comments welcome! Here's a thread detailing our study's key findings (1/12)
biorxiv.org
During mammalian embryogenesis, both the 5-cytosine DNA methylation (5meC) landscape and three-dimensional (3D) chromatin architecture are profoundly remodeled during a process known as “epigenetic...
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This month we are highlighting recent research relevant to #diabetes in recognition of #WorldDiabetesDay and #DiabetesAwarenessMonth. Check out this single cell resource for the developing human pancreas: https://t.co/Xgn2oZ37Ow
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The package contains 24 palettes that are colorblind friendly, and a mix of qualitative, diverging, and sequential palettes. The package also contains functionality for {ggplot2} to easily incorporate into your data visualizations.
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This is simply an extraordinary study. Researchers gave $7,500 (CAD) to homeless people in Vancouver. The result? The program *saved* money. It helped many of them to move into housing faster, which saved the shelter system $8,277 per person. 🧵👇
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Thrilled to be part of Team decrypTEd, shortlisted for @CancerGrand! It's been wonderful working with all the brightest and kindest souls on this team @Trono_Lab @elisa_oricchio @VallotCeline @ozgendeniz_ @Mehdipour_lab @BenjaminWerner_ @CedricFeschotte
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Van Andel Institute is honored to be recognized with a LEED Green Building Legacy Award at the recent @USGBC East North Central Region Leadership Awards. Learn more about how sustainability has been foundational to VAI since day one:
vai.org
Read about A decade of ‘green’ leadership on Van Andel Institute – Stay updated on the latest research and groundbreaking discoveries in science and health.
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