Inst Metabolic Science-Metabolic Research Labs
@IMS_MRL
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Institute of Metabolic Science-Metabolic Research Labs. Research into diabetes, obesity and related endocrine and metabolic disorders.
Cambridge Biomedical Campus
Joined December 2016
RT @Cambridge_Uni: New map of the brain a game-changer for tackling obesity and diabetes, says @GilesYeo ๐ง @IMS_MRL @MPI_Metabolism scientโฆ
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RT @CambridgeBRC: Researchers from @AngliaRuskin @RoyalPapworth @Cambridge_Uni @UniofHerts @ccs_nhst @CRUK @HLRI_Cambridge @TheCIMR @IMS_MRโฆ
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RT @acmedsci: Weโre empowering early career scientists through our Springboard scheme ๐ฑ Over 350 researchers, like Dr @FlorianMerkle, haveโฆ
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RT @MPI_Metabolism: ๐จPublication alert๐จ @Nature We're excited to introduce HYPOMAP, a comprehensive cell atlas of the human hypothalamus! hโฆ
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RT @JohnTadross: ๐ Want to dive in? ๐บ๏ธ Data: This is just the beginningโmore to come as we expand our map of theโฆ
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RT @JohnTadross: ๐ข Huge thanks to my amazing coauthors @gkcdowsett, Lukas Steuernagel (@MPI_Metabolism), & @brianlamx, and to our senior auโฆ
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RT @JohnTadross: ๐งฉ Key finding #3: More than just metabolism The hypothalamus controls sleep, stress, reproduction & circadian rhythms. Ourโฆ
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RT @JohnTadross: Cont - ๐ Key finding #2: The hypothalamus is architecturally complex - the VMH for example contains at least 5 spatially sโฆ
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RT @JohnTadross: ๐ฌ Key finding #1: Humans โ Mice Hypothalamic neurons in humans & mice look similar, but key differences matter! Example: Gโฆ
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RT @JohnTadross: ๐ง Whatโs in HYPOMAP? We profiled 433,369 hypothalamic cells using single-nucleus RNA sequencing + spatial transcriptomics,โฆ
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RT @JohnTadross: ๐ฌ Why does this matter? The hypothalamus regulates hunger, sleep, stress & metabolism, but most of what we know comes fromโฆ
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RT @GirtonCollege: ๐ New paper by our Fellow out in @Nature today! Explore the insights uncovered in this 'atlas of cells' in the human brโฆ
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RT @JohnTadross: ๐จ New paper in @Nature! ๐จ Weโve mapped the human hypothalamus in unprecedented detail, revealing key differences from miceโฆ
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Further details -
I am excited to share our latest paper @Nature where we construct a hi-res spatial map of the human hypothalamus, the brain region central in appetite control. It is a collaboration between @IMS_MRL @Cambridge_Uni & @MPI_Metabolism
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HYPOMAP: A breakthrough in understanding metabolic health by researchers @IMS_MRL and @MPI_Metabolism, providing an unparalleled view of the brainโs appetite centre & helping to accelerate development of therapies for obesity and diabetes. @Nature
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Research led by @maria_chond and @gr_panayio @MRC_Epid suggests people with detectable BAT, who are metabolically healthier, may be better able to cope with the effects of cancer without experiencing severe weight and muscle loss (cancer cachexia). ๐๐
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RT @CamNeuro: ๐ด๐๐ต @camneuro ๐ฆ๐๐บ๐ฝ๐ผ๐๐ถ๐๐บ ๐๐ป๐๐ฒ๐ฟ๐๐ฒ๐ป๐๐ถ๐ผ๐ป๐ & ๐ฅ๐ฒ๐ฐ๐ผ๐๐ฒ๐ฟ๐ |๐ญ๐ฌ-๐ญ๐ญ ๐ฆ๐ฒ๐ฝ๐ โก๏ธ ๐๐ฒ๐ฏ๐๐ถ๐๐ฒ: โก๏ธ ๐ฆ๐ฝ๐ผ๐ป๐๐ผ๐ฟ๐๐ต๐ถ๐ฝ ๐ข๐ฝ๐ฝ๐ผ๐ฟ๐๐๐ป๐ถ๐โฆ
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RT @MikeVacca1979: Oxidative stress leads #MASLD progression & complications: we studied apolipoproteins' oxidation in MASLD patients' seruโฆ
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