Ping Mu 🇺🇦
@PingMu_PhD
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Associate Professor at UT Southwestern Medical Center, study prostate cancer, fan of 3D printing, photography, soccer and action figure. Dad of two corgi.
Dallas, TX
Joined December 2015
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I did nothing but cheerleading; all credit goes to our fantastic postdoc, Dr. Yaru Xu,
@Yaru00473993
and the other incredible coauthors. We are super grateful to
@ElizSMcKenna
for leading the way with the review process and to the reviewers for their amazing support.
Just published concurrently with an
#AACR24
poster—
ZNF397 Deficiency Triggers TET2-driven Lineage Plasticity and AR-Targeted Therapy Resistance in
#ProstateCancer
, by Yaru Xu,
@PingMu_PhD
et al.
@PCF_Science
@utswcancer
@AACR
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3D printed a Millennium Falcon tube rack for my postdoc, “happy trainee, good science”
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My 6-years old gave the red envelope of all his savings to me as Father’s Day gift, so “you don’t need to apply for grant anymore” 😅
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Our work on Nature Cancer today: Ectopic activation of JAK-STAT is the crucial executor of lineage plasticity. It is specifically required for stem-like and multi-lineage cancer cells, but NOT neuroendocrine-like cells.
@PCF_Science
@utswcancer
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Just got tenured and feeling a surprising calm now. Immense thanks to all my lab people, collaborators, colleagues, mentors and friends who carried me cross the line. Now, back to my 80-page response-to-reviewers letter and the pile of R01 reviews due today.
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Our 3rd paper officially got accepted by Cancer Cell, now work on publishing the 4th and 5th papers.
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My student sent me this, made my day. But still not an excuse for your shitty western blot! LOL
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Check out our 1st paper on CHD1's unexpected role in prostate cancer: "The Heterogeneity, the Plasticity and the Resistance". A joyful collaboration with the Sawyers lab, a work supported by PCF.
@CharlesSawyers
@Cancer_Cell
@soulehoward1
@PCF_Science
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Check out our 3rd paper on Cancer Cell: "Braking Bad: How Loss of SYNCRIP Drives Prostate Cancer's Mutational Chaos and Resistance." Discover how SYNCRIP, as an innate molecular brake, controls APOBEC-driven mutagenesis, tumor heterogeneity & resistance:
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My new postdoc just spent an hour teaching me about T cells. What could be better than gaining so much knowledge from a young colleague and trainee? 😆
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Ever wondered about the E2 enzyme driving AR ubiquitination and degradation? We've found it! "UBE2J1 is the E2 ubiquitin-conjugating enzyme regulating androgen receptor degradation and antiandrogen resistance".
@PCF_Science
@utswcancer
@UTSWCancerBio
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Celebrated our two years birthday and our first paper got accepted.
@PCF_Science
@soulehoward1
@utswcancer
@UTSWCancerBio
@GDDgradprogUTSW
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It’s mighty tough to say goodbye to all my awesome mentors and dearest friends at UTSW. Y’all are forever family in my heart, and we’ll always be true Texans, no matter where we roam.
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What can your PhD mentor do?
Truly a day of joy, so so so happy for my first student and his lovely wife.
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Our new paper was published online today at
@CD_AACR
. If you are attending
#AACR2024
, please visit our poster today to hear the first author, Dr. Yaru Xu, discuss her fascinating work.
@PCF_Science
@utswcancer
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One more big story got officially accepted, now back battling the revision of next one.
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Feeling immense pride today as Carla becomes the first student in my lab to cross the finish line. She delivered an outstanding thesis defense and earned her PhD. I hope she enjoys the coffee mug I chose for her. Congratulations, Dr. Rodriguez!
@CarlaRo95
@UTSWCancerBio
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Great to have my mentor and role model Charles visiting our lab for the first time!
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My first graduate student Carla passed her qualify exam too! Very proud of both of you! Now time for some virtual parties! 🎉 🎊
@UTSWCancerBio
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My wife threatens to throw me and my printer out if I keep printing pen holders 😂
#3Dprinting
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Check out our newest work revealing JAK-STAT’s crucial role In Lineage Plasticity-driven AR Targeted Therapy. Back-to-back with stories from
@CharlesSawyers
lab, Pe’er lab and Hsieh lab.
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Check out this awesome new Cancer Cell paper from the Sawyers lab: How cancer-associated fibroblasts secreted NRG1 to support prostate cancer cells escape AR targeted therapy.
@Cancer_Cell
@CharlesSawyers
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What an awesome day with Edge of
@U2
! Great discussion of cancer research
@sloan_kettering
@PCF_Science
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Met the Neowise comet tonight, 70 miles north of Dallas. Photos taken with tripod, 30 seconds exposure. See you next time in 6800 years, Neowise.
#NEOWISE
#neowisec2020F3
#cometNEOWISE
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My 5-year-old asked me if we can make an Olaf after watching Frozen II. OK, here you go. The best part of being parents is having the chance to fulfill someone‘s dream. Don’t remember my dream as a 5-year-old boy gre up in a small town in northwestern China.
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Took the picture of the Super Wolf Blood Moon last night, Dallas Texas, hand hold my camera without a tripod
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My first student, Choushi, just got his PhD! So proud yet sad to see him go. We celebrated with a cake featuring his top achievement: all the memes he presented in lab meetings. My pre-defense speech took revenge for his "dedication" in my earlier tweet.
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Not entirely happy with this dedication. Perhaps tossing the customized gift I got for his defense? 🙄
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Farewell to our incredible student, Choushi, as he continues his scientific journey as a postdoc in the lab of the legend
#ToddGolub
. In honor of Choushi’s famous quote, 'Brad Pitt is PERFECT,' we've prepared some heartfelt goodbye gifts.
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Immense gratitude for this award and the invitation to the distinguished symposium. It's always a pleasure to return to the Big Apple.
#MountSinai
#prostatecancer
@MountSinaiNYC
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Ping Mu Lab online! My wife thinks "Mu Lab" sounds like a lab studying cows, so using "Ping Mu Lab" instead. LOL
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Very happy my 2nd graduate student Choushi just passed his qualify exam today, now an official PhD candidate, great job!
@GDDgradprogUTSW
@QINGZHANG_UTSW
@Zhu_Lab
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Got a thank you note from a very talented high school kid, so happy to be the first stop on her journey to explore the scientific world
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Today, our summer SURF intern, a prodigy finishing a 4-year U. Wisconsin BS degree in 2 years, ends her course. She wrote code, solved key exp issues, and contributed 7-8 major panels to our revision paper. A great grad school catch this fall!
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This is a free link to download and read our paper on Cancer Cell, in case people does not have access to the journal. AddThis | Home
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Can you imagine anything better than meeting our Texan Legend and Hero Willie Nelson?
@WillieNelson
@Transactivator
@AndyAstrachan
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I am saddened that this remarkable comic book-style cover was not selected, but I do not want it to remain hidden: "Braking Bad: How Loss of SYNCRIP Drives Cancer's Mutational Chaos and Resistance", read the paper on Cancer Cell:
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So proud of my student Carla getting this high competitive and prestigious award! We are so grateful to the extraordinary support from UTSW!
Immensely proud of
@CarlaRo95
from
@PingMu_PhD
Lab for obtaining William F. and Grace Kirkpatrick Award for the 'most scientifically meritorious NIH F fellowship grant application'.
@UTSWGradSchool
@utswcancer
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Welcome the first 4 members of Mu Lab: Lauren, Dapeng, Nick and Spencer. Welcome to the team!
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A two weeks biology experiment: we got this little one unexpected from a plant we bought, and now she is a beautiful butterfly! My 5 year boy is so amazed and started to read insect books I bought.... yes that’s the plan
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We are so thrilled to hear this great news and so grateful for the unmatched strong support from CPRIT and UTSW!
BREAKING NEWS: CPRIT announces 74 new grants for over $112 million to expand innovations in cancer research and prevention in Texas. Check out the release for the entire list of awards.
#CPRIT
#TexansConquerCancer
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Congrats to my student Julisa passed her qualify exam, looking forward to all the great science you will do next!
@JulisaGGonzalez
@UTSWCancerBio
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He finished this 14+ set in only one day, which is his 7th birthday gift..... need to find him something more challenging than LEGO, maybe a gene editing project? 😆
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We tired the Jimmy Kimmel Prank "I told my kid we ate all his Halloween Candy", we felt so sorry but also so lucky when the 5 years old said "it's OK". L😂
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Thank you so much for giving me this award!
Congrats to our
#SBUR19
Young Investigator Award recipients!
Ping Mu, PhD,
@PingMu_PhD
Bethany Kerr, PhD,
@BethanyKerrLab
Andrew S. Goldstein, PhD,
@ASGoldstein6
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UTSW super star student Kathia Rodarte presents her work of ASCL1’s new role at AACR Prostate Cancer Meeting
@UTSWCancerBio
@UTSWGradSchool
@utswcancer
#AACRprostate23
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Our very own trainee postdoc Dr. Xiaoling Li
@XiaolingLi8
presented her work at SBUR annual meeting: SYNCRIP is the molecular brake of APOBEC-driven mutagenesis and resistance, recently published on Cancer Cell.
#SBUR2023
#proudmentor
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Ducked out of the meeting for a bathroom break and ran into the Brazil national soccer team. Who knew bathroom breaks could be this legendary?😆⚽️🥅
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Best conference I have attended, amazing talks and fantastic venue. Presented our latest work on prostate cancer lineage plasticity, published in
@CD_AACR
#EMBOCancerEvo
#lineageplasticity
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I am truly honored to receive this award from SAU, a society comprising many pioneering scientists I have long admired. However, I am neither a star nor rising. The real stars are my extraordinary trainees and our Philip espresso machine, tirelessly working behind the scenes.
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Being a super proud mentor to hear my student Carla
@CarlaRo95
got the NIH F31 award. Feel even better than getting my own grant🍻
@UTSWCancerBio
@utswcancer
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The graduation ceremony of my two students,
@CarlaRo95
and Choushi. I could not be more proud, but it is very sad to say goodbye.
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Congrats to
@ZedaZhang
and
@CharlesSawyers
for the Cancer Cell Cover Story! This is really a nice cover, my favorite
#MiyazakiHayao
Style. Also read great preview from Drs. Jacob J. Orme and Haojie Huang :
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I will present our recent work at the NextGen Stars Spotlight Session I: Models, Tumor Heterogeneity, and Epigenetics, Tuesday, June 23, 9am to 11am ET
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Just gave my first online lecture of Cancer Biology, got a lot of great questions from students, actually more than my in person class last year. Students’ safety and healthy are always the priority.
@UTSWCancerBio
@utswcancer
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Got to office 9am Saturday and thought I was the first, then found my student was already here for an hour. Impressed, keep up the hard working and you will find some great things!
#proudPI
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Little boy received his first-ever first-place trophy in the CMTA Solo Piano Contest
@BioAnnie2
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It’s so awesome to be back at the Coffey-Holden Prostate Cancer Academy, I missed this meeting so much! The only meeting requires 10 mins presentation+20 mins questions
#coffeyholden
#prostatecancer
@PCFnews
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Mu lab at
#AACR2024
, where are you from? One wold, one dream, we will conquer cancer together
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Done the first experiment of 2021, hope all of our research will go well this year with exciting discoveries. Happy New Year!🎆🎊
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Big congratulations to our trainees, GDD graduate student Choushi Wang and postdoc Dr. Xiaoling Li
@XiaolingLi8
received the Travel Award at SBUR annual meeting.
@GDDgradprogUTSW
@UTSWNews
@UTSWPostdocs
#SBUR2023
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My 6 years old boy’s first fishing experience, caught a catfish and released it because “his mom wait him for dinner” 😅 ok man but what about your daddy’s dinner tonight? 😆
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Bought 124 used books on Facebook for his little library, all like new condition, total cost $20. Guess he will stop asking for new books for a while 😆
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Cannot do our favorite Christmas tradition in person, so we had a zoom Secret Santa this year! Whoever gave me this dog face mask, don't let me find out who your are LOL
#SecretSanta
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New lab pictures. How can you survive in my lab without knowing what silly face is?? 😜
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Our recent Nature Cancer paper has been chosen by Faculty Opinions as being of special interest in its field and is a recommended article:
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Our own Dr. Su Deng
@turabbit
presented the crucial role of Jak-stat inflammatory signaling in lineage plasticity and antiandrogen resistance at Gordon Research Conference Hormone-dependent cancers
#GRC
@utswcancer
@UTSWNews
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First snow since we moved down to Texas! Three former New Yorkers got too excited 😆
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Best Christmas Gift from Santa: we moved in a brand new tissue culture room~ LOL
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Every time I am preparing a new grant submission 😂 Meme credit to my wife
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Asked the ChatGPT-4 backed AI midjourney to design my lab logo, with my name and a DNA helix in it.
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We really appreciate the support and highlight from NCI!
Using preclinical models in a study supported by an
@theNCI
MERIT Award,
@PingMu_PhD
@utswcancer
et al. showed that ectopic JAK-STAT activation promotes androgen receptor (AR)-targeted
#therapyresistance
in
#prostatecancer
@NatureCancer
.
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We express our profound gratitude for the unwavering support from the NCI, which has been instrumental in enabling our discoveries.
Using experimental approaches in an
@theNCI
supported study,
@PingMu_PhD
@UTSWNews
et al. identified UBE2J1 is a critical E2 ubiquitin-conjugating enzyme that regulates
#AndrogenReceptor
degradation and anti-androgen resistance
@oncogenejournal
.
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My lab manager made this coffee intensity atlas LOL, intensity 6 to 12 from left to right
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Planted some peach trees last year and got a couple of dozen peaches now. Unexpected sweat and juicy
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Zoom is so much better when coming to visual lab meeting. We will still keep our lab meetings this way but with journal club, grant/paper writing workshop, project brain storm and lab comedy show et al. 🤣 Keep as a team and we will all go over this together.
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Joint lab BBQ outing with my buddy Jun’s lab
@leo_jwu
, Texas Spring is so nice that we have to Play Hard, Work Hard
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Giving a talk at Baylor College of Medicine and saw my buddy
@stranddw
is also giving talk here today. Feel like a Dallas boys’ prostate cancer field trip to Houston 😂
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