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Nicola De Maio
@Nicola_De_Maio
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Evolutionary Biology, DNA evolution, pathogen evolution, population genetics, phylogenetics.
Joined September 2013
RT @EBIgoldman: We have a 3-years MRC-funded postdoc position open within the Goldman Group at EMBL-EBI to work on pandemic-scale phylogene…
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RT @EBIgoldman: Great work led by @Nicola_De_Maio from @EBIgoldman, extending the boundaries of what's possible with likelihood analysis of…
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@CorneliusRoemer @RussCorbett @emblebi @ewanbirney @NatureGenet @EBIgoldman @embl @bq_minh @yatishturakhia @prabhavk I think it's hard to perform deep SPR moves and at the same time be of general applicability. MAPLE and UShER only work at short divergence; RAxML is of general applicability like IQtree but takes longer than IQtree due to SPR moves (at least that's my understanding).
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@CorneliusRoemer @emblebi @ewanbirney @NatureGenet @EBIgoldman @embl @RussCorbett @bq_minh @yatishturakhia @prabhavk Please do add an issue. In the meantime, to increase accuracy, I would recommend considering using in newer versions of MAPLE options "--model UNREST" and "----rateVariation", which will make MAPLE use an UNREST substitution model with rate variation.
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@CorneliusRoemer @emblebi @ewanbirney @NatureGenet @EBIgoldman @embl @RussCorbett @bq_minh @yatishturakhia @prabhavk Thank you for trying it out, let us know of any improvements you would like to see!
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RT @emblebi: The amount of data generated during the COVID-19 pandemic put our bioinformatics tools to the test. Introducing MAPLE: a phyl…
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RT @ewanbirney: Really excited that BOSS-RUNS from @weilgunyl and @Rorymatics in @EBIgoldman and @mattloose labs - with me as an cheerlead…
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RT @EBIgoldman: Really proud of this research that we published last week: It bugged me for years that so much seq…
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Interested in an intership with us at @EBIgoldman in 2023, involving phylogenetics or sequencing technologies? Let us know! Students from French universities are particularly encouraged to apply.
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RT @KosiolG: Apply for a PhD with us! Kosiol Group is looking for PhD students to work on Experimental Evolution to…
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RT @EBIgoldman: EMBL’s newest postdoctoral fellowship programme, EIPOD-LinC, is open for applications. Our Group @EBIgoldman is keen to tal…
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@RobLanfear Oh, and for things like phylogeography/discrete trait analysis/ancestral state reconstruction one would put lots of statistics regarding the trait of interest, like the most probable a posteriori trait value, the posterior distribution of traits, etc
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RT @phyloseminar: Nicola De Maio @nicola_de_maio will be giving the next talk Wednesday, October 5 at 9:00 AM PDT on "Some phylogenetic les…
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