Summary of Autosomal dominant polycystic kidney disease (ADPKD) part1 #nephSAP 🧵

@goKDIGO @kidneydoc101 @BradRovin @ISNWCN @ISNkidneycare Which time zone?

@DrNeilStone And all from IT and research centre 😑

@teachplaygrub Do you know AI websites that can help with imaging?"

Differential Diagnosis ▪️Acquired Kidney Cysts: ↑ with age, no family history •0% (15-29 yrs) •1.7% (30-49 yrs) •11.5% (50-70 yrs) •22.1% (≥70 yrs) •Bilateral cysts rare <50 yrs ▪️ Localized Cystic Disease: Single kidney, no family history, non-progressive. ▪️ Acquired Cystic Kidney Disease: Small bilateral cysts in CKD, ↑ risk of RCC, normal/small kidney size. ▪️ Drug/Metabolic Cysts: Lithium, crizotinib, dRTA, Carney complex, rickets. ▪️ Collagen Mutations: HANAC, thin basement disease → cysts + microhematuria. ▪️ Parapelvic Cysts: Lymphatic cysts sparing cortex (≠ADPKD). ▪️ Medullary Sponge Kidney: Medulla cysts, stones, nephrocalcinosis, normal cortex. ▪️ Genetic Cystic Diseases: •ARPKD •TSC: Angiomyolipomas, facial signs. •VHL: Cysts + retinal, clear cell cancer. •ADTKD: Small kidneys, gout. •HNF-1B: Cysts + systemic signs. •OFD1: Cysts + oral, facial, digital anomalies.

@renal_nerd Thanks😎

🆕 What’s new in TMA management during pregnancy?