LindaXu
@LindaXu78579563
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Postdoc Research Fellow in Jasin Lab @MSKCancerCenter PhD from Department of Biochemistry, University of Oxford
Oxford, England
Joined September 2020
Finally my PhD work is published now in Molecular Cell! Many thanks to my supervisor Prof. Matthew Whitby and all the other co-authors!
Online Now: DNA nicks in both leading and lagging strand templates can trigger break-induced replication
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2/We found that both nicks in leading/lagging strand templates are actively converted in two-ended DSBs by replication, which can be repaired through homologous recombination. At the same time both leading and lagging strand template nicks can induce BIR
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1/We have used CRISPR-Cas9 nickases and other nicking enzymes to generate site-and strand-specific SSBs to study the repair of broken DNA replication forks in fission yeast.
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RT @Divya_ch_: 1/ Excited to share my final PhD work out now in @CellSystemsCP ! ‘The master regulator OxyR orchestrates bacterial oxidati…
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RT @Arnab_RC1: Very excited to present the latest preprint from our lab! "FIGNL1 inhibits homologous recombination in BRCA2 deficient cells…
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RT @SamanthaBRegan: Excited to share our preprint of my PhD work in the Jasin lab @MSKCancerCenter! We find that CRISPR Cas9-induced DNA do…
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RT @ManishaJalan: (1/n) Thrilled to share our newly published study from @simonpowell213 lab in @NatureComms that reveals RAD52's role in p…
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RT @Divya_ch_: 1/ Thrilled to share my final PhD project out as a preprint! A simple regulatory network coordinates a bacterial stress re…
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RT @DrCarlMorrow: Here's the latest paper from the Whitby Lab! We look at the fate of over-replicated DNA from reversed replication forks,…
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