Lehtinen Lab
@LehtinenLab
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basic & translational research on CSF-based signaling & choroid plexus • find us @HMS_Neuro & @BostonChildrens Pathology Dept • // account run by lab members
Boston, MA
Joined December 2019
🌟 Review alert: Curious about the role of the ChP in multiple sclerosis (MS) neuropathology🧠? Check out @Alex_H_Bio review on how the ChP regulates CSF💧immune infiltration and signature + contributes to CSF composition in MS.
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🌟Check out this thread from recent PhD graduate @ScienceYael, who led this wonderful review about the roles of the choroid plexus in disease! 🧠
🧵1/ 🚨 TL cleanse good news! 🚨 Excited to share our review, Choroid Plexus Pathophysiology, now out in Annual Review of Pathology! 🧠 The ChP plays critical roles in CNS health, disease, and maybe therapy.
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🌟@biorxivpreprint alert: Looking for a non-rodent model for pediatric TBI? @Alex_H_Bio leads work across development and regions in 🐷🧠’s that replicates human infant TBI pathophysiology with @costinebartell! Check out now on:
1/ 🧵 Severe TBI in early childhood is an understudied & devastating condition.
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In our latest collaborative effort with @andermann_mark’s group, preprint out now on @biorxiv_neursci, @pnkalugin and team record up to 10 molecules in the CSF 💧 simultaneously in awake, behaving mice 🐭…Check out the videos! 📹
I’m thrilled to share our preprint presenting MORSE: a new way to simultaneously and quantitatively track patterns of neuromodulators/neuropeptides in vitro & in vivo using spatially multiplexed 3D imaging of 10+ green optical sensors on a microendoscope.
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RT @ScienceYael: Huge congrats to the legendary @LagaresLinares for submitting his NSF-GRFP today!!! Cool things coming from @LehtinenLab’s…
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RT @ScienceYael: Super thankful for my excellent PI, @LehtinenLab, who let me lead every step of revision. I went through comments w a fi…
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RT @ScienceYael: All smiles because I just resubmitted the primary first author manuscript resulting from my thesis work!!! I really appr…
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RT @DrEllaOfScience: What an amazing neurodegeneration focussed Northern Lights meeting! @liisamyllykang1 @helsinkiuni My brain is filled w…
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RT @LongevityPapers: @LeilaAkkari1 6. The choroid plexus synergizes with immune cells during neuroinflammation @CellCellPress
https://t.co…
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RT @KanarekNaama: We profiled embryonic CSF in a mouse model of maternal immune activation (MIA) with @PetrovaLabMUW and @LehtinenLab. Now…
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RT @DAgalliu: If you are interested in Brain Barriers I highly recommend reading this beautiful paper in @CellCellPress from @LehtinenLab a…
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RT @CellCellPress: In the latest issue! The choroid plexus synergizes with immune cells during neuroinflammation
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Congratulations to THREE new Lehtinen Lab PhDs: @pnkalugin @mezawadzki @ScienceYael. 🎉 We enjoyed 3 excellent defenses in 24 hours, representing years of work. Good luck to Peter & Miri as they return to medical school to complete MD/PhDs, & to Ya’el in her postdoc at Stanford!
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“Technological advances allowed us to uncover this exciting biology that no one ever expected.” - Thank you to @BostonChildrens for featuring our recent work on ChP management of brain inflammation (ft. @ordovas_phd and @plotfy33) on their Answers blog!
Out in @CellCellPress now with added data and analysis! @Huixin_BJ and colleagues report that the choroid plexus has specialized epithelial-immune synergy that modulates epithelial barrier plasticity during brain inflammation.
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RT @LukensJohnR: The choroid plexus synergizes with immune cells during neuroinflammation @CellCellPress
https://…
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