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RodrigoLedesma-Amaro Profile
RodrigoLedesma-Amaro

@LedesmaAmaro

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Group leader at Imperial College, where engineering meets biology. Synthetic Biology & Metabolic Engineering.

London, England
Joined January 2016
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@LedesmaAmaro
RodrigoLedesma-Amaro
7 months
I am hiring 1 #Postdoc and 2 #PhD students on #syntheticbiology and/or #metabolic engineering at @imperialcollege !! 1 Postdoc position (3 years): 2 PhD Marie Curie positions: Any questions please get in touch!
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@LedesmaAmaro
RodrigoLedesma-Amaro
4 years
Thrilled to announce that I have been awarded an ERC starting grant #ERCStg to work on #synbio , microbial communities and #biotech at @ImperialBioeng & @IC_CSynBio . Thanks @ERC_Research ! I will be looking for Postdocs and PhDs soon!
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@LedesmaAmaro
RodrigoLedesma-Amaro
2 years
I can finally share our last work on #CRISPR for metabolic engineering just out in @naturecomms We developed a highly multiplexed, inducible system for simultaneous activation and repression of target genes. I summarise some key results below (1/6)
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@LedesmaAmaro
RodrigoLedesma-Amaro
2 months
Please RT: I am hiring for a unique position of Research Fellow / Senior Researcher / Senior Postdoc! Join my #synbio lab @imperialcollege to coordinate and supervise research, apply for grants, write papers, and assist managing the team. ➡️ Apply now!
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@LedesmaAmaro
RodrigoLedesma-Amaro
2 months
I am honoured to take on the role of Director at the new Bezos Centre for Sustainable Protein at @imperialcollege , where we will address some of the greatest challenges of our food system. I can't wait to bring this project to life! @BezosEarthFund #Sustainability #engbio
@imperialcollege
Imperial College London
2 months
Our new Bezos Centre for Sustainable Protein has launched today! 🎉 @BezosEarthFund has granted us $30 million to establish the Centre. Together, we will transform our food systems and protect our planet 🌍💚
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@LedesmaAmaro
RodrigoLedesma-Amaro
1 year
I am super excited to share our latest work published in @nchembio This is a story about synthetic microbial communities that helps us understand microbial interactions and construct better biofactories! #synbio #meteng Full paper: Summary below 👇🏼
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@LedesmaAmaro
RodrigoLedesma-Amaro
3 years
Feeling honoured to have received the @imperialcollege President’s Awards for Excellence in Research - Medal for Outstanding Early Career Researcher. I am thankful to everyone who made it possible, especially @ImperialBioeng , @IC_CSynBio and my team!
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@LedesmaAmaro
RodrigoLedesma-Amaro
7 months
Our last work is now out in @NatureMicrobiol ! We developed a molecular toolkit to engineer microbial communities. It enables the control of population dynamics and demonstrated that synthetic communities improved the production of a food antioxidant 🍇
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@LedesmaAmaro
RodrigoLedesma-Amaro
4 years
Thanks a lot @MetabolitesMDPI I feel truly honoured for the Award!! #synbio #meteng @ImperialBioeng @IC_CSynBio
@MetabolitesMDPI
Metabolites MDPI
4 years
#MDPIMetabolites We are pleased to announce that the winner of the Metabolites 2020 Young Investigator Award is Dr. Rodrigo Ledesma-Amaro, from Imperial College London, UK. Read more:
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@LedesmaAmaro
RodrigoLedesma-Amaro
1 year
Bad news ☹️: Our food system is far from perfect and highly unsustainable Good news 🙂: Engineering Biology and #synbio give us the tools to rethink food manufacturing ➡️ In our last review, @aliciagraham22 and I discuss the promise of microbial food
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@LedesmaAmaro
RodrigoLedesma-Amaro
3 years
Wouldn’t it be great (and cheap) to control gene expression with electricity? In our last preprint, we present an expanded toolset (including novel genetic parts, circuits and devices) to do so. Great to see iGem projects developing into papers!
@JMLawrence_
Josh Lawrence
3 years
Our preprint detailing the tools we’ve made for controlling gene expression with electrochemistry is available to read now! Really proud to be a part of this work done by @LedesmaAmaro lab, @imperialigem , and many others. #SyntheticBiology #Bioelectrochemistry #iGEM 1/2
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@LedesmaAmaro
RodrigoLedesma-Amaro
2 years
This is finally out! We have built a model for the fastest growing bacteria known to date: V. natriegens. The model is able to predict growth, gene essentiality, substrate utilisation,metabolic fluxes and resource allocations. Great collaboration UK-USA-Spain. #synbio & #sysbio
@MolSystBiol
Mol Syst Biol
2 years
The first genome-scale metabolic model of Vibrio natriegens brings insights into metabolism, halophilic adaptions & resource allocation ➡️ @LedesmaAmaro @imperialcollege #SynBio #metabolicengineering
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@LedesmaAmaro
RodrigoLedesma-Amaro
3 years
We are hiring motivated #postdocs to work on #synbio and #meteng with one of my favourite bugs, Yarrowia lipolyitica. Advanced metabolic pathway engineering at @IC_CSynBio with great Industrial and Academic partners. Please apply, get in touch or RT.
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@LedesmaAmaro
RodrigoLedesma-Amaro
4 years
Central carbon metabolism can be dynamically controlled to maximise the production of value chemicals! This is achieved by a synthetic feedback loop linked to gene activation/repression. Great #synbio collab with Prof Long. Find our article at @nchembio :
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@LedesmaAmaro
RodrigoLedesma-Amaro
1 year
I have a 2 years postdoc position open to work on #meteng and #synbio at @imperialcollege Metabolic Engineering of the yeast Yarrowia lipolytica for lipid production in collaboration with @valley_dao . Apply now 👇🏼
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@LedesmaAmaro
RodrigoLedesma-Amaro
3 years
Thanks for the #SRUKTalent Award @ComunidadCeru & @FBancoSantander ! It’s a real honour! (Apologies Twitter World for the recent unexpected self-promotion tweets. It’s been a happy/lucky week)
@ComunidadCeru
SRUK/CERU
3 years
SRUK Emerging Talent Award We are pleased to announce that Dr Rodrigo Ledesma Amaro @LedesmaAmaro has been awarded the 2021 #SRUKTalent Award, a prize sponsored by @FBancoSantander to recognise the talent and innovation of Spanish researchers in the UK!
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@LedesmaAmaro
RodrigoLedesma-Amaro
3 years
I am looking for a postdoctoral researcher to work on #synbio and/or metabolic engineering at @imperialcollege London ( @IC_CSynBio @ImperialBioeng ) 🧫 Meet the group: 📩 Get in touch: r.ledesma-amaro @imperial .ac.uk
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@LedesmaAmaro
RodrigoLedesma-Amaro
4 years
Looking for a #postdoc in synthetic biology and metabolic engineering?join our lab at @ImperialBioeng and @IC_CSynBio . Meet the group at . Info and applications here further questions via email. #synbio & #meteng . Please RT
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@LedesmaAmaro
RodrigoLedesma-Amaro
1 month
Last work from the group out of the press in @NatureComms ! Here we looked at baker yeast 🥐🍺 through the single-cell lenses 🔎🦠 We found out genetically identical subpopulations with different behaviours emerging in response to amino acid identity.
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@LedesmaAmaro
RodrigoLedesma-Amaro
2 years
Congratulations to @aliciagraham22 who got her PhD!! Amazing work on turning microbes into #nutritious and #sustainable food! Truly multidisciplinary effort with publications to come. Stay tuned! #synbio for #Sustainability at @IC_CSynBio , @imperialcollege , @ImperialBioeng
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@LedesmaAmaro
RodrigoLedesma-Amaro
2 years
I am looking for 2 #postdocs to join my group at @imperialcollege , @IC_CSynBio , @ImperialBioeng . 1️⃣ Metabolic engineering in Yarrowia 2️⃣ #synbio in bacteria! Both are part of cool international collaborations! Please RT
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@LedesmaAmaro
RodrigoLedesma-Amaro
3 years
Some pics from our lab away day in Brighton on Friday. It was real fun! Thanks everyone for such a nice day and especially @aliciagraham22 and Kiyan for organising an amazing treasure hunt! And the invited PI @DrLeoRios for joining!
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@LedesmaAmaro
RodrigoLedesma-Amaro
2 years
We are looking for a #postdoc to work on metabolic engineering and #synbio ! The position is aimed at engineering Y. lipolytica to develop a new process with commercial potential! Join us at @imperialcollege , @IC_CSynBio , @ImperialBioeng . Please RT 🙏👇🏼
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@LedesmaAmaro
RodrigoLedesma-Amaro
5 years
Semi-synthetic microbial communities can improve bioproduction! Have a look at our proof of concept article, especially if you like soy sauce ;) #synbio with @DrTomEllis @gilbertlatoani @lookida
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@LedesmaAmaro
RodrigoLedesma-Amaro
3 years
Have a look at our #synbio review about C1 substrates utilisation (methanol, formate, CO2 and others) just out in @nchembio . Amazing labs have done amazing progress in this field! Is efficient C1 utilisation in heterologous microbes possible by #meteng ? >>
@nchembio
Nature Chemical Biology
3 years
A review article by @LedesmaAmaro @weijian16329397 and colleagues surveys natural metabolic pathways for utilization of C1 substrates and their adaptation towards creating synthetic C1-utilizing microbes. Free to read:
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@LedesmaAmaro
RodrigoLedesma-Amaro
2 years
I was about to tweet about our last paper, aimed to use electricity to control gene expression, but would not be better than the amazing summary by @JLawrence_96 ⬇️ For those far from the #synbio field, you can know more about this work here:
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@JMLawrence_
Josh Lawrence
2 years
Ever wanted to turn on a gene with electricity? Our work on #synbio and #electrochemistry tools for electronic control of gene expression is out now in @ScienceAdvances ! ⚡🦠 Here's a summary of our findings 🧵 1/11
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@LedesmaAmaro
RodrigoLedesma-Amaro
6 years
Exciting upcoming postdoc position in my group at Imperial College! Interested in Synthetic Biology and microbial communities with cool biotech applications? Contact me!. Working closely with @DrTomEllis and @gbstan . Please RT
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@LedesmaAmaro
RodrigoLedesma-Amaro
2 years
Congratulations to Dr Lucie Studena who has just got her well deserved PhD degree! Thanks to Prof @gbstan and Prof Paul Fraser for being the examiners. Thanks @ProfTomEllis for the cosupervison. Cool stuff on microbial communities, #CRISPR and #bioproduction !
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@LedesmaAmaro
RodrigoLedesma-Amaro
2 months
We are hiring 1 academic and 3 manger positions to join the new Bezos Centre for Sustainable Protein @imperialcollege ➡️1 PI position to work on alternative proteins ➡️1 Centre Manager ➡️1 Head of impact, innovation and growth ➡️1 Marketing and communications Lead ➕info⬇️
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@LedesmaAmaro
RodrigoLedesma-Amaro
3 years
Just received the hard copy of the “Yarrowia lipolytica methods and protocols” freshly edited by @MarkBlenner and @LabWheeldon ! Happy to have contributed to it together with @LabAlper , @Irina__Borodina , and many others. #meteng #synbio #yarrowia
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@LedesmaAmaro
RodrigoLedesma-Amaro
2 years
Don’t miss the February issue of @CellSystemsCP ! It is all about microbial communities! 🦠 Cool perspectives & reviews and many different opinions on the “key challenges for engineering microbiomes” (including my two cents on the topic). 👇🏼
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@LedesmaAmaro
RodrigoLedesma-Amaro
3 years
2 days left to apply for this Postdoc position! #postdoc #synbio #meteng @ImperialBioeng @imperialcollege
@LedesmaAmaro
RodrigoLedesma-Amaro
3 years
We are hiring motivated #postdocs to work on #synbio and #meteng with one of my favourite bugs, Yarrowia lipolyitica. Advanced metabolic pathway engineering at @IC_CSynBio with great Industrial and Academic partners. Please apply, get in touch or RT.
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@LedesmaAmaro
RodrigoLedesma-Amaro
2 years
Having some fun with the team in our end of winter social! 🎳 We missed a few people enjoying well deserved holidays ⛷ so we should start planning the next one! What should we do next? It’s great to be able to meet in person and celebrate together again!
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@LedesmaAmaro
RodrigoLedesma-Amaro
1 year
By now you have probably realised that our food system is highly unsustainable! What can we do about it? What are we (researchers, industry, stakeholders) doing about it? Join our Forum next Tuesday and learn about the future of food 🥘👇🏼 @imperialcollege #Sustainability #Food
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@LedesmaAmaro
RodrigoLedesma-Amaro
2 years
Well done @IgemImperial team in your first presentation at the #iGEM2022 jamboree! If you 🫵🏼 are in Paris tomorrow Thursday, don’t miss their talk at 14:00 in plaza 4 and learn how engineered spores can help fight hunger & come to the poster to discuss with the team! 🦠⚙️🌱
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@LedesmaAmaro
RodrigoLedesma-Amaro
1 year
Great #fems2023 conference in Hamburg with a cherry on top: best poster award to @KiyanS1 for our heterogeneity work ( @ERC_Research )!Well done Kiyan 👏🏻👏🏻
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@LedesmaAmaro
RodrigoLedesma-Amaro
1 year
#synbio meets skin microbiome! We have just launched our multidisciplinary EIC pathfinder project #SkinDev with an amazing kickoff event in Barcelona. I am already learning so much! Thanks @Synbio_Lab_UPF for a great organisation.
@UPFbiomed
UPF Medicine and Life Sciences
1 year
1/3🧬🦠Green light for the EU project #SkinDev to engineer skin microbiomes for detecting and treating skin inflammation. 👩🏽‍🔬👨🏿‍🔬 @Synbio_Lab_UPF , @TanakaGroup , @LedesmaAmaro , Ellen Van den Bogaard & Bernhardt Homey 💵 European Innovation Council 👉🏽
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@LedesmaAmaro
RodrigoLedesma-Amaro
2 years
Great talk and discussions by @Moon_Synth_Bio at @IC_CSynBio ! Great learnings from your science and a boost of motivation 💪🏼
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@LedesmaAmaro
RodrigoLedesma-Amaro
1 year
I am looking for an Operating and Grant Manager to join my lab! If you like #synbio and would like to take part in shaping the next grants and research directions of the lab and be involved in brainstorming, writing and execution (no actual experiments), get in touch! ✉️
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@LedesmaAmaro
RodrigoLedesma-Amaro
5 years
Delayed celebration of the Lunar New Year in a budding table!
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@LedesmaAmaro
RodrigoLedesma-Amaro
3 years
Picnic in Hyde Park with part of the team. Farewell @mgracialvan and Yulin! All the best for your future adventures!
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@LedesmaAmaro
RodrigoLedesma-Amaro
9 months
Winter celebrations in the lab! RLAlab themed escape room + secret Santa + nice food and best company!
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@LedesmaAmaro
RodrigoLedesma-Amaro
1 year
Amazing retreat/away day of the lab at Kew Gardens! Plant-based treasure hunt with an AI touch organised by @JulineSavigny @MohamedAlMarei @eliza_atkinson @diegorsanchis ! out of breath but lots of fun!
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@LedesmaAmaro
RodrigoLedesma-Amaro
3 years
Great to have @jijzarco as guest speaker in our group meeting today! Interesting learnings about cheating (microbiologically speaking) 🧫🤥
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@LedesmaAmaro
RodrigoLedesma-Amaro
1 year
3 days left to apply for this postdoc position to join my lab and lead a cool project supported by @valley_dao ! 👇🏼👇🏼
@LedesmaAmaro
RodrigoLedesma-Amaro
1 year
I have a 2 years postdoc position open to work on #meteng and #synbio at @imperialcollege Metabolic Engineering of the yeast Yarrowia lipolytica for lipid production in collaboration with @valley_dao . Apply now 👇🏼
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@LedesmaAmaro
RodrigoLedesma-Amaro
5 years
Lab meeting + science museum lates! ^^
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@LedesmaAmaro
RodrigoLedesma-Amaro
2 years
Wow @IgemImperial made it to the top 10 #iGEM2022 ! Huge congratulations for the well deserved recognition! Bring some croissants to celebrate :) #proudsupervisor Learn more about the project: @ImperialBioeng @imperialcollege @IC_CSynBio
@LedesmaAmaro
RodrigoLedesma-Amaro
2 years
Well done @IgemImperial team in your first presentation at the #iGEM2022 jamboree! If you 🫵🏼 are in Paris tomorrow Thursday, don’t miss their talk at 14:00 in plaza 4 and learn how engineered spores can help fight hunger & come to the poster to discuss with the team! 🦠⚙️🌱
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@LedesmaAmaro
RodrigoLedesma-Amaro
2 years
Really looking forward to welcoming @PabloINik in London!
@IC_CSynBio
Imperial College Centre for Synthetic Biology
2 years
Next IC-CSynB seminar on 8 February - by Prof Pablo Nikel (DTU Biosustain) @PabloINik ! Join us to hear about extreme cellular chemistry by metabolic engineering! In person (SAF120, ICL SouthKen) or online. Open to everyone! Sign up here:
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@LedesmaAmaro
RodrigoLedesma-Amaro
5 years
Happy to represent the UK in this COST Action. Glad to be part of the excellent European Science. 🇬🇧 🇪🇺
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@LedesmaAmaro
RodrigoLedesma-Amaro
5 years
Open PhD position in my group at Imperial College, @ImperialBioeng and @IC_CSynBio in collaboration with @gbstan : Engineering synthetic microbial consortia for next-generation biotechnology! Email me if interested. More info at
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@LedesmaAmaro
RodrigoLedesma-Amaro
4 years
A great #postdoc opportunity in applied computational biotechnology ! Exciting #synbio project and amazing international partners from academia and industry. Apply now!
@gbstan
Prof Guy-Bart Stan
4 years
New PostDoc position in the @gbstan group in collab w/ @LedesmaAmaro , EU partners & industry on "Computational synthetic biology for the bioproduction of high-value molecules in microbial communities". Pls RTs.💻🦠 Details & how to apply (deadline 17 Sep):
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@LedesmaAmaro
RodrigoLedesma-Amaro
6 years
Are you looking for a #postdoc in applied #synbio and metabolic engineering? Join the group at @imperialcollege for this exciting project using the trendy yeast Yarrowia lipolytica: please RT
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@LedesmaAmaro
RodrigoLedesma-Amaro
4 years
1 day left to apply for these Postdoc positions to join our lab!
@LedesmaAmaro
RodrigoLedesma-Amaro
4 years
Looking for a #postdoc in synthetic biology and metabolic engineering?join our lab at @ImperialBioeng and @IC_CSynBio . Meet the group at . Info and applications here further questions via email. #synbio & #meteng . Please RT
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@LedesmaAmaro
RodrigoLedesma-Amaro
7 years
Have a look at our Cell Factory cover in @TrendsinBiotech and our review article on Rhodosporidium!
@TrendsinBiotech
Trends in Biotechnology
7 years
The March issue of TIBTECH reviews rational design of mouse models, multi-omics in aquaculture, lipid yields in algae, yeast cell factories, cold biosurfactants, and more: Articles by @ARC_ABM , @MortenLimborg , @ReneWijffels , @LedesmaAmaro , and others.
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@LedesmaAmaro
RodrigoLedesma-Amaro
6 years
Have a look to our review on synbio tools for Yarrowia!
@synbio_papers
synbiopapers
6 years
Synthetic biology tools for engineering Yarrowia lipolytica.
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@LedesmaAmaro
RodrigoLedesma-Amaro
2 years
A few days left to apply to these postdoctoral positions! Come join us at @IC_CSynBio Get in touch if you have questions 📧 #synbio #meteng #postdoc
@LedesmaAmaro
RodrigoLedesma-Amaro
2 years
I am looking for 2 #postdocs to join my group at @imperialcollege , @IC_CSynBio , @ImperialBioeng . 1️⃣ Metabolic engineering in Yarrowia 2️⃣ #synbio in bacteria! Both are part of cool international collaborations! Please RT
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@LedesmaAmaro
RodrigoLedesma-Amaro
3 years
We are hiring! The Postdoc position in #synbio and/or #meteng is now open for applications at 🇬🇧 Imperial College London 🧫 Meet the group: 📩 Get in touch: r.ledesma-amaro @imperial .ac.uk
@LedesmaAmaro
RodrigoLedesma-Amaro
3 years
I am looking for a postdoctoral researcher to work on #synbio and/or metabolic engineering at @imperialcollege London ( @IC_CSynBio @ImperialBioeng ) 🧫 Meet the group: 📩 Get in touch: r.ledesma-amaro @imperial .ac.uk
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@LedesmaAmaro
RodrigoLedesma-Amaro
6 years
The postdoc position in my lab at Imperial College London is already open! Apply on or contact me for more information! Please RT
@LedesmaAmaro
RodrigoLedesma-Amaro
6 years
Exciting upcoming postdoc position in my group at Imperial College! Interested in Synthetic Biology and microbial communities with cool biotech applications? Contact me!. Working closely with @DrTomEllis and @gbstan . Please RT
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@LedesmaAmaro
RodrigoLedesma-Amaro
5 years
Standard protocols day + Xmas lunch + bowling.. a cool day with the team out of the lab! Thanks guys!
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@LedesmaAmaro
RodrigoLedesma-Amaro
3 years
Congratulations Young-Kyoung Park for your L’Oréal-UNESCO Young Talent Award! Great achievement! We are lucky to have you in the lab, @ImperialBioeng , @IC_CSynBio and @imperialcollege 👏🏻👏🏻👏🏻
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@4womeninscience
For Women in Science
3 years
A huge congratulations 👏👏 to the 35 PhD students and post-doctorates who are part of the L'Oréal- @UNESCO Young Talents France class of 2021.​ Discover the #FWIS program created by the #FondationLOreal and supported by @AcadSciences and @CNFUnesco ➡️
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@LedesmaAmaro
RodrigoLedesma-Amaro
3 years
The Living Revolution is back! Podcasts on synthetic biology (not sure about their choice of guest for this episode 😬 but the others are great!!) 👇🏼👇🏼
@TheLivingRevol
The Living Revolution
3 years
New episode out now! @LedesmaAmaro discussed the field of metabolic engineering - how we can manipulate microbes to produce chemicals, #biofuels , #livingmaterials . You can check it out on #Spotify , #ApplePodcasts , #GooglePodcasts and more.
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@LedesmaAmaro
RodrigoLedesma-Amaro
2 years
Away day with the lab! Enjoying the sunny weather with some outdoor activities. Lots of fun!
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@LedesmaAmaro
RodrigoLedesma-Amaro
1 month
🚨Last days to apply for this senior researcher/scientists position! 👇🏼👇🏼👇🏼
@LedesmaAmaro
RodrigoLedesma-Amaro
2 months
Please RT: I am hiring for a unique position of Research Fellow / Senior Researcher / Senior Postdoc! Join my #synbio lab @imperialcollege to coordinate and supervise research, apply for grants, write papers, and assist managing the team. ➡️ Apply now!
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@LedesmaAmaro
RodrigoLedesma-Amaro
4 years
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@LedesmaAmaro
RodrigoLedesma-Amaro
2 years
2 days left to apply for this postdoc position! Don’t miss it! 🧪🧫🦠🧬
@LedesmaAmaro
RodrigoLedesma-Amaro
2 years
We are looking for a #postdoc to work on metabolic engineering and #synbio ! The position is aimed at engineering Y. lipolytica to develop a new process with commercial potential! Join us at @imperialcollege , @IC_CSynBio , @ImperialBioeng . Please RT 🙏👇🏼
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@LedesmaAmaro
RodrigoLedesma-Amaro
1 year
Great news indeed 🇪🇺🤝🇬🇧
@mpr_nano
Mary Ryan
1 year
Excellent news that the UK rejoins our partners in European research Collaboration is more important than ever to secure a safe, sustainable and healthy future
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@LedesmaAmaro
RodrigoLedesma-Amaro
2 years
(6/6) The team behind: @willmshaw , Lucie Studena, Kyler Roy, Piotr Hapeta, @NikoMcCarty , @aliciagraham22 , @ProfTomEllis (thank you all!) and yours truly. The place: @ImperialBioeng @IC_CSynBio . Thanks for reading until the end 😊
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@LedesmaAmaro
RodrigoLedesma-Amaro
3 months
Super nice (and sunny!) away day with the team. Walking in the London Wetland Centre + bird watching bingo + board/ball games!
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@LedesmaAmaro
RodrigoLedesma-Amaro
1 year
Dont miss this amazing work from Alice Boo on synthetic microbial communities now out as a pre-print! #synbio @ImperialBioeng @IC_CSynBio
@gbstan
Prof Guy-Bart Stan
1 year
Amazing and heroic work by my former PhD student, Dr Alice Boo (now in Chris Voigt’s lab at MIT), and a wonderful collaboration with Harman Mehta (continuing the work of Alice) and @LedesmaAmaro . @RAEngNews @ImperialBioeng
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@LedesmaAmaro
RodrigoLedesma-Amaro
7 years
Check out our last review on Rhodosporidium toruloides for producing specialty chemicals: @TrendsinBiotech #synbio #meteng #biotech
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@LedesmaAmaro
RodrigoLedesma-Amaro
3 years
Fantastic discussions (and cool gif) about the potential of Life Sciences in Space 🪐 with a great intervention by @angeles_hg presenting her work on #synbio for Space Exploration!
@STFC_B2B
STFC Innovations
3 years
Thank you to everyone who joined us for the UK Space Life and Biomedical Science Symposium last week. We were joined by some fantastic speakers within the Space and Health & Life Sciences sectors for our panel discussions and spotlight sessions. @UK_SpaceLABS #SpaceLABS2021
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@LedesmaAmaro
RodrigoLedesma-Amaro
2 years
Hey! Anybody out there could help us (or know someone that could help us) take some TEM images of yeast? 🔬🧫 Thanks a lot!! Something like ⬇️
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@LedesmaAmaro
RodrigoLedesma-Amaro
2 years
A bit of science communication fresh out of the lab! 📽 1. Waste to products with #synbio featuring our #SyCoLim project: 2. Burger of the future by our @IgemImperial team: They need your 👍🏻 for the @ERA_CoBioTech contest!
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@LedesmaAmaro
RodrigoLedesma-Amaro
5 years
Kick-off of the INCREaSE project. The lab is presenting in Wroclaw! Great talks by @aliciagraham22 , @lu_cha_ and Nishta!
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@LedesmaAmaro
RodrigoLedesma-Amaro
1 year
Don’t miss this event on the future of food tomorrow! It’s starts at 9am GMT Join us:
@LedesmaAmaro
RodrigoLedesma-Amaro
1 year
By now you have probably realised that our food system is highly unsustainable! What can we do about it? What are we (researchers, industry, stakeholders) doing about it? Join our Forum next Tuesday and learn about the future of food 🥘👇🏼 @imperialcollege #Sustainability #Food
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@LedesmaAmaro
RodrigoLedesma-Amaro
3 years
@PabloINik @LabNikel Thanks for the invitation! It is really great to see some of the amazing science you and your team are doing :)
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@LedesmaAmaro
RodrigoLedesma-Amaro
3 years
2 days left to apply for this Postdoc position! Reach out if you have any question :)
@LedesmaAmaro
RodrigoLedesma-Amaro
3 years
We are hiring! The Postdoc position in #synbio and/or #meteng is now open for applications at 🇬🇧 Imperial College London 🧫 Meet the group: 📩 Get in touch: r.ledesma-amaro @imperial .ac.uk
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@LedesmaAmaro
RodrigoLedesma-Amaro
6 years
Last days to apply for this postdoc position in my lab! Come and join us to do synthetic biology and metabolic engineering at the @IC_CSynBio !
@LedesmaAmaro
RodrigoLedesma-Amaro
6 years
Are you looking for a #postdoc in applied #synbio and metabolic engineering? Join the group at @imperialcollege for this exciting project using the trendy yeast Yarrowia lipolytica: please RT
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@LedesmaAmaro
RodrigoLedesma-Amaro
4 months
Great to see this neat work published! Well done @MinoJHG and glad to be part of it!
@MinoJHG
Jorge Hernández-García
4 months
I am very happy to present this previously preprinted work, and now published in @PNASNews . A long journey starting as one of my PhD chapters. I cannot but thank all the coauthors for this effort
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@LedesmaAmaro
RodrigoLedesma-Amaro
2 years
(5/6) Metabolic Engineering: We constructed a single gRNA array targeting 11 metabolic genes which allowed us to tune their expression in a single transformation. Succinic acid production increased 60 times! This can speed up strain engineering.
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@LedesmaAmaro
RodrigoLedesma-Amaro
3 years
Looking forward to seeing what we can achieve together! ⬇️⬇️
@DArmstrongJames
Darius Armstrong-James
3 years
I am please to announce we have been awarded a Imperial College London Network of Excellence in Fungal Science. The Network will bring together over 20 principal investigators working across the themes of biotechnology and engineering, infection, ecology and evolution.
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@LedesmaAmaro
RodrigoLedesma-Amaro
1 year
Finally we also tested how syntrophic communities perform in combination with division of labour for bioproduction. Interestingly, in most cases these engineered communities produce higher yields than the monoculture control! (Bottom right graph)
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@LedesmaAmaro
RodrigoLedesma-Amaro
3 years
Also, have a look at the position paper by @UK_SpaceLABS with our two cents contribution
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@LedesmaAmaro
RodrigoLedesma-Amaro
1 year
Thanks to everyone who attended our Forum and Workshop on the future of food!
@ImpEngineering
Imperial Engineering
1 year
What does the future of food look like? We recently hosted Imperial's inaugural Future of Food Forum - exploring the challenges and potential of alternative proteins. Read a write-up:
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@LedesmaAmaro
RodrigoLedesma-Amaro
1 month
@KiyanS1 @ERC_Research @EMBO @imperialcollege @ImperialBioeng @IC_CSynBio @DNAFoundry Yeast are unicellular organisms, but when we investigated what each cell does during certain conditions, we observed 2 subpopulations (genetically identical) performing 2 distinct tasks - resembling what multicellular organisms do! One favours growth 📈 the other lifespan 👵
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@LedesmaAmaro
RodrigoLedesma-Amaro
4 years
A short communication from @imperialcollege on this here:
@imperialcollege
Imperial College London
4 years
Congratulations to our four academics who have won @erc_research Starting Grants this year. The grants recognise some of the best, young scientists across Europe #ERCStG . Find out more:
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@LedesmaAmaro
RodrigoLedesma-Amaro
1 year
All started with my super talented master student @ericsouth_ (now graduate student @DunlopLab ). We started a fantastic collaboration with @RalserLab and it’s robots 🤖. And two super scientists continued the work @LaraSellesVidal & @simranolak , + invaluable help of co-authors
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@LedesmaAmaro
RodrigoLedesma-Amaro
2 years
(3/6) Inducibility: We found out that gRNA arrays targeting prometer regions can express even without a promoter, which makes leakiness an issue. @willmshaw designed a way to stop leakiness which allowed us to control when CRISPR regulation starts.
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@LedesmaAmaro
RodrigoLedesma-Amaro
7 months
We are passionate about sustainability and the greener production of food, ingredients, pharmaceuticals, etc and therefore aimed to produce Resveratrol as a PoC using synthetic communities engineered with our toolkit. Some communities outperformed monocultures!
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@LedesmaAmaro
RodrigoLedesma-Amaro
1 year
One particular case was a bit less expected, a pair that was exchanging pathways intermediates instead of end products (trp2-trp4). We characterised this interaction with MS. Researchers out there working on nutrient exchange in microbiomes should consider all metabolites!
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@LedesmaAmaro
RodrigoLedesma-Amaro
1 year
Big thanks to all other co-authors! Including @HuadongPeng And to the funders @BBSRC @ERC_Research etc And of course @imperialcollege @ImperialBioeng @IC_CSynBio
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@LedesmaAmaro
RodrigoLedesma-Amaro
2 months
1 Academic position 🧑‍🔬️ to work on alternative proteins in the department of Bioengineering available to all levels (lecturer, senior lecturer, reader, professor – equivalent to assistant, associate and full professor). Apply ➡
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@LedesmaAmaro
RodrigoLedesma-Amaro
4 years
@p_maverick_b @Ginkgo Fantastic news! 👏🏻👏🏻 Great for both @Ginkgo and Novogy! Looking forward to see more Yarrowia work taking off!
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@LedesmaAmaro
RodrigoLedesma-Amaro
5 years
@jijzarco @Preprints_org @ManuelSalvaLara @JaimeGoGut Just in time for my UG lecture on Monday about substrates for biotechnology! :)
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@LedesmaAmaro
RodrigoLedesma-Amaro
7 months
The toolkit is based in cross-feeding between 2 or 3 engineered yeast strains:
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