Kunal Desai MD MBA MS
@KunalDesaiMD
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dad x2 | oncologist | Medical Director @abbvie | drug development | Heme/Onc fellowship @uchicago | IM @clevelandclinic | squash | ☕️💊📚
Chicago, IL
Joined April 2020
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I’ve spent the past yr curating a reading list of all things cancer. - it’s history, patient voices, drug discovery / biotech & basic science breakthroughs. Understanding this disease drives every minute of my waking life. Always appreciate recs!
#OncTwitter
#MedTwitter
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Anyone else develop a pathologic inability to relax as a side effect of medical training?
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Everyone should follow
@AuschwitzMuseum
. The stories & pictures are haunting & a constant reminder of the fragility of civil society.
27 June 1933 | A Dutch Jewish girl, Sarah Elizabeth van der Heijm, was born in Rotterdam. Her family emigrated to France.
In 1943 she was deported to
#Auschwitz
and murdered in a gas chamber after the selection.
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Pleased to announce that I have matched at the University of Chicago for oncology fellowship. I have wanted to train there since I was 16. This is a dream come true - is it even real?
@UCCancerCenter
@UCHemOncFellows
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Been on quest for good history podcast given recent events (pandemic, war, etc). And I have found it ➡️
@TheRestHistory
. 2 cheeky British historians
@holland_tom
&
@dcsandbrook
provide [hilarious] in-depth analysis of every major historical trend. Can't stop won't stop listening.
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With a 2-hour daily commute, I listened to >250 hours of podcasts. 🥸
It was great to listen, reflect & learn about the things I love:
🧬oncology
💊drug development / biotech
🏺history
📈business / geopolitics
📚print media (books & mags)
Below are favorites by category ⬇️
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7
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🧬💊📚Re-reading a classic over the holidays. There is no better biography of cancer: from ancient times to present. Can’t believe 13 yrs since its publication.
The Ken Burns documentary adaptation is beautiful — but emotionally raw.
What an incredible time to be in the field
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2010-2020: left corporate world, went to med school, (almost) done w/residency, matched to dream Fellowship program, will become an oncologist. More importantly: met a girl, fell in love, got married, had 2 beautiful kids. Grateful for the past decade & excited for the next.
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Thrilled to be selected for
@UChicago
’s Clinical Pharmacology Fellowship:
@NIH
T32 program that combines didactics, mentoring + protected research time(80%). Lays theoretical foundation for continued study of 𝘥𝘦 𝘯𝘰𝘷𝘰 drug discovery. Blessed to be training at
@UChicagoHemOnc
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Meet the hardest working Residents to graduate from the
@ClevelandClinic
IM residency this year. This year’s Chiefs have been the utmost when it comes to professionalism, responsiveness (esp in the COVID era) + empathy. Wish them the best & a big thank you!
@CCF_IMCHIEFS
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Top biotech podcasts 🧬💊. History of the industry + current innovations told through analysis + interviews w/CEOs, CSOs, CMOs, VCs. Each brings its own flavor. I rarely miss an episode - so good.
@NatureBiotech
@bradyhuggett
@BioCentury
#MattPillar
#ErinHarris
@ldtimmerman
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10
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Every 1st year oncology Fellow should get a copy of the
@ASCO
SEP book. It’s a “one-stop-shop” for all tumor types + other topics like clinical pharm, epi, IO, etc. It also describes key trials for each Tx. You can always supplement the basics w/additional papers.
#Onctwitter
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#1
reason I chose
@ClevelandClinic
for IM residency
@CCF_IMCHIEFS
was its strong track record for Fellowship Match. Well, it’s only gotten stronger under leadership of
@Mud_Fud
- congrats. Here’s sample of institutions from this yr’s Match ➡️
@UCSF
@JohnsHopkins
@Penn
@MayoClinic
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370 miles, 2 kids, 3 stops (one being McDonald’s) and 7 hours - to cap off 3 incredible years in Cleveland. Thanks for the memories. Hello Chicago, old friend - I’ve missed you.
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Best Christmas gift ever: matching at
@UChicago
@UCHemOncFellows
(and the sweatshirt). Still hasn’t sunk in to be honest.
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Beautiful early Monday morning in Chicago before the maddening crowds arrive.
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Met a girl 10 years ago who loved being a doctor. So much so that she inspired me to leave the corporate world & become a doctor. 8 years of marriage & things just keep getting better.
@DrAnitaRaghavan
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Many thx to
@ClevelandClinic
@CCF_IMCHIEFS
@abbyCCim
for the excellent training that got me to
@UCHemOncFellows
! Will absolutely miss my mentors + Fellows -
@NimaSharifiMD
@MosheOrnsteinMD
@TimGilliganMD
@irisyshengMD
@AmandaNizamMD
. No one told me how bittersweet this would be.
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When I evaluated residency programs, I looked at where residents matched for Fellowship.
@ClevelandClinic
’s IM residency absolutely crushed Match this yr. Lots of residents @ elite institutions across specialties. This is a power institution. Congrats to
@CCF_IMCHIEFS
@abbyCCim
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When that prominent oncologist you’ve been following on
@Twitter
is now your Attending. So much to learn about lung cancer from
@marinagarassino
. I love this job.
@UCHemOncFellows
@UCCancerCenter
#FellowLife
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Cleveland is an awesome city to raise kids. Lots of parks/hiking + affordable housing + [Montessori] school + no traffic. Avi likes to escape the hustle n bustle & chill at the
@holdenarboretum
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Well, it’s official — we just bought a house 🏠. Never gonna leave this town now. Kids thriving,
@DrAnitaRaghavan
loves working at
@ComerChildrens
&
@UChicagoHemOnc
has been awesome.
On a related note — Onc Fellow looking for job in Chicagoland area come summer 2024. 😆
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Last day at
@ClevelandClinic
. All good things come to an end. Thanks for the memories 🥲
@CCF_IMCHIEFS
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Wow wow wow — the
@EmpirePodUK
team (
@tweeter_anita
&
@DalrympleWill
) have done it again — kicked off a new series on the Persian empire. Great discussion w/historian Lloyd Llewellyn-Jones about the rise of Cyrus. Echoes to this day in modern Iranian society.
Mind blown. 🤯
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And with that, 3 years of residency come to an end. It was not easy - so much time away from family, managing sick patients + navigating complex healthcare system. But it laid the intellectual + emotional foundation for the next phase of this journey. Many thanks
@CCF_IMCHIEFS
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Heme/onc fellowship interviews have started rolling in. Let’s get started.
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Never thought I’d be working at the 2nd best hospital in the US. I remember reading Toby Cosgrove’s book “The Cleveland Clinic Way” when I was in the corporate world and thinking “I want to work here one day.” Dreams do come true.
Cleveland Clinic has been named the
#2
hospital in the nation and the
#1
hospital for heart care by
@usnews
.
#BestHospitals
.
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Wow - there are a lot of podcasts about hematology/oncology. For those early in their training (ie. Fellows, Residents, med students) ➡️ highly recommend these. They cover broad topics across tumor types including case presentations, fundamentals of Dx + Rx, recent trials 🧬🩸💊
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Submitted Rank List for [oncology] fellowship. Really, really enjoyed the interview trail. Lots of brilliant PIs + fellows doing exciting research to extend survival + elucidate mysteries of the cancer cell. Now to wait for an algorithm to inform my professional trajectory.
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This has been a week of emotions. Humbled to have worked w/talented, compassionate & ambitious resident colleagues. Folks with diverse intellectual, cultural & professional backgrounds. There will never be a journey as incredible as residency.
@CCF_IMCHIEFS
@ClevelandClinic
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Us
@ClevelandClinic
graduates stick together. So awesome to explore our new institution
@UChicago
together with fellow
@ClevelandClinic
graduate + future gastroenterologist
#ArielSim
. We spent most of our time being lost. Also how do you pronounce “Duchossois”?
@CCF_IMCHIEFS
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Re-reading (5 pages a day) one of my favorite books of all time about cancer. Especially helpful as I head to our leukemia service. Just really really good writing. Kudos
@MikkaelSekeres
.
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MD friends: consider getting an MBA if you have broader ambitions (i.e. hospital management, biotech/pharma, bioentrepreneurship/startups, etc). It's a versatile degree, will broaden your horizon & show you how $$$ + power flow through organizations.
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If you love history, especially how great empires rise & fall ➡️ this is one of the best.
@tweeter_anita
and
@DalrympleWill
have great chemistry as hosts & they bring on the smartest guests. Can’t stop listening. This upcoming series on Iran is timely. 📚
Empires of Iran: From the Rise of Cyrus - and the reigns of Darius and Xerxes 1/4
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It’s finally here!
@DrAnitaRaghavan
& kids have moved back to Chicago! They stayed back in Cleveland for Anita’s work while I moved to Chicago for fellowship. We loved Cleveland & were sad to say goodbye to friends. Life was so easy in CLE. Now onwards to fun times in Chitown!
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A room with a view. I love early mornings on campus before the hustle & bustle of hospital life starts.
@ClevelandClinic
@CCLRI
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Flew back to Chicago tonight & took this video while turning over the lake towards O’Hare. Chicago is beautiful at night.
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There’s been a ton of new data in prostate cancer this year.
These 2 Reviews do a great job of synthesizing & integrating it into a review of the fundamentals of both:
🧬 basic tumor biology and
💊 clinical SOC
Clearly written with helpful figures & tables.
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After years in the corporate world (where PowerPoint was medium of persuasion), I’ve had to re-learn the academic peer review process. Thrilled to be selected for
@ASCO
’s Editorial Fellowship where I’ll work w
@JCO_ASCO
editors to understand behind-the-scenes.
@UCHemOncFellows
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☕️💊🔥Join if you can at
@UCCancerCenter
I’ll be presenting treatment of metastatic prostate cancer, role of AR signaling + related mechanisms of resistance & results of our phase 1 (IIT) trial of combined AR antagonist (enzalutamide) & GR antagonist (relacorilant) in mCRPC.
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Working nights in the COVID ICU this week. This thing is very real & it’s back. Be safe everyone.
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Seriously, I cannot wait to be an oncologist. Been dreaming of it since I was 16. Took a detour to get here - but still got here.
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Hey
@tweeter_anita
&
@DalrympleWill
➡️ I was so blown by your podcast series ⚡️🔥 on the Ottoman Empire that I had to buy this book by
@MarcDavidBaer1
. What a epic tour through history that was. This book is first on my summer reading list. Kudos.
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In 2013, I became suddenly unemployed. All that free time gave me the mind space to think about what I really wanted out of life. It kicked off a 7-yr journey to becoming a doctor. I love this job. Sometimes, you have to lose something to gain something even bigger.
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Getting ready for another fellowship interview. Love the virtual format. Also love those long awkward pauses w/15 people on the screen - and everyone is waiting for a resident to ask a question...
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I can’t get over this timeline of targeted therapy approvals in NSCLC. What incredible progress in drug development - built on decades of basic sciences research. IO timeline is impressive too but lacks sheer density of novel agents.
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Haven’t been this excited about an area of drug discovery in a while. Most comprehensive, clearly written & timely Review. Breath of topics is impressive: CAR designs + strategies to optimize Ag selection & overcome immunosuppressive TME.
@NatRevDrugDisc
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In every
@NCCN
guideline document, there is a highly readable, current & comprehensive overview of that tumor type (after the patient flow algorithms). It’s become my new starting point when learning about a new tumor type or to understand specific aspects in detail.
#FellowLife
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Just spent an epic morning in melanoma clinic with
@FunchainMD
learning about tumor biology, IO, IRAEs & most importantly - how to communicate w patients.
@FunchainMD
is the ultimate clinician, educator & human being. I aim to emulate her.
@ClevelandClinic
@CCF_IMCHIEFS
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If you treat RCC w/bone mets, our paper describes outcomes on ipi/nivo. 1st published retrospective analysis in this subset of pts. Many thanks to collaborators at
@ClevelandClinic
@DukeCancer
@VUMC_Cancer
. .
@TargetedOnc
@SpringerNature
. Brief Tweetorial:
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@MrDanZak
My 2-year-old has the discipline to wear a mask for 1.5 hrs. Surely fully grown adults can match that resolve.
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Fellow life is busy w/research, clinic, didactics & more.
It feels like flying a plane while building it ➡️ learning basics of each tumor type while staying abreast of latest data.
Podcasts are a great way to do both. I’ve found these to be most helpful in my education 💊🧬🩸
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I can’t wait to start oncology fellowship. I get to read + think about cancer all the time: biology, targets, therapies, trials. Most importantly - build longer-term relationships with patients & their families. Let’s go.
#JulyCometh
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This story points to the deeper issue: exploitation of the Resident workforce. An MBA grad earns >$150K/yr & learns on the job. A Resident does the same but works 70-80 hr/wk, saves lives, sacrifices family time - all while earning $60K/yr. Why is this ok?
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Wow - finally started watching malignant heme lectures from
@ASH_hematology
’s “2021 Hematology Review Series" - highly informative, practical & must-read for 1st yr Fellows. I use their slides on leukemia service.
@UCHemOncFellows
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4
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The scope of what MDs can do is changing 🔥. Thrilled to be selected as a
@UChicago
Innovation Fund Associate: a 1-year (part-time) program run by
@polskycenter
for
@UChicago
trainees to serve as Venture Capital Associates w/ George Shultz Innovation Fund.
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I’ve got podcasts on oncology, biotech, business piling up - but I can’t stop listening to Season 2 of “Empire”. A sweeping tour thru the Ottoman Empire - fall of Constantinople, battles, social mores, coffee. Love the hilarious back-and-forth b/ween
@tweeter_anita
@DalrympleWill
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It’s a beautiful Friday morning here at the
@ClevelandClinic
. Will miss this institution & colleagues.
@CCF_IMCHIEFS
@CCLRI
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I have tremendous respect for basic scientists. It takes a lot of grit, dedication and most importantly - imagination. They are building the foundation upon which all of medicine rests.
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Are you even a Midwestern kid if you don’t own your own
@JohnDeere
tractor & trailer?
#MidwesternLife
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Check out our poster at ASCO GU: collaboration
@UCCancerCenter
&
@VUMC_Cancer
(
@KSchaffer17
&
@brian_rini
) analyzing n=146 mCRPC pts who received SOC Lu177 (PLUVICTO).
💊Our cohort received fewer cycles of Lu177, higher rate of anemia (25% required RBC tx) & lower PS vs VISION
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Found a great new PCP. He’s a little young but has excellent bedside manners. Also, he likes cookies & watching PJ Masks.
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If you also have ridiculously long commute (>2 hr a day) & love history ➡️ check out newish podcast “Empire”. Indepth discussions w/historians about rise & fall of empires. 1st episodes are about East India Company & the Raj. Hard to stop listening.
@tweeter_anita
@DalrympleWill
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When you live together but also start working at the same institution. Congrats to
@DrAnitaRaghavan
for joining
@UChicago
Pediatrics as an Attending Physician. She’s coming back “home” - having done undergrad & pediatrics residency at
@UChicago
@ComerChildrens
.
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It’s a beautiful summer day in Chicago today. Life is good.
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I absolutely love being a doctor. Best decision I ever made.
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When your junior Residents decorate the work room and get you a giant chocolate cake. Acts like these give you an honest glimpse of the culture of an institution. Last day in IM clinic (ever) draws to a close.
@Ashruta_Patel
@TGFlynn_III
@CCF_IMCHIEFS
@ClevelandClinic
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1
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Writing a Review is an excellent way of learning a field. PCa is rapidly evolving with novel therapeutic approaches & combos + insights into tumor biology. Many thanks to
@NimaSharifiMD
for his continued thought leadership + mentorship.
@CCLRI
@CleClinicUro
@ClevelandClinic
Great work
@KunalDesaiMD
& Jeff McManus on leading the effort to write this review on hormonal therapy for prostate cancer in
#EndocrineReviews
! Thank you
@DanielJDrucker
for your invitation!
@EndoSocJournals
@TheEndoSociety
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Wow wow wow. This year’s graduating hematology/oncology Fellows from
@ClevelandClinic
#TaussigCancerCenter
had phenomenal placements -
@DanaFarber
,
@bethisraellahey
/
@harvardmed
,
@UHhospitals
&
@ClevelandClinic
. Kudos to
@jamecancerdoc
& team.
Congratulations to our outstanding fellows from
@ClevelandClinic
#CleClinicCancer
proud of you!!fortunate to continue to work with
@MeenaSadapsMD
@kgnairmd
@siddharthkunte
at
@CleClinicMD
@irisyshengMD
and Dr. Sussman heading to Boston! Dr. DeSouza staying in Cleveland!
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My 3-year-old just graduated from Montessori school & next week, I graduate from IM residency. You’re never too young (or old) to invest in your education. Keep learning. Always.
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Kudos to
@NimaSharifiMD
for his scientific leadership in helping make
@ClevelandClinic
a Center of Excellence in GU malignancies. A thoughful mentor + personal role model for me.
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Omg my Attending
@abbyCCim
& team just threw a 60th birthday party for a patient. We are having too much fun.
@CCF_IMCHIEFS
@ClevelandClinic
🎂🎈🥇🥳😷
#COVID19
got U down on your 60th birthday?
@CleClinicMD
#CCIMRP
gen med team has you covered! No one celebrates their 60th birthday 🍰 🎁 alone on our watch!! We brought the party to him! Balloons🎈& 🧁 for all! Can’t say his tears didn’t make us tear up too!
#ProudPD
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One of the main reasons I chose
@ClevelandClinic
for IM residency was the excellent track record of Fellowship placement. They continue to deliver. Kudos.
@CCF_IMCHIEFS
🔥💥
Could not be more proud of all our residents who matched into fellowship this past week week!!
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0
1
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I have today off & planned to read, write, study. Instead, took my son to school, played w/car-cars & read his fav comic book (Tintin) all morning. I’d say it’s been a productive day.
5
0
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Congrats to
@SuhaAbushamma
for joining
@ClevelandClinic
as an Attending! She may not recall this but she was my first-ever senior on my first rotation as a (terrified) Intern. She helped me replete my first potassium & taught me so much more. Kudos.
@CCF_IMCHIEFS
👉🏽👉🏻👉🏿Thrilled to announce that Dr. Suha Abushamma (
@SuhaAbushamma
) will join
@ClevelandClinic
#WeTheTeamIBD
👍 as a staff member in summer 2023! Amazing addition and BIG win. Welcome!
@MRegueiroMD
@JPAchkarMD
@JessPhilpottMD
@ManuelBragaMD
@tqaziMD
@IBDBen
@HolubarStefan
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Just finished my first [virtual] fellowship interview. I like this format a lot. Felt just as intimate & more relaxed to be honest. Plus travel time + $$ saved. I hope it’s the new normal...
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@RepJayapal
Huzzah
@RepJayapal
appreciate the accountability you have brought to hearings this week. Keep up the good fight.
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When Attendings ask what your 5, 10, 20-year plans are but you’re thinking about lunch.
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Unsung heroes of the COVID19 crisis: respiratory therapists.
1
1
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I've noticed that someone I admire
@abbyCCim
reads widely & extensively. I love to read & finally have more time in PGY3 yr. Inspired to set a goal of 2 non-medical books a month. Topics include history, politics, business, biography.
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1
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Happy Diwali & Happy Halloween! A busy day that brought 2 costume changes & lots of sugary treats.
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It’s a beautiful Sunday morning in Chicago. Life is good.
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Fellow bringing Resident on board for exciting new research project that requires chart review for only 400 patients.
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