@jfais20 are they still developing ACR-368 for ovarian cancer? Most recent news appears mainly focused on endometrial.

@paulpetertak @CandelTx truly amazing work! I look forward to the data for CAN-3110 in glioma later this year.

@jeremyj0916 @BowTiedBiotech true. And also pretty odd that LLY would go with a competing drug if the data presented for rez was good (although it appears the data may be been misinterpreted by Lilly).

@richtrades100 what happened to development of bexotegrast for PSC? It is no longer noted on the pipeline portion of their site.

@JohnFitisoff I really like the data $CMMB has for CM-101 in PSC, which has no FDA approved treatment.

@NIH good!

@longonlybio @BioWino will have to look at neurogene a bit further. My understanding was that $TSHA therapy was well-tolerated and effective without safety signals. $NGNE with some efficacy but safety concerns.

@Sports_bios agree this is a high-risk space. Neuropsych very difficult area though the data for psychedelics is pretty good.

@BioWino interesting. I wonder when we'll get the next update from them.

$MBIO company needs to focus on MB-109 and ditch autoimmune which is a crowded space. Their science with IL13Rα2-targeted CAR T cell therapy in glioblastoma is promising. Maybe sell their assets to a company which can take this treatment to the finish line.

@Joshthe3rd_ do they have a plan for their allogenic platform?

@seedy19tron agree data for REC-994 is underwhelming. They are an "AI" company posing as biotech. Hopefully I am proven wrong.

@pawcio2009 how are they distinguishing themselves from $BNTX's BNT113?

@volatileincome @DmitryKovalchuk CAR-T as a whole has been suffering. I think there's doubt about TAM and manufacturing costs. $AUTL has a promising pipeline including T-cell lymphoma and neuroblastoma.

@BiotechObserver wonder why $MRSN is up if $PFE stated that B7-H4 lacks convincing efficacy.

@JohnFitisoff do you have any thoughts for $CMMB versus $PLRX's bexotegrast? Both with decent data in PSC, for which we do not have an FDA-approved treatment.

@EricTrump thanks for the suggestion. I bought some ETHA.

@AnExpertOne1 are we expecting news soon?