Juleen R. Zierath
@JuleenRZierath
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Professor of Physiology, Lifelong Athlete, Member of Nobel Assembly @karolinskainst , KVA @ScienceAcad_swe , & @KeystoneSymp Board - Past EASD President @EASDnews
Joined February 2015
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Ok! This happened today ! I am officially Knight/Lady/Dame
I have been appointed Knight of the Riddersson Order of the Dannebrog!
So grateful to
#Denmark
and so very cool! 🙏🏻
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Atlas of exercise metabolism reveals time-dependent signatures of metabolic homeostasis.
Canonical & novel timed exercise-specific metabolites were revealed using a systems biology approach. Sky displays the timed nature of exercise Art by Mattias Karlen
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Our latest
Exercise metabolism and adaptation in skeletal muscle | Nature Reviews Molecular Cell Biology
A great collaboration with
@JonoSmith01
@KevinMurachPhD
@DyarKen
👍
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Atlas of exercise metabolism reveals time-dependent
signatures of metabolic homeostasis is now online
@Cell_Metabolism
Great collaboration w/
@s8shogo
@DyarKen
@treebak
@lutter_dominik
@sassonecorsilab
@srp_diabetes
@Metabolcenter
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Celebrating the extraordinary life of my dear friend Paolo Sassone-Corsi
@sassonecorsilab
He was an extraordinary talent and will be missed! Paolo had a brilliant mind & boundless energy/enthusiasm for research into circadian biology. A great mentor to many in the field.
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Today is the day the Nobel Prize in Physiology or Medicine is announced. Stay tuned!
@NobelPrize
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Our latest review on exercise metabolism!
Great collaboration w/ Stephen Ashcroft, Ben Stocks & Brendan Egan!
@Metabolcenter
@srp_diabetes
@Cell_Metabolism
Exercise induces tissue-specific adaptations to enhance cardiometabolic health
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Afternoon exercise is more efficacious than morning exercise at improving blood glucose levels in individuals w/type 2 diabetes-a randomised crossover trial
@DiabetologiaJnl
@MSavikj
@DrBMGabriel
@JonoSmith01
@marie_bjornholm
@AnnaKrook_KI
@HarrietWallberg
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Honored to be recognized as the recipient of the 2021 Harold Rifkin Award for Distinguished International Service in the Cause of Diabetes from the American Diabetes Association!!
@ADA_DiabetesPro
looking forward to ADA’s 81st Scientific Sessions!!
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An amazing celebration of the 2023 Nobel Laureates. Concert house in Stockholm tonight!
Such a spectacular evening!! 🙏🏻Celebrating science and humanities!
@NobelPrize
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Super excited this paper
@NatureComms
is FINALLY out! A comprehensive analysis of exercise-induced miRNAs in skeletal muscle by
@AnnaKrook_KI
& team
@srp_diabetes
Endurance exercise training-responsive miR-19b-3p improves skeletal muscle glucose metabolism
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Extremely grateful for this amazing honor! 🙏🏻 Grateful for all the amazing colleagues I have had the opportunity to work alongside over the years! See you in Madrid!
Congratulations to Juleen Zierath who is the recipient of the EASD-Novo Nordisk Foundation Diabetes Prize for Excellence 2024! 👏
@JuleenRZierath
receives the award at
#EASD2024
in Madrid to recognise her outstanding achievements in
#diabetes
#research
.
@novonordiskfond
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Great team effort!
Exerkines in health, resilience & disease | Focus on the potential role of exerkines in driving the benefits of exercise, such as preventing & mitigating disease, promoting health & increasing resilience
@NatureRevEndo
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Time of Exercise Specifies the Impact on Muscle Metabolic Pathways and Systemic Energy Homeostasis - time of day is a critical factor to amplify the beneficial impact of
#exercise
on metabolic pathways within skeletal muscle & systemic energy homeostasis
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Train like an athlete: applying exercise interventions to manage type 2 diabetes Latest review together with
@MSavikj
online today
@DiabetologiaJnl
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Metabolism in Action is back in action!
The link to conference website here:
Call for abstract submissions is now open / deadline is 1st of June 2022
See you there!!
@Metabolcenter
@srp_diabetes
@novonordiskfond
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Honored to receive this support from the ERC Advanced Grant program! Our work will bring together researchers from
@Metabolcenter
and
@srp_diabetes
with a focus on type 2 diabetes
📣 Good news today for 255 outstanding research leaders who have been offered ERC Advanced Grants.
The new funding, worth nearly €652 million, is part of the 🇪🇺EU’s
#HorizonEurope
programme.
Read more 👉
#ERCAdG
#FrontierResearch
@EUScienceInnov
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Loving this Cell Press conference on Exercise Metabolism!
@CellCellPress
@Cell_Metabolism
#Exmet2024
Thanks to my team
@Metabolcenter
for designing this poster!!!
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Honored to receive the Erhoff Prize today. Many thanks to my colleagues and associates throughout the years. 🇩🇰 🇸🇪
@Metabolcenter
@srp_diabetes
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Excited to share our latest work 👇👍
@ScienceAdvances
Great team effort!
@DrBMGabriel
@_AliAltintas_
@srp_diabetes
@Metabolcenter
Disrupted circadian oscillations in type 2 diabetes are linked to altered rhythmic mitochondrial metabolism in skeletal muscle
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Extremely grateful to
@AmDiabetesAssn
for the recognition. I have enjoyed serving the diabetes community over the last decades
@EASDnews
@DiabetologiaJnl
@EUDiabetesForum
Real pleasure to interact w/scientists, clinicians, & people with diabetes!
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Exercise/Physical Activity in Individuals with
Type 2 Diabetes: A Consensus Statement from
the American College of Sports Medicine
Honored to contribute w/several esteemed colleagues to this report now out on
#exercise
&
#diabetes
@MSSEonline
@ACSMNews
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Happy news!
Atlas of Exercise Metabolism Reveals Time-Dependent Signatures of Metabolic Homeostasis
From editor: I am delighted to say "congratulations" on your paper, which is now accepted at Cell Metabolism! In the meantime, you can continue citing the paper as "In Press".
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Latest from
@AnnaKrook_KI
@DolletLucile
congratulations!
Exercise-induced crosstalk between immune cells and adipocytes in huma...
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Submitted a review & revised a manuscript… one more manuscript is a “work in progress” 😉 New data is hot off the mass spec… Just grateful for the incredible team of students, post-docs & collaborators! Now it’s time to have a little down-time- even if just for the weekend! 👍
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Ten International Postdoctoral Fellowships in Metabolism - Novo Nordisk Foundation Center for Basic Metabolic Research
@Metabolcenter
@UCPH_health
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Many thanks once again to EASD
@EASDnews
for this tremendous honor! The Claude Bernard Medal arrived the mail today! Thanks to EASD President
@SDelprato
for your kind words! Looking forward to
#EASD2022
to celebrate in person together w/members of
@srp_diabetes
@Metabolcenter
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Seasonal light hours modulate peripheral clocks and energy metabolism in mice
@Cell_Metabolism
Our latest from
@LewinSmall
& colleagues
@Metabolcenter
@treebak
@Romain_Barres
Photoperiod modulates energy metabolism & phase shifts peripheral clocks
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Thanks
@NobelPrize
for the opportunity to share some views!
#NobelPrize
How can you be awarded a Nobel Prize?
Go behind the scenes of the Nobel Prize in Physiology or Medicine in our interview with medicine prize awarder Juleen Zierath,
@JuleenRZierath
#NobelPrize
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Check this out! 👇
We are delighted to announce the
@CellSymposia
:
#Exercise
#metabolism
, will take place May 5-7, 2024, in Lisbon, Portugal
#Exmet2024
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Our latest
@DiabetologiaJnl
"Branched-chain amino acid metabolism is regulated by ERRα in primary human myotubes and is further impaired by glucose loading in type 2 diabetes"
@AnnaKrook_KI
and team!
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Is It Better to Exercise in the Morning or Evening?
There may be an optimal time to exercise for our metabolism- but “any time” it is always a good time to exercise!!
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Out fishing with Mom today! 82 years young! 💪🏻👍 Enjoying the Swedish archipelago!! Happy summer all!! 🎣🐠
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Never underestimate the importance of mentors! I am truly grateful for the opportunity to have been trained by one of the greatest of our time! Professor David L. Costill!
@BallState
@HPLBallState
#exercise
A legend in the field of exercise physiology!
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Plasma Metabolome Profiling of Resistance Exercise and Endurance Exercise in Humans
Congratulations
@ClemmensenC
and team!!
@Metabolcenter
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Atlas of Exercise Metabolism Reveals Time-Dependent Signatures of Metabolic Homeostasis
@SSRN
@cellpressnews
Our data add new perspectives about how tissues independently and collectively respond to exercise at different times of the day. Sneak Peek
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My partners in “glucose transport” crime! Celebrating science with my longtime pals- Amira Klip and Barbara Kahn “Girls on the go”
#stem
#WomenInScience
#diabetes
#metabolism
@APSPhysiology
@AJPEndoMetab
@FASEBorg
#ExpBio
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Just learned that the Endocrinology and Metabolism Section of the American Physiological Society has selected me for the 2019 Solomon A. Berson Distinguished Lectureship Award! I am extremely honored!
@APSPhysiology
#metabolism
@MMK_research
@Metabolcenter
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Check out our latest review. Another great collaboration with my colleague
@DrBMGabriel
Covering topics related to
#exercise
#muscle
#Diabetes
and the Molecular Circadian Clock.
New content online! Circadian rhythms and exercise — re-setting the clock in metabolic disease
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2021 Nobel Prize Ceremony is about to start! Congratulations to all the Laureates!
@NobelPrize
#NobelPrize
Greeting from Stockholm!
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Our latest- Transcriptomic profiling of skeletal muscle adaptations to exercise and inactivity
@NatureComms
| Thanks to
@NicoPillon
@DrBMGabriel
@BlueSpotScience
@AnnaKrook_KI
& entire team!
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John O. Holloszy (1933–2018) “Father of modern Exercise Physiology”
obituary online
@Cell_Metabolism
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Morning! Today is Friday- in case you need a reminder 😉
I find during this pandemic - every day feels the same — & I easily forget what day of the week it is.
Looking forward to a zoom-free 48 hrs -
Have a nice weekend & remember to take time for yourself & family/friends! 👍
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In print!
@DrBMGabriel
and I review the literature regarding diurnal skeletal muscle metabolism and the interaction with exercise bouts at different times of the day to combat metabolic disease. Timing matters!
#exercise
#muscle
#physiology
In our latest issue:
@JuleenRZierath
&
@DrBMGabriel
review
#circadian
rhythms and
#exercise
— re-setting the clock in
#metabolic
disease
#CircadianRhythms
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Perfect day! Last year I missed the annual ski trip because I was down with COVID! This year I am back on track! Happy trails!
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Any exercise is better than no exercise!! But... sometimes timing matters! Our study into this question in people with type 2 diabetes in
@DiabetologiaJnl
plus work by
@SchrauwenP
is discussed by
@GretchenReynold
@nytimes
The Best Time of Day to Exercise
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When is the best time to exercise? Generally the best time to exercise is anytime you can, but there are some time-of-day responses! Thanks to
@BBC_Reel
for the opportunity to discuss this topic and our new work from
@srp_diabetes
@Metabolcenter
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Great news to wake up to!
“I am pleased to inform you that your manuscript "Three Weeks of Interrupting Sitting Lowers Fasting Glucose and Glycemic Variability, but not Glucose Tolerance, in Free-Living Women and Men with Obesity," has been accepted!”
@AJPEndoMetab
👍
@JonoSmith01
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Our recent review The Limits of Exercise Physiology: From Performance to Health w/
@DrBrendoGabriel
@Cell_Metabolism
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Transcriptomic Profiling of Skeletal Muscle Adaptations to Exercise and Inactivity
Great collaboration!
@NicoPillon
@DrBMGabriel
@BlueSpotScience
@DolletLucile
@JonoSmith01
@LauraSardon
@javi_iup
@AnnaKrook_KI
Our preprint is now online
@biorxivpreprint
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Happy
#WomenInScienceDay
!
Happy
#WomenInScience
Day! 👩🔬👩🚀 Let’s smash stereotypes, defy gender bias and defeat discrimination that holds women and girls back in Science, Tech, Engineering and Math.
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Had a great meeting at Harvard Medical School! Diabetes was in the focus. Caught up with Ron Kahn, Amira Klip, and Barbara Kahn- We had many great discussions about the pathophysiology of Diabetes and accelerating science forward to make an impact!
#diabetes
#metabolism
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Check out this new preview on Healthy Aging by
@s8shogo
and Sam Bennett! 👍
Metabolic elasticity: A new measure of age: Online
@CellPressNews
@Cell_Metabolism
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Our new research facility
@karolinskainst
is officially open! Biomedicum is truly state-of-the art!
Inauguration of Karolinska Institutet's new research facility Biomedicum
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Seasonal light hours modulate peripheral clocks and energy metabolism in mice: Cell Metabolism
Published today! 🍾
@Cell_Metabolism
@CellCellPress
Congratulations
@LewinSmall
and team!
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Lifelong exercise 👍💪👇 !!
Lifelong exercise delays the major consequences of aging.
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Exercise timing influences multi-tissue metabolome and skeletal muscle proteome profiles in type 2 diabetic patients – A randomized crossover trial - Latest from
@MSavikj
@ben_stocks1
@s8shogo
Kenneth Caidahl
@AnnaKrook_KI
@atul_deshmukh1
@HarrietWallberg
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I had the honor of presenting the 2021 Claude Bernard Lecture "Sending the Right Signals – How Exercise Keeps the Rhythm in Metabolism" at the Virtual EASD Meeting
@EASDnews
this week. I highlighted the work of this AMAZING group! Thx team!
@srp_diabetes
@Metabolcenter
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Check out this latest edition of Cell Metabolism w/focus on exercise!
We were happy to contribute w/ cover suggestion for this, as well as a review: “Exercise induces tissue-specific adaptations to enhance cardiometabolic health”
@Cell_Metabolism
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Super honored to be amongst this group!
#IBEC2022
was a fantastic meeting! I learned to much and really enjoyed the many poster and oral presentations. Congratulations to all!!
The winners of the IBEC Honor Award. Left to right: Mark Tarnoplosky (2015),
@proferikrichter
(2012), Frank Booth (2006),
@JuleenRZierath
(2018) and Marc Hargreaves (2022)
#IBEC2022
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This review is based on my lecture at the ADA’s 79th annual Scientific Sessions entitled "Major Advances and Discoveries in Diabetes. I highlight advances in basic science, w/insight into how these breakthroughs challenge the field to move into the clinic.
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News that made my day...! “I am pleased to inform you that the revision of your manuscript entitled "Quantitative Phosphoproteomic Analysis of IRS1 in Skeletal Muscle from Men with Normal Glucose Tolerance or Type 2 Diabetes: Case-Control Study" is now acceptable for publication”
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Congratulations Thue!
@Thue_Schwartz
Innovation Award 2023
@uni_copenhagen
goes to professor Thue W. Schwartz, Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health & Medical Sciences.
@Metabolcenter
@UCPH_health
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Time-restricted feeding alters lipid and amino acid metabolite rhythmicity without perturbing clock gene expression |
@NatureComms
great collaboration w/
@JohnAHawley
@sassonecorsilab
@Romain_Barres
Leo Lundell Evelyn Parr
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Enjoying the latest developments in metabolism/obesity/diabetes research at the joint
#KSBioenergetics23
#KSAdipose23
meeting
@KeystoneSymp
! Great science and great views!
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Backstage at
#NobelPrize
ceremony w/Sara Snogerup Linse and fellow Medicine Committee member Maria Masucci
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New clinical translational study to assess if exercise-induced reductions in visceral adipose tissue mass in humans are mediated by IL-6
Exercise-Induced Changes in Visceral Adipose Tissue Mass Are Regulated by IL-6 Signaling: A Randomized Controlled Trial
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Honored to receive the “Honour Award” from the International Research Group on Biochemistry of Exercise
#exercise
#physiology
#ibec
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Our latest
@biorxivpreprint
Branched-Chain Amino Acid Metabolism is Regulated by ERRα & is Further Impaired by Glucose Loading in Type 2 Diabetes
Metabolic inflexibility in T2D impacts BCAA homeostasis & BCAA genes via a PGC-1α/ERRα-dependent mechanism
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Exercise timing influences multi-tissue metabolome and skeletal muscle proteome profiles in type 2 diabetic patients – A randomized crossover trial! w/
@MSavikj
@ben_stocks1
@atul_deshmukh1
Kenneth Caidahl
@AnnaKrook_KI
&
@HarrietWallberg
@karolinskainst
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Honored to serve on the 2018 Nobel Prize Committee for Physiology or Medicine
#NobelPrize
#Nobel
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Looking forward to the Presidential Address from Prof. Stefano Del Prato
@SDelprato
Tuesday, 28 Sep, 10:00—11:15
@EASDnews
Thereafter I deliver the 53rd Claude Bernard Lecture and highlight work related to exercise and metabolism
#EASD2021
#diabetesawareness
#exercise
#metabolism
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Our latest: Three wks of interrupting sitting lowers fasting glucose & glycemic variability, but not glucose tolerance, in free-living women & men with obesity
@JonoSmith01
@MSavikj
@AJPEndoMetab
via
@NYTimes
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Coming soon from
@CSHL
A review series on The Biology of Exercise Edited by
@JuleenRZierath
@DrMJoyner
@JohnAHawley
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Together w/
@NicoPillon
@profsmarshall
& Ruth Loos we share views on genes, environment & precision medicine in our recent review "Metabolic Consequences of Obesity and Type 2 Diabetes: Balancing Genes and Environment for Personalized Care"
@CellCellPress
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CBMR International Postdoctoral Program – Open Call!
University of Copenhagen
@Metabolcenter
is
currently recruiting 5 international postdoctoral fellows to the Novo Nordisk Foundation Center of Basic Metabolic Research. 👇
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Grateful for the opportunity to thank Speaker Pelosi directly for all her incredible work to put people over politics and honoring democracy! 🙏🏻
@SpeakerPelosi
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Integrative Biology of Exercise: Multiple organ systems are affected by exercise - The beneficial effects numerous!
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Looking forward to hosting this meeting on Exercise Biology! 👇👍
Check out the speakers for the
@CellSymposia
:
#Exercise
#metabolism
, includes Bente Klarlund Pedersen
@UCPH_Research
@benteklarlundp
#Exmet2024
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Our collaborative work with
@diabetesmaster
@labs_mann
@AnnaKrook_KI
A Cell-Autonomous Signature of Dysregulated Protein Phosphorylation Underlies Muscle Insulin Resistance in Type 2 Diabetes:
@Cell_Metabolism
#diabetes
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Disrupted circadian core-clock oscillations in Type 2 Diabetes are linked to altered rhythmic mitochondrial metabolism
#diabetes
Our latest collaboration with
@DrBMGabriel
@AliAltintas666
@JonoSmith01
@LauraSardon
@kaesser
@Romain_Barres
@ryden_mikael
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All work and no play is no way to go! Taking the opportunity to enjoy the day and the fantastic weather on
#InternationalDayOfWomenAndGirlsInScience
#WomenInStem
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New from the team:
Metabolic plasticity and obesity-associated changes in diurnal postexercise metabolism in mice.
Biological rhythms and diurnal metabolic flexibility are impaired in obesity.
Great collaboration between
@srp_diabetes
@Metabolcenter
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Excited to return to my undergrad university!
I will be awarded an honorary doctor of science degree during spring commencement at the University of Wisconsin-River Falls.
@UWRiverFalls
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Healthy Weight Loss Maintenance with Exercise, Liraglutide, or Both Combined | NEJM
@UCPH_health
A strategy combining exercise and liraglutide therapy improved healthy weight loss maintenance more than either treatment alone.
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Dissertation day for Jon Smith!
@JonoSmith01
Jon defends his PhD work on “Skeletal Muscle Responses to Physical Activity in Health and Metabolic Disease” his opponent is Professor Marcas Bamman
@MarcasBamman
Defense is now underway
@karolinskainst
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New resource related to muscle biology and metabolism from our team!
Not all skeletal
#muscle
models are equal. Our latest publication in
@AJPCellPhys
shows that L6, C2C12 and primary human myotubes have important differences in their
#metabolism
and
#transcriptome
.
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Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention | Nature Genetics
Thanks to Marcel den Hoed and team for this excellent collaboration!
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Super happy to spend this summer vacation with my mom here in Sweden for her annual visit. Today we had a great fishing tour in the Stockholm Archipelago and caught 55+ pike and perch! 🎣🐟 👍
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Always a pleasure to receive good news! Congratulations to the team
@NicoPillon
@LauraSardonPuig
@_AliAltintas_
@AnnaKrook_KI
@DrBMGabriel
@prasadkamble1
and colleagues
A heroic study! Am delighted we got to the finish line! 👍🎉🍾
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Together with
@DolletLucile
we discuss the adaptive response of fat cells to exercise and diet. We review the literature related to time-restricted diets/exercise-timing/adipocyte biology and share thoughts on future research questions.
#metabolism
#exercise
#diet
'Interplay between diet, exercise and the molecular circadian clock in orchestrating metabolic adaptations of adipose tissue' from
@JuleenRZierath
@DolletLucile
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Just out from the team today! Congratulations Logan Pendergrast and colleagues!
Time of day determines postexercise metabolism in mouse adipose tissue | Proceedings of the National Academy of Sciences
@PNASNews
@karolinskainst
@Metabolcenter
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