James Gallagher
@James_Gall_
Followers
90
Following
273
Statuses
53
Dynamic catalysis and nonequilibrium chemistry. Postdoc @Toste_Group at @UCBerkeley, PhD @ProfDaveLeigh at @OfficialUoM.
Joined April 2022
Out now in @NatureSynthesis, we drive an endergonic Diels-Alder reaction energetically uphill by chemical fuelling. Reminiscent of anabolism in biology, we hope that an understanding of endergonic synthesis will help expand the chemist's toolbox.
3
7
66
@EPenocchio @DeanAstumian Cool! Ofc Hammond not always relevant, but it nicely shows that kinetic asymmetry /can/ be a function of the power stroke. So "x doesn't matter y does" is not very satisfying when y = f(x)!
0
0
2
@DeanAstumian An interaction that significantly lowers an activation barrier will also significantly lower the energy of the ground state (given Hammond). Perhaps the binary of kinetic asymmetry vs. power stroke is not useful if in many cases one depends on the other.
1
0
1
RT @RSC_MASC: Many excellent nominations were received, and the judging panel decided to award two Highly Commended awards to Lei Chen (Uni…
0
1
0
A pleasure to Preview recent work by @EPenocchio, @DeanAstumian and @giuliosflask for @Chem_CP. Life is defined by its compartments, find out how 'thinking inside the box' helps us to understand nonequilibrium systems here:
1
3
21
1
0
1
RT @NatureSynthesis: June issue live🥳 Mirror-image cyclodextrins Endergonic synthesis On-liquid-gallium surface synthesis Isolation of a pe…
0
9
0
RT @benjamino_acid: Finally, after 5 years working on it with @StefanBorsley and @ProfDaveLeigh, here is our review on ratchet mechanisms i…
0
14
0
RT @StefanBorsley: Five years in the making with @benjamino_acid and @ProfDaveLeigh! Out now in @angew_chem, find out how to give chemistry…
0
22
0
RT @NatureSynthesis: Now online: News & Views on the Article by @enzoolivieri4 @James_Gall_ @AlexBetts95 @Toufic_Mrad @ProfDaveLeigh at @U…
0
13
0
RT @benjamino_acid: Very happy to share the first article from my postdoc with @leonard_prins, "A Minimalistic Covalent Bond-Forming Chemic…
0
7
0
RT @ChemistryWorld: Taking inspiration from synthetic biology and using a ratchet mechanism to drive the transformation, chemists have repo…
0
8
0
@EPenocchio @enzoolivieri4 @AlexBetts95 @Toufic_Mrad @ProfDaveLeigh Thanks Emanuele, and made all the better with yours and @benjamino_acid's input!
0
0
3
RT @NatureSynthesis: Now online and open access: Article by @enzoolivieri4 @James_Gall_ @AlexBetts95 @Toufic_Mrad @ProfDaveLeigh at @UoMCh…
0
5
0
thank you to @enzoolivieri4, @AlexBetts95, @Toufic_Mrad and @ProfDaveLeigh. It's been a lot of fun playing around with commercial materials in a total synthesis group!
0
0
3
Ratchets have mainly been used in molecular machinery to accomplish directional motion (an energetically unfavourable process). Here we show that chemical reactions can also be directionally biased, hopefully opening the door to lots of exciting new reactivities.
0
0
1