Genomic Technologies Group
@GenTechGp
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Genomic Technologies Group // The Garvan Institute of Medical Research // Australia's leading long-read sequencing service // Enquiries: [email protected]
Joined August 2020
Check out the excellent line-up of speakers we have for the @GarvanInstitute Long Read Research Symposium day It is FREE to come along - this November 7th. Reserve your spot
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Not long now until the @GarvanInstitute Long Read Research Symposium on November 7th. We will have talented speakers covering the advantages of both @nanopore and @PacBio data Only a few spots left - don't miss out! 💃
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Cut your Nanopore raw data files in half with our new compression method ex-zd. Thanks @Hasindu2008 for leading this project 🧬
Introducing ex-zd, a lossless+lossy signal compression for @nanopore signal data. While lossless can only save about 1-3% over vbz, lossy can cut the file sizes by almost half with no noticeable impact on basecalling or methylation calling accuracy.
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@mprous1 @Hasindu2008 @nanopore That’s a good point, however we don’t think this will happen because the bits that are being removed in our 3-bit-reduction appear to encode noise, not signal (see fig 2a). We speculate that if the basecallers were retrained on bit-reduced data they may even perform better.
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We are hosting a Long Read Research Symposium at @GarvanInstitute ! Our talented speakers will cover the advantages of both @nanopore and @PacBio data. Join us to find out what long reads could do for you 🧬
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@ClarksysCorner Two papers that sat with them for up to 6 months with nothing happening, and no responses to emails. One did end up going to review and eventually published, the other rejected. Complete shambles, and have heard others with similar stories there.
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@Stoibs11 @hiruna72 @Hasindu2008 Hiruna can elaborate, but also pls take a look at SupNote3 for more detailed explanation of the calculate-offset feature
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@Hasindu2008 @josiegleeson @Psy_Fer_ @nanopore Hi Josie, the UHR we sequenced is actually from Agilent (catalog number 740000), which is from a cell line
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RT @Hasindu2008: Our #slow5curl paper is out! Big projects storing hundreds/thousands of @nanopore signal datasets…
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RT @Manu___Singh: Excited to share our latest work on somatic mutations in celiac disease! We discover expanded T cell clones with somatic…
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RT @FabioItaus: Super excited to share our work on #celiac disease. We discovered T cells carrying somatic mutations which may explain chro…
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RT @nadia_davidson: Want an easy to use and fast error/SNP tolerate grep-like tool? Have complex barcodes or indices to demultiplex from ra…
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RT @bogdanoviclab: Final version of our lamprey epigenome remodeling paper is now out in @NatureComms
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RT @hiruna72: Squigualiser preprint with a bunch of usecases is now available 🔥. Your feedback is appreciated.
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Take a break from worrying about the AllOfUs Umap and check out Squigualiser- our new tool for @nanopore signal data exploration. Great engineering by @hiruna72 and @Hasindu2008 as always 🔥🔥
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