FeigeLab
@FeigeLab
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Translational research on Muscle and Aging biology / NIHS Nestle Institute of Health Sciences / @EPFL Ecole Polytechnique Fédérale de Lausanne
Lausanne, Suisse
Joined June 2019
Exciting translational publication just out @jclinicalinvest on a nutrition screen for #stemcells, #muscle #regeneration and #Aging. Fantastic work from our ex @epflSV student @SaraAncel & great collaborative team from Nestle R&D 🧫💪🏃♂️
Excited to share the discovery of nutrients that stimulate MuSCs during #Aging in @jclinicalinvest 🎉 Very grateful to all fantastic teams @RemiRmounier @GondINMG @Isabscionti and stellar colleagues JorisMichaud PascalStuelsatz @FeigeLab 🙏 #myotwitter
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Converging results on impaired mitochondrial calcium as new hallmark of #aging in neurons and skeletal muscle 🧠 💪
New findings in mice have uncovered a crucial mechanism linking neuronal activity to mitochondrial function, researchers report in Science, revealing a potential pathway to combat age-related cognitive decline. 📄: #SciencePerspective:
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Top altmetrics score 2024: #8🏆✨ @Vinz_Sorrentino, @FeigeLab (@NUSMedicine, @EPFL) and co-authors identify trigonelline as a human metabolite that can be used for NAD+ synthesis and that improves #muscle function in #aging worms and mice 💪🐭
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A message to relay: Sarcopenia is not just any sort of muscle wasting, its the loss of muscle mass AND strength with old age (different from cachexia secondary to cancer/COPD/CKD/CHF or disuse atrophy during immobilization…)
Sarcopenia ≠ low muscle mass Main differences between causes, dysfunctions, and outcomes associated with sarcopenia and low muscle mass👇 #muscle #sarcopenia #Health
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@EricTopol @jclinicalinvest @mattiaquattro Thanks for highlighting our work 🙏 We optimized dose and ratio for supplementation in humans to be 700mg NAM and 19mg B6 (within approved safety limits). And the paper shows only NAM works, not other forms of B3 ! Human RCT results coming soon
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Science based nutrients stimulating muscle stem cells for regeneration and aging 😀 🙏 to all authors, reviewers and editors
Nutrients that stimulate muscle regeneration during muscle recovery and aging! @SaraAncel, Joris Michaud, @FeigeLab & team show nicotinamide and pyridoxine enhance muscle regeneration in aged mice: @GondINMG @GarciaPaulineJ
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@sciqst @Cell_Metabolism @dsb_unipd @linusgaia @KeithMGodfrey Yes olive leaf extracts with clinically active doses of oleuropein are available for human consumption and clinical testing
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@GarciaPaulineJ @TheRuggieroLab @LeGrandLab1 Congrats Pauline 🤩 I was super happy to see you shine in live 👏 and celebrate the well deserved accomplishment 🍸 Bravo @LeGrandLab1 for enabling success
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After seeing new world record by @mondohoss600 at #Paris2024 and reading association of elite sports with #longevity by @marc_dema lab, time to train for pole vaulting !!!!
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RT @Kei__Sakamoto: A PhD position on metabolic signaling #AMPK is available in our Group @LabSakamoto at @Metabolcenter in Copenhagen. See…
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RT @davidjglassMD: Each year, the journal Skeletal Muscle's Impact Factor keeps going up. Now it's at 5.3 for 2-year impact, 5.0 for 5-yea…
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RT @ISMCopenhagen: @grith_hojfeldt giving a stellar presentation at #ibec2024 @UL on our recent collaboration with @FeigeLab and colleagues…
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@TheBurro34 @DHWasserman1 Terribly sad news to lose a reference for physiology ! All thoughts to family, friends and direct colleagues
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RT @AnaisFrancoRom1: Happy and proud to share our new paper about MYTHO in @jclinicalinvest 🎉 “ C16ORF70/Mytho promotes healthy ageing in…
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1/ we generate a new tool that can be shared in the community 2/ we confirm that Myf5 expression marks the depth of #quiescence and self renewal capacity via asymmetric division 3/ we demonstrate that #aging specifically affects MuSCs with deep quiescence (Pax7+/Myf5-)
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RT @RemiRmounier: Two days before the end of the early bird application for our EMBO workshop "Skeletal Muscle Development, Metabolism, and…
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