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M Velia Antonini Profile
M Velia Antonini

@FOAMecmo

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CCP E-AEC ECMO & NRP specialist + POCUS @EuroELSO Steering C & Chair NRP WG @ELSOeducation taskforce SoMe Director @ELSOOrg SoMe Editor @yourICM @asaiojournal

Italy
Joined February 2011
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@FOAMecmo
M Velia Antonini
1 year
Transesophageal #ultrasound guided normothermic regional perfusion in cDCD donors, how we do it: detailed description of technique we use for #EISOR (is also worth reading if you use #REBOA ), just out, open access, on @asaiojournal 🔓 🖥️ guidewires & EBOA
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@FOAMecmo
M Velia Antonini
4 years
How to ventilate #COVID19 pts? Dr Camporota @Luigi_ICM shared model to approach reflecting phase of disease during amazing @ESICM webinar! hints: L or H phenotype? (soon on @yourICM by @gattinon ) #SARSCoV2 pneumonia is NOT #ARDS ! #FOAMcc #SARSCoV2 #Coronavirus #COVIDFOAM
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@FOAMecmo
M Velia Antonini
2 years
Pathophysiology of fluid administration in #ICU ☔️ fluid challenge, bolus, infusion: does rate matter? 💧does type of fluid impact on outcome? ☔️ fluids response in acute circulatory failure: couple macro/micro hemodynamics #FOAMcc on @ICMexperimental 🗞️
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@FOAMecmo
M Velia Antonini
4 years
#COVID19 dedicated @GiViTI_IRFMN @MarioNegriIRCCS video conference with intensivists from North of Italy sharing their initial experience with #Coronavirus #SARSCoV19 epidemics: LUS, proning, MV #ECMO ... it's like a tsunami, you can't understand if not in #FOAMcc #FOAMed #FOAMus
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@FOAMecmo
M Velia Antonini
4 years
Managing critically ills #COVID19 pts? be prepared! be familiar with case definition, strict compliance with IPC @ESICM webinar by Prof @YaseenarabiYa with @Lennie333 Here my graphics, slideset & summary by @WhistlingDixie4 at #FOAMcc #FOAMed #Coronavirus
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@FOAMecmo
M Velia Antonini
4 years
MV is like recipe: same ingredients/different dosages may result in perfection vs disaster Low Vt does NOT guarantee lung protection: could be good starting point, but isn't THE solution, scale to lung size. Vt impacts survival (ARMA) only if really high/low @Luigi_ICM #LIVES2020
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@FOAMecmo
M Velia Antonini
4 years
Advices & informal algorithm by intensivists daily caring for pts w #SARSCoV2 in Milan, to stardardize approach optimizing outcome & resources consumption, & support HCPs dealing with severe #COVID19 resp failure by @Thom_Langer @Bottinik1 graphics @FOAMecmo #FOAMcc #COVIDFOAM
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@FOAMecmo
M Velia Antonini
2 years
How to assess systemic venous congestion with #POCUS ?? Evaluation of 🖥 IVC 🖥 hepatic veins 🖥 portal vein 🖥 renal vessels technique, interpretation & pitfalls, and #VeXUS score Open access #FOAMcc #FOAMus @EchoSoliman 📖
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@FOAMecmo
M Velia Antonini
2 years
🚑 Inside the mobile #ECMO truck of MN Mobile Resuscitation Consortium providing #ECPR in refractory #OHCA in Minneapolis, equipped to allow for echographic/fluoroscopy guided cannulation on the road @MMRCbeat @DYannopoulos #PraguECPR
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@FOAMecmo
M Velia Antonini
1 year
Prone position for acute hypoxemic respiratory failure & #ARDS , a review: ➡️ physiologic features: ventilation & perfusion ➡️ clinical outcomes ➡️ awake prone positioning ➡️ practical considerations ➡️ lingering questions & future directions @accpchest 🖇️
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@FOAMecmo
M Velia Antonini
4 years
Everything about fluids @Manu_Malbrain #IFAD2020 🔹7⃣Ds & fluid stewardship 🔹(fluids related) definitions 🔹4⃣questions 🔹4⃣indications 🔹4⃣phases & ROSE conceptual model 🔹fluids myths 🔹main references Graphic @FOAMecmo #FOAMcc Full talks available at
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@FOAMecmo
M Velia Antonini
4 years
Ever experienced membrane lung failure on #ECMO ?? 📌 mechanisms of ML (function &) dysfunction 📌 ML monitoring 📌 algorithmic approach to troubleshooting @Crit_Care #FOAMcc #FOAMecmo So proud being among authors *Hint: do NOT miss supplementary info!
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@FOAMecmo
M Velia Antonini
3 years
Vasopressors in shock ➡️norepi 1st choice in septic/vasodilatory shock after volume #resuscitation , may be followed by vasopressin/epi ➡️angiotensin II/dopamine limited indications ➡️may ⬇️contractility: inotropes may be added, dobuta>milrinone @yourICM
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@yourICM
Intensive Care Medicine
3 years
Vasopressors in critically ill pts with shock: ➡️summary of evidence & pivotal trials ➡️relevant pathophysiology of vasodilatory shock ➡️when & what vasopressor(s) to administer? agents & receptor/effect(s), dose, additional benefits ➡️monitoring ➡️weaning
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@FOAMecmo
M Velia Antonini
4 months
Serum lactate poorly specific for hypoperfusion, more often associated with impaired tissue O2 use. Levels affected by  ⬆️ increased anaerobic glycolysis & ⬆️ aerobic glycolysis production ⬇️ impaired mitochondrial function ⬇️ reduced hepatic clearance Potential harm may result
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@yourICM
Intensive Care Medicine
4 months
Guiding resuscitation on serial lactate measurements? Not an accurate biomarker of hypoperfusion. However integration with clinical phenotyping + peripheral perfusion assessment could better individualize strategies 🔓 Refers to 🔓
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@FOAMecmo
M Velia Antonini
2 months
Pulmonary shunt in critical care, practical approach w clinical scenarios 📚 background 🫀🫁definitions: shunt, ventilation/perfusion mismatch, dead space 🩸O2 blood content 🫁 pulmonary shunt 🛏️ shunt measurement in practice 🔮 future directions #FOAMcc 🔓
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@FOAMecmo
M Velia Antonini
1 year
Acute RV injury in surgical & critical care settings 🔗 🫁 acute respiratory distress syndrome #ARDS 🧫 #sepsis & septic shock 🟤 liver disease & #transplantation 🫀 management of RV Injury & Failure #ThePeoplesVentricle 🫀 2 just out on @JCVAonline Also
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@FOAMecmo
M Velia Antonini
3 years
What is going on here?? Multiple & coalescent round fomations appearing through venous side of this membrane lung during a VV #ECMO run in a patient with #COVID19 , couple of days after emergent cannula replacement. #FOAMcc #FOAMecmo #COVIDFOAM on @yourICM
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@FOAMecmo
M Velia Antonini
5 years
Basic #echocardiography infograph based on @ESICM #LIVES2019 masterclass! you are captain of the ship, manipulate probe on chest till you find good acoustic window but do not pretend to do full echo study, learn basis first #FOAMus #POCUS graphic @FOAMecmo scans @Wilkinsonjonny
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@FOAMecmo
M Velia Antonini
4 years
Hemodynamic management in #COVID19 notes based on A Messina talk @HumanitasMilano @ESICM webinar Start from clinical examination, add #POCUS to basic monitoring (ie PPV), complex tools in selected cases only #COVIDFOAM video slides
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@FOAMecmo
M Velia Antonini
1 year
🌡️Fever 1⃣ measure t° accurately 2⃣definitions vary 3⃣diagnostic workup? only in some pts 4⃣consider non‑infectious causes 5⃣treat MH 6⃣7⃣8⃣ sepsis? careful w control; NO fever? NO good sign; paracetamol/cooling doN'T ⬆️ outcomes 9⃣BI? 🔟 control post CA 🔗
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@FOAMecmo
M Velia Antonini
1 year
Acute RV injury in cardiothoracic surgery & #ICU , 1 🫀 cardiac surgery: CPB/myocardial protection, RV afterload, RV ischemia 🫀🫁 heart & lung #transplant 🫁 chronic thromboembolic PAH 🫀 #LVAD 🫁 thoracic surgery: one-lung MV/lung resection @JCVAonline 🔗
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@FOAMecmo
M Velia Antonini
5 years
Managing VA #ECMO 1 mind mixing cloud 2 retaining LV pulsatility critical! 3 prevent/recognize/manage #ECLS complications 4 weaning when & how 5 exit strategies infograph freely based on @KasiaHrynia talk at @ELSOOrg 2018 waiting for #ELSO2019 @ECMOed #FOAMcc #FOAMed #FOAMecmo
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@FOAMecmo
M Velia Antonini
4 years
Delayed fluid therapy can lead to ischemic injury, irreversible shock with multisystem organ system; here 10 papers we should know about #resuscitation fluids: #IFAD2020 Rodriguez G 1⃣CRISTAL RCT @JAMA_current 2⃣SAFE Study @yourICM
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@FOAMecmo
M Velia Antonini
9 months
Topical, nebulized, endobronchial, systemic tranexamic acid to manage surgical & medical bleedings on #ECMO 🩸TXA commonly used as adjunctive hemostatic agent 🩸systemic TXA use low, guided by local protocol involving multidisciplinary approach & rigorous VET monitoring
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@FOAMecmo
M Velia Antonini
3 years
Evaluating volemic status & fluid management @DrMCecconi #eSMART2021 tutorial 🧵 🩸vessels: elastic compartment, fluid filled (blood) 🩸Unstressed Volume: fluid not generating stress on vessels walls 🩸Stressed Volume: fluid generating stress = Pressure = mean systemic filling P
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@FOAMecmo
M Velia Antonini
1 year
🩸Intro to #ECMO for new #ICU staff 🎥nomenclature/circuit components 🎥VV: principles, indications, complications, weaning 🎥VA #ECLS : principles, indications, complications, weaning 🎥 #ECPR in cardiac arrest 4 open videos @intensiveblog #FOAMcc #FOAMed 🔗
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@FOAMecmo
M Velia Antonini
3 years
Why measuring respiratory drive & effort in #ARDS ?? ➡️high breathing effort? ➡️ lung stress/strain + diaphragm injury ➡️monitor effort at bedside (ie Pes, P0.1, EAdi) ➡️prioritize lung vs diaphragm protective MV @DrLeoHeunks #eSMART2021 📰 PS read @yourICM
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@FOAMecmo
M Velia Antonini
1 year
Unloading LV in VA #ECMO : 🎈 physiological basis 🔮 whom to unload? hemodynamic, #POCUS & clinical predictors ⚙️ how to unload? noninvasive and pharmacological approaches, venting & unloading strategies ⏰ when to unload? ➡️ unloading targets @CircAHA 🖇️
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@FOAMecmo
M Velia Antonini
1 year
Management of short-term #MCS for cardiogenic shock in adults in cardiac #ICU , consensus by ACVC of @escardio @ESICM @EuroELSO & @EACTS 🔓Open #FOAMcc at 🚦 indications 🫀 cannulation for VA #ECMO & implantation of axial flow pump 🖥️ monitoring 💉
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@FOAMecmo
M Velia Antonini
2 years
Why to assess preload responsiveness? 💧NOT all pts even in shock are fluid responsive 💧assess frequently: dynamic phenomenon 💧fluids in non-responders? risky 💧overload harmful: +ve balance ⬆️ mortality 💧use of fluid responsiveness tests ⬆️ outcome Teboul JL @ESICM webinar 🧵
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@FOAMecmo
M Velia Antonini
1 year
Lung ultrasound in acute & chronic heart failure 🖥️ findings: B-lines, pleural effusions & other #POCUS features of congestion & deaeration 🖥️ LUS technique 🖥️ clinical applications: diagnosis, monitoring, prognosis & follow-up 🖥️ integrated cardiopulmonary #ultrasound 🖥️ gaps in
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M Velia Antonini
8 months
Proning pts with severe #ARDS on #ECMO , PRONECMO RCT: 🫁 170 pts: prone positioning (at least 4 sessions of 16 h) vs supine positioning ⏱️ no difference in time to successful weaning/run duration 📈 no difference in #ICU LoS/mortality ⚠️ no serious adverse events during PP
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@FOAMecmo
M Velia Antonini
3 years
Mechanical Circulatory Support in #ICU , post-implant care & management 🫀 #Impella : insertion, management, removal 🫀 IABP 🫀 #ECMO : configurations/management 🫀 ECpella: physiological basis/management of dual #MCS 🫀 general management issues @SCCM #FOAMcc
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@FOAMecmo
M Velia Antonini
3 years
Understanding gas analysis #eSMART2021 tutorial 🧵Starting from oxygenation: 🩸O2 content Hb bonded + dissolved in plasma 🩸lung capillary? assume Sat 100%; calculate PAO2 alveolar PO2 with alveolar gas equation 🩸enough Hb? CaO2 may be preserved despite low PaO2/SaO2 @Luigi_ICM
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@FOAMecmo
M Velia Antonini
3 years
Essential of lung/diaphragm #POCUS tutorial 🧵 🦇 sign identify lung in ICS (ribs acoustic shadows) __ pleural line moves w ventilation: visceral/parietal pleura sliding 🅰️ lines horizontal reverberation artifacts similar to pleural line (repeats = distance) Mongodi S #eSMART2021
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@FOAMecmo
M Velia Antonini
2 years
Temporary Mechanical Circulatory Support in refractory cardiogenic shock ♥️ definition & medical management of CS ♥️ overview of devices used in CS ♥️ escalation of tMCS ♥️ management of tMCS in #ICU ♥️ de-escalating/weaning @AHAScience #FOAMcc #FOAMecmo 📎
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@FOAMecmo
M Velia Antonini
4 years
Heart-lung interactions in pneumonia @ESICM webinar: De Backer D moderated by @Echotrainer basic physiology #ARDS & #COVID19 acute cor pulmonale fluid status/responsiveness (& assessment) slides + high res graphics #Coronavirus #COVIDFOAM #FOAMcc #FOAMus
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@FOAMecmo
M Velia Antonini
1 year
🫁 Management of severe #ARDS and refractory hypoxemia, narrative review exploring physiology & evidence-based management with focus on mechanical ventilation, adjunctive therapies, VV #ECMO 🔓 🫁 MV: low tidal volume, ventilator asynchrony, PEEP & its
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@FOAMecmo
M Velia Antonini
4 years
Before giving fluids, consider: 🔹is CO too low? 🔹should I give fluids? 🔹obvious fluid losses? Fluid overload is harmful, negatively impacting on prognosis; moreover, effects of fluid infusions are not constant ➡️ assess responsiveness/unresponsiveness! @PrXaMonnet #IFAD2020
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@FOAMecmo
M Velia Antonini
6 months
Left ventricular hemodynamics on VA #ECMO ?? Physiology insights from catheterization & 3D echo 🫀 high flow VA #ECLS decompresses LV by significantly ⬇️ LV preload with minimal ⬆️ in afterload 🫀 this ⬇️ LVEDP, LVEDV, LV stroke work, LV PVA #FOAMcc 🔓
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M Velia Antonini
8 months
Oxygenation on VA #ECMO , review aimed to highlight physiology, summarize current data reporting association with outcomes & outline an approach to titrate O2 @CritCareMed 📎 🫁complex determinants of systemic oxygenation: key circuit & patient factors
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M Velia Antonini
2 years
Fluids in sepsis? 💧adaptative to retain H2O/Na+ & ⬆️ lactate 💧few pts have lost/loose fluids 💧most fluids in #ICU drugs/nutrition 💧first 30 ml/kg standard care, probably OK in most, then bolus if marked hypoperfusion, stop if no improvement/⬇️ oxygenation @AndersPerner @ESICM
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M Velia Antonini
4 years
Missed @ESICM #COVID19 webinar with Professor Bin Du from China? here notes on #Coronavirus pandemic, clinical features, organ failure, need for mechanical ventilation; check ESICM blog & @WhistlingDixie4 thread for more data! #FOAMcc #FOAMed @ecmocard @CCRG_Research @APELSOorg
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@FOAMecmo
M Velia Antonini
1 year
Veno-Pulmonary Arterial #ECMO in severe #ARDS , all you need to know in this editorial!! ⚙️ physiology 📖 evidence 🫀🫁 VPA #ECLS & #ARDS cardiorespiratory phenotypes 🔮future @asaiojournal @prorvnet #ThePeoplesVentricle 🔓Just out open access #FOAMcc at 📖
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M Velia Antonini
4 years
Still a place for old monitoring tools in the #ICU ?? 1/2 📌 what is the problem with CVP? CVP does not tell us about fluid responsiveness, but we may still use for something else... about preload/right heart, so we should measure it!! @PrXaMonnet #IFAD2020 @Fluid_Academy #FOAMcc
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@FOAMecmo
M Velia Antonini
3 years
Venous Excess UltraSound?? window on venous (congestion) pathophysiology, which might guide precise fluid management! Here conceptual review + case series focused on #VExUS grading system: pathological basis, pitfalls, limitations #FOAMus #echofirst #POCUS
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M Velia Antonini
1 year
🫀🫁Weaning from of V‑AV #ECMO ?? How to assess readiness for decannulation of both VV & VA components? Here, novel rapid approach using off-sweep + controlled backflow test, to allow for prompt/complete removal of #ECLS , which could be appropriate for highly selected patients
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@FOAMecmo
M Velia Antonini
5 years
About significance of EtCO2 & how it relates to PaCO2, notes based on @gattinon talk at @Smart_Meeting_M 2018... back to physiology here! Waiting for #SMARTmi2019 full talk open access at #FOAMcc #FOAMed follow the hashtag and see you next May in Milan!
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@FOAMecmo
M Velia Antonini
4 months
Head-to-toe bedside #ultrasound for adults on #ECMO 🔓 🫀🫁 prior to ECMO initiation: echocardiography, indications-contraindications + choice of configuration, pre-cannulation findings, LUS 🚨 #POCUS during #ECPR 🖥️ procedural guidance: vascular access
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M Velia Antonini
1 month
🫁 🫀 Right ventricular injury in the setting of hypoxemia, hypercapnia, elevated RV afterload may impact on mortality in #ARDS on VV #ECMO : protecting RV to improve survival?? Cardio/(pulmonary) vascular physiological considerations on @asaiojournal 🖇️
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M Velia Antonini
4 years
Perfusion pressure is not exactly MAP: look at both sides of circulation: venous (dark side) of circulation need some attention! how much congestion is affecting organs?? VExUS Venous Excess #ultrasound @ThinkingCC #COVID19POCUS #POCUS #echofirst #FOAMus
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M Velia Antonini
1 year
Ventilator settings in #ICU : prioritize permissive over aggressive ventilation! 1️⃣ use low Vt 2️⃣ do not use high PEEP by default 3️⃣ check delta P & MP 4️⃣ reduce RR 5️⃣ use O2 wisely 6️⃣ integrate Schlultz M Utrecht 🇳🇱🫀🫁 @ESICM #LIVESforum #FOAMcc
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@criticcaredoc
Jan De Waele MD
1 year
👇👇👇Great summary on how to set the #ventilator in critically ill patients - 6-step approach in #mechanicalventilation ✍️ Marcus Schultz #LIVESFORUMUTRECHT
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M Velia Antonini
3 years
Our @ELSOOrg guidelines for adult & pediatric #ECMO circuits: ⚙️cannulation sites & cannula selection ⚙️circuit composition ⚙️tubings ⚙️membrane lung ⚙️blood pump ⚙️priming ⚙️monitorings ⚙️coming off emergently Just out on @asaiojournal open!! #FOAMcc
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M Velia Antonini
3 years
HFNC in acute resp failure: what guidelines say?? recommendations on @yourICM ➡️hypoxemic failure STRONG ➡️peri-intubation NO ➡️post-extubation CONDITIONAL ➡️postop CONDITIONAL high risk/obese @Bram_Rochwerg #ESICMwebinar Also read
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M Velia Antonini
4 years
Diaphragm main respiratory muscle: dysfunction frequent/impactful in critically ills How to assess? diaphragm #ultrasound 1 diaphragm excursion 2 diaphragmatic thickening/thickening fraction #DUS in #COVID19 ? non critical/critical pts NIV/IMV Boero E #COVID19POCUS #POCUS #FOAMus
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M Velia Antonini
2 years
Difficult weaning from VA #ECMO ?? 🔠 ABCDE structured approach to optimize management identifying impacting factors A arrhythmias B blood pressures & loading conditions C contractility/coronaries D dysfunction of mechanical origin E extracardiac factors 🖇
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M Velia Antonini
5 months
RABECA #REBOA as bridge to #ECMO in cardiac arrest 🧠 to increase brain prefusion 🫀 to increase coronary prefusion 💉 to achieve higher adrenaline blood concentration with lower dosage 🩸to provide accurate BP monitoring during CPR (if arterial line available) 🩸to stimulate
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M Velia Antonini
4 years
Surviving Sepsis Campaign guidelines on #COVID19 critically ills management in one visual abstract IPC hemodynamics Non-Invasive/Invasive ventilation therapy check post on @ESICM blog for high resolution pics/full text link #coronavirus #SARSCoV2 #FOAMcc
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@Dr_Cit
Giuseppe Citerio
4 years
Great graphic summary of Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19) All in one by @FOAMecmo free read at
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M Velia Antonini
1 year
New global definition of acute respiratory distress syndrome #ARDS @ATSBlueEditor Intubation? not required 💨 HFNO ≥ 30 L/min or NIVICPAP ≥ 5 cm H2O PEEP 🫁 hypoxemia: Pa02/Fi02 ≤ 300 mmHg or SpO2/Fi02 ≤ 315 mmHg with SPO2 ≤ 97% ☢️ 🖥️ bilateral opacities confirmed by: CXR,
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@YukiKotani5
小谷 祐樹 | Yuki KOTANI
1 year
New ARDS definition🫁 What's new👇 1⃣HFNO ≥30 L/m 2⃣SpO2/FiO2 ≤315 & SpO2 ≤97 3⃣Ultrasound diagnosis of bilateral opacities 4⃣Consideration for resource-limited settings But it's hard to know the consensus process from one-page abstract🤔 🔗 #FOAMcc
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M Velia Antonini
9 months
How to manage differential gas #ECMO ?? 🫀 mechanism of dual circulation 🫁 impact of dual circulation on gas exchange in different regions of the body 🟥 lack of competitive flow, no dual circulation 🟦🟥 dual circulation with impaired native gas exchange 🟥🟦 dual circulation
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M Velia Antonini
2 years
#ECPR vs prolonged conventional ACLS only in refractory #OHCA ⬆️ survival ⬆️ favorable neuro-outcome secondary analysis of Prague OHCA trial 🇨🇿 ⚡️⏳⏱ Better survival if initial shockable rhythm, younger age, shorter #resuscitation @Crit_Care #FOAMcc 🖇️
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M Velia Antonini
3 years
What an honour! My drawings showing recirculation on VV #ECMO featured on cover page of new issue of @asaiojournal !! This graphic is among the illustrations included in @ELSOOrg guidelines for #ECLS circuit in adults & pediatric pts, free open access at 🖇️
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M Velia Antonini
3 years
VV #ECMO in adults updated @ELSOOrg guideline: ➡️indications/contraindications ➡️rationale/configuration(s) ➡️cannulation ➡️imaging ➡️management: MV (pic ⬇️), fluids, coagulation ➡️weaning ➡️what to remember/avoid Just out @asaiojournal #FOAMcc #FOAMecmo
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M Velia Antonini
1 year
How to unload left ventricle during VA #ECMO ?? 🖥️ echocardiographic imaging protocol #POCUS 🖥️ aortic valve, ventricular size & LAP 🖥️ LV unloading device selection Open access #FOAMcc #FOAMus #echofirst @ESC_Journals @escardio 🔓
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M Velia Antonini
1 year
ECPR for refractory #OHCA , lessons from 3 RCTs 🖇️ 🫀 ARREST demonstrated efficacy of #ECLS for #OHCA in highly controlled & dedicated environment 🇨🇿 Prague OHCA showed that in similar environment, outcomes of cCPR may exceed presumed estimations by advanced
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M Velia Antonini
11 months
Cannulation configuration & limb ischemia-related complications on peripheral VA #ECMO in adults, @ELSOOrg Registry analysis on @CritCareMed ➡️ bilateral cannulation should be preferred approach if femoral cannulation 🖇️ 📊 > 19K patients, about 12k
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@FOAMecmo
M Velia Antonini
6 months
EXODUS, EXpert consensus On Diaphragm #UltraSonography in critically ill 🔓 Evidence-based statements on: ⚙️ diaphragm anatomy & physiology 🫁 ventilator impact in diaphragm #POCUS 🖥️ transducer settings & technique 🎓 learning & expertise 🩺 applications
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M Velia Antonini
4 years
Extracorporeal life support #ECLS in #ARDS ( #ECMO & #ECCO2r ) narrative review summarizing ➡️ physiological concepts ➡️ rationale ➡️ current evidence ➡️ complications ➡️ limitations ➡️ ethical dilemmas ➡️ future key research questions ➡️ challenges @yourICM
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M Velia Antonini
2 years
#POCUS to assess volume status/manage fluids? Volume is NOT preload, fluid responsiveness does NOT mean give fluids: assess fluids tolerance! 🫀 right: IVC/RV size, portal/renal flows 🫀 left: MV inflow pattern, LA size, IAS, B lines @iceman_ex #LIVES2022
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M Velia Antonini
2 years
How to assess diaphragm with #ultrasound ?? ➡️ visualize diaphragm, hyperechoic line (left: use splenic window) ➡️ M-mode, 2/3 regular breaths ➡️ measure excursion; shallow breaths > 1 cm m/> 0.9 f ➡️ measuring shortening fraction feasible, not so easy B Cholley #LIVES2022 #POCUS
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M Velia Antonini
2 years
🦋 Brain #ultrasound ? NOT only in neurocritically ill but also in general #ICU ie after cardiac arrest or #sepsis 4 windows 🪟 temporal (major) 🪟 submandibular (carotid) 🪟 optical (linear probe for OSND) 🪟 suboccipital (vertebral/basilar) #LIVES2022 @chiara_robba @aartisarwal
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M Velia Antonini
6 years
Do you think you know anything about edema? to fully understand edema formation take a look at this infograph based on Pietro Caironi talk at #IFAD2018 meeting @Fluid_Academy #FOAMcc #FOAMed
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M Velia Antonini
2 years
VA #ECMO & LV unloading: what's the evidence?? Noninvasive approaches should be immediately considered for all pts + aggressive catheter/device-based modalities should be considered early after #ECLS initiation in a pt-tailored way. #FOAMcc #FOAMecmo 📎
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M Velia Antonini
6 years
Everything you need to know about (periop)fluid physiology, infograph based on Robert Hahn talk at #IFAD2018 meeting @Fluid_Academy #FOAMcc #FOAMed
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M Velia Antonini
5 years
7 principles of Lung Ultrasound in Critically Ill #LUCI () & #echo diagnosis of lung consolidation Lichtenstein D masterclass at @ESICM #LIVES2019 take home message? fractal sign: non translobar vs lung sign: translobar #FOAMus #FOAMed #POCUS #echofirst
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M Velia Antonini
1 year
🫁 Hemodynamic impact of proning? Let’s protect lung & its circulation to improve prognosis! RV to be evaluated in supine position before/after turning prone ARDS pts if overload? Could RV failure be itself be an indication for PP, whatever blood gases? 🖇️
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@yourICM
Intensive Care Medicine
1 year
🫁 Let’s protect lung & its circulation to improve prognosis! Besides limiting VILI/improving oxygenation, proning protects pulmonary circulation, unloads RV, improves hemodynamics, maybe partly explaining its beneficial effect especially if RV failure. 🖇️
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M Velia Antonini
4 years
Everything you need to know about fluid therapy: 📌fluids are not innocent 📌fluids are not just bag of water 📌fluids should be treated as drugs 📌fluids status matter: hypovolemia is bad, overload is worst!! Always consider 7 D's ➡️ fluids stewardship! @Manu_Malbrain #IFAD2020
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M Velia Antonini
4 years
AKI & #COVID19 : common in ICU patients (30–50% incidence); #AKI marker of disease severity & negative prognostic factor for survival. #RRT Renal replacement therapy is required in 10-20% of ICU pts with #SARSCoV2 infection Schneider A @ESICM #ESICMwebinar #ESICMtv #COVIDFOAM
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M Velia Antonini
3 years
#RESUS21 new @ERC_resus guidelines 🫀ACLS priority? high quality compressions/minimal stops early defibrillation, treating reversible causes 🫀consider rescue #ECPR (selected pts) if ALS fails or to facilitate procedures PS look at special circumstances CA
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M Velia Antonini
5 years
Efficacy of IV fluid administration & potential harm from fluids #resuscitation : complementary strategies may be used to prevent & treat overload: restrictive admin + active removal, look at ROSE model @Manu_Malbrain @Fluid_Academy open #FOAMcc #FOAMed
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M Velia Antonini
1 year
🩸 Anticoagulation in #ICU : search for safer anticoagulants continues! Bleeding & thrombosis main cause of morbidity & mortality on short-term percutaneous mechanical circulatory support as #ECMO , #IABP , #Impella , due to interplay of factors influencing haemostatic balance,
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@yourICM
Intensive Care Medicine
1 year
🩸Bleeding & thrombotic complications main cause of morbidity/mortality in critically ill pts receiving short-term percutaneous #MCS . The holy grail of anticoagulation in #ICU ? Prevent thrombosis without affecting hemostasis, increasing risk. #FOAMcc 🖇️
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M Velia Antonini
4 years
Using #ultrasound (& not only) to assess cardiac preload & fluid responsiveness @PrXaMonnet how to, advantages, drawbacks/limits & evidence of fluid/mini fluid challenge PVV/SVV ΔSVC/IVC recruitment EEO/EIO PLR full talk #FOAMcc #FOAMus #POCUS #echofirst
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M Velia Antonini
6 years
Understanding acid-base and beyond, Thomas Langer at post #IFAD2018 course @Fluid_Academy #FOAMcc #FOAMed
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M Velia Antonini
1 year
Do NOT miss on acute RV injury in surgical & critical care on @JCVAonline 1️⃣ 🫀🫁 cardiac & thoracic surgery 🫀🫁 heart & lung #transplantation 🫁 chronic thromboembolic PAH 🫀 #LVAD 2️⃣ 🫁 #ARDS 🧫 #sepsis & septic shock 🟤 liver
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@NephroP
NephroPOCUS
1 year
Sepsis induced right ventricular injury. #MedEd #FOAMcc #POCUS ARDS, acute respiratory distress syndrome; IL-1β, Interleukin 1 beta; IL-6, Interleukin 6; LV, left ventricle; NO, nitric oxide; ROS, reactive oxygen species; TNF-α, tumor necrosis factor alfa
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M Velia Antonini
4 years
In #COVID19 you may have severe hypoxemia with low recruitability; as consolidation increases with increased compliance/recruitability, treatment of same patient with same pathology & same degree of hypoxemia need to be adjusted (tailored) accordingly @Luigi_ICM @ESICM #LIVES2020
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M Velia Antonini
1 year
Gastrointestinal failure & injury in #ICU ?? We do not have proper definition of enteral feeding intolerance: consensus process needed, potentially leading to proper therapy. But how to define enteral function & GI dysfunction? Concomitant symptoms important! 🍽️ 1 symptom in pt
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M Velia Antonini
1 year
Weaning from VV #ECMO ➡️ V’O2ML ➡️ V’CO2ML ⬇️ effects of reducing EBF ⬇️ effects of reducing SGF without altering FdO2 ⬇️ effects of reducing FdO2 prior to reducing SGF ➡️ patient ➡️ ventilator ➡️ proposed (physiology based) approach @ICMexperimental 🖇️
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M Velia Antonini
7 years
Extracorporeal CardioPulmonary Resuscitation #ECPR response team: how physicians implements prehospital #ECMO on the streets of Paris #ECLS #ECPR @LionelLamhaut @alice_hutin photos @samudeparis
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M Velia Antonini
4 years
Theoretical distribution of intravenous fluids on infusion? consider 🔹1 lt "NS"/balanced crystalloids? ➡️ 820 ml go to interstitial/lymphatic space 🔹1 lt G5%? ➡️ 600ml go to IC space 🔹hypotonic NaCl/G4% ➡️ 480ml IC check @bmj_latest Nijsten M #IFAD2020
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M Velia Antonini
2 years
VA #ECMO , knowledge gaps 1️⃣ indications 2️⃣ selection criteria for #ECPR 3️⃣ cannulation: percutaneous vs open 4️⃣ therapy goals 5️⃣ BP & vasoactives, less is more? 6️⃣ transfusions 7️⃣ anticoagulation 8️⃣ endothelial activation/damage @ICMexperimental #FOAMcc 🗞️
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M Velia Antonini
10 months
How to write a meaningful paper (& get it published)? Prof M Slaughter @asaiojournal EiC #ELSO2023 The 3️⃣ Cs 🎯 Clarity of the message 🎯 Cohesion 🎯 Conciseness Common reasons for rejection ➡️ general: topic not of sufficient interest to readership, manuscript does not conform
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M Velia Antonini
1 year
10 tips to manage severe acute pancreatitis in #ICU #FOAMcc on @yourICM @JABERSamir3 🖇️ 1️⃣ Identify patients at ⬆️ risk 2️⃣ admit if organ failure 3️⃣ identify etiology 4️⃣ early abdominal CT to exclude differential diagnoses 5️⃣ monitor IAP (bladder P)
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@yourICM
Intensive Care Medicine
1 year
🏥 Prevalence of acute pancreatitis continuously ⬆️ over past decades. More than 10% of patients develop severe course requiring #ICU admission. Here 🔟 tips to give a quick guidance on how to manage critically ill patients with SAP. #FOAMcc on @yourICM 🖇️
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M Velia Antonini
3 years
#Extracorporeal CPR in cardiac arrest @DYannopoulos presenting Minnesota experience, recent launch of University of Minnesota's @UMNews mobile #ECMO program & ARREST trial. Main effect of time (CA to #extracorporeal reperfusion) on survival/outcome! @escardio @EuroELSO #ACVC2021
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M Velia Antonini
5 years
MV setting guided by waveforms mandatory skill in ICU; as asynchronies are frequent associated with inappropriate treatments/poor outcomes... do not wait them to occur!! Mojoli F at @Smart_Meeting_M 2018 waiting for #SMARTmi2019 full talk #FOAMcc #FOAMed
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M Velia Antonini
4 years
Mannitol vs HTS in intracranial HT? osmotic gradient ➡️ brain dehydration ⬇️ blood viscosity ➡️ cerebral vasoconstriction ⬇️ ICP hypertonicity ➡️ CSF reabsorption ⬆️ ICP + edema use HTS monitor electrolytes/osmolarity @NeurocritCareJ @drdangayach #IFAD2020
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M Velia Antonini
3 years
#ECMO in #COVID19 , updated @ELSOOrg guidelines: 📌program 📌pt selection 📌cannulation & ongoing care 📌weaning/discontinuation #ECLS in #PedsICU @JenelleBadulak @stead_christine @GraemeMacLaren @kshekar01 among authors, proud to be one! open @asaiojournal
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M Velia Antonini
3 years
One of major advancements in ARDS? understanding #ARDS strictly related to concept of baby lung: MV injurious in ARDS due to ⬇️ lung size inflated by Vt Dynamic strain (impacting on VILI/outcome)? Vt/FRC Compliance most close FRC estimate (NO PBW) @DomGrieco @ESICM #ESICMwebinar
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M Velia Antonini
5 years
Drug PK on #ECMO : how predict & prevent/limit changes optimizing therapeutic targets & minimizing toxicities/failures infographic based on my talk at EuroELSO2019; bit self-referential, but enjoy waiting for #ELSO2019 & register #FOAMcc #FOAMed #FOAMecmo
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M Velia Antonini
3 months
⏱️ #ARDS ? First 24 h = “golden” period which should be time stamped: 1️⃣ 🔍 first 3h of non-invasive/invasive respiratory support: rule in ARDS diagnosis 2️⃣ ⚖️ first 12h: decide to continue NIV or institute IMV 3️⃣ 🫁 first 6h: implement low Vt strategies & optimization based on
@yourICM
Intensive Care Medicine
3 months
⏱️ #ARDS : critical role of timing & order in standardized management, so that interventions are time-sensitive/sequential to ensure consistent, evidence-based treatments, maintaining open questions & opportunity for timely/finer individualization. #FOAMcc 🔓
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M Velia Antonini
2 years
Changes in cerebral hemodynamics on VV #ECMO 🧠 rapid, significant PaCO2 & MAP ⬇️ requiring ⬆️ vasopressors & resulting in ⬇️CBFV 🧠 ⬆️ eICP (⬇️ jugular drainage post cannulation??) 🧠 eCPP significantly ⬇️ despite vasopressors ⬆️ #FOAMcc @yourICM 🖇️
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