Choi Lab
@EunheeChoi12
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Cell biologist, Studying the role of cell division regulators in insulin signaling
New York, NY
Joined October 2019
Happy to share our recent work with @Xinru71 #BakerLab @XiaochenBai #insulin - Computational design yielded super agonists, partial agonists, and antagonists of insulin receptor. - Designed agonists tune IR signaling by modulating conformational dynamics of activated IR.
Now online: We created de novo insulin receptor agonists using computational protein design! @EunheeChoi12 @XiaochenB @PreethamVi @UWproteindesign #BakerLab
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RT @NobelPrize: Some words of wisdom from this year's chemistry laureate David Baker, whose work has made it possible to design new protein…
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RT @Nature: Nature research paper: Adipose tissue retains an epigenetic memory of obesity after weight loss
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RT @NobelPrize: "Insulin is not a cure for diabetes; it is a treatment." - Frederick Banting in his 1923 Nobel Prize lecture Read his ful…
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RT @NobelPrize: In May 1921, Fredrick Banting met his research assistant Charles Best in John Macleod's lab to begin their experiments with…
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RT @Nature: Researchers have created the most detailed 3D cellular map yet of a mouse embryo, visualizing close to eight million cells http…
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RT @MolecularCell: Online Now: Structures and pH-dependent dimerization of the sevenless receptor tyrosine kinase h…
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Register now! 2025 IGF GRC registration 👉 *Participation is limited to 150!!
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RT @Nature: Scientists have engineered a modified insulin that reduces its activity at low glucose levels
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RT @arpaialab: New paper in collab w/ @tdanino lab out today in @Nature! @andrewredenti, @JongwonIm8158 and team engineer probiotic E. coli…
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- De novo agonists induce a distinct insulin receptor active conformation. - Designed agonists are more potent than insulin, reducing glucose levels longer and activating disease-causing insulin receptor mutants.
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RT @Xinru71: Now online: We created de novo insulin receptor agonists using computational protein design! @EunheeChoi12 @XiaochenB @Preetha…
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RT @NobelPrize: “I love all the proteins so I don’t want to pick favourites." New chemistry laureate, David Baker, spoke about the technol…
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