Drugs for Neglected Diseases initiative
@DNDi
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International non-profit developing safe, effective, and affordable treatments for the most neglected patients. #BestScienceforAll
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Pinned Tweet
Huge congratulations to our Africa Ambassador
@MoniqueWasunna
, who will have the honour of delivering the keynote speech at the
@ASTMH
#TropMed24
Annual Meeting in November!
Dr Wasunna has dedicated her career to fighting on behalf of neglected patients,
#UHC
and
#access2meds
Scientist, Clinician and Global Health Equity Champion: Monique Wasunna will kick off this year's Annual Meeting in New Orleans, November 13. She is
@DNDi
Africa Ambassador and previously was Chief Research Officer for
@KEMRI_Kenya
.
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0
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21
Too few outside of Asia have heard about the Malaysian success story in combatting
#COVID19
. Join
@DGHisham
next week for a
#webinar
about how a public health response to COVID-19 can work.
#publichealth
#COVID19crc
6
324
663
Today is the birthday 🎂 of Carlos Chagas - Brazilian 🇧🇷 biologist, physician, scientist & bacteriologist. Active in public health, he discovered the protozoan Trypanosoma cruzi (named after his friend Oswaldo Cruz) that causes
#Chagas
disease.
#ThisDayinHistory
@fiocruz_en
8
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531
Thank you so much
@DGHisham
for bringing your support and expertise to the COVID-19 Clinical Research Coalition. The research data and experience of scientists in Malaysia will benefit all. Together, we can beat
#COVID19
.
#COVID19crc
@KKMPutrajaya
1
111
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Great news: our film “A doctor’s dream” just won the grand prix at
@WHO
#HealthForAll
film festival! Watch the inspiring story of a Congolese doctor who helped develop the 1st all-oral drug for deadly
#sleepingsickness
. Thanks to him & all our partners! 📽️
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It’s official: EMA has approved fexinidazole to treat
#sleepingsickness
!
A doctor’s dream of a simple all-oral cure becomes reality.
Travel to the DRC to discover what
#makingmedicalhistory
means for doctors and patients:
5
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We are scientists, physicians & policymakers writing in
@TheLancet
, launching an international coalition 🌐 to accelerate research 🔬 on
#COVID19
in resource-poor settings. Join us!
#COVID19crc
7
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265
📣 Ravidasvir is now registered as a safe, effective & affordable
#hepatitisC
treatment in Malaysia!
3
89
158
Thank you Dr Fauci for your leadership in the
#COVID19
response in the US. We are so proud that
@sharonstone
presented you with a Visionary Award at our 2018 gala. You are a true visionary.
@NIAIDNews
Our response:
8
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Malaysia and the state of Kerala, India have pursed innovative strategies for
#COVID19
. Join us on 21 July to hear what these regions can teach the rest of the world!
Featuring
@DGHisham
@shailajateacher
@paimadhu
Register now➡️
#COVID19crc
5
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Dr Bernard Pécoul,
@DNDi
Executive Director, has received Thailand’s Prince Mahidol Award 2020 for his contribution to furthering research and
#access2meds
for neglected diseases around the world. Congratulations!
#beatNTDs
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39
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‘Fighting
#skinNTDs
requires partnerships in different areas: building capacity, creating educational resources, strengthening leadership at country level, and researching better tools to diagnose & treat them.’
@oriolmitja
wraps up the
@WHO
#NTDRoadmap2030
webinar.
#beatNTDs
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Affordable new
#hepatitisC
treatment is safe and effective with 97% cure rate for patients, including hard-to-treat cases. Interim results from our clinical trial in Malaysia and Thailand:
#ILC2018
#access2meds
#HCV
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The Democratic Republic of Congo is
#makingmedicalhistory
! Today the country has announced registration of the first oral treatment for
#sleepingsickness
fexinidazole! Thanks to
@Sanofi
@OlyIlunga
@MinSanteRDC
@gatesfoundation
& others for this milestone
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What if the most powerful
#AI
technology could help the most neglected patients? We are partnering with
@DeepMind
’s
#AlphaFold
project to fast-track our efforts to find safe & effective drugs for people with
#Chagas
and
#leishmaniasis
.
@demishassabis
1/2
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#COVID19
“I felt inspired that we have leaders like
@shailajateacher
&
@DGHisham
: leading from the front, putting up a solid fight, and demonstrating that it is possible to show solidarity.”
@paimadhu
shares lessons we can learn from Kerala and Malaysia.
1
37
122
We were so honored to have
@sharonstone
at our 15th anniversary gala last night.
@DailyMailCeleb
covers the event
#making
medical history
7
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'We cannot sit on our laurels when we have the tools and a cure in hand for
#hepatitisC
.'
@DGHisham
at webinar on how Malaysia is moving forward to tackle
#hepC
.
Tune in now ➡️
@FINDdx
@myAIDScouncil
@KKMPutrajaya
#WorldHepatitisDay
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📢 Good news for
#sleepingsickness
: acoziborole, a single-dose treatment that we’re developing with
@Sanofi
, was shown to be safe & effective with treatment success rates of up to 95%. This simpler treatment could be a revolution for doctors & communities!
5
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Just released! 📽️ Our 20-year anniversary film, Out of the Shadows, tells the story of DNDi researchers around the world developing treatments for neglected patients who have lived in the shadows for too long.
#InnovatingTogether
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#COVID19
interventions in resource-limited settings need to be affordable, available, and adapted to the health care systems and the populations they are serving.
#COVID19crc
@TheLancet
▶️
0
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Last night, monuments around the world lit up✨ for
#WorldNTDDay
- sending a powerful message that it's time to
#EndTheNeglect
of the 1.7 billion people affected by neglected tropical diseases.
1
31
108
We’re excited to see the conditional approval of ravidasvir in Malaysia! Congratulations to all our partners who have worked with us for years to improve access to treatments for people living with
#hepatitisC
.
Kenyataan Akhbar KPK 4 Jun 2021 – Kelulusan Pendaftaran Secara Bersyarat Ravidasvir 200mg Tablet Bagi Rawatan Hepatitis C
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It has been such an honour for our team to meet with inspiring
#PrincessofAsturiasAwards
laureates in Spain this week – including Meryl Streep, recipient of the 2023 Princess of Asturias Award for the Arts.
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#HepatitisC
kills more people than malaria.
The tools exist to eliminate this silent killer, but for most people in low & middle-income countries, treatment remains out of reach. That's why we’re working on an affordable cure ➡️
#NobelPrize2020
#HCV
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90 years ago today, Alexander Fleming returned from holiday to discover a Petri dish contaminated by a mould that was dissolving bacteria he’d been studying. Fleming had discovered
#penicillin
, the first antibiotic. Today, we need new antibiotics to
#StopSuperbugs
.
#GARDP
#AMR
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Thrilled to see
@DeepMind
release the
#AlphaFold
Protein Structure Database! Having already used their cutting-edge tech to accelerate our research for the world's most neglected patients, we’re inspired to see it made available for everyone to use!
#NTDs
#beatNTDs
Today with
@emblebi
, we're launching the
#AlphaFold
Protein Structure Database, which offers the most complete and accurate picture of the human proteome, doubling humanity’s accumulated knowledge of high-accuracy human protein structures - for free: 1/
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3K
7K
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@DGHisham
@KKMPutrajaya
@PharcoC
@pharmaniaga_bhd
@3rdworldnetwork
@WHOSEARO
@MSF
@ClinicalRsrchMY
@FINDdx
@ICR_NIH
The clinical trial in Malaysia & Thailand showed that ravidasvir + sofosbuvir is safe and effective with high cure rates, including for hard-to-treat cases and people with
#HCV
&
#HIV
.
Read science explainer of results published in
@LancetGastroHep
➡️
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We’re making medical history! Celebs and friends arrive for our dinner to
#makemedicalhistory
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Today is
#WorldNTDDay
and it’s time medical innovation reached the 1.7 billion people affected by neglected tropical diseases!
At DNDi we’re
#100percentCommitted
to develop safer, simpler, and more effective treatments to
#beatNTDs
.
#BestScienceforAll
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Today is
#WorldNTDDay
! Neglected tropical diseases affect 1.7 billion people 🌍, but treatments are all-too-often unsafe, unsuitable or non-existent. We must keep innovating!
See how we’re
#100percentCommitted
to the
#BestScienceforAll
:
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This week, key figures and celebrities joined hands to support DNDi's 15 years of
#makingmedicalhistory
.
@NYC_Patch
captures the energy of the night with
@sharonstone
and
@TheRealAlekWek
.
2
17
78
Today is
#WorldChagasDay
. Did you know that more than 6 million people are living with
#Chagas
disease but 70% of them don’t know it?
Now is the time to improve access to diagnosis, treatment, and care for people with Chagas!
👉
#beatNTDS
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COVID-19: What can Malaysia and Kerala, India teach the rest of the world?
2
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Pfizer must allow researchers to access its
#COVID19
drug Paxlovid – in particular to those who want to study the optimal use of this antiviral in low & middle-income countries.
Our public statement on behalf of 26 African & global research organizations.
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Today is
#WorldNTDDay
! Medical research should be for all – not just diseases that can turn a profit.
By
#InnovatingTogether
we can bring people affected by
#NTDs
out of the shadows and develop safer, simpler, more effective treatments.
#UniteActEliminate
1
44
89
Kids living with
#HIV
have been neglected for too long. With Quadrimune, the “4-in-1” treatment we’re developing with
@CIPLA_Global
, infants & young kids will finally have a treatment designed specifically for them.
Price will be $1 a day or less ⬇️
6
44
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In 2018, Dr Kande’s dream came true: the first oral treatment for
#sleepingsickness
. For millions of people suffering from the disease, this means a new hope for cure. In 2019, we will carry on working to turn other dreams into reality & bring renewed hope for neglected patients.
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📣Good news for people affected by
#sleepingsickness
(and their doctors)!
Fexinidazole, the first 💊all-oral treatment for sleeping sickness, has been added to the
@WHO
Essential Medicines Lists for adults and children to treat both stages of this deadly neglected disease.
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Good news! A sweet-tasting, child-friendly '4-in-1' antiretroviral treatment for infants and young children living with
#HIV
has been approved in 🇿🇦 South Africa. We developed this combination treatment together with
@CIPLA_global
@CIPLARSA
.
3
44
84
What is the role of research, innovation & partnerships in African efforts to address the
#COVID19
pandemic?
Join our webinar with
@JNkengasong
@MTamfum
@bornanyaoke
& Prof. Helen Rees moderated by
@annesoy
.
🗓️2 Nov. Register ➡️
#COVID19crc
#AfricaCOVID19
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Great news! For
#WorldNTDDay
,
@DeepMind
&
@emblebi
researchers are for the 1st time releasing the predicted 3D shapes of nearly 200,000 proteins that constitute over 25 organisms on
@WHO
priority list of
#NTDs
& antimicrobial resistant bacteria.
#AlphaFold
1
27
82
‘The Prince Mahidol Award will have a major importance for the continuation of DNDi’s activities in South-East Asia.’
Watch Dr Bernard Pécoul share his reaction to receiving Thailand’s Prince Mahidol Award 2020 in recognition of his service to
#publichealth
.
2
19
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It's
#WorldNTDDay
– but what is an NTD?🤔
#NTDs
are a diverse group of tropical conditions identified by
@WHO
which are largely ignored by the pharmaceutical industry, disproportionately affecting the world's most vulnerable people.
🧵We're developing treatments for 6 of them👇
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DNDi is 20 years old! 🎂
We're grateful to our founding partners
@fiocruz
,
@ICMRDELHI
,
@institutpasteur
,
@KEMRI_Kenya
,
@MSF
,
@KKMPutrajaya
&
@TDRnews
who came together to address the gap in medical research for people living with neglected diseases.
#InnovatingTogether
.
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16
80
Neglected tropical diseases are:
⏹️ Diseases that kill, disable & disfigure
▶️ Not rare: 1.5 billion people at risk!
⏩ Mostly affecting poor and vulnerable people
⏸️ Neglected in medical research, so treatments are often ineffective, highly toxic, or unaffordable
#WorldNTDDay
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We welcome
@DrLuisPizarro
as our new Executive Director!
Under the leadership of Dr Pizarro, we will seek to deliver another 13 new treatments by 2028 and continue to help build a more equitable system for innovation and access.
#BestScienceforAll
3
27
77
Today’s announcement from the US Trade Representative that it supports negotiations for the WTO waiver proposed by South Africa and India is a welcome change from the US government and a result of the tireless work of many countries and advocates around the world. Congrats!
1
28
76
#WorldChagasDay
Chagas disease affects mainly poor populations in Latin America, killing more people in the region than any other parasitic disease.
All affected have the right to access comprehensive and universal care. It’s time to give patients visibility!
#beatNTDs
0
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#Leishmaniasis
is a complex disease, which makes it difficult to treat.
@wellcometrust
has committed £10 million to collaborate with us on the development of new generation oral drugs to treat this neglected disease. Thank you!
0
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A new vaccine for
#dengue
was approved last week in Brazil. We welcome this announcement, but treatments are still needed for people affected by this neglected disease. Despite 390 million infections per year worldwide, there are no specific drug to treat dengue.
3
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We are pleased to have received a new
@gatesfoundation
grant supporting our development of innovative new drugs for people with
#sleepingsickness
& river blindness.
Thank you for your support of our mission & activities!
#InnovatingTogether
#WorldNTDDay
7
15
74
Congratulations
@PeterHotez
! 👏
Congratulations to the remarkable
@PeterHotez
on receiving the 2021 Robert Wood Johnson Foundation David E. Rogers Award! Thank you for your life-saving contributions to public health, esp. in vaccine development, neglected tropical diseases &
#COVID19
.
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Today we honour the life and work of Dr Mwele Ntuli Malecela,
@WHO
NTD Director and champion for the medical needs of the most vulnerable. We have lost a leader.
#WomenInScience
Read the message from our Executive Director Dr Bernard Pécoul:
1
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Join us this Friday 26 February 🗓️ to learn about the
#TRIPSwaiver
proposal for
#COVID19
tools and its critical implications for Africa.
With speakers from the Permanent Mission of South Africa,
@MSF_access
,
@AfricaCDC
&
@cehurduganda
.
Register ➡️
3
42
66
Tomorrow Dr
@MoniqueWasunna
, Director of DNDi Africa, will be speaking at
@WHO
webinar on the role of innovation in control and elimination of neglected tropical diseases.
#NTDRoadmap2030
#beatNTDs
Register now ➡️
0
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Alistair Mukondiwa
@ali_ngezi
🇿🇼 shares his vision for the next decade in
#globalhealth
.
We want to hear from you! What is your
#VisionForGlobalHealth
? 💬
#beatNTDs
1
24
69
Great news: Egypt registers ravidasvir - 3rd country to approve this affordable
#hepatitisC
drug! Congratulations to
@PharcoC
and everyone involved! 👏
Ravidasvir is registered in Egypt today , thanks for everyone invitation in this long journey
2
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After 15 years, we’ve proven that not-for-profit research and development can deliver effective and affordable new 💊treatments. But what lessons have we learnt in delivering public-interest R&D?
Read our new policy paper ➡️
#DNDi15Years
#WHS2019
1
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📢Great news for raising awareness of
#NTDs
! The first-ever
#WorldNTDDay
will take place on 30 January 2020.
Let’s keep up the momentum. Find out more👉
#RLMForum
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'So many people are getting sick - it's dengue cases, malaria and gastro problems and we can't help them all.'
#Dengue
cases are soaring after the floods in Pakistan.
Dengue is a rapidly spreading climate-sensitive disease. No specific treatment exists.
0
41
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What lessons can we learn from Malaysia and Kerala's
#COVID19
response according to
@paimadhu
: Leadership, early action, trust in experts and science, investment in public health, and solidarity.
@DGHisham
@shailajateacher
1
16
64
“No matter where the first vaccines originate, they must initially reach priority groups worldwide, particularly frontline healthcare workers and the most vulnerable.”
@JeremyFarrar
, Director
@WellcomeTrust
, calls for global cooperation to face
#COVID19
.
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A message to countries as they input into the
#pandemictreaty
this week: When you fund research & development, we believe you should put terms & conditions in place to ensure equitable
#access2meds
& affordability. 1/6
#INB
#PandemicAccord
1
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65
The HEAD-Start project aims to simplify testing for
#hepatitisC
and make it more affordable. Find out about our collaborative work with
@FINDdx
& the Malaysian Ministry of Health
@KKMPutrajaya
@DGHisham
to scale up ‘test-and-treat’.
🎥
0
19
64
Trial results of new affordable
#hepatitisC
treatment showing 97% cure rate now published in
@LancetGastroHep
!
Ravidasvir + sofosbuvir has the potential to provide an additional affordable, simple, and efficacious
#publichealth
tool to eliminate HCV.
➡️
4
34
63
Results of a DNDi-led study presented today show that a much shorter treatment for
#Chagas
disease could be just as effective and a lot safer.
@ISGlobalorg
#JornadaChagas2019
2
34
63
#WorldMosquitoDay
🦟 Did you know that
#dengue
is the most widely distributed & rapidly spreading mosquito-borne viral disease in the world?
Due to climate change, the mosquito species that transmit dengue are spreading to new countries & regions, but there is no treatment yet.
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We particularly thank Pharco Pharmaceuticals who partnered with
@pharmaniaga_bhd
for the registration and supply of ravidasvir in Malaysia and South-East Asia. This is the first drug for
#hepatitisC
to be developed through South-South collaboration.
2
41
61
#InnovatingTogether
for the elimination of
#sleepingsickness
: our team participated in good stakeholder discussions at WHO last week to review progress including rolling out new 🔬diagnostics, 💊 treatments & vector control.
➡️
#NTDRoadmap2030
2
17
64
Cutaneous
#leishmaniasis
is a disfiguring disease that leaves life-long scars, mostly on the face, and can bring severe social
#stigma
.
In the lead up to
#WorldNTDDay
, we call for innovative research 🔬 to develop better treatments to
#EndtheNeglect
!
➡️
0
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61
Do you have
#Chagas
disease? Over 6 million people are living with Chagas but 70% of them don’t know it.
On
#WorldChagasDay
, help us raise awareness of this neglected disease by asking
#whereisChagas
. ➡️
0
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61
#COVID19
infections among healthcare workers have increased 203% in Africa since late May, according to
@WHOAFRO
. Many don’t have enough PPE, others have to work even if sick.
@AfricaCDC
warns of upcoming “catastrophic shortage” of health workers.
1
22
62
'I waited and waited for almost 10 years.'
When Ng Song Ping was diagnosed with
#hepC
, he received a 1st treatment that had no positive effect on him. He was eventually cured with the combination treatment ravidasvir + sofosbuvir. Watch his story ⬇️
1
41
61
Good news for
#leishmaniasis
patients and treatment programmes:
@WHO
has prequalified miltefosine from a new generic source. 🙌 Expanding the sources of quality approved miltefosine is key for improving
#access2meds
for this neglected disease.
🔶
1
23
62
“Bringing the treatment to the community level is key to eliminate
#hepC
. Bringing the evidence that it is possible is key for changing the strategy.”
@JMP_DNDi
about our work with
@FINDdx
& Malaysian Ministry of Health to scale up HCV diagnosis & treatment.
#WorldHepatitisDay
1
19
58
'Neglected diseases affect one in five people on our planet. Yet, this unacceptable situation is not inevitable. Today, we can choose not to ignore these patients.'
@DrLuisPizarro
speaking at the
#PrincessofAsturiasAwards
ceremony tonight.
@fpa
#beatNTDs
#BestScienceforAll
0
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#Dengue
🦟 is yet to have an effective treatment, despite impacting millions.
As dengue rapidly spreads due to
#climatechange
,
@dinuguruge
joins
@BFMradio
podcast to discuss whether this will finally be a wake up call to better address the disease:
🎙️
2
34
63
Why are some diseases neglected?
They affect people who cannot afford the prices 💰 that a profit-driven model of pharmaceutical development demands.
DNDi was created to address this gap: we develop treatments for people, not profits.
#InnovatingTogether
#beatNTDs
2
28
59
'Now we can tell the patients: I have a treatment for you right now.’
Hear from the doctors, patients, and public health leaders who helped develop a new safe, effective & affordable
#hepatitisC
treatment, which is now registered in Malaysia.
@DGHisham
1
36
60
New
#HopeForLeishmaniasis
!
@WHO
released new guidelines today for people with both visceral
#leishmaniasis
and
#HIV
recommending a combination treatment that showed high efficacy rates in studies we conducted with
@MSF
and partners in Ethiopia & India.
1
39
60
📣
@EMA_News
has adopted a positive opinion of fexinidazole for the treatment of T.b. rhodesiense
#sleepingsickness
.
This is the result of years of
#InnovatingTogether
with
@Sanofi
& the HAT-r-ACC consortium to find a better & safer cure 💊 for patients!
2
26
58
Current
#leishmaniasis
treatments are long, painful, expensive, toxic, and complicated to administer to people, especially in remote areas. There is a need to develop innovative oral drugs for people with this neglected disease.
#beatNTDs
1
38
59
.
@WHO
will be launching its 2021-2030 Roadmap for Neglected Tropical Diseases on 🗓️ 28 January.
Register now for the virtual event ➡️
Together we can
#EndtheNeglect
!
#NTDRoadmap2030
#beatNTDs
0
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58
Meet
@daisyhernandez
and
@PipStewart
, authors of ‘The Kissing Bug’ and ‘Life Lessons from the Amazon’, to discuss the inherent injustice in the treatment of
#Chagas
& cutaneous
#leishmaniasis
at a webinar moderated by
@DoctorYasmin
.
🗓️ 17 Feb | Register➡️
2
27
59
Congrats to Dr Bernard Pécoul, founder of DNDi, for receiving the
@ASTMH
Clara Southmayd Ludlow Medal at
#TropMed22
tonight in Seattle! The medal rewards 40 years of leadership in tropical medicine. For Dr Pécoul it is “ultimately about the patients.”
#IamTropMed
1
23
59
Research institutes in LMICs have what they need to quickly launch high-quality clinical research & swiftly identify workable solutions for
#COVID19
prevention, diagnosis, and case management.
@nathalieNTDs
answers
@SJC_Sutton
questions for
@medicine_maker
3
14
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