Margaret Brimble Profile
Margaret Brimble

@BrimbleM

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Medicinal chemistry molecule maker! Mother of Trofinetide/NNZ2566 FDA approved drug for Rett Syndrome tradename Daybue - Neuren/Acadia Pharmaceuticals

University of Auckland
Joined October 2014
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@BrimbleM
Margaret Brimble
26 days
RT @melindacapecod: Daybue Begins the Journey to Europe!
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@BrimbleM
Margaret Brimble
2 months
RT @andrei_yudin: Thank you ⁦@kurtilaszlo⁩ for organizing another excellent WIPOS (Winter In-Person Organic Symposium) in Honolulu! https:/…
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@BrimbleM
Margaret Brimble
3 months
RT @LOrealAustralia: Introducing the 2024 L’Oréal-UNESCO For Women In Science fellows: Dr Leah Smith of @otago, Dr Brittany Mitchell of @QI
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@BrimbleM
Margaret Brimble
3 months
RT @TotalSynthesis: #TotalSynthesis of (–)-Cordycicadin D and 3,4-trans-Cordycicadins A and B: Entry to the 3,4-trans-Fused Cordycicadin Fr…
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@BrimbleM
Margaret Brimble
3 months
Thanks for helping out with this Phil! Got there in the end.
@Phillip_S_Grant
Phillip Grant
3 months
Thanks for highlighting our work!
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@BrimbleM
Margaret Brimble
3 months
RT @DirkTrauner: Indeed, Total Synthesis papers are amongst the most downloaded, which is a measure of importance and broad interest. It is…
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@BrimbleM
Margaret Brimble
3 months
Good luck Marzieh! You did an outstanding PhD @ScienceUoA
@Marzieh_Ahangar
MarziehAhangarpour
3 months
I have moved to beautiful #Vancouver to join the @BrittonLab at @SFU ! I’m excited for my new postdoctoral journey and the adventures ahead. Thank you to everyone at @SCSatUoA for all the experiences and knowledge I gained in #NewZealand during my PhD and postdoc years.
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@BrimbleM
Margaret Brimble
4 months
RT @Rettsyndrome: Yet we have HOPE. Researchers have proved that Rett can be reversed in mice, delivered the first-ever FDA-approved treatm…
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@BrimbleM
Margaret Brimble
4 months
RT @melindacapecod: Rett Syndrome Awareness Month #3(a) @AcadiaPharma #RettSyndromeAwarenessMonth
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@BrimbleM
Margaret Brimble
4 months
RT @RettDad: Health Canada approves Acadia’s DAYBUE for Rett syndrome
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@BrimbleM
Margaret Brimble
4 months
Thanks also to @Phillip_S_Grant - another nice contribution from him before he launched his independent career in Singapore
@BrimbleM
Margaret Brimble
4 months
Nice work from talented PhD student Grace Drummond @ScienceUoA @MWC_CoRE thanks also to @AlishaGeurts for the finishing touches!
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@BrimbleM
Margaret Brimble
4 months
Nice work from talented PhD student Grace Drummond @ScienceUoA @MWC_CoRE thanks also to @AlishaGeurts for the finishing touches!
@OrgBiomolChem
OBC
4 months
Be sure to read research by @BrimbleM & co @Brimble_Lab @AucklandUni in our latest issue on the biomimetic synthesis of the bicyclic butenolide core of pallamolide A Find it in full here🔽
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@BrimbleM
Margaret Brimble
4 months
RT @sharecafetweets: Jon Pilcher - Managing Director & CEO - Neuren Pharmaceuticals Limited (ASX:NEU) is developing new therapies for highl…
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@BrimbleM
Margaret Brimble
4 months
RT @JOC_OL: In #OrgLett: N-Substituted Iminothiolane (NIT): A Promising Strategy for Protecting Lysine Side Chains for Solid-Phase Peptide…
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@BrimbleM
Margaret Brimble
4 months
RT @Kavianinia_Lab: Want to avoid problematic Dde migration during Fmoc-SPPS? Check out CJ Aguilar’s work introducing a new lysine side cha…
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@BrimbleM
Margaret Brimble
4 months
RT @Rettsyndrome: There are more than 10,000 known rare diseases & more than 95% have no treatment. But as of last year, #Rettsyndrome is N…
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@BrimbleM
Margaret Brimble
4 months
So excited to hear the results of the clinical trials for trofinetide/NNZ2566 at 9th World Rett Congress ⁦@Rettsyndrome@Rett- such a humbling experience seeing a molecule born in our lab ⁦@AucklandUni⁩ ⁦@ScienceUoA⁩ used in the clinic and now FDA approved!
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@BrimbleM
Margaret Brimble
4 months
RT @Rettsyndrome: October is Rett Syndrome Awareness Month.💜 Rett syndrome is a rare and devastating neurodevelopmental disorder that impa…
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@BrimbleM
Margaret Brimble
4 months
Emotional day opening the 9th World Rett Congress on the Gold Coast with Jacinta Rome and Claude Buda #Trofinetide #Daybue@AcadiaPharma⁩ ⁦@melindacapecod⁩ ⁦@Rettsyndrome@RettAssociationAustralia
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@BrimbleM
Margaret Brimble
4 months
RT @AcadiaPharma: We’re heading to Australia next week to share our latest findings in #RettSyndrome at the 9th World Rett Syndrome Congres…
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