Beatriz Gros
@Bealoquebea
Followers
5,416
Following
857
Media
850
Statuses
9,864
Gastroenterologist #IBD specialist at @hureinasofia @IMIBIC Help others grow their abilities and celebrate life. IBD education at
Edinburgh, Scotland
Joined August 2011
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Pinned Tweet
🌟Ever found yourself doubting about IBD new drugs doses? or forgetting Thiopurine metabolism details?
I've been there too
So I thought it could help having "IBD Cheat Sheets" and that is what I did:
I hope it helps as much as it helps me
1/2
#IBD
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Many of you know I love timelines & I have been updating the one on IBD trials/studies for some time🧵
The landscape is changing fast & there isnt enough space here to share all the content
As such I have created a website to collect it all and to make it interactive
50
160
448
Has it ever been difficult for you to find the latest guidelines or consensus on IBD from different societies?
Not anymore
⭐️New section “guidelines” in
And tomorrow newsletter with a new evidence corner and new trials added 🤩
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After my previous summary of IBD studies,I finished yesterday this timeline which is more visual. I hope it can be useful to see where we come from and where we go.
There may be some mistakes,but please I did it with my best intention, same with missing studies.
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IBD classifications,scores and indices are something we often use and I thought having the most used ones all together could be helpful
⭐️New section
Suggestions are welcome 🙏🏻
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Someone reached out suggesting I compile a summary of
#IBD
H2H trials
His suggestion motivated me to complete the one I had
🌟So, here it is over 35 trials. Hope it proves helpful!
You'll have to access the website to view it in full.
Happy to add
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My website made it to the US 🤩
This is like a dream although I have to admit my biggest followers come from 🇺🇸 with >45K visits within 15 months
@DDWMeeting
#DDW2024
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I don’t share much of my personal life on twitter but this day was absolutely worth it.
@fjseruf
and I finally married. Living in 2 different countries for 18 months has not stopped us!!
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7
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⭐️Exciting news! Our ulcerative colitis review published in
@JAMANetwork
@JAMA_current
A massive shoutout to the brilliant
@gilkaplan
and fantastic support from
@lasser_karen
This project has been a work of passion& meaningful networking
#UC
1/2
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The IBD landscape is getting intense with so many exciting trials! 📈
#IBD
cheatsheets just updated in light of recent publications 😃
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🌟 November-Exciting News IBD-EII! 🌟
🧵
🆕 Introducing the new "IBD multifactorial" section at
Delve into the risk & protective factors that have been associated with IBD onset.
Over 190 studies organized per year and type of factor!
11
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206
JAK-STAT pathways can be complex to understand, gaining insight into their functions helps us comprehend the consequences of their blockade.
Bearing this in mind, I have done a summary attempting to synthesize this complexity focusing on
#IBD
therapies, I hope it proves useful.
11
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I have been working on this project for months.
A website constantly being updated with summaries of all the important studies in IBD.
At the moment over 140 studies.
13
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1/ I've read the TACOS trial on the use of tofacitinib in acute severe
#UC
I'll break down some important highlights &/or reflections which I found of interest
(In any case, I recommend reading the full study)
🔎Important tweets are number 7 & 8
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Mom would have turned 65 today. She passed 9 years ago
Devoted to work and science
Fierce love for family and life
Always radiated joy
All these years taken from us. Life is short and fragile; we are remembered for the love we give. 🤍🤍
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When Attending to congresses I recommend keeping this in mind & being extremely polite and grateful to the person who has presented. The effort of preparing the talk plus the pressure of talking in front of others should be taken into account.
#UEGWeek
#UEGWeek22
@my_ueg
6
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Multiple successive switches from IFX originator to biosimilars are effective and safe in patients with IBD, irrespective of the number of IFX switches. 🧵
Our paper is open for you to read.
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Celebrating one year since I launched
In a year I collected >950 studies with >220k visits & >20k downloads
Huge thanks to everyone who supported along the way!
🙌 “In a gentle way, you can always shake the world”
Many of you know I love timelines & I have been updating the one on IBD trials/studies for some time🧵
The landscape is changing fast & there isnt enough space here to share all the content
As such I have created a website to collect it all and to make it interactive
50
160
448
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20
159
As many are sharing their top 2023 articles, remember on you'll find the most important RCTs & many other 2023 relevant studies
This has been an exciting adventure that I never thought would go this far in less than a year
Thanks for all the support
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I summarize many concepts for my residents and myself.
I did one of important studies in IBD ordered by year.Some suggested that I share it,as it may be useful to other people.
There may be some mistakes but,did it with my best intention.I know some info is left but cannot extend
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I grew up surrounded by science; my mum was a researcher throughout her life & dedicated herself entirely to it
In her memory & in honor of all women striving to carve out a place in a world that isn't always fair & equal for them
📷:mum giving me my MD title
#WomenInScience
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6
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Ileocaecal resection in newly diagnosed CD associated to improved long-term outcomes compared to TNFinh very nice presentation
@ManasiAgrawalMD
#IBD
#ecco2023
More data supporting the LIR!C trial
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At this
#ECCO2024
, I'm presenting my first poster from
⭐️This project became a reality thanks to everyone who supported it
Despite navigating the challenges w limited experience on websites,my passion propels this endeavor &I'm eager to share it with you
12
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Ever wondered how TNF inh work in
#IBD
?
Curious about the emerging TL1A inhibitors on the horizon?
🌟I've tackled these questions & created a comprehensive summary
Full-quality image at
More content coming this weekend!
Subscribe for free to stay
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Is there anything that I may have missed from the pre biologic/small molecule/immunesupressant screening?
It has been something that some of you asked me to add to
Please feel free to improve this summary, I really appreciate your help
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I’m still processing that I will be presenting at
#DDWMeeting
@AmerGastroAssn
Big thanks to
@charlie_lees
&
@LauranneDerikx
for your amazing support&mentoring over this almost 2 wouldnt have been possible without you.Also to rest of authors🙏🏻
#hereforDDW
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2
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Still, I am at a loss for words to describe how difficult It feels to leave
Thanks to everyone at WGH, you are really incredible
Charlie, thanks for trusting in my abilities & reminding me of all that I am capable of doing I will always be indebted.Our friendship means a lot 🙏🏻
After 2.5 years, today is Bea's last official day working in the Edinburgh IBD Unit.
It is difficult to express here what an incredible impact she has made on the entire team in Edinburgh.
Her hard work, dedication, passion and joy for the every day has impacted us all and
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Coconut water in mild-mod UC vs placebo (both arms+standard therapy)
🌟 response 57.1% vs 28.3%, p=0.014
🌟 remission 53.1% vs 28.3%, p=0.02
FC & 🦠 changes but not endoscopy w8
@ShomronH
&
@RichardPollok
will enjoy this reading, 🤔 outside 📦
.
6
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Thank you very much
@Iagorlago
and
@Iris_Dotan
for this prize. I feel so grateful, this would have never been possible without
@charlie_lees
@LauranneDerikx
@PlevrisN
@IBDNathan
@Gastro_GRJ
22
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🎉 Exciting news!
My website has hit an incredible milestone over- 100,000 visits in just 6 months!
✨It's a testament to the power of passion and determination. 💪
#ChaseYourDreams
#PassionProjects
#IBD
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🇪🇸🇬🇧Voy a escribir una línea de tuits para explicar por si le sirve a alguien cómo proceder para trabajar de médico en UK contando con los cambios del Brexit.
Lo cuento según lo que he tenido que hacer,puede que haya más opciones. Si alguien necesita ayuda no dude en contactarme.
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🌟When you dream big, the sky's the limit!
This month marks 18 months since was created, since then:
- I have summarized >415 clinical trial & much more
- Received >300K+ visits (from 152 countries)
- 1290 subscriptions
- 34,700 content downloads
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9
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The impact of the adherence to Mediterranean diet and physical activity on
#IBD
prognosis
⭐️Healthy lifestyle was associated with:
- Lower risk of mod-severe relapses (aHR, 0.250; 0.093-0.670)
- Steroids use (aHR 0.292; 0.103-0.828)
- Lower risk of mod-severe relapses (aHR
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107
My younger sister Monica Gros defended her thesis today, the result of great effort and passion
☀️She works as a mountain rescue doctor, and yet she managed to complete her doctoral thesis in her spare time for free (like almost all doctors in Spain) on IBS and the intestinal
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3
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The rational of advanced combination therapy in
#IBD
@bruce_sands1
presenting a great overview of the past and future of these combinations at
#ECCO2024
#ECCO24
1
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Ileocaecal surgery for new CD is associated with improved long-term outcomes compared to AntiTNF nicely presented by
@ManasiAgrawalMD
at
#DDW2023
#AGALIVE
#IBD
4
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People often ask me how I manage to tweet so quickly during congresses
Here's the trick!!!: I prep every session beforehand.
🌟 I compile a Word doc with titles, dates/rooms, and abstracts, which I print and take along for note-taking.
Why?
1⃣ Gain insight before the talk
2⃣
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🔬 Our latest real-world cohort study unveils exciting insights into Filgotinib's impact on ulcerative colitis treatment.
First real-world evidence published.
#UlcerativeColitis
#Filgotinib
#UC
1/4
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Perianal and intra abdominal fistulizing
#CD
management
✅team with the surgeons
❌antibiotics alone
✅antiTNF
❓other drugs
Great overview by
@MRegueiroMD
at
@DDWMeeting
#DDW2024
1
29
92
3rd update of the timeline of IBD trials & studies.
Thanks to all of you writing to remind me the missing ones. Team work 🤩
More than 120 studies. Doing this has been so helpful to organize my knowledge,hope this can help others.
8
23
89
Do not miss our work about authorship gender representation of
#IBD
trials from 1955-2023
You will find it at
#ECCO2024
poster presentation number 791
⭐️this work has been possible thanks to
@JosephHabibi_MD
@BassiMehak
@DCharabaty
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This month in new additions!
⭐️ 12 new summaries in the timeline
⭐️ New cheat sheets
and much more!!
If you don't want to miss any of these you can
subscribe for free
If you don't enjoy it you can cancel anytime, we will miss you but this will allow
1
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85
Kono-S anastomosis associated to ⬇️ risk of postop recurrence in CD.
Disease extension >50cm associated to ⬆️ recurrence.
The SUPREME-CD trial presented by Gaetano Luglio at
#DDW2023
#AGALIVE2023
@DDWMeeting
@geteccu
2
31
87
“Bea why do you tweet everything at conferences?”
⭐️there are many reasons, like benefiting those who cannot attend BUT one is purely for my own benefit
Using twitter as a diary!! It helps me easily find & review data, prepare talks…
📹Here a video of an example
Hope it
3
4
87
Monitoring calprotectine in IBD using a sweat wearable device.
Amazing future to come
#DDW2023
#AgaLive2023
@geteccu
@DDWMeeting
6
20
86
TDM in
#IBD
, when it refers at least to antiTNF there should be little to no debate on this topic at this stage but for some reason still is 🧐
Great summary from Adam Cheifetz
At
@DDWMeeting
#DDW2024
4
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4
20
82
Such an outstanding talk by
@charlie_lees
as always. Fascinating to finally see the
@predicct
study data at
#DDW2023
#AGALIVE2023
@DDWMeeting
8
18
81
Speechless seeing the impact of the latest post on the website!
Over 23k visits in 4 days, now soaring past 180k in under 10 months.
Grateful for the trust in my work—this support only fuels my drive to keep pushing boundaries.
Thank you all!
🌟 November-Exciting News IBD-EII! 🌟
🧵
🆕 Introducing the new "IBD multifactorial" section at
Delve into the risk & protective factors that have been associated with IBD onset.
Over 190 studies organized per year and type of factor!
11
78
206
7
7
82
SEQUENCE in detail (RIS vs UST in
#CD
)
Summary: RIS non inferior to UST in clinical rem w24 & RIS superior UST in endoscopic rem w48
Some relevant details for me:
1⃣Open label- patients & clinicians knew drug assignment (central reader blinded) this differs from VIVID (MIRI vs
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82
Ileocaecal resection may have a role as first-line therapy in
#CD
, findings supporting the results from the LIR!C trial 🤩
Congratulations
@ManasiAgrawalMD
@JeanFredericCo1
@ryanungaro
@DrTineJess
and rest of authors
1
21
81
IBD Family plus loads of missing people
This is the biggest motivation to come to
#ECCO2023
@DCharabaty
@AshkanRA
@DrMohamadShehab
@AlfonsoElosua
@PaulaCRFSousa
@bverstockt
@ign76
@LauranneDerikx
@LumirKunovsky
@JosephHabibi_MD
#Petr
#Nuru
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9
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Happy to share my views on how social media has become an indispensable tool for disseminating health information at
@my_ueg
6
16
79
0
15
79
🤔Ever found yourself thinking, 'Should I prescribe this drug for my IBD patient that will also treat his/her other IMID?
Are you aware of which drugs are approved for which indications? It certainly confuses me🫣
Just until now,
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78
Muchísimas gracias a
@saludigestivo
y a la
@sepdigestiva
por este premio. Me siento muy afortunada. Y más compartiendo este rato con
@mjgarciadig
también premiada🤩
9
12
78
This
#ecco2023
has been great to learn, to share experiences, to see colleagues and friends again.
Cannot express enough how wonderful has been to meet again.
5
9
77
Subscribed to ? 📩
Get ready for a captivating month! Check the 'back to basics' in CD
From pioneering AZA and steroid trials to the first cA2 (infliximab) experience
Uncover these timeless, golden treasures. Don't miss out!
#IBD
⬇️👀new timeline slides
4
18
76
Some of our Edinburgh IBD unit posters 🤩🤩 fantastic work team!!!
@reb_hal
@Gwotzerho
@IBDNathan
@charlie_lees
@Gastro_GRJ
@ShahidaDin1
@AKA_Dr_E_Watson
@Edin_IBDScience
@PlevrisN
@LauranneDerikx
@mathewlyons
@claire_ohare_
2
11
72
Managing and understanding perianal fistulas in CD very nicely presented by
@HolubarStefan
at
#DDW2023
#AGALIVE2023
@DDWMeeting
0
27
72
Congratulations! Fantastic update 🤩
Relevant changes from 2019
✅do not stop biologicals prior surgery (2019 was conditional)
❌no fibrin glue for perianal
✅IFX & ADA for perianal
❓VEDO, UST, RIS, UPA in perianal
And much more relevant data!
Definitely 👍
Hot off the press : the
#ECCO
2024
#Guidelines
on Therapeutics in
#CD
: Medical Treatment. Excellently lead by Hannah Gordon and
@IBD_MB
, in close collaboration with ECCO GuiCom,
@efcca
and many clinicians globally.
@Y_ECCO_IBD
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6
24
72
VIVID-1 h2h trial with mirikizumab vs ustekinumab in
#CD
✅mirikizumab achieved non-inferiority to ustekinumab
❗️Be aware this is not like SEQUENCE! Patients here were around 50% previously exposed to AntiTNF whereas SEQUENCE all were previously exposed and the trial design
2
27
71
The importance of dietician help to manage patients with IBD not only during active disease but also to reduce functional associated symptoms when they are in remission presented by Lauren Manning
#UEGWeek
#UEGWeek22
@my_ueg
1
18
71
Monthly update on
⭐️New IBD cheatsheet focusing on anti-IL12/23- including the dual action of guselkumab observed in vitro*
⭐️ 8 new summaries on the timeline, new guides, and studies on multifactorial
#IBD
and much more!!
Don't miss out—subscribe for
0
25
70
Mistakes in surveillance in IBD presented by
@Rutter_Matt
very clear and useful presentation
#UEGWeek22
#UEGweek
@my_ueg
1
25
70
FC levels show varying correlations with inflammation depending on the specific bowel segment that is affected
Patients with
#CD
assessed by VCE
Very useful to have these cutoffs
✅ proximal SB FC>=77
✅distal SB FC >= 123
✅ colonic FC>=291
Congratulations, this is a very
FCP is better for colonic > small bowel (SB) inflammatiin, but how accurate is it in proximal vs. distal SB?
Using VCE as gold standard, our
@sheba_medical
brilliant fellow
@OffirU
reports in
@JCC_IBD
a dilutional gradient of calpro along the SB !
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2
19
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Mi hermana es médico de rescate en el helicóptero que cubre el Pirineo Aragonés
Es una de las personas mas increíbles que he conocido y valiente como nadie
Este domingo sale en RTVE en un programa en el que muestran lo que hacen ella y su equipo
🤍
6
5
68
We lack data on proctitis in clinical trials, and information regarding whether left-sided colitis and extensive colitis respond differently is scarce.
⭐️This study provides valuable insights regarding tofacitinib response depending on disease extension
3
13
66
🌟Exciting news!
This month, I've been dedicated to enhancing the "Evidence Corner" on , based on your feedback.
I've refreshed the "type of drug" section with the latest insights.
1/4
6
15
65
ECCO Topical Review on Biological Treatment Cycles in Crohn’s Disease
Congratulations
@PaulaCRFSousa
@fgomollon
@maria_chs
@jp_gisbert
@TrianaLobaton
@PFvRheenen
@MJCasanovaG
@peter_bossuyt
@BettenworthDb
@GabrieleDragoni
and rest of authors
2
21
65
Today is ostomy awareness day.
I am going to share some interesting data that some of you may know.
I hope this will help to raise awareness about this situation which is a life saver for many patients.
2
29
65
Our study at
@TAGastroenterol
Long-term outcomes & predictors of vedolizumab persistence in
#UC
✅ persistence exceeding 80% at 1y and 50% at 5y
🌟 previous exposure to biologics/small molecules, disease distribution & steroid at baseline influenced persistence
✅ no new
3
19
65
Outstanding lecture
@JoanaTo62523004
going through the evidence to support the superiority of TNFinh in CD
✅perianal disease
✅EIMS
✅long term safety data (including pregnancy)
✅also cheap
(Difficult to choose 4 slides as there were super)
@my_ueg
#UEGWeek
#uegweek22
#IBD
3
21
64
I am writing a post about Ramadan fasting and IBD.I am astonished there is only 1 study in pubmed published in 2008 which analyzed this.
The recommendations I found have sense but are expert opinions.
Now it is Ramadan&we have many muslims patients,appropriate info is needed.
5
8
61
Today starts Ramadan
Little reminder that we have little knowledge of the impact of this period on IBD course&recommendations are based on poor quality data
🤔taking into account it is 1 month/y & the amount of muslims in the🌍this is not admissible
5
12
62
Family planning, pregnancy and lactation
Great review at
#ECCO2024
#ECCO24
@JulsgaardMette
and Irit Avni Biron
1
18
62
I feel deeply honored to be in this list together with these amazing people
Thank you in advance if you vote for me to be awarded 🙏🏻🙏🏻
🤳First up: Our nominees for the
#HealioInnovators
Social Media Influencer are:
@DrBloodandGuts
@john_damianosMD
@Bealoquebea
@drpal_manickam
@GutsyGirlMD
@DrShambayati
You’re the judges! Vote here:
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6
13
62
Flying back home, therefore I stop my retransmission of the
#UEGWeek22
highlights.
It’s been a pleasure to see so many of you interacting with me and valuing my tweets.
See you at the ECCO 😊
6
2
62
LUCENT-1 and LUCENT-2 trials published!!
🌟mirikizumab (anti IL23)
🔎induction 300mg IV vs placebo clinical remission w8 (24.2 vs 13.3, p<0.001)
🔎maintenance 200mg SC clinical remission w40 (49.9% vs 25.1%, p<0.001)
3
18
61
We know Helicobacter Pylori is a group 1 carcinogen due to its link to gastric cancer.
But what about other solid malignancies?
What about other Helicobacter species?
Our latest publication in Cancers tries to shed a little bit of light in this regards
⬇️⬇️⬇️
5
13
62
Life is so much richer when you're surrounded by people who inspire you to be better, do more, and reach for your dreams. I'm so lucky to have found a group of friends who not only support me but also challenge me to grow
@DCharabaty
@JosephHabibi_MD
@LumirKunovsky
#DDW2024
1
2
61
Gaining perspective is not always easy but necessary
In
#IBD
a major source are Cochrane reviews
⭐️A new section is available as “IBD library” with all the IBDCochrane reviews for now (60 in total)
Some surprised me when I first read them🤩guess which
0
19
61
Today 9/4/23 it's just 2 months since the website was launched
I wanted to share some reflections and more importantly to 🙏thank you all🙏 for your appreciation and kind words plus the help that some of you gave me by reminding me missing studies 🧵
4
5
60
Inverse association between legume intake & colorectal cancer risk
Compared to no consumption:
- OR for at least 1 portion of legumes 0.79 (0.68-0.91)
-OR for 2 or > 0.68 (0.57-0.82) & estimate for an increment of 1 portion per week 0.87 (0.81-0.93)
2
18
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