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BARDA

@BARDA

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Advancing countermeasures against 21st century health threats by bringing together public private partnerships and advancing innovation. Part of HHS/ASPR.

Washington, DC
Joined April 2017
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@BARDA
BARDA
2 years
Today as BARDA enters our 16th year, we're releasing a new strategic plan focused on fortifying the nation’s #HealthSecurity by enabling a rapid response to #PublicHealth emergencies with #MedicalCountermeasures that save lives. Learn more:
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@BARDA
BARDA
4 months
Through the @RRPV_Consortium and #ProjectNextGen , we’re partnering with @castlevaxbio , Cyanvac, and @Vaxart to evaluate novel #COVID19 vaccine candidates that are needle-free. Learn more:
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@BARDA
BARDA
2 years
Two mask designs have been awarded $150,000 each as winners of the #MaskInnovationChallenge Phase 2 from BARDA, @NIOSH , & @NIST . Read the #BARDAStory about the designs from winners @Air99_LLC & @ReadiMask , as well as runners-up @Flo_Mask & @LeviStraussCo :
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@BARDA
BARDA
5 years
Today, we took steps to speed the development and secure domestic manufacturing of two vaccines – one by @Moderna_tx & another by @JanssenUS - to prevent the spread of #COVID19 and protect people at home and abroad.
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@BARDA
BARDA
7 months
Under #ProjectNextGen , we’re advancing the clinical development of next generation COVID-19 #vaccines that offer broader, longer lasting protection & that are easier to administer & reduce viral spread. This #NationalVaccinationDay , learn more:
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@BARDA
BARDA
1 year
The @T2Bio T2Biothreat Panel is the newest @US_FDA clearance of a BARDA-supported product. This molecular diagnostic test runs on the T2Dx instrument and detects & differentiates between 6 biothreat pathogens in a single sample. Learn more:
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@BARDA
BARDA
9 months
Under #ProjectNextGen , we are partnering with @Vaxart on planning a Phase 2b clinical trial that would compare its oral pill #COVID19 vaccine candidate to a currently approved COVID-19 vaccine. Learn more about Project NextGen:
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@BARDA
BARDA
1 year
Mucosal vaccines may have the potential to help prevent infection and transmission of COVID-19. Check out the latest #BARDAResearch to learn about progress in development & remaining challenges in getting vaccines to licensure:
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@BARDA
BARDA
1 year
BARDA is committed to supporting the next generation of innovative vaccine & therapeutic investments to help protect our nation against coronavirus and other infectious diseases.
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@BARDA
BARDA
4 years
We are joining forces with Tangen Biosciences to develop a fast, accurate, point-of-care molecular diagnostic test for use on the Tangen GeneSpark molecular diagnostic system to aid in diagnosing #COVID -19.
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@BARDA
BARDA
5 years
A Bluetooth-enabled, 60-second, point-of-care #COVID19 diagnostic test that could help clinicians to more quickly and effectively diagnose patients is being developed through a partnership between BARDA and @hememics .
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@BARDA
BARDA
1 year
We’re excited about Project NextGen which supports vaccine innovation efforts to enhance efficacy & accessibility of vaccines for future pathogens with pandemic potential – they will ideally be developed faster, easier to transport, & cost less compared to current vaccines.
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@BARDA
BARDA
2 years
Today, we purchased a supply of @Amgen ’s Nplate, a drug to combat the effects of acute radiation sickness after radiological or nuclear emergencies. For more about how we leverage existing technology & inventory management practices to ensure preparedness:
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@BARDA
BARDA
1 year
🆕 As a part of Project NextGen, we opened a new area of interest (AOI 15) under our Broad Agency Announcement (BAA), seeking submissions for the clinical development & efficacy of phase 2-ready next generation #COVID19 vaccines.
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@BARDA
BARDA
4 years
We’re partnering w/ @JPEOCBRND to provide subject matter expertise to @humanigen to support development of a monoclonal antibody therapeutic w/ potential to treat cytokine storm, reducing hospital stays & preventing lung damage from #COVID19 . Learn more:
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@BARDA
BARDA
5 years
We are expanding our partnership with @sanofi to accelerate the development and large-scale manufacturing of a recombinant #COVID19 vaccine that leverages the company’s existing recombinant vaccine platform.
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@BARDA
BARDA
5 years
We are proud to partner with @Regeneron to develop a potential therapeutic needed to #SaveLives from #COVID19 . BARDA is supporting the Phase 2/3 clinical trial for this product.
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@BARDA
BARDA
6 months
BARDA joined partner Jubilant HollisterStier for a ribbon-cutting ceremony at their high-speed, commercial fill-finish line facility in Spokane, Washington. This project aims to enable faster domestic production of vaccines during a public health emergency
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@BARDA
BARDA
3 years
#ICYMI we developed a #sepsis training module with @SepsisAlliance , @ASPRgov and @CDCgov to help healthcare & EMS professionals recognize and manage at-risk patients in disaster settings. Take the training and see how we’re #SolvingSepsisTogether
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@BARDA
BARDA
4 years
Congratulations to the entire @Pfizer team on the 1st COVID-19 vaccine in the US granted with @US_FDA emergency use authorization. This EUA allows the BioNTech vaccine purchased by the US government to be shipped across America to those who need it most to #SaveLives
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@BARDA
BARDA
4 years
BARDA is delighted to announce that Gary Disbrow, has accepted the role of permanent BARDA director. Dr. Disbrow has served in many roles since 2007. Please join us in congratulating him as we continue to pursue our mission of addressing 21st century #HealthSecurity threats.
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@BARDA
BARDA
14 days
. @Vaxart announced the initiation of the sentinel cohort of its Phase 2b clinical trial, which we support under #ProjectNextGen . The trial will determine the efficacy, safety, & immunogenicity of their oral vaccine candidate. For more on our #COVID19 work:
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@BARDA
BARDA
4 years
We’re partnering w/ @JPEOCBRND & @Pfizer under #WarpSpeed on large-scale production & delivery of a #COVID19 vaccine. With authorization from @US_FDA , the millions of doses made could become part of a vaccine campaign to #SaveLives .
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@BARDA
BARDA
3 years
We’re excited to announce a partnership with Global Health Investment Corporation. The joint endeavor, BARDA Ventures, will use venture capital practices to accelerate innovative technology development to #SaveLives & mitigate public health emergencies.
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@BARDA
BARDA
2 years
For #NationalVaccinationDay , we’re recognizing our #CBRN Vaccine Branch’s investments to address multiple public health threats, as well as the importance of flexible vaccination strategies to protect all populations. To learn more, visit:
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@BARDA
BARDA
2 months
We're working w/ partners to develop alternative methods of vaccine administration like pills & nasal sprays. These vaccines can stimulate localized immune responses at the site of infection, elicit more diverse antibody responses, & avoid needles: #NIAM
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@BARDA
BARDA
1 year
An important #ProjectNextGen focus is advancing next generation therapeutics to treat individuals with #COVID19 & enable protection against the virus. #NPM2023
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@BARDA
BARDA
4 years
BARDA is continuing to invest in next-generation products to protect Americans from #COVID19 . So far, we have invested more than $1.5 billion in 29 products to help our nation beat COVID-19.
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@BARDA
BARDA
1 year
A key goal of #ProjectNextGen is to invest in #COVID19 vaccine and therapeutic candidates that have favorable attributes that potentially increase access to prevention and treatment by better meeting the needs of America’s diverse population.
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@BARDA
BARDA
2 years
We’ve released a Request for Information (RFI) seeking information from current and potential biopharmaceutical partners regarding the advanced development landscape of next-generation #COVID19 #vaccines . Submit by April 25, 2023. Learn more:
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@BARDA
BARDA
5 years
Today, the seventh BARDA-supported #COVID19 diagnostic test was issued Emergency Use Authorization by @US_FDA . This easy-to-use test was developed by @QIAGEN to be added to the currently approved the QIAstat-Dx Respiratory Panel.
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@BARDA
BARDA
5 years
BARDA is supporting a portfolio of #COVID19 diagnostics to enable early detection & help #SaveLives . This week, @US_FDA approved a BARDA-supported rapid, hand-held, point-of-care diagnostic test for SARS-CoV-2 that was developed by @mesa_biotech .
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@BARDA
BARDA
2 years
📣 Our BID Day 2 Breakout Sessions will cover BARDA’s efforts in supporting the innovation & advancement of #medicalcountermeasure development & national preparedness. There will also be opportunities to meet w/ stakeholders about funding & possible partnerships.
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@BARDA
BARDA
1 year
⏳ As a part of Project NextGen, we’re still seeking submissions for the clinical development of next generation #COVID19 vaccines. The Broad Agency Announcement is open for submissions. Learn more:
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@BARDA
BARDA
5 years
We are proud to partner with @OraSure to develop a rapid point-of-care #COVID19 diagnostic for use in clinical & hospital labs or for self-test. The test could be run on both symptomatic and asymptomatic patients and provide results in just 20 minutes.
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@BARDA
BARDA
5 years
We are proud to partner with @JPEOCBRND & SAb Biotherapeutics, Inc. to develop a therapeutic treatment for #COVID19 . This therapeutic uses tech that has the potential to be safer, more effective, & longer lasting than current polyclonal antibody therapies.
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@BARDA
BARDA
1 year
Project NextGen will accelerate and streamline research and development of vaccines and therapeutics against #COVID19 . BARDA & @NIAIDNews are collaborating on this effort to spur innovation through public-private partnerships.
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@BARDA
BARDA
5 years
🆕 The BARDA Broad Agency Announcement now includes seven areas of interest related to #COVID19 medical countermeasures, including vaccines, therapeutics, diagnostics and more. Find out about new opportunities for partnership ➡️ #HealthSecurity
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@BARDA
BARDA
5 years
BARDA is supporting US government market research to identify medical countermeasures with the potential to help address the #2019nCoV outbreak. If your company is developing diagnostics, therapeutics, vaccines, or other products, submit your ideas here ➡️
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@BARDA
BARDA
1 year
@T2Bio @US_FDA With the T2Biothreat Panel, clinicians can identify multiple bacterial organisms in a single sample within 4 hours, enabling patient care decisions 1-3 days faster than the current standard. This approach allows earlier treatment and can improve patient health outcomes.
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@BARDA
BARDA
4 years
Welcome to Sandeep Patel, PhD ( @innovationwonk ), DRIVe’s new director – here to make a difference and help #SaveLives with innovative approaches across the spectrum of systemic challenges to ensure our nation’s health security.
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@BARDA
BARDA
5 years
When BARDA Director Rick Bright got a minor cut while gardening, he wasn’t expecting it to get infected with MRSA. Find out how that cut & a delayed diagnosis led to the misuse of antibiotics, threatened patient health, increased healthcare costs & more.
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@BARDA
BARDA
1 year
⏳ As a part of Project NextGen, we’re still seeking submissions for the clinical development of next generation #COVID19 vaccines. The Broad Agency Announcement is open for submissions. Learn more:
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@BARDA
BARDA
4 years
Save the date: BARDA Industry Day 2020 Tuesday Oct 27! Spend the day with us during our first fully digital conference and learn how we are Responding Together, Preparing for Tomorrow. #BARDA2020
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@BARDA
BARDA
1 year
Hear from Dr. Robert Johnson, Director of BARDA’s Medical Countermeasures Program, about the effort between BARDA & @NIAIDNews to support development of new vaccines & therapeutics to better address #COVID19 & family of viruses through #ProjectNextGen :
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@BARDA
BARDA
1 year
Through #ProjectNextGen , BARDA, in collaboration with National Institute of Allergy and Infectious Diseases (NIAID), will leverage public-private partnerships to develop new vaccines and therapeutics to enhance our preparedness for future #COVID19 strains & variants.
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@BARDA
BARDA
3 months
Recently published: BARDA is supporting Phase 2b clinical trials of next-generation #COVID19 vaccines with potential to improve efficacy & safety through #ProjectNextGen . Learn about the goals of these BARDA-supported clinical trials & access the article:
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@BARDA
BARDA
5 years
Antibiotic resistance is a huge concern of BARDA’s. And it's one we must work together and take an end-to-end approach to solve. No one group has the solution, just as no single antibiotic is a silver bullet. #HealthSecurity #AMR #WorldAMRCongress @CARB_X @CMSGov
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@BARDA
BARDA
5 years
Today, we are expanding our existing #PublicPrivatePartnership with @JanssenUS to expedite development of a novel #coronavirus vaccine using proven technology. #COVID19 #2019nCoV
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@BARDA
BARDA
1 year
Registration now open! We will host a virtual workshop: #ProjectNextGen : Enablers for Innovative COVID-19 Vaccine Manufacturing on July 20, 2023, at 1:00 p.m. ET. Learn more and register:
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@BARDA
BARDA
1 year
Under #ProjectNextGen , we’re partnering with multiple companies to support acceleration of Phase IIb clinical trial initiation for next generation #COVID19 booster vaccine candidates and support data collection and statistical analysis:
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@BARDA
BARDA
1 year
Are you developing a new #COVID19 vaccine or treatment? Request a TechWatch meeting to learn about Project NextGen, a new initiative to accelerate next generation COVID-19 medical countermeasures and to tell our subject matter experts about your product:
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@BARDA
BARDA
6 years
Today, @US_FDA approved the first antiviral drug to treat individuals symptomatic with smallpox disease. This drug is major milestone for biosecurity and the 38th FDA approval of a BARDA-supported product.
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@BARDA
BARDA
1 year
One of the program areas for Project NextGen is Strengthen: to advance next generation COVID-19 vaccine candidates, including broader, more durable protection, and better transmission blocking capabilities.
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@BARDA
BARDA
2 years
Masks have played a critical role in combatting COVID-19. The BARDA, @NIOSH & @NIST #MaskInnovationChallenge is accelerating the development of the next generation of masks to protect the public from a variety of airborne threats. Read more:
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@BARDA
BARDA
4 years
Today, the ninth @BARDA -supported SARS-CoV-2 diagnostic test received @US_FDA ’s Emergency Use Authorization, helping to further expand #COVID19 testing capacity. @Hologic ’s Aptima SARS-CoV-2 assay can provide initial results in just 3 hours.
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@BARDA
BARDA
2 years
BARDA will fund @CARB_X over the next 10 years, leveraging global partnerships to transform early-stage antibacterial R&D into innovative #MedicalCountermeasures that help combat the growing threat of #AntimicrobialResistance ( #AMR ). Read more ⤵️
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@BARDA
BARDA
4 years
#MakingCountermeasures Day 26: A @ChembioDx technician runs the DPP® #COVID19 Antigen Test, being developed for the Chembio DPP® Micro Reader II with actionable results in 15-20 minutes
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@BARDA
BARDA
4 years
Congratulations to our long-standing partner, @JanssenUS , on their #COVID19 vaccine EUA. Janssen was the first of seven #COVID19 vaccine programs supported by BARDA.
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@BARDA
BARDA
4 years
We are proud to partner with @MayoClinic in concert with @US_FDA guidance to fight #COVID19 . More than 48,500 patients have been transfused with convalescent plasma as part of this BARDA-supported program.
@SecAzar
Alex Azar
4 years
All Americans can help spread the word: If you’ve recovered from #COVID -19, you can help join the fight by donating #plasma
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@BARDA
BARDA
4 years
We’re partnering w/ @JPEOCBRND , @Sanofi , & @GSK under #WarpSpeed to develop & produce an investigational adjuvanted #COVID19 vaccine, including a demo of large-scale vaccine manufacturing w/ an adjuvant to enhance vaccine effectiveness.
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@BARDA
BARDA
5 years
@SecAzar @POTUS BARDA is honored to support @POTUS ’s initiative to help #SaveLives in an influenza #pandemic by working, through #PublicPrivatePartnerships , to modernize influenza vaccines that strengthen #HealthSecurity .
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@BARDA
BARDA
6 years
We’re excited to announce that #DRIVe is teaming up with an academic consortium, led by @EmoryMedicine , @emorybmi , to further develop #deeplearning software to provide early warning of #sepsis in patients. #DRIVeInnovation #SolvingSepsis #MachineLearning
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@BARDA
BARDA
1 year
We're seeking innovative proof-of-concept technologies enabling on-demand manufacturing of next generation #COVID19 vaccine candidates using mRNA, recombinant protein, virus-like particle or viral vector platforms at the point-of-service. Submit by 9/1/23:
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@BARDA
BARDA
1 year
⏳ As a part of Project NextGen, we’re still seeking submissions for the clinical development of next generation #COVID19 vaccines. The Broad Agency Announcement is open for submissions. Learn more:
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@BARDA
BARDA
2 months
To ensure communities are protected against infectious diseases, we’re partnering to advance vaccine delivery methods, enhance vaccine storage capability, support vaccine research & development for safe, effective, accessible vaccines. Learn more:
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@BARDA
BARDA
1 year
Interested in submitting to our open AOI 15 for the clinical development & efficacy of phase 2 trial ready next generation #COVID19 vaccines under Project NextGen? Attend our live Q&A session on May 17. Submit questions & register at:
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@BARDA
BARDA
1 year
This #NPM2023 and year-round, we’re working with @NIAIDNews on #ProjectNextGen to strengthen vaccine capabilities against current & future #COVID19 strains & variants.
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@BARDA
BARDA
5 years
We are proud to announce the latest addition to our growing portfolio of #COVID19 medical countermeasure development projects! BARDA will partner with @JanssenUS on the development of a new therapeutic product to treat patients with #COVID19 .
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@BARDA
BARDA
4 years
Today marks the start of World Antimicrobial Awareness Week 2020 #WAAW . Each year, more than 2.8 million Americans develop drug-resistant infections and more than 35,000 die from them. Learn what BARDA is doing to combat #AntibioticResistance
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@CDCgov
CDC
4 years
#AntibioticResistance is one of the most urgent global threats to the public’s health. Any time #antibiotics are used, they can cause side effects and contribute to the development of antibiotic resistance. #WAAW
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@BARDA
BARDA
4 years
🆕 Announcing #BARDAVentures ! We are seeking a nonprofit partner to operate & manage a venture-style partnership of breakthrough technologies focused on advancing #HealthSecurity . #DRIVeInnovation #VC #VentureCapital
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@BARDA
BARDA
2 years
BARDA and @Crossject_ are working together to advance #HealthSecurity & #preparedness against nerve agent attacks. Under Project BioShield, we are developing a more efficacious & needle-free autoinjector seizure treatment for both children & adults:
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@BARDA
BARDA
4 months
One goal of our 2022-2026 Strategic Plan is to maintain a mission-ready response posture. To support this, BARDA is increasing U.S. manufacturing capabilities to produce #medicalcountermeasures at the scale needed for future #publichealth emergencies:
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@BARDA
BARDA
5 years
We are partnering with @Luminex to develop an easy to administer molecular diagnostic test for #COVID19 . The test can be performed in community hospitals and other facilities with access to medium-complexity labs.
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@BARDA
BARDA
4 years
We are excited that long-standing partner @Regeneron has received @US_FDA approval of the first safe, effective treatment for #Ebola . Inmazeb® is an anti-viral antibody ‘cocktail’ for the treatment of infection caused by Zaire ebolavirus in adult and pediatric patients.
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@BARDA
BARDA
1 year
For this AOI, next generation vaccines include those with enhanced breadth of protection against variants, improved durability, and those with an enhanced ability to block infection/transmission including mucosal vaccines, relative to currently approved vaccines.
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@BARDA
BARDA
1 year
There's still time to respond! We’ve released a Request for Information (RFI) seeking information from current & potential biopharmaceutical partners regarding the advanced development landscape of next-generation #COVID19 vaccines. Submit by May 26, 2023:
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@BARDA
BARDA
1 year
Through #ProjectNextGen , BARDA and @NIAIDNews are leveraging #PublicPrivatePartnerships to advance the development of MCMs, including vaccines & therapeutics, to better protect people in communities nationwide from current & future variants of SARS-CoV-2:
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@BARDA
BARDA
2 months
🆕 #ProjectNextGen opportunity under the @RRPV_Consortium . Interested in supporting the development of manufacturing technologies that can produce on demand vaccines & therapeutics against #COVID19 & other #HealthSecurity threats? Submit abstracts by 9/25:
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@BARDA
BARDA
5 years
Welcome @Hologic , our first #COVID19 diagnostics partner! The assay is being developed to detect SARS-CoV-2 on the Panther Fusion system & could be considered for Emergency Use Authorization by @US_FDA soon.
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@BARDA
BARDA
4 years
Coming soon! To address the growing threat of #AntibioticResistance , BARDA will be hosting a virtual workshop in early 2021 to better understand the AMR vaccine landscape of 4 targeted pathogens: E. coli (urinary), K. pneumonia, P. aeruginosa, & S. aureus. #WAAW
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@BARDA
BARDA
2 years
This #NationalPreparednessMonth , we’re recognizing the steps BARDA has taken to #BeReady to mitigate the impact of potential pandemic influenza viruses. W/ our partners, we work to provide timely, continuous updates of stockpiled vaccines...
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@BARDA
BARDA
6 years
We are excited to welcome our new German partners into the @CARB_X Accelerator Network! Together, we will support the early development of antibiotics, vaccines & diagnostics to combat drug-resistant bacteria.
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@BARDA
BARDA
2 years
Our partner @CARB_X is seeking vaccines, antibiotics, rapid diagnostics & other medical countermeasures to detect, prevent, or treat antimicrobial resistant bacterial infections. The deadline to submit is Jan 30, 2023 @ 23:59 ET:
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@BARDA
BARDA
3 years
Just Launched: Pediatric COVID-19 Data Challenge with @NCATS_NIH_gov , @HRSAgov , @NICHD_NIH . Help clinicians predict which among their pediatric patients will develop severe COVID-19 complications, including conditions like MIS-C. Read more:
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@BARDA
BARDA
4 years
The @US_FDA has issued EUA for @Moderna_tx ’s mRNA #COVID19 vaccine. Co-developed w/scientists at @NIAIDnews , BARDA, & Moderna, this innovative partnership has developed a safe & effective COVID-19 vaccine within a year. Read more:
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@BARDA
BARDA
1 year
Today at the #BLUEKNIGHT Symposium, BARDA and @JNJInnovation ( @JLABS ) announced the BLUE KNIGHT QuickFire Challenge: Accelerating Project NextGen. Applications due June 30, 2023. Learn more about the challenge and apply:
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@BARDA
BARDA
4 years
Take a behind-the-scenes look at medical countermeasure research, development & manufacturing programs that BARDA’s partners have undertaken to fight the #COVID19 pandemic! Join us as we embark on the #MakingCountermeasures series! Check back daily for updates.
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@BARDA
BARDA
1 year
Under #ProjectNextGen , BARDA seeks information on the potential use of “pull incentives” to drive #COVID19 vaccine development and commercialization, including in partnership with other sponsoring organizations. Respond to our RFI by 8/10:
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@BARDA
BARDA
5 years
BARDA is partnering with @Luminex to develop a rapid high-throughput #COVID19 diagnostic test to enhance capacity in hospitals across the country. Luminex Corp received @US_FDA Emergency Use Authorization on March 27.
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@BARDA
BARDA
5 years
BARDA continues our partnership with Cue Health to develop a portable diagnostic point-of care device connected to a mobile health platform to detect SARS CoV-2 to be considered for Emergency Use Authorization by @FDA .
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@BARDA
BARDA
2 years
📣 Our BID Day 2 Breakout Sessions will cover BARDA’s efforts in supporting the innovation and advancement of #medicalcountermeasure development and national preparedness. There will also be opportunities to connect with stakeholders about funding and possible partnerships.
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@BARDA
BARDA
5 years
BARDA is committed to innovation and the establishment of novel #publicprivatepartnerships . These new models enable us to bring the best ideas from the medical, scientific, biotech, and business communities to catalyze the #HealthSecurity field. #BIO2019 #PoweredByBARDA
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@BARDA
BARDA
5 years
A comprehensive study by BARDA, @CMSgov & Acumen LLC finds that sepsis is more common and costly than previously understood. Find out how the burden of #sepsis threatens everyday health, #HealthSecurity , and our economy. #SolvingSepsisTogether
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@BARDA
BARDA
4 years
#COVID19 can lead to viral #sepsis . BARDA is working with its partners on #SolvingSepsisTogether to help diagnose sepsis to #SaveLives and improve patient outcomes.
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@BARDA
BARDA
5 years
We are proud to partner with @nanomixinc to develop a rapid and accurate #COVID19 diagnostic for use in near-patient settings – with results in just 15 minutes
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@BARDA
BARDA
2 years
According to @WHO , antimicrobial resistance is one of the top 10 global public health threats. In this edition of the @ASPRgov Blog, BARDA’s Mark Albrecht & Christy Ventura explain how we are partnering with industry to develop new solutions to fight #AMR .
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@BARDA
BARDA
5 years
BARDA seeks a senior level biologist to serve as a project manager of a portfolio that includes medical countermeasures to address CBRN threats, influenza, and/or emerging infectious diseases, such as #COVID19 . Contract management experience desired.
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@BARDA
BARDA
4 years
A new Stewardship & Access Plan Development Guide, developed by @wellcometrust in partnership with @CARB_X , can help product developers strategize to facilitate faster & broader access to innovative antibacterials while fostering #antibiotic stewardship.
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