Vagheesh Narasimhan
@vagheesh
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Leading a group focused on AI + Genomics. Assistant Professor in the Departments of Integrative Biology | Statistics and Data Science @UTAustin
Austin, TX
Joined May 2010
Humans are the only bipedal great apes, due to the evolution of our unique skeletal form. What genomic regions underlie such change? Our cover article in @sciencemagazine led by @EucharistKun and in collab. with @tarjs is now out!
By combining data from full-body x-ray images and associated genomic data from more than 30,000 UK Biobank participants, researchers have provided new insights into the evolution of the human skeletal form. Learn more this week in Science:
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The duality principle in biology: A single human zygote contains all the information you need to develop into an adult human and at the same time contains within it, the evolutionary history of our species.
Interesting article from @WiringTheBrain that develops variational auto encoders (VAEs) as a metaphor for the relationship between genome and organism, with the genome corresponding to the compressed representation. I like the 'generative model' metaphor better than the 'blueprint' metaphor, although the genome also specifies part of the 'decoder', i.e. developmental program, so can't be reduced to the compressed representation. Genomes also encode different developmental programs for different cell types so the biological picture for a complex multicellular organism is much messier. But I like how this metaphor grasps at the mystery of how something as complex as an animal with a brain that produces specific behaviors can be reliably developed from a linear code of limited complexity.
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RT @Dr_RajeshGopal: New paper in @ScienceMagazine shows tiger distribution in India increased by 30% in the last two decades. It now suppor…
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RT @ScienceMagazine: This tigress has reclaimed the ancient fort within Bandhavgarh Tiger Reserve and made it her home. Protection, prey,…
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RT @NoonanLab: Out today in Cell: a comprehensive map of Human Accelerated Region gene targets in human and chimpanzee neural stem cells. T…
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Polygenic risk scores (which captures innate risk) and imaging (which captures acquired risk too) are both limited in predicting incidence for complex diseases. Glad that there's an NIH panel to discuss integratation of different data modalities -
Join the conversation on 3/11-3/12 to help the #NIHCommonFund prioritize opportunities in enabling #PrecisionMedicine with #AI through the integration of #MedicalImaging with other #Data types! Register today:
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RT @s_mccarroll: Excited to share the paper: Huntington's disease is a DNA process for almost all of a cell's life. Inherited HD alleles…
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AI is completely insane! (From the lab of this years winner of the Nobel prize)
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RT @_larsporsena: Our new paper is out! Congrats to the whole team, especially the staff and students @bournemouthuni who have been excavat…
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RT @FrankRHutter: #TabPFN v2 also excels on time series! Just before our Nature paper came out, we had this paper at the #NeurIPS time seri…
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RT @Tatsuya9JP: As requested by some; a more detailed version with relevant migration routes and contact events. I also added time and yDNA…
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