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Tarek
@tarekh247
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cryoEM associate | biochemistry faculty || FZEM | FUB | BIS
Berlin, Deutschland
Joined February 2019
And again, intriguing structures of the large ribosomal subunit @RainerNikolay
Excited to share our new work on the proline-rich antimicrobial peptide Api137, which disrupts large ribosomal subunit assembly and induces RNA misfolding. Big thanks to the Spahn & Hoffmann groups for this amazing collaboration!
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@HiCryoEM @Mark_A_Nakasone Keep us informed on the performance. Too few Apollos out there in the jungle yet.
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@BJ_Greber @OliBClarke @IsraelF96135088 @gonenlab @hervecelia @Guillawme 🍿 reliable, unbiased and resolution in one sentence 👀
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@OliBClarke @IsraelF96135088 @BJ_Greber @gonenlab @hervecelia @Guillawme 💯 agree. Look at your results, i.e. look at the map. The best resolution estimate of all.
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This is huge. Congrats Hauke and team.
Happy to share the results of a great collaboration with Thomas Pfannschmidt (LU Hannover), led by the amazing @paulafprado and Frederik Ahrens. Together, we determined the structure of the multi-subunit plastid-encoded RNA polymerase from chloroplasts! 🧵
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@BJ_Greber Same particles gave better reconstruction with blush? Changes in 3DFSC, SCF etc. for the reconstructions?
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@BJ_Greber Did you apply polishing in relion vs cryosparc? Would be interesting to compare refinement results of identical particle sets.
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