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Sameem Abedin
@sameem_abedin
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Leukemia/BMT Doc, dad, steeler fan(atic)
Milwaukee, WI
Joined November 2018
@Anand_88_Patel Caveat also these trials address transfusion dependent anemia. For symptomatic, but non transfused anemia, e.g. older LE-MDS patient with Hg hovering in the 9 range, many are treated, and think ESA still appropriate
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RT @Froedtert: We are proud of staff like Darryl Taylor, who works at Froedtert Hospital in Environmental Services. Darryl went the extra m…
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@MediHumdani Maybe you should be asking your friend to pay for private school. Guess it happens
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@Dr_AmerZeidan @sghmd Does any maintenance help, particularly those that come into HCT MRD negative? Think that’s included in data to come
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RT @hamcarless: every american president, but they're all cool and they all sport a mullet 46. Joe Biden
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@ReshmaRamlal2 @Dr_AmerZeidan @MediHumdani @LRunaas Iomab delivers myeloablative ablative radiation - more “intense” than FLAMSA or FLAG-Ida + NMA/RIC. These results are in line with historical outcomes doing ablative transplants in PIF - 10-15% durable CR. Most don’t transplant these pts, but nothing better exists too…
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@Dr_AmerZeidan If HCT improves OS, but doesn’t cure, would you not recommend HCT? That’s likely the case for TP53mut, monsomal/complex karyotype myeloid malignancies… it’s a concept I struggle with, I tend to say yes but it’s a valid question
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RT @MediHumdani: We at @MedicalCollege are looking for energetic faculty looking to build a career in HCT & CART therapy with a focus on my…
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@Dr_AmerZeidan @CanerSaygin Recent ASH presentation presented on pts who went to HCT with disease on D14 marrow. Some of those patients are probably in remission, or have chemo sensitive disease. Not the same as “active disease” in a traditional sense
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@MDPhD10 @CLachowiez @TalhaBadarMD Ratify enrolled when AML was 20%. I don’t know if this patient, esp with MLD is someone you can extrapolate from Ratify experience. RAEB-2 always at this age would get recommended HCT. Now, getting a little out there, some say that Ven is targeted therapy for NPM1, Ven-CLIA?
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@MDPhD10 @CLachowiez @TalhaBadarMD So for this NPM1+ AML - chemo and consolidation and no HCT? Comfortable with that?
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@drjgauthier @MediHumdani Losing ambition is one thing, the other is once a leader’s vision is implemented, things get stale
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