Robert Mahar
@robertkmahar
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Research biostatistician @unimelb @MCRI_for_kids @vicbiostat @austrim_cre | Interested in Bayesian decision making and adaptive trial design
Melbourne, Victoria
Joined June 2019
Consider #clinicaltrials randomising participants to prophylaxis and, upon failure, randomising to treatment. Can the randomisation be adaptively weighted in favor of the optimal interventions? 🧵@Katherine_J_Lee @bibhas1002 @asalim_hint @julieASimpson50
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Tragically, kids are often left out of #clinicaltrials. Not so for the @snap_trial, which brings data from adults and kids together using a sophisticated #Bayesian model. Our new statistical 'blueprint' details how we make it work (so you can too!).
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If you work on adaptive trials, our recent @BMJMedicine paper on the complexities of concurrent randomisation is a must read!
We developed a reporting framework for adaptive clinical trials. It uses the embedded fixed designs within an adaptive trial, which yield unbiased concurrently randomised cohorts. Paper is out in @BMJMedicine
@ascot_trial
@TrialsCentre
@austrim_cre
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Such a great lineup of invited speakers for our second conference! If you are interested in innovative trial methodology make sure to register! In person or online.
We're getting pretty excited to see all our invited speakers - just over a month to go! Contributed sessions will be announced shortly. Have you got your tickets yet? 🎫 Join us in Melbourne or online!
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@arthur_alb1 @f2harrell Relevant review of ordinal analyses in the 'big 4', led by @_chrisselman, should be published very soon!
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RT @MACHAustralia: Miss out on last week’s #EMCR Research Design Webinar? We got you covered! Catch up on an engaging presentation by Dr…
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@statsepi Sequential multiple assignment randomised trials (SMART) to the rescue! Chronically underused study design.
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Pre-print alert! For when you design #Bayesian adaptive #clinicaltrials with survival endpoints, but don't want to define a hazard functions 🤔 Try a general Bayesian approach!
Pre-print: A general #Bayesian approach to clinical trial design - Assessing whether a third dose of a vaccine improves protection against gastroenteritis in infants with Overstall, Jones and @robertkmahar
@QUTDataScience @DoE_S3Ri @Sydney_Uni @UniMelb
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@Trangucc @jazzystats We have a position open University of Melbourne/Murdoch Children's Research Institute. Lead your own methodological research, and design and analyse a Bayesian platform trial. Heaps of support from strong networks. Get in touch if you would like to chat!
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Improve the health of preterm kids as a #clinicaltrials manager for an innovative adaptive platform trial @MCRI_for_kids
We are seeking a Project Officer for the implementation of the PLATIPUS @PerinatalAPT to improve outcomes for preterm infants An exciting opportunity to be part of this new Adaptive Platform Trial @MCRI_for_kids based in Melbourne🇦🇺 #neoTwitter #neoEBM
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We are looking for a new postdoc biostatistician at @MCRI_for_kids in @Melbourne. Help design and analyse an innovative neonatal #Bayesian platform trial and develop new methods as part of @vicbiostat and @austrim_cre
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What an epic thread. Owned a few of these 😎
After the early bricks but before smartphones, there was a stretch where phone design went absolutely catshit bananas (1/?)
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New bling 👑 50 whole blood donations (in Australia at least). One of the few positives about having haemochromatosis (#ironoverload) is that I need to regularly donate @lifebloodau. Think about doing the same, it’s easy, you get free snacks, and it save lives!
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A great line “randomised care is better than random care”!
"Randomised care is better than random care". A/Prof @AshaBowen giving us a SNAP-PY @snap_trial summary including current SAB evidence at @ASIDANZ #ANZPID22. #IDTwitter #MedTwitter #infectiousdiseases @syctong @Josh_S_Davis
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@omaclaren @statsepi …domestic product? That’s more of a macroeconomic concept, I don’t know about them 🤷♂️
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