prionalliance
@prionalliance
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Non-profit organization devoted to funding scientific research towards a treatment or cure for human prion diseases.
Cambridge, MA
Joined November 2012
Sonia with our end-of-year update on developing a therapy for prion disease. Two new efforts from our lab: CHARM and divalent siRNA, and an update on the Ionis clinical trial. Support our work with a 1:1 matched donation through end of 2024.
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Our mid-year newsletter. The ASO is in the clinic and patients are really showing up. Sonia's TED talk, released today, pleads the case for prevention. Our most ambitious donation matching campaign yet. Let's do this!
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RT @cureffi: We long assumed increases in NfL always meant neuronal damage, and decreases in NfL meant amelioration thereof. The data we r…
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Beautiful, inspiring journalism by @meredithwadman -- the Hoffmans of Reed City, MI are our new heroes and we are so happy for their ray of sunshine!
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We've just updated our FAQ, which for years has said there are no ongoing trials in prion disease, to reflect that the first trial of a PrP-lowering ASO is now recruiting Trial posting: Ionis statement:
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Sonia with our semiannual newsletter. Human trials are finally around the corner. The outcome could be anything. It is the long view that gives us hope. A good time to remember the Stockdale Paradox.
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RT @slightchangepod: I first got to know Sonia Vallabh last year and am honored to call her a friend today. Her story has taught me so much…
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RT @cureffi: As promised, here is a new blog post unpacking what we know so far about the design of Ionis's upcoming PrProfile trial of ION…
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RT @OTSociety: Congratulations to Sonia M. Vallabh, Ph.D., and Erik Minkel, Ph.D., the winners of the OTS Paper of the Year Award - Basic R…
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Happy June! Here is our mid-year newsletter touching on the scientific progress from all corners that keeps us optimistic.
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RT @cureffi: If an ASO lowers target RNA 50% in bulk brain tissue, is it 50% in all cells or 100% in half? Are cell types all impacted equa…
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Our end-of-year newsletter: "We must be constantly vigilant, vocal, and feisty; we must be, to a judicious degree and at the right moments, trouble."
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In Part 3 of @NPRShortWave's series on prions, we describe our scientific strategy and the road to a cure — thanks @gabrielspitzer and @travlinscientst for working with us to tell our story!
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We are honored to tell our story in this episode of @NPRShortWave from @gabrielspitzer & @emilykwong1234 - part of a fantastic series they are doing on prions. 2nd half to come next week!
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RT @cureffi: To map the landscape of neurodegenerative disease clinical trials we analyzed 20 years of trial registrations. The paper: htt…
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RT @cureffi: Our first experiment, nearly a decade ago, was not the result we hoped for. But in hindsight, it gave us a valuable lesson on…
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