I-O breakthroughs at @UCLAHealth: Antoni Ribas, MD, PhD, Director of PICI Research Center at @UCLA, and @PuigSaus, PhD, PICI Investigator & 2020 Senior Parker Fellow, are developing novel precision treatments for challenging forms of malignant melanoma.

From Bench to Fireside is back! Join "the father of CAR T therapy" @carlhjune, Director of the PICI Center at @Penn, as he explores PICI's impact. From CAR T to future pioneers, don't miss his convo with PICI Chief Scientific Officer @John_E_Connolly.

New year, new episodes! PICI's podcast From Bench to Fireside is back later this month! Join our CSO @John_E_Connolly for conversations with i-o pioneers including @carlhjune, @EMittendorfMD, @RZappasodi, Toni Ribas & more. Catch up on episodes you missed:

For 8 years, PICI has united world-class researchers around our mission. In 2024, the PICI Network made groundbreaking discoveries, published key papers, received major awards & advanced life-changing new therapies. Explore The 2024 PICI Impact Report:

Key discovery: T cells lacking MED12 show reduced activation-induced cell death, offering new perspectives on cellular persistence and immune system regulation. Full study: (3/3)

Why it matters: For ~290K Americans diagnosed yearly, prostate cancer remains difficult to treat w/ immunotherapy. This study reveals cellular targets & potential markers to guide new treatments—& identify patients most likely to benefit. (3/3) Read more:

@Penn @JoeFraietta @EJohnWherry @EvanWeberPhD @ScienceAdvances This research fundamentally redefines how we can engineer CAR T cells, opening new therapeutic possibilities for cancers that have long resisted current immunotherapy approaches. (3/3)

We are thrilled to share the 2024 class of Representation in SciencE (RISE) Scholars, a group of seven exceptional researchers selected through our Diversity, Equity, Inclusion and Belonging (DEIB) Program. Read our latest blog:

PICI CSO John Connolly, PhD, discussed the latest immunotherapy trends at @sitcancer’s Annual Meeting over the weekend, with @bradloncar of @BiotechTVHQ. Check out the full interview to hear more from Dr. @John_E_Connolly at #SITC2024:

@UCSF @roybal_lab @Nature Congratulations to the team, including collaborator & Nobel laureate David Baker, PhD, Professor of Biochemistry & Director of @UWproteindesign at @UWMedicine, & Co-Founder of PICI portfolio company @Xaira_Thera! (3/3)

@Nature Led by Crystal Mackall, MD, Director of the PICI Center at @StanfordMed (@MackallLab), and PICI Project Member @michelle_monje, MD, PhD, this study exemplifies the impact of strategic collaboration in advancing new therapies. (3/3)