ondrugs
@ondrugsmedia
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Sterner Enmity of All Sham. Getting shit done.
Federal court
Joined February 2022
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Stay safe folks.
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@NYMag
@BellevueDoc
DEA denied my FOIA request on shortage communications. The denial is obviously unlawful. Let's see what happens.
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@CNN
I’m not sure if it is common practice for CNN to
link to a private citizens Dropbox who obtained those documents through a FOIA lawsuit without mentioning the name, but every other media outlet from
@nytimes
to
@MarijuanaMoment
has. It is unfortunate.
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Called my shot and swooshed it, baby.
#MSOGang
Plaintiffs lack standing and fail to state a claim.
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Down to the detail.
"Plaintiffs lack standing because they fail to allege that the CSA’s prohibition of marijuana activities has caused them any injury."
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@KevinSabet
Your orgs statement is nuts and completely misapprehends the CSA and the FDCA. As a lawyer, happy to explain them both to you.
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Glad our client is going back to work.
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Shane will post an analysis soon at , I think. Subscribe, if you want it.
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@tomangell
Lack of subject matter jurisdiction (no article iii cognizable injury / fear of prosecution), failure to state a claim (commerce clause, overruling Raich). Calling my shot
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@KevinSabet
@kylejaeger
@JohnFetterman
Why don’t you provide the factual basis for your testimony that “ 1 in 3 Americans who used in the last year according to all the studies fall under a cannabis use disorder or addiction.” I’m serious. I really want to know.
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@JulesEvans11
I continue to believe that better understanding adverse events is some of the most important work in psychedelics. Informed consent requires knowledge of risks/benefits.
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Can’t wait.
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DEA pulling DOI. May come back with “amended procedure.” Stay tuned.
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@LukeNiforatos
@learnaboutsam
@KevinSabet
Same to you guys. I found actual engagement with the issues to be refreshing. And believe it or not, we agree on much more than you may think.
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This is sensible. Skin in the game. But query whether
@US_FDA
can regulate the practice of medicine like this. Sounds like a window into future REMS here.
FDA's Tiffany Farchione says agency is “very concerned about subject vulnerability” during psychedelic sessions.
Referring to lead monitor requirements: “We want to make sure that somebody has their professional licence on the line when they’re in the room with that patient.”
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On Drugs : Australia Legalizes Medical MDMA and Psilocybin
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@BellevueDoc
Plan on writing about this soon. Not clear why amphetamine should be a schedule II drug, while benzos are schedule IV. Actually, amphetamine was originally schedule III (no quota) but moved in 1971. Some interesting history here. But hey, what do I know about drug law.
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To be crystal clear: Shane (
@admindotlaw
) and I litigated Sisley together, and those are arguments we jointly made on Sisley’s behalf.
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@RyanMarino
This type of logic and divisive rhetoric doesn’t move reform of drug laws forward and alienates potential allies. Exhibit A in why we can’t have nice things.
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@Drug_Researcher
The evidence for weightlifting and exercise for mental health is more robust (and cheaper!) than psychedelics. Also, we should be paying more attention to hormones as opposed to myopic focus on 5-HT, NMDA, etc.
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@KevinSabet
Are you referring to Carbonaro? . If so, what you are saying isn't true. Look at how they recruited. This was a survey *of those who have had challenging experiences* by psilocybin ("Participant recruitment"). I called you out on this earlier in the year.
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@unusual_whales
Nothing nefarious here. Told my subscribers of the news on Thursday and Friday last week.
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President Biden's Scheduling Directive Is a Game Changer on On Drugs
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@KevinSabet
Kevin,
You testified that "1 and 3 Americans who used in the last year according to all the studies fall under a cannabis use disorder or addiction."
What "all the studies" are you talking about?
(Agree with you on gummies/candies)
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@D__Nickles
So while I share concerns about the quotes, I think you are unfortunately omitting some essential context. Under the PREA, the FDA can require pediatric studies of a drug.
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@NeseLSD
Could not agree more. The best way at countering prohibitionists is to be scrupulously honest and principled.
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True
@michaelpollan
, more than most, made the subject of psychedelics accessible. But this take by
@ZappyZapolin
on
@TheDalesReport
is uninformed and sadly diminishes contributions of a cast that worked tremendously hard to get an unprecedented result.
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@alwaysLTfocus
@LogicPrevails_
@admindotlaw
Probably, yes. But I can’t tell you what someone else means. But based on Epidiolex, rescheduling down to 5 could be accomplished.
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@Psyched_Alpha
@calyxlaw
@emergelawgroup
Amazing resource, and linked well. Interesting re: Denmark. And a great refutation of anti-decrim talking points, at least when done in other cultures.
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@ggreenwald
@GreekPuppyQueen
One could support free speech/expression and not believe in the same without consequences, right? Put another way, I can defend the right of these folks to march in Skokie without believing that those who do should not suffer consequences of their exercising 1A rights.
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@JulesEvans11
Once again, great original work having actual real world effects. You argue for "[r]egulatory systems that improve access to the benefits of psychedelics while minimizing the harms." So here is my next question.
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@mycopreneur
This is correct. It is also far easier to get to the Bahamas from Florida. You can go back and forth in a day.
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@Josh__Hardman
Wonder if they'll give out free ketamine to laid off Field Trip employees. Thoughts?
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@TheBorisLab
I suspect this will be one of the most important studies and question going forward for ketamine and all psychedelic assisted therapy. I think expectation makes some sense b/c of neuroplasticity.
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"Erudite."
10/10 flirting
I find US cannabis folk generally less cognizant of how federal drug policy is constrained by the UN Single Convention.
Fantastic explainer by the erudite
@ondrugsmedia
team.
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A bit confused since, according to the statute,
@US_FDA
accepts applications "with respect to any drug" and not applications "with respect to any drug assisted therapy."
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@calyxlaw
@mattbagg
@tfeller
@Psyched_Alpha
@NoahJSmith98
@joannakempner
My issue is that the Sewell patent goes broader than 2-Bromo with a "substantially pure form" of LSA. "Substantially pure form" may not have been disclosed in prior art. But LSA to treat cluster headaches was definitely disclosed (e.g., clusterbusters)
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@D__Nickles
@SashaSisko
@PsychedelicWeek
@Psyched4News
@MasonMarksMD
And not just therapeutic intervention--but a state regulated (but federally illegal) "psilocybin services" model capable of delivering a therapeutic intervention on more equitable terms than pharma. Fake bill of goods.
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@JulesEvans11
Good article. What I'd add is the whole reasoning behind these regulated access systems was to guard against these types of stories. And yet, as you point out, he went to Portland, got mushrooms, and it happened anyway.
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On Drugs : A Wake-up Call from Down Under
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On Drugs : Two Simple Tricks to Study Dispensary MJ Now
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@KevinSabet
@ErnestoLon
I do have to admit: “California sober” always strikes me as similar to “half pregnant.”
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@KevinSabet
Said it six months ago, and I’ll say it again: the marijuana legalization movement, from a social justice standpoint, is a failure.
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@diterpene
@Serotonin2arec
@EikoFried
@RussellHausfeld
Sure
@diterpene
. First, as an attendee, let me object to the notion that this was a psychedelic pharmaceutical conference. I do agree with other points being made. As to bifurcated rescheduling, the answer is that rescheduling will probably be bifurcated.
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@JulesEvans11
Two brilliant economists (I've worked with one) look at legal weed markets and conclude that regulation isn't always so great. These guys should be on the rolodex of the architects of the psilocybin boondoggles.
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@TheBorisLab
@TheresaLii
To be clear, "placebo" here is a group being administered anesthesia, including anesthetics with well-known psychotropic properties?
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@geraldposner
@KevinSabet
I think highly of your book, but nobody is rushing spend the money needed to do clinical trials of racemic. Hence, Spravato. Off-label use is pretty standard way to discover and grow new applications of medicine. As long as patients are informed of risks.
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@mycopreneur
LSA is a depressant according to the CSA. But your point is valid. There's no real definition about what it means to be a "psychedelic."
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@therealbrom
To more substantively answer your question, I don’t know. It has caught some shade from the research community, but has been consistently reported to have hallucinogenic effects.
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@mycopreneur
@baystaters
Waiting for your Ft. Lauderdale psilocybin yacht/flotilla short. Bonus points if you say "flotilla" 30 times.
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Breakups are hard, but can be for the best.
But don't worry, we're still friends. (Right Shane?)
Pennington Signing Off
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@Josh__Hardman
@atai_life
@flobrand
@C_Angermayer
deserve hefty praise for that submission. Even if self-interested—and that isn’t clear—it is courageous and correct. Actively engaging regulators is an important part of how medical psychedelics should transition to a mature industry.
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@JulesEvans11
Oregon, for example. I mean, is it safer to have a regulated "non-medical" system where folks are openly parading around medical claims? And when the ticket to entry is unaffordable, folks will turn to illicit market. We know that from cannabis.
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@Peter_Grinspoon
Do you have any evidence or study to support the smoke twice as much? There's been a lot of psychology done on choice and limiting size. Remember the NYC soda ban? I just don't think it is that simple to say capping limits will result in folks smoking twice as much.
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An Open Letter to Governor and Former DEA Administrator Asa Hutchinson on On Drugs
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@RyanMarino
This is such an idiotic take, it is hard to read. Drugs modify behavior and inhibition, sometimes removing the restraints holding back terrible impulses. Call that what you will, but drugs do make people do bad things from a causality standpoint.
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@SashaSisko
@D__Nickles
I’m not a physician or scientist, but treating a child traumatized by environmental factors (and potentially reinserting the child into that environment( has to be different from treating childhood trauma in an adult, or isolated trauma in an adult.
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On Drugs -- GHB and REMS: A Regulatory Love Story (Part 3)
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@btkanalyst
@DrMattYoungPhD1
@therealbrom
Tons of IP. . Just a few issued patents shy of 100. Even by pharma terms, that's a lot.
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On Drugs -- Recent On Drugs Developments: A Note of Gratitude
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@diterpene
@RussellHausfeld
@Serotonin2arec
@EikoFried
On a percentage basis Microdose, Benzinga, many others. Even the psychedelics track at SXSW. As someone who goes to these live in the flesh, it isn’t even close.
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On Drugs : Garbage from NYU Langone
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@TheBorisLab
Thanks for this. Very interesting study. This is my issue though: if these other anesthetics have antidepressant properties at the lower doses then it is hard to draw conclusions, right, except that other anesthetics may be as effective.
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