We are a lucky lab! We are so grateful to have been able to work with
@freejakoba
for almost 8 years! 🥰 Such a blast! Thanks so much, Michelle, for everything! Not only the lab, but the whole Institute will miss you! All the best in your new adventure!
@IBE_Barcelona
I just learned that my younger daughter has explained to her teacher & class that I did not get a grant (
@ERC_Research
) & that she was so happy because I will have more time for her 🥰🥰 And you know what? I agree! So let's celebrate I have not ERC! 🥳
#family
#academialife
We will not be able to understand how animals originated without unravelling the whole diversity of animal's relatives. MISSINGRELATIVES will try to get those lineages that are out there (& we know nothing!)& see what they tell us. I can't wait to get them!
#ERCAdG
@ERC_Research
I like this paper! The
#genome
of the Australian lungfish shows pre-adaptation of limb-regulatory programs before conquest of land and posterior co-option. Somehow similar to what we see in multicellularity origins
@nature
Facing challenges in research funding, salaries, and working conditions in Spain can be tough. But what's priceless? The chance to visit my 100yo grandma every week! 🌟 It's all about priorities, about what truly matters.
#GrandmaPower
#WorkLifeBalance
The image says it all. Our view of metazoan-specific genes has dramatically changed in just 14 yrs. New genome data from diverse unicellular relatives of animals has been crucial. Broad taxon sampling has been the mantra of the lab and will continue to guide us in the future.
The 12th PhD of the lab is coming!! Aleksandra is ready to show all her great work on developing genetic tools in several unicellular relatives of animals. Looking forward to the defense!
#animalorigins
#phd
#phdlife
You can not understand how animals originated if you do not know the nature of two ancestors: the unicellular ancestor of animals & the last common ancestor of animals. That's why we are committed to getting an accurate reconstruction of both of them.
#ourgoal
#labresearch
Our view on the importance of
#protists
and why we should care and study them, now published in
@IyC_es
with
@mferrerbo
Protists represent 3% described species, but genetic analyses show otherwise. A bias in our knowlege that needs our attention
#biology
Our team is on a mission to find the 'Magnificent 8'-eight elusive lineages closely related to animals but yet to be discovered.
eDNA data suggests this glacial Spanish lake may harbor some of those "known unknown" relatives. So, here we are!
Could this serene spot hold the key
Of all biological disciplines, I believe taxonomy is the one with the highest potential for long-term scientific rewards.
One single species can shatter previous conceptual frameworks of several disciplines.
That’s all you need. Just 1 taxon. Only
#taxonomy
has this super-power
Apologies to editors, colleagues, members of the lab...for taking so long to answer your requests and emails... The truth is that there are some small creatures here that use much more convincing and persistent tactics to get my attention than any of your emails...
#childrenpower
Our current reconstruction of the genetic content of the unicellular ancestor of animals. I can not insist enough, had not we studied filastereans, ichthyosporeans, corallochytreans & choanoflagellates, the story will be completely different. Different & inaccurate
#animalorigins
The last eukaryotic common ancestor (LECA) was..LECA lived...LECA had..., but what is LECA? an ancestral single cell? a population? a concept? and, why not a pangenomic population? see our view
@NatureEcoEvo
with
@Jgwideman
@freejakoba
& O'Malley
#protists
🔬🦠We are unlocking the secrets of animal origins! Meet Creolimax fragrantissima, a stunning single-celled organism closely related to animals. This
#ichthyosporean
shares fascinating genes with animals & is one of the few that offers genetic tools for research. Want to study
Great opinion piece on
#multicellularity
, key innovations & genetic drift, suggesting evolutionary priority effects for animals evolving once. The discussion is truly insightful, but I fear we often underestimate the uncertainty in this field. For example, unknown taxa are
The morphogenetic processes of unicellular holozoans resemble those of animals. But, can they tell us something about the origin of animal
#embryology
? We think so and we believe
#ichthyosporeans
are well positioned to address this!
#evodevo
#multicellularity
Was the origin of metazoans a black swan event? Will we ever be able to elucidate what happened with our current taxon sampling? Are we missing key taxa? All this and more
@AnnualReviews
with
@Elenacleomina
@koryu_kin
I believe the best way to lead is to let those around you to flourish, to bloom, while you remain quiet on the back. Just there in case it is needed.
I have no doubt about that. Your lab will do much better. Your people will grow faster and bigger. They will feel safe.
1/3
As every Christmas during the last 25 years, the great Marta
@RiutortLab
invites all previous and current PhDs for dinner. What a mentor she is! Here with
@CarranzaLab
, her 1st PhD student. Thanks Marta!!
Microbial eukaryotes are important, but often overlooked, organisms in the global ecosystem. A Resource, supported by a community effort, describes valuable transformation tools for marine protists that have been challenging to genetically manipulate.
Chapter 9 moves us into the domain of clonal multicellularity. Here,
@freejakoba
and
@multicellgenome
take on the Herculean task of examining the many independent origins of clonal multicellularity. This is our longest chapter (for good reason!). 19/32
Thrilled this is out! Fruit of a wonderful collaboration with Núria Ros-Rocher &
@multicellgenome
Chemical factors induce aggregative multicellularity in a close unicellular relative of animals | Proceedings of the National Academy of Sciences
Aggregative
#multicellularity
has been described in a few taxa but it is present in all eukaryotic superclades. It seems like an uncommon type of multicellularity. Yes, it does. However, I bet it will be less and less uncommon the more we study different
#protists
along the tree.
Animals and Fungi. So phylogenetically close & so different. Why is that? 4 novel holozoan
#genomes
& the fantastic work of Edu & col have nailed down the reasons for that. It is all about the past. Read the paper or... wait for Edu’s twitter thread to know more 😉
@nature
Marta
@MRiutortUB
was one of my two PhD supervisors. By her example I could see how you could put people first, papers second, and still be highly productive. A great example to me, an incredible mentor, and a wonderful friend and colleague. Thanks Marta!
Once more genomes of unicellular relatives of animals key to decipher
#animalorigins
. They seem to have relicts of metazoan chromosomal units. Interesting results! However,
#Capsaspora
is NOT an
#ichthyosporean
!🙏
After 14 yrs, I have ended my teaching assistant contract
@GeneticsUB
. Giving classes at the masters was the highlight of the year for me. One of the best moments. But, sometimes, you need to say no to the things you really, really enjoy. Thanks
@GeneticsUB
for all!
New study reveals surprising twists in
#dinoflagellate
evolution! Photosynthesis lost 21 times, novel bacterially-derived histone-like proteins (HLPs) & several independent acquisitions of kleptoplastic species. Congrats
@weeseamonsters
& all authors!
#Evolution
#protists
Our big dinoflagellate paper is out! Highlights include transcriptomes for 39 heterotrophic species and new insights into character evolution of notable traits, like chromatin packaging proteins and rhodopsins. Enjoy!
Once more, it seems the
#archaeal
ancestor of eukaryotes was more complex than previously thought! 😀 (reminds me of the unicellular ancestor of animals). In this occasion, it is the use of de novo protein structure modeling & sensitive sequence similarity algorithms that helped
Our latest: Using de novo protein structure prediction and sensitive sequence searches we found many new eukaryotic signature proteins in Asgard archaea, suggesting the archaeal ancestor of eukaryotes was more complex than previously assumed.
@koestlste
One of animal's closest relatives (
#Capsaspora
) creates temporal multicellular structures by cell aggregation. What triggers them, how are they made, and whether they could have had any role in animal origins are questions that we aim to resolve.
#animalorigins
We are absolutely delighted to welcome Jennah (
@Jennah_E_D
) as she joins our lab! With a postdoctoral grant from
@Vetenskapsradet
, she will delve into the captivating realm of
#microbial
interactions and their impact on the origin of animals. Exciting times ahead!
#AnimalOrigins
One of my dreams was that one day I will be able to work close to either Nicole
@A_Nicole_King
or Dan
@balkalarre
from
@Choano_Lab
and learn from them. The day has arrived! Dan's new office is just besides mine at
@IBE_Barcelona
!! Nicole, wouldn't you like to join the party? 🙏😉
Heads up! The
#MSCA
Postdoctoral Fellowships 2024 call opens in April. 🔍 Start your journey early by exploring potential host organisations now and gear up to craft the perfect proposal! 🌟 🎓🔬
More info and opportunities this way ➡️
Very good news! Cédric Berney joins the hunt for the Magnificent8 relatives of animals! Cédric will be our 18S rDNA expert, as he knows by heart the 18S of each of the 8 missing lineages. Wellcome to the lab, Cédric!
#multicellularity
#magnificent8
#animalorigins
@IBE_Barcelona
And here's Abeoforma whisleri, the second
#ichthyosporean
we have equipped with genetic tools! This amazing organism shares many genes with animals & has fascinating cell biology, offering insights into animal evolution. 🧬🔬
#multicellularity
🔬🦠We are unlocking the secrets of animal origins! Meet Creolimax fragrantissima, a stunning single-celled organism closely related to animals. This
#ichthyosporean
shares fascinating genes with animals & is one of the few that offers genetic tools for research. Want to study
Very sad. Huge loss. Jose Luis not only taught me (and people from my lab) many things, but he made me laugh almost all the time, and he influenced my research and my science in many ways with his enthusiasm. Great, amazing person. Our thoughts are with his family.
With all our sadness, today we lost our colleague & friend! Jose Luis (
@jlgomska
) was one of the pioneer researchers of the CABD when it was only a dream. His energy and perseverance made this dream real. He is gone well before his time....
My friend & planarian-researcher Emili Saló from
@GeneticsUB
already told me 20 yrs ago: "If you listen to your children and get a dog, you need to know that YOU will be the one walking it EVERY morning". As usual, he was right....😂
Only a taxon-wide functional platform will allow us to address animal origins. Yes, taxon-wide! That was our mantra
@Elenacleomina
@SebasNajle
For 15 years! Now, the mantra is real. Now the platform is here! Now, season 3 begins! 1/3
Our mission to find the 'Magnificent 8' continues!
Eight elusive lineages closely related to animals but yet to be discovered.
eDNA data suggests the Mediterranean coast harbors some of those animal relatives. So, this week Rubén, with the help of Maria from
@RJBOTANICO
went to
Groundbreaking study by
@andrewjroger
, Yana, Alastair & co. on 'Meteora sporadica'! They unravel a stunning eukaryotic lineage that reshapes our understanding of
#protist
diversity. A reminder of the unexpected diversity in
#eukaryotic
life! congrats!
#evolution
#protists
Not only bacteria, also red algae, through a polysaccharide seems to induce multicellular development in the choanoflagellate Salpingoeca rosetta. Nice to see the diversity of biochemical interactions that produce multicellular behaviour on
#choanos
. Congrats
@dsboothacosta
&
Stable transformation of the enigmatic holozoan Corallochytrium limacisporum — finally out in the open!
From Aleksandra Kożyczkowska, Sebastián Najle,
@eduocapa
, Cristina Aresté,
@multicellgenome
&
@Elenacleomina
.
Exciting new research that suggest the archaeal-eukaryotic ancestor had the capacity for aerobic respiration, maybe providing energetic advantages during early eukaryogenesis! Nice to see so many new Asgardarchaeota metagenome-assembled genomes (MAGs). Congrats to the
After many years of work we present a preprint that doubles the numbers of Asgard genomes, revealing lots of new insights into their metabolism. Notably, lineages closely related to eukaryotes are capable of aerobic respiration!
@katy_appler
@val_deanda
yeah! a new
#protist
closely related to animals! Great work by
@pjkeelinglab
@CurrentBiology
A pity its phylogenetic position is unclear-but no worries, already running our own trees 😉
Nicole King
@Choano_Lab
closes the
#choanomeeting19
with a call for collaboration, not competition. My impression is that is that we have & we need to keep it this way. Integrating other unicell relatives of animals into the community will surely strenghten it!
#collaboration
What a fantastic day! A big thank you to
@PSuarezAra
for an incredible 4 years of PhD research pursuing the establishment of genetic tools in
#ichthyosporeans
&
#corallochytreans
! Thanks to
@SebasNajle
for co-supervising with such knowledge and enthusiasm. Thanks Núria Ros i
“We don’t really know if it’s an animal, if it’s a fungus, if it’s in between,” What??? it is a
#protist
!! And nice and interesting as most protists. Anyway, happy Physarum made it to a zoo! 😏
Diving into the microscopic world in the book 'Hallo Plankton' 🌊🔬! happy to have been a small part of this journey alongside illustrator Kristina Heldmann together with
@Guse_Lab
& others. Kristina has made an amazing work to show the beauty of plankton through art!
Our aim is to break the huge knowledge asymmetry that has existed between animals and their unicellular relatives for far too long. We have done a lot, specially at the level of genomes. But, we can do more, and we’re committed to doing more!
#multicellularity
#animalorigins
Once more, proteins & protein domains previously thought to be animal-specific are present in their unicellular relatives. In this case, proteins involved in cell-cell contact formation such as ERM and merlin; by Shabardina & others
@OfficialSMBE
#protists
Three decisions will be crucial when starting your lab: 1) what to investigate (line of research), 2) where (institution/university/city/country), & 3) with who(the team). I would argue that 2 & 3 are the more important ones. A bad decision in those can really affect your career.
The
#nitroplast
, a potential new organelle resulting from a
#symbiosis
between a nitrogen-fixing bacterium and an alga. The result is an adaptation of the microalgae Braarudosphaera bigelowii to nitrogen-limited waters. As
@RMassanaM
mentions in his nice comment
A nitrogen-fixing organelle, or “nitroplast,” has been identified in a marine alga. This discovery sheds light on the evolutionary transition from endosymbiont to organelle.
Learn more this week in Science:
New article show siphonophores exhibit a broad range of nuclear genome sizes suggesting significant genetic diversity within this group. In contrast, mitochondrial gene order seems conserved among
#siphonophores
! I wonder what evolutionary pressures led to their variation in
Amazing cover featuring a fascinating cell behavior of a ciliate! 🦠✨ Times are changing! These discoveries and these poorly-known organisms, once mostly confined to specialized journals, are now hitting the mainstream. Exciting times for
#protist
research! Congrats
@PrakashLab
The tiny predator Lacrymaria olor owes its shape-shifting ability to an “origami-like” cellular architecture, a new Science study finds. The results offer a glimpse into geometrical control of behavior in single cells.
Learn more in this week's issue:
A great example of the importance of taxon sampling to understand evolutionary transitions & the relevance of the environment & the adaptations of single-cell organisms to the posterior acquisition of
#multicellularity
. Great work by
@CKCornwallis
@CoelhoSvensson
@krengefors
etal
#Choanoflagellates
mutants that aggregate promiscuously into amorphous clumps. The genes involved are glycosyltranferases. Maybe capacity to aggregate is not that unusual among unicell relatives of animals? Great paper by
@Choano_Lab
in
@elife
#research
In
#BMCEcolEvol
, researchers
@UofNorthFlorid
investigate the body plan evolution of tardigrades and find that loss of Wnt genes may be related to their simplified development, anatomy and miniaturization. To learn more, visit <>.
@chico_snake
Bidding a heartfelt farewell to our dear
@koryu_kin
after an incredible 4 years together. 🌟 Your contributions to
#holozoans
research and our lab's spirit have been invaluable. Wishing you all the success and groundbreaking discoveries ahead in Japan! 🥰🥰🥰
#team
#academialife
"It turns out that the length of the reads (from MinION) over-competes the randomly generated sequencing errors and brings accurate phylogenetic information." This is music to my ears....
#longread
#biodiversity
#metabarcoding
Great work!
So grateful for the phenomenal women in our lab. Their leadership & generosity pave the way for a more inclusive science & they make our lab better. A pity their path remains unfairly steep.
#WomenInSTEM
#InternationalWomensDay
🔬🦠☢️We love crazy ideas!.... specially if potentially relevant to address the origins of animals. Check out our new experimental evolution project with one of our beloved
#ichthyosporean
, a close unicellular relative of animals; collaborating with
@labsubcanfranc
.
Days like this compensates for others kinds of days. Nice to see Aleksandra defend so well her PhD!! 💪 So grateful for having done this path with
@Elenacleomina
🙏 Thankful for committee members Cristina Grande, Drahomíra Faktorová &
@balkalarre
#phdlife
#PhDone
#animalorigins
Such a nice day yesterday! Núria, a previous PhD student, came back to the Institute to give an
@IBE_Barcelona
seminar and she got a rockstar welcome!
It wasn’t just for her impressive science on
#choanoflagellates
(now at
@thibaut_brunet
's lab) but also for the lasting positive