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Iñaki Ruiz-Trillo Profile
Iñaki Ruiz-Trillo

@multicellgenome

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Leading a research lab with Elena Casacuberta at @IBE_Barcelona . We aim to unravel how unicellular organisms evolved into #multicellular animals.

Barcelona
Joined April 2013
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@multicellgenome
Iñaki Ruiz-Trillo
1 month
We are a lucky lab! We are so grateful to have been able to work with @freejakoba for almost 8 years! 🥰 Such a blast! Thanks so much, Michelle, for everything! Not only the lab, but the whole Institute will miss you! All the best in your new adventure! @IBE_Barcelona
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@multicellgenome
Iñaki Ruiz-Trillo
5 years
I just learned that my younger daughter has explained to her teacher & class that I did not get a grant ( @ERC_Research ) & that she was so happy because I will have more time for her 🥰🥰 And you know what? I agree! So let's celebrate I have not ERC! 🥳 #family #academialife
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@multicellgenome
Iñaki Ruiz-Trillo
1 year
We will not be able to understand how animals originated without unravelling the whole diversity of animal's relatives. MISSINGRELATIVES will try to get those lineages that are out there (& we know nothing!)& see what they tell us. I can't wait to get them! #ERCAdG @ERC_Research
@IBE_Barcelona
Institute of Evolutionary Biology (IBE)
1 year
📣Congratulations to @multicellgenome for his ERC Advanced Grant!👏👏 Iñaki Ruiz-Trillo is a PI of @IBE_Barcelona ( @CSIC - @UPFbiomed ) and has been awarded one of the most prestigious grants from the @ERC_Research for the "MISSINGRELATIVES" project.🧵 #UnravellingEvolution #ERCAdG
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@multicellgenome
Iñaki Ruiz-Trillo
4 years
I like this paper! The #genome of the Australian lungfish shows pre-adaptation of limb-regulatory programs before conquest of land and posterior co-option. Somehow similar to what we see in multicellularity origins @nature
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@multicellgenome
Iñaki Ruiz-Trillo
7 months
Facing challenges in research funding, salaries, and working conditions in Spain can be tough. But what's priceless? The chance to visit my 100yo grandma every week! 🌟 It's all about priorities, about what truly matters. #GrandmaPower #WorkLifeBalance
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@multicellgenome
Iñaki Ruiz-Trillo
3 years
The image says it all. Our view of metazoan-specific genes has dramatically changed in just 14 yrs. New genome data from diverse unicellular relatives of animals has been crucial. Broad taxon sampling has been the mantra of the lab and will continue to guide us in the future.
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@multicellgenome
Iñaki Ruiz-Trillo
3 years
The 12th PhD of the lab is coming!! Aleksandra is ready to show all her great work on developing genetic tools in several unicellular relatives of animals. Looking forward to the defense! #animalorigins #phd #phdlife
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@multicellgenome
Iñaki Ruiz-Trillo
3 years
You can not understand how animals originated if you do not know the nature of two ancestors: the unicellular ancestor of animals & the last common ancestor of animals. That's why we are committed to getting an accurate reconstruction of both of them. #ourgoal #labresearch
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@multicellgenome
Iñaki Ruiz-Trillo
1 year
A workflow for taxonomic detection by long-read #metabarcoding using @nanopore MinION. #longread #biodiversity @biorxivpreprint
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@multicellgenome
Iñaki Ruiz-Trillo
6 years
Our view on the importance of #protists and why we should care and study them, now published in @IyC_es with @mferrerbo Protists represent 3% described species, but genetic analyses show otherwise. A bias in our knowlege that needs our attention #biology
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@multicellgenome
Iñaki Ruiz-Trillo
4 months
Our team is on a mission to find the 'Magnificent 8'-eight elusive lineages closely related to animals but yet to be discovered. eDNA data suggests this glacial Spanish lake may harbor some of those "known unknown" relatives. So, here we are! Could this serene spot hold the key
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@multicellgenome
Iñaki Ruiz-Trillo
4 years
Our work #Capsaspora #integrins now on @CurrentBiology we suggest integrin-mediated adhesion pre-dated origin of animals! Work with @dudin_o @Elenacleomina   @nickbrownlab & Helena & Matija part of @erc_research  grant  @IBE_Barcelona #protists   @GeneticsUB
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@multicellgenome
Iñaki Ruiz-Trillo
3 years
Of all biological disciplines, I believe taxonomy is the one with the highest potential for long-term scientific rewards. One single species can shatter previous conceptual frameworks of several disciplines. That’s all you need. Just 1 taxon. Only #taxonomy has this super-power
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@multicellgenome
Iñaki Ruiz-Trillo
4 years
Our review #animal origins-we differentiate & describe what we know about 2 ancestors: the last unicellular ancestor of animals & last common ancestor of animals with Núria @a_pposada @freejakoba @IBE_Barcelona @GeneticsUB #protists @RSocPublishing
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@multicellgenome
Iñaki Ruiz-Trillo
3 years
Cell differentiation and morphogenesis in a 1 billion-year- old #multicellular fossil! @CurrentBiology . Could Bicellum brasieri be assigned to #ichthyosporeans or #corallochytreans ? They certainly look very similar, but..who knows...
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@multicellgenome
Iñaki Ruiz-Trillo
4 years
Apologies to editors, colleagues, members of the lab...for taking so long to answer your requests and emails... The truth is that there are some small creatures here that use much more convincing and persistent tactics to get my attention than any of your emails... #childrenpower
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@multicellgenome
Iñaki Ruiz-Trillo
3 years
Our current reconstruction of the genetic content of the unicellular ancestor of animals. I can not insist enough, had not we studied filastereans, ichthyosporeans, corallochytreans & choanoflagellates, the story will be completely different. Different & inaccurate #animalorigins
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@multicellgenome
Iñaki Ruiz-Trillo
5 years
Glad to have our paper published in @eLife . Unicellular relatives of animals continue to provide more and more surprises! @dudin_o @xgraubove @___JonB___ @IBE_Barcelona @IRBioUB #protists #animalorigins #icthyosporeans #multicellularity
A unicellular relative of animals generates a layer of polarized cells by actomyosin-dependent cellularization #protists by @multicellgenome
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@multicellgenome
Iñaki Ruiz-Trillo
6 years
The last eukaryotic common ancestor (LECA) was..LECA lived...LECA had..., but what is LECA? an ancestral single cell? a population? a concept? and, why not a pangenomic population? see our view @NatureEcoEvo with @Jgwideman @freejakoba & O'Malley #protists
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@multicellgenome
Iñaki Ruiz-Trillo
5 months
Are #choanoflagellates , #filastereans , #ichthyosporeans & #corallochytreans truly the best models for exploring animal origins? While these lineages have been so far pivotal to address the origin of animals (and they surely will continue to be!!), eDNA has revealed that there
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@multicellgenome
Iñaki Ruiz-Trillo
3 months
🔬🦠We are unlocking the secrets of animal origins! Meet Creolimax fragrantissima, a stunning single-celled organism closely related to animals. This #ichthyosporean shares fascinating genes with animals & is one of the few that offers genetic tools for research. Want to study
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@multicellgenome
Iñaki Ruiz-Trillo
1 month
Great opinion piece on #multicellularity , key innovations & genetic drift, suggesting evolutionary priority effects for animals evolving once. The discussion is truly insightful, but I fear we often underestimate the uncertainty in this field. For example, unknown taxa are
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@multicellgenome
Iñaki Ruiz-Trillo
6 months
The morphogenetic processes of unicellular holozoans resemble those of animals. But, can they tell us something about the origin of animal #embryology ? We think so and we believe #ichthyosporeans are well positioned to address this! #evodevo #multicellularity
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@multicellgenome
Iñaki Ruiz-Trillo
4 years
Our analysis of metabarcoding data from Tara Oceans now out  @OfficialSMBE with @AliciaSArroyo   @aire_team @romainJSBLannes We identified a potential novel group of holozoans #protists   @IBE_Barcelona   @GeneticsUB @protistologists   @ISEPprotists
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@multicellgenome
Iñaki Ruiz-Trillo
1 year
Was the origin of metazoans a black swan event? Will we ever be able to elucidate what happened with our current taxon sampling? Are we missing key taxa? All this and more @AnnualReviews with @Elenacleomina @koryu_kin
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@multicellgenome
Iñaki Ruiz-Trillo
3 years
I believe the best way to lead is to let those around you to flourish, to bloom, while you remain quiet on the back. Just there in case it is needed. I have no doubt about that. Your lab will do much better. Your people will grow faster and bigger. They will feel safe. 1/3
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@multicellgenome
Iñaki Ruiz-Trillo
7 months
New comparative genomic analyses by @JvHooff , @EelcoTromer , @eme_laura reveal the last eukaryotic common ancestor (LECA) possessed all 4 SMC complexes. Condensin II lost at least 30 times across #eukaryotes ! Congrats! 👏 #evolution
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@multicellgenome
Iñaki Ruiz-Trillo
4 years
Our view on the origins of animal development and how unicellular relatives of animals can help decipher it. With @deMendoza_Alex #multicellularity #development #animals #evolution @Dev_journal @IBE_Barcelona @GeneticsUB
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@multicellgenome
Iñaki Ruiz-Trillo
7 months
Just a normal morning, checking how is the #Mediterranean Sea doing before heading to work. In 10 minutes back to the computer! 😅. #nofilters
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@multicellgenome
Iñaki Ruiz-Trillo
4 years
We are finally trying @nanopore ourselves! More #protists genomes! Let's hope it works! #nanopore #genome #genomesequencing #evolution #animalorigins
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@multicellgenome
Iñaki Ruiz-Trillo
8 months
As every Christmas during the last 25 years, the great Marta @RiutortLab invites all previous and current PhDs for dinner. What a mentor she is! Here with @CarranzaLab , her 1st PhD student. Thanks Marta!!
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@multicellgenome
Iñaki Ruiz-Trillo
4 years
A huge research effort to provide emerging models along the tree of eukaryotes to the community. Glad to have this published and happy to have contributed with @Elenacleomina with one of our taxa #protists #emergingmodels @IBE_Barcelona @GeneticsUB @SINGEK_ITN
@naturemethods
Nature Methods
4 years
Microbial eukaryotes are important, but often overlooked, organisms in the global ecosystem. A Resource, supported by a community effort, describes valuable transformation tools for marine protists that have been challenging to genetically manipulate.
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@multicellgenome
Iñaki Ruiz-Trillo
3 years
Glad the lab has contributed to this book! @freejakoba made a thorough revision of clonal #multicellularity in #prokaryotes and #eukaryotes
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@wc_ratcliff
Will Ratcliff
3 years
Chapter 9 moves us into the domain of clonal multicellularity. Here, @freejakoba and @multicellgenome take on the Herculean task of examining the many independent origins of clonal multicellularity. This is our longest chapter (for good reason!). 19/32
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@multicellgenome
Iñaki Ruiz-Trillo
1 year
#animalorigins #agregation & #Capsaspora in @PNASNews congrats to @jp_gerdt & Núria, who both led the whole project, & rest of team! You rock! And the videos are amazing! #holozoans #diversity #evolution #filastereans
@jp_gerdt
J. P. Gerdt
1 year
Thrilled this is out! Fruit of a wonderful collaboration with Núria Ros-Rocher & @multicellgenome Chemical factors induce aggregative multicellularity in a close unicellular relative of animals | Proceedings of the National Academy of Sciences
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@multicellgenome
Iñaki Ruiz-Trillo
3 years
Aggregative #multicellularity has been described in a few taxa but it is present in all eukaryotic superclades. It seems like an uncommon type of multicellularity. Yes, it does. However, I bet it will be less and less uncommon the more we study different #protists along the tree.
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@multicellgenome
Iñaki Ruiz-Trillo
3 years
Yes! And one more PhD from the lab-the 11th!! Konstantina @Mitsikons ,as always, pure energy presenting her thesis!! with the best possible committee-thanks Puri @DEEMteam_Orsay , Naiara @naiara_re & Rosa @Rosamygale for being part of this! #phdlife #phd @IBE_Barcelona
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@SINGEK_ITN
SINGEK
3 years
Time to anounce another #PhD_SINGEK ! Congratulations @Mitsikons for a well deserved PhD, beautifully defended today and supervised by Iñaki Ruiz-Trillo @multicellgenome @IBE_Barcelona Best wishes for your new adventures!
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@multicellgenome
Iñaki Ruiz-Trillo
2 years
Animals and Fungi. So phylogenetically close & so different. Why is that? 4 novel holozoan #genomes & the fantastic work of Edu & col have nailed down the reasons for that. It is all about the past. Read the paper or... wait for Edu’s twitter thread to know more 😉 @nature
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@eduocapa
Edu Ocaña-Pallarès
2 years
Really glad to see this work finally published @Nature ! It's been a pleasure to work with all of you during these years @multicellgenome @sllsi @tweethinking @DLopez_Escardo @AliciaSArroyo @pjkeelinglab @jspathmanathan and others. Tweetorial coming soon!
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@multicellgenome
Iñaki Ruiz-Trillo
4 years
Marta @MRiutortUB was one of my two PhD supervisors. By her example I could see how you could put people first, papers second, and still be highly productive. A great example to me, an incredible mentor, and a wonderful friend and colleague. Thanks Marta!
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@multicellgenome
Iñaki Ruiz-Trillo
5 years
Very happy our building will host PlanktonPlanet from @TaraOcean_ . Great initiative @ICMCSIC to visualize the importace, diversity, and beauty of #plankton ! #research #oceans #nature #protists #scicomm #taraoceans
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Iñaki Ruiz-Trillo
3 years
Once more genomes of unicellular relatives of animals key to decipher #animalorigins . They seem to have relicts of metazoan chromosomal units. Interesting results! However, #Capsaspora is NOT an #ichthyosporean !🙏
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@multicellgenome
Iñaki Ruiz-Trillo
5 years
Wonderful day with the 10th PhD thesis of the lab. Great defense of Edu @eduocapa & some fun afterwards. Thanks committee members @JordiPaps @toni_gabaldon & Alex for wonderful debate! #phdlife #academialife #research #genomes #reticulateevolution @IBE_Barcelona
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@multicellgenome
Iñaki Ruiz-Trillo
2 years
After 14 yrs, I have ended my teaching assistant contract @GeneticsUB . Giving classes at the masters was the highlight of the year for me. One of the best moments. But, sometimes, you need to say no to the things you really, really enjoy. Thanks @GeneticsUB for all!
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@multicellgenome
Iñaki Ruiz-Trillo
4 months
New study reveals surprising twists in #dinoflagellate evolution! Photosynthesis lost 21 times, novel bacterially-derived histone-like proteins (HLPs) & several independent acquisitions of kleptoplastic species. Congrats @weeseamonsters & all authors! #Evolution #protists
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@weeseamonsters
Liz Cooney
4 months
Our big dinoflagellate paper is out! Highlights include transcriptomes for 39 heterotrophic species and new insights into character evolution of notable traits, like chromatin packaging proteins and rhodopsins. Enjoy!
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Iñaki Ruiz-Trillo
1 month
Once more, it seems the #archaeal ancestor of eukaryotes was more complex than previously thought! 😀 (reminds me of the unicellular ancestor of animals). In this occasion, it is the use of de novo protein structure modeling & sensitive sequence similarity algorithms that helped
@Ettema_lab
Thijs J. G. Ettema 🦠🔬🇳🇱🇸🇪🇪🇺
2 months
Our latest: Using de novo protein structure prediction and sensitive sequence searches we found many new eukaryotic signature proteins in Asgard archaea, suggesting the archaeal ancestor of eukaryotes was more complex than previously assumed. @koestlste
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@multicellgenome
Iñaki Ruiz-Trillo
6 years
An epithelium-like in an unicellular relative of animals? Maybe not an epithelium, but certainlya self-organized & polarized layer of cells is present in our beloved #icthyosporeans ! with @dudin_o @biorxivpreprint check it! #multicellularity #protists
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@multicellgenome
Iñaki Ruiz-Trillo
2 years
Our taxonomic composition assessment of #eukaryotes in Sanabria Lake now in @SciReports with @Mitsikons @DLopez_Escardo @AliciaSArroyo Meri & our good friends @proyectoagua & @balkalarre !😀Molecular novelty in some clades & 1st report of marine #ichthyosporeans in freshwater
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@multicellgenome
Iñaki Ruiz-Trillo
3 years
One of animal's closest relatives ( #Capsaspora ) creates temporal multicellular structures by cell aggregation. What triggers them, how are they made, and whether they could have had any role in animal origins are questions that we aim to resolve. #animalorigins
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@multicellgenome
Iñaki Ruiz-Trillo
3 years
Txikisporea philomaios now officially published. A potential new #filasterean species. Two of the authors have #basque names, so no wonder we used "Txiki" to design its small size. Lead by Ander & @endomyxan with @Mitsikons @freejakoba et al #protists
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@multicellgenome
Iñaki Ruiz-Trillo
1 year
We are absolutely delighted to welcome Jennah ( @Jennah_E_D ) as she joins our lab! With a postdoctoral grant from @Vetenskapsradet , she will delve into the captivating realm of #microbial interactions and their impact on the origin of animals. Exciting times ahead! #AnimalOrigins
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@multicellgenome
Iñaki Ruiz-Trillo
3 years
One of my dreams was that one day I will be able to work close to either Nicole @A_Nicole_King or Dan @balkalarre from @Choano_Lab and learn from them. The day has arrived! Dan's new office is just besides mine at @IBE_Barcelona !! Nicole, wouldn't you like to join the party? 🙏😉
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@multicellgenome
Iñaki Ruiz-Trillo
5 months
Just 3 weeks away from @PSuarezAra 's PhD defense! 🎉 The thesis, featuring an incredible #ichthyosporean image, is as stunning visually as it is rich in science. Thrilled to celebrate another milestone in #ichthyosporeans & #corallochytreans research. #multicellularity
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Iñaki Ruiz-Trillo
4 months
Interested in exploring evolution, cell biology, & ecology of #protists in a Mediterranean setting? 🌊🔬 Barcelona hosts a vibrant cluster of interconnected protist labs! 🌿🧪 Meet the teams at @IBE_Barcelona : @balkalarre , @delCampoLab , and ours; plus @ramalok & @RMassanaM at
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@MSCActions
Marie Skłodowska-Curie Actions
6 months
Heads up! The #MSCA Postdoctoral Fellowships 2024 call opens in April. 🔍 Start your journey early by exploring potential host organisations now and gear up to craft the perfect proposal! 🌟 🎓🔬 More info and opportunities this way ➡️
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Iñaki Ruiz-Trillo
3 months
Very good news! Cédric Berney joins the hunt for the Magnificent8 relatives of animals! Cédric will be our 18S rDNA expert, as he knows by heart the 18S of each of the 8 missing lineages. Wellcome to the lab, Cédric! #multicellularity #magnificent8 #animalorigins @IBE_Barcelona
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@multicellgenome
Iñaki Ruiz-Trillo
5 months
Are #choanoflagellates , #filastereans , #ichthyosporeans & #corallochytreans truly the best models for exploring animal origins? While these lineages have been so far pivotal to address the origin of animals (and they surely will continue to be!!), eDNA has revealed that there
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Iñaki Ruiz-Trillo
3 months
And here's Abeoforma whisleri, the second #ichthyosporean we have equipped with genetic tools! This amazing organism shares many genes with animals & has fascinating cell biology, offering insights into animal evolution. 🧬🔬 #multicellularity
@multicellgenome
Iñaki Ruiz-Trillo
3 months
🔬🦠We are unlocking the secrets of animal origins! Meet Creolimax fragrantissima, a stunning single-celled organism closely related to animals. This #ichthyosporean shares fascinating genes with animals & is one of the few that offers genetic tools for research. Want to study
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Iñaki Ruiz-Trillo
4 years
Very sad. Huge loss. Jose Luis not only taught me (and people from my lab) many things, but he made me laugh almost all the time, and he influenced my research and my science in many ways with his enthusiasm. Great, amazing person. Our thoughts are with his family.
@Dmc2Cabd
DMC2 CABD
4 years
With all our sadness, today we lost our colleague & friend! Jose Luis ( @jlgomska ) was one of the pioneer researchers of the CABD when it was only a dream. His energy and perseverance made this dream real. He is gone well before his time....
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Iñaki Ruiz-Trillo
3 years
My friend & planarian-researcher Emili Saló from @GeneticsUB already told me 20 yrs ago: "If you listen to your children and get a dog, you need to know that YOU will be the one walking it EVERY morning". As usual, he was right....😂
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Iñaki Ruiz-Trillo
3 years
Only a taxon-wide functional platform will allow us to address animal origins. Yes, taxon-wide! That was our mantra @Elenacleomina @SebasNajle For 15 years! Now, the mantra is real. Now the platform is here! Now, season 3 begins! 1/3
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Iñaki Ruiz-Trillo
3 months
Our mission to find the 'Magnificent 8' continues! Eight elusive lineages closely related to animals but yet to be discovered. eDNA data suggests the Mediterranean coast harbors some of those animal relatives. So, this week Rubén, with the help of Maria from @RJBOTANICO went to
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Iñaki Ruiz-Trillo
4 years
After almost 6 yrs, Sebas @SebasNajle is leaving the lab. We all learned a lot from you, Sebas! It has been a pleasure to have you here! Good luck in the new adventure in @ArnauSebe 's lab! @IBE_Barcelona #academiclife #postdoclife #research #protists
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Iñaki Ruiz-Trillo
3 years
We didn't sequence more genomes for fun. I mean, it is fun!, but we did it to get the most accurate possible evolutionary reconstructions. Here a larger taxon sampling redefines origin & evolution of Rel/NF-κB. #animalorigins #taxonsampling @freejakoba @SebasNajle @IBE_Barcelona
@ISEPprotists
ISEP
3 years
New #ISEPpapers ! Rel/NF-κB transcription factors emerged at the onset of #opisthokonts : Michelle Leger et al. #protists by @freejakoba @multicellgenome
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Iñaki Ruiz-Trillo
7 months
Groundbreaking study by @andrewjroger , Yana, Alastair & co. on 'Meteora sporadica'! They unravel a stunning eukaryotic lineage that reshapes our understanding of #protist diversity. A reminder of the unexpected diversity in #eukaryotic life! congrats! #evolution #protists
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@andrewjroger
Andrew J. Roger
7 months
Introducting Meteora sporadica, a most weird and wonderful protist:
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Iñaki Ruiz-Trillo
2 months
Wonderful news! The great Guifré @guifftc joins the lab to lead our participation in a project to reconstruct the unicellular ancestor of animals, in collaboration with @dirk_fasshauer @cdessimoz @pedrobeltrao . Welcome back, Guifré! @IBE_Barcelona #protists
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Iñaki Ruiz-Trillo
4 months
Not only bacteria, also red algae, through a polysaccharide seems to induce multicellular development in the choanoflagellate Salpingoeca rosetta. Nice to see the diversity of biochemical interactions that produce multicellular behaviour on #choanos . Congrats @dsboothacosta &
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Iñaki Ruiz-Trillo
4 years
With this, the family picture is completed: transfection is now possible in all major unicellular lineages closely related to animals!: #choanoflagellates , #filastereans #ichthyosporeans & #corallochytreans . Time to enjoy these tools!! #research #dreamcometrue #animalorigins
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@xgraubove
Xavier Grau-Bové🌾
4 years
Stable transformation of the enigmatic holozoan Corallochytrium limacisporum — finally out in the open! From Aleksandra Kożyczkowska, Sebastián Najle, @eduocapa , Cristina Aresté, @multicellgenome & @Elenacleomina .
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Iñaki Ruiz-Trillo
5 years
Today is my last day as a member of the diversity committee @IBE_Barcelona with @Elenacleomina It has been 5 yrs in which I learnt a lot about #diversity #womeninscience #womeninstem & I realized how much needs to be done! Thanks @Rosamygale for accepting to follow up! @the_prbb
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Iñaki Ruiz-Trillo
1 month
Exciting new research that suggest the archaeal-eukaryotic ancestor had the capacity for aerobic respiration, maybe providing energetic advantages during early eukaryogenesis! Nice to see so many new Asgardarchaeota metagenome-assembled genomes (MAGs). Congrats to the
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@archaeal
Brett Baker
2 months
After many years of work we present a preprint that doubles the numbers of Asgard genomes, revealing lots of new insights into their metabolism. Notably, lineages closely related to eukaryotes are capable of aerobic respiration! @katy_appler @val_deanda
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@multicellgenome
Iñaki Ruiz-Trillo
2 years
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@multicellgenome
Iñaki Ruiz-Trillo
4 years
yeah! a new #protist closely related to animals! Great work by @pjkeelinglab @CurrentBiology A pity its phylogenetic position is unclear-but no worries, already running our own trees 😉
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@multicellgenome
Iñaki Ruiz-Trillo
5 years
Nicole King @Choano_Lab closes the #choanomeeting19 with a call for collaboration, not competition. My impression is that is that we have & we need to keep it this way. Integrating other unicell relatives of animals into the community will surely strenghten it! #collaboration
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@multicellgenome
Iñaki Ruiz-Trillo
5 months
What a fantastic day! A big thank you to @PSuarezAra for an incredible 4 years of PhD research pursuing the establishment of genetic tools in #ichthyosporeans & #corallochytreans ! Thanks to @SebasNajle for co-supervising with such knowledge and enthusiasm. Thanks Núria Ros i
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@multicellgenome
Iñaki Ruiz-Trillo
5 years
“We don’t really know if it’s an animal, if it’s a fungus, if it’s in between,” What??? it is a #protist !! And nice and interesting as most protists. Anyway, happy Physarum made it to a zoo! 😏
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Iñaki Ruiz-Trillo
5 months
Diving into the microscopic world in the book 'Hallo Plankton' 🌊🔬! happy to have been a small part of this journey alongside illustrator Kristina Heldmann together with @Guse_Lab & others. Kristina has made an amazing work to show the beauty of plankton through art!
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@multicellgenome
Iñaki Ruiz-Trillo
6 years
Dan Richter @balkalarre got a Marie Curie #MSCA fellowship with his project on understanding the ecology of the oceans by tackling the most abundant #protists . Very excited about this new project! @MSCActions @IBE_Barcelona #research #biology #ecology #science
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@multicellgenome
Iñaki Ruiz-Trillo
3 years
Our aim is to break the huge knowledge asymmetry that has existed between animals and their unicellular relatives for far too long. We have done a lot, specially at the level of genomes. But, we can do more, and we’re committed to doing more! #multicellularity #animalorigins
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@multicellgenome
Iñaki Ruiz-Trillo
1 year
Get ready for a revolutionary year in #Ichthyosporea with @Elenacleomina ! Optimized genome assemblies, new cell biology features, and for the first time ever, we will expose #icthyos to unique environmental conditions!! @IBE_Barcelona #Protists #AnimalOrigin #Ichthyosporeans
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@multicellgenome
Iñaki Ruiz-Trillo
5 years
Once more, proteins & protein domains previously thought to be animal-specific are present in their unicellular relatives. In this case, proteins involved in cell-cell contact formation such as ERM and merlin; by Shabardina & others @OfficialSMBE #protists
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@multicellgenome
Iñaki Ruiz-Trillo
5 years
Published our analysis of global molecular diversity of #Platyhelminthes with @Mitsikons . A lot of unknown diversity, potential novel clades & the importance of fresh-water environments for new species @RSocPublishing #metabarcoding #diversity #animals
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@multicellgenome
Iñaki Ruiz-Trillo
6 years
Multicellularity 2.1 billion years ago? New fossils from Gabon claimed to be from a #multicellular or syncytial organisms. They suggest similarity to slime molds. If confirmed, that's amazing! via @PNASNews #multicellularity #protists #fossils #slimemolds
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@multicellgenome
Iñaki Ruiz-Trillo
3 years
Three decisions will be crucial when starting your lab: 1) what to investigate (line of research), 2) where (institution/university/city/country), & 3) with who(the team). I would argue that 2 & 3 are the more important ones. A bad decision in those can really affect your career.
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Iñaki Ruiz-Trillo
6 years
Núria defended her PhD thesis today. Great work on Capsaspora, to understand animal origins. This is the 7th PhD thesis of the lab!! Thanks Cristina Grande, @Elenacleomina & @Pawel_Burkhardt for being part of the committee #phdlife #team #phdstudent #science #protists
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Iñaki Ruiz-Trillo
5 months
The #nitroplast , a potential new organelle resulting from a #symbiosis between a nitrogen-fixing bacterium and an alga. The result is an adaptation of the microalgae Braarudosphaera bigelowii to nitrogen-limited waters. As @RMassanaM mentions in his nice comment
@ScienceMagazine
Science Magazine
5 months
A nitrogen-fixing organelle, or “nitroplast,” has been identified in a marine alga. This discovery sheds light on the evolutionary transition from endosymbiont to organelle. Learn more this week in Science:
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Iñaki Ruiz-Trillo
1 month
Delve into the fascinating world of #Ichthyosporea in our review @SpringerNature @CommsBio with @victoriashabard @Jennah_E_D @PSuarezAra @merimonas et al. Thrilled to have collaborated with pioneers in Ichthyosporea like Wyth & Hiroshi, who laid the groundwork in isolating
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@multicellgenome
Iñaki Ruiz-Trillo
5 months
New article show siphonophores exhibit a broad range of nuclear genome sizes suggesting significant genetic diversity within this group. In contrast, mitochondrial gene order seems conserved among #siphonophores ! I wonder what evolutionary pressures led to their variation in
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@evol_genomics
Evolutionary Genomics
5 months
Giants among Cnidaria: large nuclear genomes and rearranged mitochondrial genomes in siphonophores @GenomeBiolEvol
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Iñaki Ruiz-Trillo
3 years
"A man entranced by an amoeba". I have never been described this way before, but indeed! I would say "A man entranced by #protists in general". Enjoying every page of Rebel Cell by @Kat_Arney . A great revision of what is known of #cancer & #multicellularity #Capsaspora #scicomm
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@multicellgenome
Iñaki Ruiz-Trillo
3 months
Amazing cover featuring a fascinating cell behavior of a ciliate! 🦠✨ Times are changing! These discoveries and these poorly-known organisms, once mostly confined to specialized journals, are now hitting the mainstream. Exciting times for #protist research! Congrats @PrakashLab
@ScienceMagazine
Science Magazine
3 months
The tiny predator Lacrymaria olor owes its shape-shifting ability to an “origami-like” cellular architecture, a new Science study finds. The results offer a glimpse into geometrical control of behavior in single cells. Learn more in this week's issue:
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Iñaki Ruiz-Trillo
5 years
We had Alicia's PhD defense this morning. Very happy about this PhD, the 8th of the lab and the first one in #biodiversity & #metabarcoding ! Thanks @ramalok Philippe & @MRiutortUB for being part of the PhD committee, & thanks Alicia for all these years! #research #phdlife #PhD
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@multicellgenome
Iñaki Ruiz-Trillo
1 year
A great example of the importance of taxon sampling to understand evolutionary transitions & the relevance of the environment & the adaptations of single-cell organisms to the posterior acquisition of #multicellularity . Great work by @CKCornwallis @CoelhoSvensson @krengefors etal
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@NatureEcoEvo
NatureEcoEvo
1 year
Single-cell adaptations shape evolutionary transitions to multicellularity in green algae
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@multicellgenome
Iñaki Ruiz-Trillo
6 years
Congrats to Xavier Grau-Bové @xgraubove for obtaining University of Barcelona PhD extraordinadry prize, as one of the best PhDs presented in 2016-2017 academic year. Congrats Xavi! @IBE_Barcelona @GeneticsUB @IRBioUB #proud #team #science #ciencia #research #phdlife #tesis
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Iñaki Ruiz-Trillo
2 years
More on animal origins! p38 kinase, a key element of the cellular stress response in animals, was already present in the common ancestor of animals & fungi. Great collaboration with @jjsanzezquerro @CuendaAna @CNB_CSIC @IBE_Barcelona with Vika, Ester, Pedro & @GonzolinBS
@jjsanzezquerro
Juanjo Sanz Ezquerro
2 years
Out now in #OpenBiology @RSocPublishing 👉Evolutionary analysis of p38MAPK Great collaboration with Vika Shabardina and Iñaki Ruiz-Trillo @multicellgenome @IBE_Barcelona @CuendaAna @CNB_CSIC 👁️p38 in unicellular relatives of animals, new p38γ/δ, aa changes
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Iñaki Ruiz-Trillo
6 years
#Choanoflagellates mutants that aggregate promiscuously into amorphous clumps. The genes involved are glycosyltranferases. Maybe capacity to aggregate is not that unusual among unicell relatives of animals? Great paper by @Choano_Lab in @elife #research
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Iñaki Ruiz-Trillo
3 years
Another example of gene loss in #metazoans . In this case, Wnt genes in #tardigrades . Could that be related to their simplified development and miniaturization? The authors speculate it may. Work by @chico_snake et al. @BioMedCentral #evolution #geneloss
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@BMC_series
BMC Series
3 years
In #BMCEcolEvol , researchers @UofNorthFlorid investigate the body plan evolution of tardigrades and find that loss of Wnt genes may be related to their simplified development, anatomy and miniaturization. To learn more, visit <>. @chico_snake
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Iñaki Ruiz-Trillo
5 months
Bidding a heartfelt farewell to our dear @koryu_kin after an incredible 4 years together. 🌟 Your contributions to #holozoans research and our lab's spirit have been invaluable. Wishing you all the success and groundbreaking discoveries ahead in Japan! 🥰🥰🥰 #team #academialife
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Iñaki Ruiz-Trillo
7 months
Amazing work by @MaaikeBier @IkerIrisarri @Jan_de_Vries & others on Klebsormidiophyceae! Unveiling 24 new transcriptomes, their phylogenomic analysis reveals the ancestor of Phragmoplastophyta & #Klebsormidiophyceae was #multicellular ! @CurrentBiology
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Iñaki Ruiz-Trillo
2 years
"It turns out that the length of the reads (from MinION) over-competes the randomly generated sequencing errors and brings accurate phylogenetic information." This is music to my ears.... #longread #biodiversity #metabarcoding Great work!
@SandinMM
Miguel Méndez Sandín @[email protected]
2 years
Is #MinION long-read #metabarcoding suitable for exploring microbial environmental diversity? Yes, it is! We compared Sanger, Illumina and @nanopore to explore #rDNA intragenomic variability in #Radiolaria W/ @fabrice_sbr & Sarah Romac @phytopk @SBRoscoff
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Iñaki Ruiz-Trillo
6 months
So grateful for the phenomenal women in our lab. Their leadership & generosity pave the way for a more inclusive science & they make our lab better. A pity their path remains unfairly steep. #WomenInSTEM #InternationalWomensDay
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@multicellgenome
Iñaki Ruiz-Trillo
5 years
Ready to go sampling to a cave used as an analog to Mars by @AstrolandAgency with Antonio @proyectoagua Carmen, Tir @DhondyTir A mission with biological goals, to search for #protists #biodiversity @IBE_Barcelona @BBCTravelShow
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Iñaki Ruiz-Trillo
3 months
🔬🦠☢️We love crazy ideas!.... specially if potentially relevant to address the origins of animals. Check out our new experimental evolution project with one of our beloved #ichthyosporean , a close unicellular relative of animals; collaborating with @labsubcanfranc .
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Iñaki Ruiz-Trillo
2 years
Days like this compensates for others kinds of days. Nice to see Aleksandra defend so well her PhD!! 💪 So grateful for having done this path with @Elenacleomina 🙏 Thankful for committee members Cristina Grande, Drahomíra Faktorová & @balkalarre #phdlife #PhDone #animalorigins
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Iñaki Ruiz-Trillo
4 months
Such a nice day yesterday! Núria, a previous PhD student, came back to the Institute to give an @IBE_Barcelona seminar and she got a rockstar welcome! It wasn’t just for her impressive science on #choanoflagellates (now at @thibaut_brunet 's lab) but also for the lasting positive
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