What trait confers the greatest evolutionary advantage to a species? Being useful to humans

@owl_posting I think this sort of makes sense, but it’s not just about the number of people dying but also quality of life. Even in the most developed nations, HIV positive individuals have stay on HAART. Perhaps lencapavir changes that, but it’s still not a cure

@JohnStreicher1 For someone of his qualifications, I am taken aback by how differing his opinions are to so many others in the field

@kenbwork It is a beautiful book, I’ve read it page to page 3 times now

RT @SamuelBHume: This is like AlphaFold, but for protein localisation rather than folding It's a deep learning model that predicts a prote…

@pdhsu It is art, not only in the creativity of methodology and question asked, but also the physical system your work uncovers (new protein, transduction system, expression levels etc.). I think that’s where the wonder is, something that invokes emotion

@20th_Centurygal Pink Floyd, Rush, Ofege

RT @SamuelBHume: This is fascinating Some proteins 'phase separate' - they form droplets, like oil in water, that concentrate them in cert…

@MitoPsychoBio @drmichaellevin Placebo is interesting because you see “action” occurring without that intermediate phase. It occurs autonomously without the subject making a conscious effort?

RT @plasmidsaurus: The only thing cooler than protein folding? Protein folding into a dinosaur. 🦕

@plasmidsaurus Oh wow, that’s actually very good

RT @JExpMed: Tan, Dong et al. @Westlake_Uni show that Th1 cells convert into T-bet+ pTreg cells in response to TGF-β signaling in the TME.…

Or is life only possible in conditions which is permissive to the formation/stability of these elemental structures.

Finding the balance between: enjoy the science and worry about your future in science, is tough

Hypoxia inducible promoter which causes transcription of oncolytic viruses in a carrier cell when it reaches the deepest point of a tumor, avoiding off target effects. Could be used for drug delivery, novel target display, or direct virus mediated tumor death?

@ATinyGreenCell Oooo nice one!

@MitoPsychoBio ATP required for the secretory vesicles + for the formation of the synapse. Are we counting what went into making the caspases and granzyme?

@1leone @MitoPsychoBio Probably granzyme and caspases. These initiate apoptosis in the tumor cell and are known “killing” mechanisms of cytotoxic cells