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Michael Mejia
@mikemejiamd
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Chair, Department of Radiation Oncology University of Santo Tomas Hospital. Head and Neck Unit BCI Tweets are my own.
Manila City, National Capital
Joined May 2010
RT @EChrisDee: The @USTFMSofficial and #Philippine #Dental Association #oral #oncology seminar series 🇵🇭 Dr @MikeMejiaMD's introduction to…
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Fantastic summary of MDT trials and directions in OMBC! Key question to our #bcsm #radonc #sbrt folks: DOES an oligometastatic state exist in breast cancer? @luisajacomina @IBCradiation @SFShaitelmanMD @CJTsaiMDPhD @drdavidpalma
🧵 SBRT in Oligometastatic Breast Cancer: What does the evidence show? A summary of key studies and their impact on survival. Let’s dive in! 👇 1/ What is Oligometastatic Breast Cancer (OMBC)? OMBC is an intermediate state between localized and widespread metastatic disease, characterized by limited metastases (typically ≤5). It’s a promising target for local therapies like SBRT (Stereotactic Body Radiotherapy).
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Brilliant explanations below 👇
My brilliant med student asked me to explain correlation, causation, confounding &collider bias. I used the following ex… so sharing here in case anyone finds it helpful! PS -I have learned much from @dnunan79 @Catalogofbias - a great resource for EBM. hopefully he approves😅
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RT @DBelardoMD: My brilliant med student asked me to explain correlation, causation, confounding &collider bias. I used the following ex… s…
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In today’s @QuadShotNews and now on @IJROBP as pre-proof‼️ Excited to share our study on palliative RT for breast cancer @MDAndersonNews 💖RT is effective in palliating symptoms from LABC 💕More RT isn’t always better (or necessary?) 💘QOL is 🔑
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Kudos to @NRGonc HN team led by @Qle_stanford and @sueyom for publishing HN004. Need to identify better treatment options for curable cisplatin ineligible #hncsm patients
Final results of NRG HN004 coming out in Lancet Oncology, press release to follow, RT/cetux results look relatively strong for cisplatin ineligible HNSCC
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Need a more robust discussion to redefine patient selection for MDT as this is now a moving target. @CJTsaiMDPhD @_ShankarSiva @DrMLChua @VedangMurthy @drkevin_chua_lm
"Oligo"-no more! 🇨🇦ARREST phase I out now @IJROBP - @sueyom ➡️SABR to median=16 "poly"metastases in patients who had already exhausted multiple lines of systemic therapy ➡️4x dose levels (up to 6Gyx5). ➡️No safety signals, QoL maintained. Congrats! 👏👏
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@DrMLChua @ASCO @lynn_schuchter @ASCOPres @jrgralow @davisa20 @lillian_siu @herbloong @DrRoselleDG @DiahMartina2 @drkiwikate Congratulations buddy
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Excellent work by my colleague @WarrenBacorro from @UST1611official and the GEC ESTRO on HN #radonc #brachytherapy
Just published online! GEC-ESTRO recommendations for #headandneckcancer #brachytherapy (interventional #radiotherapy): 2nd update with focus on HDR and PDR. 👉 Read the article:
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Cisplatin still king in fit patients Important to properly select patients who are not cisplatin candidates But does avelumab really improve outcomes? (p=0.059) Important work nonetheless at #ESMO2024 in #hncsm Glad to see #radonc papers in #medonc meetings
Congrats to my friend @YG_TAO & GORTEC for this huge trial of IO in LA HNSCC Avelumab-cetuximab inferior to cisplatin CRT in fit patients but superior to cetuximab-RT for PFS in cisplatin ineligible population. #ESMO2024
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Easy to understand talk with excellent synthesis. Kudos @VedangMurthy from @TataMemorial
@luisajacomina
@EChrisDee
@MichelleEalaMD
@DrMLChua
@drkevin_chua_lm
#ESTROAsia24
@VedangMurthy giving an elegant overview as always on role of pelvic node irradiation in #ProstateCancer Amazing how many trials @TataMemorial run for #GUCancers
@piet_ost @TylerSbrt @AmarUKishan @mikemejiamd @scserendipity1 @aleberlin2 @alison_tree @_ShankarSiva @a_dalpra
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Stoked to see this published and to have someone like @luisajacomina on the PH #radonc scene
Our #radonc opinion on this month’s interesting Gray Zone case @IJROBP ⬇️ Thank you @AmyMorenoMD for the guidance and opportunity! 🌟🫶🏻 @MDAndersonNews
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Expanding #hncsm #radonc #cancer horizons with colleagues from across the archipelago and the Pacific
Exciting discussions with @USTFMSofficial and @MSKCancerCenter multidisciplinary teams on how to expand access to #oral #oncology #cancer #care in the #Philippines 🇵🇭 🙏 Drs @MikeMejiaMD, @LuisaJacomina, Cherry Estilo, Gelo Militante, Ian Fernando, and Sandy Uy
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@DrMLChua @DavidSherMD Absolutely agree 💯 Different sequences in MRI in NPC is underutilized and under appreciated, hence full potential of the examination isn’t realized.
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🚨📸HN Rad Oncs - would you change your ADJ RT practice for INT RISK (close margin, < 1mm ENE, 2-4LN, +PNI/LVSI) HPV+OPC after ECOG 3311 long-term results after #ASCO24. Assuming no other de-escalation protocol available? (Had to redo the vote due to poor wording/choices 😃) @DrMLChua @drdavidpalma @DavidSherMD @KaramLab @JamesBatesMD @ChristinaChapMD @henson_md @ScottBratman @DanielMaMD @seanmmcbride @xrtGenomics @yaoyu_md @LChen_MD @RobertFerrisMD @HSkinnerMDPhD
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I found this VGR by @Mat_Guc and colleagues from Zurich extremely informative and insightful. I highly encourage my #radonc colleagues to attend
Virtual Grand Rounds in Radiation Oncology Potentially Radiation-Oncology changing clinical trials from ASCO Annual Meeting 2024 Critical appraisal from Radiation Oncologists for Radiation Oncologists Wednesday July 3rd 5:00 – 5:30 p.m.
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@DavidSherMD @yuanjamesrao As in everything in life, TIMING IS KEY. IO may be a game changer but it is apparent that we need to rethink treatment strategies like timing and volumes.
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@DrMLChua @DavidSherMD @seanmmcbride Agree. While it seems that the Ph2 30-40Gy data shows promise, I think patient selection on the basis of biology is the cornerstone and cannot just put all patients (no matter how “homogeneous” they initially seem) in a single basket. The worst toxicity of RT is local recurrence
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@EChrisDee @fredtingmd @NiuSanford @way2spy @MichelleEalaMD Misconceptions go beyond AEs I think. A lot of hesitations seem to stem from gossip. 😂
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@fredtingmd @NiuSanford @way2spy @EChrisDee @MichelleEalaMD Multifaceted issues including preconceived misconceptions on both ends. Need a holistic assessment
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