Prof. Lee Cronin
@leecronin
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CEO & Founder, Chemify. Regius Professor, Scientist & Inventor. Fascinated & in a state of confusion & optimism. Trying to digitize chemistry & make alien life.
Somewhere in the chemiverse
Joined May 2009
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I don't think ChatGPT is going to be a chemist anytime soon...
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Nothing is more important than finding out how the universe works. Nothing.
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We invented the Chemputer to make chemistry universal with respect to digital programmability. This is why
#chemputation
should have significant reach across science & technology.
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My oddest moment being an academic recently was when a student told me he could not do a PhD with me because my IQ was ‘too low’. I asked them how they knew. They replied because ‘I see it in your eyes.’
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Artificial intelligence should be renamed applied maths.
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Today I made an anti cancer drug live on stage during a talk using my programming language & mini robot capable of
#chemputation
.
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Lets replace all references in manuscripts with DOIs & eliminate the tyranny of reference formatting.
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For the last decade people have been telling me the digitization of chemistry was impossible. They said it was too complicated, sensitive and expensive. Our chemical programming langauge runs on cheap hardware and can make any molecule or material.
#chemputation
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A quick thread on our
@Nature
paper on Assembly Theory. 1/10 Assembly theory provides a new framework to understand selection and evolution that integrates physics and biology. It redefines objects not as particles but by their formation histories.
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Today I’m dreaming about how the implementation of universal chemical assembler, a Turing complete chemist aka the Chemputer, can make any physically allowed molecule or material.
#chemputation
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I made a new Eisenhower diagram that is fit for purpose.
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I’m of doing a zoomposium on Assembly Theory this Friday 13th Oct at 5 PM BST for 60 mins. Open to all. Zoom link here: Please like if coming & retweet to spread the word.
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I’m an academic anarchist. I don’t conform. I have my own ideas & thoughts. I value creativity. Stop making me feeling guilty for being an individual because I don’t fit in your small little perfect box of boring.
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Networks of interacting balls undergoing physical selection.
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The actual anti cancer drug, Lomustine, being made in our portable chemputation platform in Ojai Valley California - everything was shipped from Glasgow for this demo!!
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I can announce that our universal chemical programming language, XDL, which can be learned by any chemist within 1 hour & can easily run almost ANY chemistry robot will be given away to everyone for free (academic or commercial) no strings. Official announcement soon!
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When I was 9 I was put in the special needs class as I was found to be disruptive (with ADHD & on the spectrum). Even worse I was found to have below average intelligence. I was so sad I wasn’t smart, & I still feel ashamed even to this day because I wanted to be a scientist.
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Saturday night in my workshop doing high voltage self-assembly.
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I think
@elonmusk
is wrong about the possibility of civil war in the UK but he has the right to an opinion. Those who say he should be silenced are creating the road to tyranny.
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Don’t give up. Whatever the distraction, be flexible on the route, but don’t ever sacrifice the vision. Vision makes the impossible possible. We drag it kicking & screaming from the future into the present. Don’t give up. I’m rooting for you.
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We invented Assembly Theory to explain & quantify selection & evolution. We believe this will have reach because it explains the universality of selection in the universe, how to make life in the lab, as well as help us find alien life forms.
#assemblytheory
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This paper not only presents a new theory for understanding life by exploring chemical space with assembly theory, it also shows how we can experimentally measure the complexity of molecules with no prior knowledge of the system (no need for AI / ML).
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Our Assembly Theory paper is just out in
@nature
A gerat collaboration with
@Sara_Imari
@ASU
and
@sfiscience
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We must not discriminate against young researchers who are starting out independent careers by scolding them for building a little on past work. If they go completely off piste they are then told it’s not feasible because of no data or track record! This is impossible to square.
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The conception of the broad class of programmable chemsitry sets known as the chemputer marks a jump to universality for synthetic chemistry comparable to that of the mechanical calculator for mathematics.
#computation
➡️
#chemputation
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Imagine you take someone’s work & you compress it into zip format. You then do this for countless other original work & add them to the zip file. You then query the zip file with a question & you sell the output as being yours. Can you now understand why this is unethical?
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As promised by
@stuartcantrill
here is a video of me doing baby shark. If nothing else I can use it to say happy new year, cause we are going to need a sense of humor next...
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What is the point of these questions? Why are they relevant to my grant application?
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Can we do programmable computations in a chemical media where the chemistry does the computation? YES! This was an epic journey. Finally published:
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My next lockdown lecture will be on Thursday 10th Dec at 14:30 GMT and is called: 'The Invention of Digital Chemistry. What? Why? How?' Open to all! Please retweet.
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In chemistry & materials science AI dream without AI action is just an electric-dream. This is why chemistry needs
#chemputation
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If an AI becomes sentient before I do I’ll be really pissed off.
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I think we should spend $10T on finding / making aliens because that will yield more benefits than spending it on chips for AI to just machine learn what we already know.
@sama
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Karl Popper’s work explains why LLMs cannot generate new explantory knowledge.
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Universities should promote intellectual disobedience.
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Sometimes I find writing so hard. I literally feel I have nothing useful or insightful to say. I can see it, but I can’t articulate it precisely enough to make sense. My ideas, such as they are, seem to be visually locked & I lack the ability to translate them into words.
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My prediction. In an age of lazy humans & ChatGPT authentic writing & ideas will become the real gold.
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The human brain is already a super intelligence as it is capable of universality. Any super intelligent AGI will not be more capable as you can’t get more universal than universal.
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Today I’m giving a seminar on assembly theory & the evolution of the universe …
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Well done for
@CroninLab
- an important step to reducing manual lab work for synthetic chemists. Robots can now, in principle, reproduce the literature with little manual work - truly dial a molecule!
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Congrats to Hsin (Cindy) Wang for passing her viva today! The 86th PhD student from
@CroninLab
!!
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I fear that climate change guilt could be used to actively suppresses our ability to generate new knowledge that might itself reverse climate change.
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The anti nuclear movement has done more to damage the climate than the fossil fuels industry.
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I will die on the hill of critical thinking above all else. Cancel culture or not. The only way we make progress is by critical thought & open discussions. Fear of critical thinking will kill humanity quicker than AI / nuclear / climate change etc etc.
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Quantum chemputation extends chemputation in a similar way to quantum computation on a Turing machine but with regard to chemical transformations.
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So I flew a drone over a volcano whilst it was erupting today!
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The is a special place in hell for people who produce electronic forms that require written signatures to validate the form.
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I’m giving a workshop on grant writing tomorrow but today my 4th grant in a row was rejected including two rejections from the ERC in two weeks & one not even getting through stage 1. But some advice is important - don’t give up & everyone gets rejected. Everyone. Keep trying.
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Introducing C3-PU: The Compact Chemputing Chemical Processing Unit
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The entropy in academia is at an all time high such that there is literally no time for meaningful research. It is time for a bonfire of all the rules & regulations & fake jobs supporting them.
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Talking about building stuff is easy but actually building real stuff is exponentially hard, requires focus, vision, & courage. I’m trying to build stuff… …that chemputes…
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Assembly theory is going to change things. Since Darwin, we have tried to understand how the countless forms of life can evolve in a universe with fixed laws. The laws of physics are connected to life, evolution, and human culture, but they can't predict their emergence. Assembly
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I find it odd that when I do science across boundaries people tell me to stay in my lane & suggest I’m stupid. I know I’m limited, but should that mean I’m not allowed to even try & if I do I get publicly belittled? ‘try not to be like Lee’.
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The development of a programming language for chemistry that allows the sharing of reproducible synthetic recipes has long been a dream. Now with
@procrastiprof
it has come true!
#chemputation
& the paper here
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Fuck it. I’m just going to build a time machine in my workshop tonight.
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Interested in digital chemistry, robotics & chemputation? Want to access parts of chemical space you can only imagine but not physically, reliably or safely get to? Positions opening very soon. Join us!
#chemify
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How can the universe be computational at its base when everything in the universe is not computable? I guess I’m being stupid…
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Don’t mix up long hours & achieving excellence in science. Commitment leads to excellence & that does not mean hours worked. This can mean focus, determination, resilience & tenacity, but these things don’t demand long hours. You can achieve mediocrity with a 80 hr work week also
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Digital Chemistry was born at the University of Glasgow almost a decade ago. Take a look at the first & only purpose built digital chemistry facility in the world based here in Glasgow!
@CroninLab
@UofGlasgow
@UofGChem
@UofGARC
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Freedom to think critically, of speech, & to think & say unpopular things without punishment is the only way humanity improve. This should not be controversial because unless errors are made, there can be no error correction.
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The concept of AGI is wrong headed. Intelligence is rooted in biological, cultural, & technological evolution. It cannot exist independently.
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A day in the life of digital chemistry & chemputation. This is the future for chemistry!
@chemifyX
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I’m no longer a materialist. I’m now a temporalist. Same physical reality, just understanding time is more fundamental than space.
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I’m a science introvert & I think the only way to think well is to think critically, deep, & different. This does not get you superficial friends & it’s lonely. Funny thing is that science really needs contrarians or nothing radical will happen. Ever.
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We need to declare war on all institutions & ideas that protect mediocrity.
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How exactly is the AGI going to kill us? Any ideas? The nonsense being shared right now displays a staggering lack of understanding.
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Had a little chat about aliens with
@Sara_Imari
&
@lexfridman
Both amazing people. I was happy to tag along.
Here's my 4 hour conversation with Sara Walker (
@Sara_Imari
) and Lee Cronin (
@leecronin
) all about alien life out there in the universe. Sara is an astrobiologist and theoretical physicist. Lee is a chemist. Both are brilliant, bold, hilarious, and fun.
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Political correctness & cancel culture have reduce the dimensionality of people to being good or bad, left or right, my friend or my enemy. This is bad. It’s vital to argue the idea not the person. This approach is not had & it’s vital for the future of humanity.
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This is how easy it is to build a modular chemputer that can be programmed to do organic synthesis as described here:
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I will die on the hill of academic freedom & freedom of speech. I won’t stop being critical & honest whatever the cost.
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‘Just because you are offended, it does not mean it was offensive’. People urgently need to learn to think critically & do away with their outrage. Outrage & offense is the biggest barrier to mental growth & critical thinking.
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I’m pretty annoyed that everyone is portraying Italy as having failed against COVID-19. That is simply not true. UK, US & many other places in the world & going to face the reality soon. Time to stand together.
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What is going with the publishers? Why is this relevant?
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I’m a scientist, an experimentalist, a theorist, & a philosopher. I explore chemistry, computation, physics, biology, & engineering. I don’t see why I need to choose when the problem chooses for me..
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Science is about being wrong. The idea is to get progressively less wrong over time.
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