In 1921, 4 medical visionaries began a small clinic in Cleveland, Ohio. 100 years and countless medical breakthroughs later, the Cleveland Clinic is a global...

For the 30th year in a row, U.S. News has recognized Cleveland Clinic’s legacy of cardiovascular excellence, naming it the No.1 heart hospital.

At high-volume centers with meticulous preoperative planning, the risk of reoperative cardiac surgery can be driven down to levels approaching those of primary surgery, a new Cleveland Clinic study...

The investigational bicaval device promises a potential solution for patients with severe TR and right heart failure who currently have no treatment options.

Cleveland Clinic is ranked among the top hospitals in the world for specialized care, including the No.1 hospital in the world for cardiac surgery and cardiology, according to Newsweek’s World’s Best...

Flow measurements to assess graft patency are an important supplement to the surgeon’s clinical judgment during bypass operations. We recap a practical new paper on how to employ and interpret them.

Not all coronary artery bypass operations are created equal. Outcomes are significantly shaped by operative strategy, including conduit choice and target coronary selection, and other key factors...

One of our newest cardiac surgeons shares how he found his surgical passion and how he’s connecting it with doctoral studies in machine learning to try to enhance risk prediction for his patients.

A reputation of fearlessness toward difficult cases drew Dr. Patrick Vargo here, and collegiality is what made him stay. In this Q&A, the young cardiac surgeon also outlines his clinical and research...

Lars Svensson, MD, PhD Chief of Cleveland Clinic Heart, Vascular and Thoracic Institute, joins host, Brian Bolwell, MD, to discuss having courage as a leader.

Our heart surgeons share advice on how to avoid postcardiotomy shock and help ensure success with coronary bypass in patients with left ventricular failure due to ischemic cardiomyopathy.

The investigational device, which uses wireless communication between its pacemaker and defibrillator components, is designed to avoid the long-term problems associated with transvenous ICDs.

For the first time ever in a prospective study, septal myectomy has demonstrated improvements in quality of life and functional capacity in people with symptomatic obstructive hypertrophic cardiomy...

Hani Najm, MD, MSc, FACC, Chair of Pediatric and Congenital Heart Surgery, has been elected to the board of trustees of the American College of Cardiology (ACC).

Most of the half million cardiac surgeries performed in the U.S. each year owe a debt to a milestone operation in a 17-month-old performed at Cleveland Clinic in 1956.

A new JACC State-of-the-Art Review recaps the latest on the incidence and predictors of conduction abnormalities following TAVR, as well as their management and subsequent outcomes.

Multiarterial grafting improves outcomes and is feasible in most CABG candidates. Two of our cardiac surgeons lay out 10 core principles for getting the most out of this revascularization strategy.

Nearly three-quarters of systematic reviews published in high-impact cardiology journals over the past decade achieved “low” or “critically low” scores on the AMSTAR quality tool, a new analysis...

In December, Cleveland Clinic vascular surgeons successfully completed the first surgical case in the MOTION clinical trial of a new non-radiation-based surgical navigation platform for endovascular...

To register for HVTI’s Leadership Series, please visit http://www.ccfcme.org/HVTILeadership/To learn more about the Heart, Vascular & Thoracic Institute, ple...

As the Society for Vascular Surgery’s VQI program evolves, metrics are being refined to focus more on appropriateness of care. Cleveland Clinic is proud to be contributing to those efforts.

Priority for right internal thoracic artery grafting should go to reaching important coronary targets rather than inflow conduit configuration, finds a large retrospective study.

The factor Xa inhibitor failed to demonstrate noninferiority to warfarin in preventing valve thrombosis or thromboembolism in conjunction with the bileaflet On-X mechanical valve.

Dual-chamber pacemakers are the predominant form of CIEDs implanted in the U.S. Potential candidates may have a leadless pacing option if a newly launched international trial proves positive.

The choice between surgical and transcatheter aortic valve replacement must account for individualized clinical and anatomic factors and lifetime management considerations, concludes a new expert...

A novel technique that implants the balloon-expandable valve just 1.5 mm under the noncoronary cusp improves outcomes in transcatheter aortic valve replacement, finds a new Cleveland Clinic study.

We’ve introduced refinements to our novel approach for achieving biventricular conversion in patients with complex anatomic challenges traditionally managed with univentricular conversion.

A review of Cleveland Clinic experience finds transaxillary TAVR has outcomes comparable to those with transfemoral TAVR and superior to those with transthoracic approaches.

Our experts profile the rationale behind — and potential future of — four interventional approaches to treating heart failure that are currently in clinical trials.

As more patients benefit from TEVAR, larger numbers survive to the point where their aortic disease progresses. Cleveland Clinic recently reported the world’s largest experience in extending and...

2020 marks the 30th anniversary of the first successful human endovascular aneurysm repair, performed by Juan Parodi, MD. We look back on his early work on EVAR while a trainee at Cleveland Clinic...

Repair is feasible in over 95% cases of mitral valve prolapse and yields better outcomes than replacement, provided that these best practices are followed.

We share details and learnings from one of the very few double-lung transplants performed to date in this highly challenging clinical context.

A study showing good early outcomes after isolated tricuspid valve surgery supports expanding surgical candidacy criteria and operating earlier on patients with functional tricuspid regurgitation.

Shortcomings in performing complex cardiac operations among early- and late-career surgeons can be mitigated by institutional and individual surgeon experience and a culture of safety and teamwork, a...

In a propensity-matched analysis of patients with thoracic or thoracoabdominal aortic aneurysms, short-term results favor endovascular repair but outcomes at 5 to 10 years favor open surgery.

Until a durable, anticoagulation-free valve prosthesis is developed, preservation of a well-functioning bicuspid aortic valve may be the best course in the setting of isolated ascending aortic...

Aortic neck diameter is among the most important predictors of success in endovascular repair of abdominal aortic aneurysms, concludes a new meta-analysis.

A large cohort study shows that valve reimplantation in these patients can provide excellent event-free survival and aortic valve function without the need for anticoagulation conferred by mechanical...

If the findings of a new retrospective study are confirmed in a randomized controlled trial, phosphodiesterase-5 inhibitors could become standard of care in this setting.

Multidisciplinary management with emergency primary aortic repair and additional peripheral revascularization can improve outcomes, especially when delivered in a timely manner.

The jury is still out on whether patients with degenerative mitral regurgitation and less than severe tricuspid regurgitation should undergo tricuspid annuloplasty along with mitral valve surgery.

Our world-leading experience in this procedure confirms that it reduces stroke risk in high-risk patients and can be safely combined with TAVR as well as atrial fibrillation ablation.

Ex vivo lung perfusion is a major reason why Cleveland Clinic was among just four U.S. centers to surpass 100 lung transplants in 2020. We share learnings from our burgeoning perfusion program.

Operator safety has been a driving force behind the development of robotic technology for cath lab procedures, but likely patient benefits appear to be emerging as well. We share our early insights.

A practical new review article surveys the benefits and limitations of 3D-printed heart replicas in clinical practice, and offers advice for those considering adopting the technology.

Sixteen-week results of the VALOR-HCM trial suggest that a noninvasive treatment option may soon be at hand for severe obstructive hypertrophic cardiomyopathy, if findings are sustained over longer...

We’re successfully offering a new minimally invasive, single-incision procedure to patients who need surgery to address both mitral valve disease and hypertrophic obstructive cardiomyopathy.

ECMO and other forms of mechanical circulatory support have a role in cases involving either respiratory failure or cardiac failure, but generally not both. An expert surgeon reviews management...

A team led by Stanley Hazen, MD, PhD, receives the first “Program Project” award focused on the gut microbiome. Three related research projects will be supported in a quest for new mechanistic and...

There are shortfalls in contemporary techniques for surgical repair of anomalous pulmonary veins (APVs) that are remote from the left atrium. In this article, pediatric and congenital heart surgeons...

Three of our valve disease experts reflect on notable changes and developments related to mitral valve disease in the new guideline update.

Intermediate-term results from the multicenter REGROUP trial show continued safety of endoscopic harvesting of saphenous vein grafts in patients undergoing coronary bypass.

An analysis of the INTERMACS registry finds that use of phosphodiesterase 5 inhibitors after LVAD placement improves survival and reduces thrombotic events, setting the stage for a randomized trial.

We’ve adopted a new multidisciplinary approach for providing preemptive hemodynamic support to enable VT ablation in patients otherwise too vulnerable to procedural risks.

Three of our valve disease experts reflect on key changes and developments related to aortic valve disease in the new guideline update.

Our surgeons and electrophysiologists have given the hybrid Convergent procedure for persistent AF a new twist by adding ablation of the ligament of Marshall and a left atrial appendage clip.

A dynamic infographic shares our latest volume and outcomes data across these three key surgical areas.

Check out this infographic-style recap of our latest outcome and volume data in three key surgical and procedural areas.

An objective means for quantifying the myocardial mass supplied by each potential arterial target could optimize long-term survival in coronary bypass surgery, a large cohort study suggests.

Cleveland Clinic researchers have validated the use of remote cardiac telemetry as a “no touch” alternative to standard 12-lead ECG for reliable continuous QTc monitoring.

The Chairman of our Heart, Vascular & Thoracic Institute shares a glimpse of our preparatory planning and how we’re now pivoting for a return to more procedures for more patients.

A new JACC statement makes the case for earlier referral of patients with advanced heart failure. Our experts review the recommendations and the rationale behind them.

A new study shows that network clustering is a rapid and clinically intuitive means of predicting cardiac risk in cancer survivor, with NT-proBNP and troponin T identified as leading biomarkers of...

Through five years of follow-up, no cases of valve thrombosis or structural valve deterioration were observed with a bioprosthesis using the new Resilia tissue technology.

When patients present with angina but have little or no evidence of plaque in their coronary arteries, suspect ischemia with non-obstructive coronary arteries.

The case of a 30-something woman illustrates why this infrequently used operation is a valuable alternative to aortic valve replacement in young patients, particularly those with prior heart surger...

In some patients, septal myectomy may be necessary but not sufficient. We share our imaging-informed, multidisciplinary approach to individualizing treatment in these cases.