Kotaro Nakanishi
@ktr_nakanishi
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Professor @nakanishi_lab (https://t.co/vzeuy2d0hF)/ cityRNAs and tityRNAs/Jazz and Techno. π¦ https://t.co/DkY22WE4nr
Columbus, OH
Joined August 2018
Just published! AGOs loaded with tinyRNAs recognize specific target sequences in the 5' upstream region of the target site πππ
πππππ
πππππ of the guide. We devised π©πππππππ to load cityRNAs into endogenous AGOs, causing gene silencing.
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RT @NatureBiotech: RNA structures are built from cryogenic electron microscopy maps using deep learning and backbone tracing
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RT @NIH: Last year, $9B of the $35B that the National Institutes of Health (NIH) granted for research was used for administrative overhead,β¦
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Structural and mechanistic insights into the activation of a short prokaryotic argonaute system from archaeon Sulfolobus islandicus | Nucleic Acids Research | Oxford Academic
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Cytoplasmic mRNA decay and quality control machineries in eukaryotes | Nature Reviews Genetics
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Argonaute2 modulates megakaryocyte development and sex-specific control of platelet protein expression and reactivity | Scientific Reports
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Tissue-specific modulation of CRISPR activity by miRNA-sensing guide RNAs | Nucleic Acids Research | Oxford Academic
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RT @NIbtehaz: I am excited to share that our paper "NuFold: end-to-end approach for RNA tertiary structure prediction with flexible nucleobβ¦
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RT @Nature: Mice injected with a microRNA molecule lived longer and had fewer markers of ageing, but itβs not yet known if the treatment woβ¦
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RT @PetzoldKatja: π· Interested in computational #NMR ? Join us in beautiful Switzerland in June! Many slots for selected talks and great hiβ¦
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RT @SvobodaLab: The Argonautes 2025 are in their infancy but moving ahead! The organizers (@farmgirlphd, @DinaGrohmann, @MeisterLab + me) sβ¦
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Structural insights into RNA cleavage by PIWI Argonaute | Nature
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rRFtargetDB: a database of Ago1-mediated targets of ribosomal RNA fragments
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Importance of an N-terminal structural switch in the distinction between small RNA-bound and free ARGONAUTE | Nature Structural & Molecular Biology
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RT @DCSwarts: π¨New reviewπ¨ Evolution and ecology of anti-defence systems in phages and plasmids Link: https://t.cβ¦
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RT @CityTx_: Welcome to City, Andy Orth! Weβre happy to share Andyβs appointment as CEO, bringing over 25 years of industry leadership expeβ¦
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RT @dsgoodsell: I'm also very happy to announce that @ludovic_autin will be continuing the cell modeling work, so stay tuned for exciting dβ¦
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Distribution of bacterial DNA repair proteins and their co-occurrence with immune systems: Cell Reports
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Top 3K+ Soonicorns in United States in Jan, 2025 - Tracxn
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Argonaute proteins regulate the timing of the spermatogenic transcriptional program | bioRxiv
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