Thrilled to announce that ELATUS is out in @NatureComms! ELATUS uncovers functional lncRNAs in scRNA-seq missed due to poor annotation, such as AL121895.1, involved in breast cancer, providing insights into lncRNA biology. @MaiteHuarteLab @mikelhernaez

RT @CIMA_unav: 📢 Progress from Cima: researchers develop ELATUS, a tool that detects long non-coding RNAs (lncRNAs), key in diseases such a…

RT @CIMA_unav: 🔬 Breakthrough in the fight against cancer! Scientists at Cima identify the YTHDC1 protein as a key regulator of p53, the ‘g…

RT @RNASeqBlog: RNA sequencing with the ELATUS tool is helping reveal the role of long non-coding RNAs (lncRNAs) in disease, advancing insi…

@_prashantbhat @NatureComms @MaiteHuarteLab @mikelhernaez Thanks a lot Prashant!

RT @martinalexsmith: 💥Cheeky 'little' update from @GencodeGenes v47, almost doubling the number of #lncRNA genes & ~4x more lncRNA transcri…

RT @MaiteHuarteLab: 🚨 Paper Alert! 🚨 Does RNA regulation impact the p53 pathway and DNA damage response? We reveal distinct m6A-dependent a…

RT @lpachter: A lot of bioinformatics requires editing sequencing reads to facilitate QC and make them suitable for processing. To help wit…

RT @MartaMontes3: 👇👇Don´t miss it! BRIDGING RNA BIOLOGY AND THERAPY: Exploring the Frontiers of Advanced Medicine. Join us in beautiful Pa…

@_prashantbhat @Nature Congratulations Prashant!! Amazing work!

RT @DanielRamirez99: Y para celebrar el Día del Libro también… una sugerencia fuera de carta.

RT @EtienneSollier: Introducing figeno, my visualization software for (epi)genomics🧬🎨. Supports many data types (bigwig, HiC, @nanopore dat…

RT @raimondi_ivan: Thrilled to finally share this work! @MaiteHuarteLab and I delve into the interplay between RNA regulation and DNA damag…

RT @MaiteHuarteLab: 🚨 Bridging RNA Biology and Therapy Symposium!! Join us in beautiful Pamplona, October 9th-10th, with amazing speakers…

RT @CIMA_unav: 👩‍🔬Compartimos este artículo divulgativo de nuestra investigadora @MartaMontes3 sobre la #senescencia celular, el proceso de…

RT @biorxiv_bioinfo: Uncovering functional lncRNAs by scRNA-seq with ELATUS #biorxiv_bioinfo

@Steffen_E_Fuchs @MaiteHuarteLab @mikelhernaez Thanks! Great point! We mention this in the discussion. At this point, ELATUS is designed for 10x Genomics data, which as you said targets only polyA RNAs. But, of course, its application to alternative protocols for both polyA and non-polyA RNAs could even improve its detection.

@FortesLab Thanks a lot also for your great contribution to this work Puri!!

(11/11) The proposed workflow, ELATUS (available in R), defines a set of functional lncRNAs in scRNA-seq enhancing its transcriptional knowledge. Its adaptability to diverse preparation (e.g., full-length) and annotation schemes, such as pre-mRNA, deserves further investigation.