Laura Keller
@kellerlauraj
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Chemoproteomics all the way! Genentech scientist | former PhD student in the Bogyo lab at Stanford she/her | tweets are my own
Joined September 2013
RT @ChemBio_John: Check out our latest work on Plasmodium with @fidocklab where we explored a novel set of mixed alkyl/aryl phsophonates as…
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RT @mbogyo: Check out our latest work targeting the malaria proteasome. Another outstanding collaboration with @fidocklab. Congrats to @Che…
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Check out this awesome preprint showing the power of covalent macrocycles as antimalarials! Incredible potency, selectivity, and stability. Congrats to @ChemBio_John, @RyanKMuir, @mbogyo, and all of the stellar collaborators!
It's all about covalent inhibitors! See how covalent macrocycles that target the malaria proteasome can prevent resistance. Great work from the Bogyo lab @ChemBio_John in collaboration with @fidocklab.
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suggesting a noncatalytic function for BT4193. Overall, we show that gut bacterial serine hydrolases can be drugged, play vital roles in gut physiology, and can (although luckily for diabetic patients not in this case) be potential off-targets that should be investigated! [4/4]
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Congrats @FrancoFaucher!! Check this cool paper out!
Paper just published. That was fast! Solid Phase Synthesis of Fluorosulfate Containing Macrocycles for Chemoproteomic Workflows - Faucher - Israel Journal of Chemistry - Wiley Online Library
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Congrats to my favorite microbiologist @GerrickElias and the @HowittLab for getting this preprint out! Check out this cool story on a new protist and its dynamics with the gut microbiota!!
So thrilled to share this story! We dive into the biology of commensal protists in the microbiota, looking at diversity of their metabolic input/output and how this affects interactions with the host and their bacterial counterparts in the microbiome!
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If you're looking to start your PhD at the super exciting intersection of chemical biology and microbiome research, I couldn't recommend a better lab! You couldn't ask for a smarter or more thoughtful mentor.
Interested in unraveling how the #microbiome modulates health and disease? Come join my new lab at @UniJena! We have two #PhDpositions in #ChemicalBiology Synthesis: Biochemistry: #chemjobs #chemPhD #ChemTwitter #microverse_exc 1/3
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So excited to finally be sharing this story!! Thank you to the many collaborators (including @taylorhnguyen in KC Huang's lab, the teams of @ajodonoghue, @MJNiphakis and Ami Bhatt, and my mentor @MLakeme) for helping me and @mbogyo bring this story to life!
Our first paper on our efforts mapping serine hydrolases in gut commensal bacteria is out. We identified a homolog of the human DPP4 protease in B. theta that is important for community fitness.
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Couldn’t recommend his lab more! One of the most thoughtful scientists I’ve had the pleasure to work with.
I'm searching for a PhD student to start in my brand new lab @UniofBath in Oct 2022. The project will use phage display for covalent ligand discovery. Retweets are much appreciated.
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@ChemSysBio Please register here for this webinar After registering, you should receive a confirmation email containing information about joining the webinar. If you cannot attend, a recording of the webinar will be posted afterwards at
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Congratulations to my favorite KLK aficionado!
Very happy that our KLK paper has found a home in @J_A_C_S ! We use selective ABPs to dissect a complex proteolytic network in prostate cancer. A huge thanks to my great mentor @TateScience and our collaborators Judith Clements and @TomaKryza @QUT
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Congratulations to Ouma, @BrettMBabin, and @MLakeme !!
After much hard work and a long time in the works, our paper on the roles of a family of serine hydrolases in T. gondii is out! @BrettMBabin @MLakeme @longlabstanford
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@mbogyo @VerhelstLab We're going to see the Jonas Brothers on August 27 if you wanna join!! 🙃 @malycat03 @ChemBio_John @FrancoFaucher
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RT @scottlovell34: Check out our paper on 'substrate-biased' activity-based probes that is out today in @nchembio! A great collaboration be…
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RT @SedonaMurphy: Thrilled to watch this webinar by @DrIbram on Antiracism in Biomedical Research and Medicine! Science is not free from th…
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