Jocelyn Kaiser
@jocelynkaiser
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I'm a reporter covering NIH and biomedical research policy for Science magazine.
Joined February 2009
How is replicating a cancer study like baking a cake? See my feature http://t.co/0V2ObFRdaV.
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WOW. Novartis is buying the gene therapy firm AveXis for $8.7 billion. Here's my 2017 story on how their treatment is saving babies with spinal muscular atrophy, a fatal neuromuscular disease.
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Shutdown over, but a total of 19 NIH study sections delayed because of Federal Register snafu (backround
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The office that polices research fraud in US-funded biomedical labs is in turmoil. Read our scoop
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Why using CRISPR to repair broken genes in sick people won't be easy
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Gene therapy delivered into the blood saves kids with a deadly spinal disease. Next: muscle and brain diseases.
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Researchers have homed in on several common genes that may explain why some people become severely ill from covid-19--and that point to possible treatments @kennethbaillie @covid19_hgi
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Huge news today--first FDA-approved gene therapy for an inherited disease. I profiled the couple behind it back in 2009 (with editor @laurahelmuth)
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@cristenw @HeidiRehm @merrymanlab @skathire @JACCJournals @ACCinTouch @NEJM Hey @ASAPbio_ and other preprint folks: @nejm has finally put its policy in writing (see correction notice here .
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NIH says its All of Us health study is on track to recruit 1 million volunteers in 5-6 years. The bigger worry: keeping them from dropping out. #AllofUs, @allofusresearch
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My story on Obama precision medicine plan: A genetic biobank on 1 million Americans. http://t.co/J7Ls5nzdDu.
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Yesterday in Boston, President Biden spoke of cancer prevention vaccines and blood tests for early cancers. Read more about both here
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New data from #datahound show ongoing "cull" of NIH PIs http://t.co/skbiYq1pZ3
http://t.co/VkipfQ06uM
http://t.co/2ZHVvIefoH.
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A star gene therapy researcher's's dark history of alleged sexual harassment in the lab is revealed in this meticulously reported story by @meredithwadman
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Just before covid stopped travel, I met with Costa Rica's rising stars in tropical biology who are coming home to study their country's rich biodiversity. @AndreaGVincent #UCR @ICFJKnight @PuntoyAparte_1 #ICFJ @ICFJ #UCR
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Because of COVID-19, NIH is urging that all large meeting held at NIH or organized by NIH be held virtually by video or postponed or cancelled. That includes study sections, as first reported by @MedResJourno
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At Senate hearing, @NIHDirector just announced that NIH has suspended enrollment in controversial study of moderate alcohol consumption pending investigation. background:
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Good news for AIDS community: Moderna will no longer exclude HIV positive people from its large covid-19 vaccine study. But that's just one company's trial.
Today, we are sharing an important update about our protocol for the Phase 3 COVE Study of mRNA-1273, our vaccine candidate against COVID-19.
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Scientists and now university groups protest new NIH clinical trials definition Background:
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My story on the odd tale of a woman whose fractured chromosome cured her disease. http://t.co/Mn0Q4NeBh0.
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More than 1400 have signed petition protesting NIH plan to classify basic brain studies as clinical trials
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Personalized cancer vaccines may help keep melanoma in check and shrink tumors in combo with checkpoint inhibitor.
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I went to Riyadh to learn how Saudi geneticists are striving to prevent rare diseases in their country. My story:
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@BiophysicalFrog @FORsymp @NIHDirector It's the Administrative Procedure Act--applies to HHS agencies but not NSF, apparently. See
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HHS Sec Price confirms at House hearing that indirect costs are target of Trump NIH budget: "about 30% of grant money" goes to indirects.
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Does it matter that 19% of sample so far is from Arizona (2% of US pop) and 59% are women? #AllOfUS.
#allofus is also well-positioned to examine whether differences in health outcomes reflect variable pathogenesis of disease X by group, or if they are largely driven by failings of the health care system in these communities. The policy implications of this would be massive.
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Watching webcast: Risks and Benefits of Gain-of-Function Research: A Symposium: http://t.co/p6urtCvTr0.
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Spurred by pandemic, U.S. government will revisit federal policies on risky virus research
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Thanks to @jorisveltman and @dgmacarthur for their help with my story on human genetics in Saudi Arabia
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Good news for MERS researchers: NIH exempts animal model work from pause on risky virology studies http://t.co/ZHIrFdUA3C
#GOF, #MERS.
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Yes it may be. More on study here. and here
Far as I know this if the first large-scale implementation of a "liquid biopsy" screening test that looks for *many* cancers at once.
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Tom Price, HHS nominee, says he will support science, "make sure factual information is conveyed".
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"The horror case," says Fineberg: high path, transmissibility in mammals, evasion to countermeasures. Subarrao says regs restrict.
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An NIH question! Price says he supports efforts to boost funding for Alzheimer's research.
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Senate subcommittee approves $2B increase for NIH in 2018. Details to come.
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@martinenserink yes, one newsy tidbit: USG decision on paused studies put off to mid 2016 #NSABB.
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NIH has corrected earlier figure--only 16 meetings rescheduled. NIDCD meetings did or will occur on schedule.
Shutdown over, but a total of 19 NIH study sections delayed because of Federal Register snafu (backround
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Obama's $1B raise for NIH in 2016 boosts BRAIN initiative, Alzheimer's, vaccines, precision med, antibiotics@ScienceInsider.
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Monthly FOIA logs--what a concept! How I wish @NIH did this.
Things I enjoyed about this Tweet (in no particular order): 1) Wonky reg humor = comic gold; 2) I <3 students using mechanisms of govt transparency; 3) I enjoy discovering new (to me) public universities like @letsgopeay; 4) I have an excuse to hum @SpongeBob theme.
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Just back from a fantastic week in Costa Rica with @ICFJKnight journalism exchange. Many thanks to my excellent host, Silvia from @PuntoyAparte_1, and to the many journalists and scientists who met with me. #ICFJ @ICFJ #UCR #UNA #ITCR #SINAC
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Yesterday's #NSABB meeting: Last October's 1-year "pause" on risky virology studies will now last ~21 months.
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@katewbauer @JasonSynaptic @thebyrdlab @Maratosflier From my notes from the June 2018 ACD meeting, NIH is hoping to get to 1100 ESIs this year, up from 1040 in 2017 (so not a huge increase).
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Two new studies from Reproducibility Project: Cancer Biology reproduced some, but not all original results. 9 (of 29) now out, just 4 fully replicated. background:
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Scientists question the usefulness and validation of a saliva-based genetic test for #COVID19 severity now sold in the United States.
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NIAID's Kana Subbarao makes plea to lift funding pause for rodent studies and MERS, flu strains that emerged in 2014.
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That's right--corresponding authors are what bioRxiv gave us. But if you look at coauthors the list would be different--eg 50 for @dalygene
@ClausWilke @EricTopol @jocelynkaiser @erlichya I think the article refers to most preprints as corresponding author.
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Subbarao, Michael Imperiale: Need more precise term than "gain of function," which is too broad, covers routine virology studies.
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Flu projects in limbo while NIH decides which must stop under gain of function moratorium. See the letters here. http://t.co/qzbw3YVWM1.
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Yes, NIH says they'll look at intramural too
.@jocelynkaiser Will grant limits affect @IRPatNIH vs @NIHgrants PIs equally? 50% intramural PIs have >$1.2M, yet < 6% extramural PI do.
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As expected, Trump 2018 budget plan slashes NIH overhead payments (indirect costs) to 10% (from current 30% avg)
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Top U.S. Scientific Misconduct Official Quits in Frustration With Bureaucracy http://t.co/Ih1ntQtB7y.
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It was a delight to meet Evelyn, saved by gene therapy from the disease that took her big sister.
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Price: evidence clear that HIV causes aids, abortions do not cause breast cancer. unfamiliar with claim that immigrants spread leprosy.
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Saw that study finding men get $40,000 more for their first NIH grant? We took a closer look.
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Doesn't sound too drastic
Does anyone know exactly what "Restructure NIH’s administrative functions to ensure operations are effective and efficient" means in terms of what will happen?.
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Puzzled by slamming of NIH award for oldsters to wind down labs. Isn't idea to make room for young? http://t.co/VYEBzAMX1c
#emeritusNIHGrant.
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