@hagilani @captainchloride I second this request for link, thanks!

RT @gunnar_heine: APPLAUSE, APPLAUSE @VladoPerkovic @IgAN_JBarratt @BradRovin et al Iptacopan reduces proteinurie (PU) in IgA NP 🐘1: Is the…

RT @kidney_boy: Last one Tacro or MMF for steroid dependent of frequently relapsing nephrotic syndrome #KidneyWk

RT @willkidney: Nice summary from the @Oxford_NDPH team: “ …while empagliflozin continues to have some benefit after stopping treatment, t…

@AlanYuNeph @sarahkmels @CJASN Can’t access - do they say why DAPA-CKD not in table? Looks to support eGFR slope data from EMPA-KIDNEY. However as you know a risk calculator may say your example patients 5 year ESKD risk is 1/1000, so if only eGFR indication still learning how to ‘draw the line’ on this issue

RT @NephJC: Welcome to #TenTweetNephJC ✳️10 tweets #NephJC catch-up ✳️ What is the best systolic BP in patients with high-risk CV comorbidi…

Nice review of one of my least favourite diagnoses. Not sure I believe it accounts for as many as 1 in 20 cases of urinary tract obstruction though…

@TWhittier_RUSH @askrenal Thanks!

@LewisStanding1 @askrenal Decrease in intraglomerular hyperfiltrarion with the things that are good for kidneys in longterm - ACEi/SGLT2i/nsMRA - so see that drop in eGFR initially but push through as slow rate of eGFR progression on longterm follow-up (which is what we care about) with these agents.

@rmohty @askrenal Absolutely perfect, thank you very much for your help!

Giving a talk. We all know & love the shape of this graph for recent Flozin / Finerenone trials. Can’t find similar graph for older ACEi/ARB trials (RENAAL etc) - anyone have them from the literature? @askrenal #AskRenal

@JasmineNephro @ManualOMedicine As I comment every time - every algorithm should have ESKD as an explicit exclusion criteria from following it.

Another exciting day in IgA Nephropathy

RT @NephJC: T3d Long-term data (we’re talking 45 years+) on patients post nephrectomy suggesting little harm came from World War II vetera…

Summary of latest publication looking at safety of kidney donation with 7 year follow-up.

RT @AmitXGarg: #NephJC In my mind the key clinical implications. 1. Carefully selected standard criteria living kidney donors can be coun…

@jfdwolff @kidney_bow @kidney_boy @hswapnil @NeillDuncan3 Plasminogen activation of ENaC a fun story too! Prob combination of factors - the liver does stupid things with ⬆️clotting factors too (see also: hypercholesterolaemia) but urine losses must be important given predilection of clots for renal veins. LMWH certainly works though 🤷‍♂️